IE20000315A1 - Pharmaceutical compositions containing selective PDE-5 inhibitors - Google Patents

Pharmaceutical compositions containing selective PDE-5 inhibitors

Info

Publication number
IE20000315A1
IE20000315A1 IE20000315A IE20000315A IE20000315A1 IE 20000315 A1 IE20000315 A1 IE 20000315A1 IE 20000315 A IE20000315 A IE 20000315A IE 20000315 A IE20000315 A IE 20000315A IE 20000315 A1 IE20000315 A1 IE 20000315A1
Authority
IE
Ireland
Prior art keywords
pde5
sexual dysfunction
pde5 inhibitor
inhibition
article
Prior art date
Application number
IE20000315A
Other languages
English (en)
Inventor
Kenneth Michael Ferguson
Jeffrey Thomas Emmick
John Steven Whitaker
Original Assignee
Lilly Icos Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22452153&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE20000315(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Icos Llc filed Critical Lilly Icos Llc
Publication of IE20000315A1 publication Critical patent/IE20000315A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Glass Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
IE20000315A 1999-04-30 2000-04-26 Pharmaceutical compositions containing selective PDE-5 inhibitors IE20000315A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13203699P 1999-04-30 1999-04-30

Publications (1)

Publication Number Publication Date
IE20000315A1 true IE20000315A1 (en) 2001-03-07

Family

ID=22452153

Family Applications (1)

Application Number Title Priority Date Filing Date
IE20000315A IE20000315A1 (en) 1999-04-30 2000-04-26 Pharmaceutical compositions containing selective PDE-5 inhibitors

Country Status (47)

Country Link
EP (2) EP1415652A3 (US20040097461A1-20040520-C00035.png)
JP (2) JP4975214B2 (US20040097461A1-20040520-C00035.png)
KR (2) KR20010020779A (US20040097461A1-20040520-C00035.png)
CN (2) CN1196487C (US20040097461A1-20040520-C00035.png)
AT (1) ATE251908T1 (US20040097461A1-20040520-C00035.png)
AU (3) AU769946C (US20040097461A1-20040520-C00035.png)
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DZ (1) DZ3171A1 (US20040097461A1-20040520-C00035.png)
EA (2) EA005416B1 (US20040097461A1-20040520-C00035.png)
ES (2) ES2187234A1 (US20040097461A1-20040520-C00035.png)
FI (1) FI20000976A (US20040097461A1-20040520-C00035.png)
FR (1) FR2795646B1 (US20040097461A1-20040520-C00035.png)
GB (1) GB2351663A (US20040097461A1-20040520-C00035.png)
GR (1) GR1003575B (US20040097461A1-20040520-C00035.png)
HK (1) HK1041204B (US20040097461A1-20040520-C00035.png)
HR (2) HRP20000243A2 (US20040097461A1-20040520-C00035.png)
HU (2) HUP0001632A3 (US20040097461A1-20040520-C00035.png)
ID (1) ID25704A (US20040097461A1-20040520-C00035.png)
IE (1) IE20000315A1 (US20040097461A1-20040520-C00035.png)
IL (3) IL135817A0 (US20040097461A1-20040520-C00035.png)
IT (1) ITMI20000922A1 (US20040097461A1-20040520-C00035.png)
LT (1) LT4758B (US20040097461A1-20040520-C00035.png)
LU (1) LU90569B1 (US20040097461A1-20040520-C00035.png)
LV (1) LV12560B (US20040097461A1-20040520-C00035.png)
MX (2) MXPA00003997A (US20040097461A1-20040520-C00035.png)
NL (1) NL1015027C2 (US20040097461A1-20040520-C00035.png)
NO (2) NO20002097L (US20040097461A1-20040520-C00035.png)
NZ (2) NZ504163A (US20040097461A1-20040520-C00035.png)
PE (1) PE20010071A1 (US20040097461A1-20040520-C00035.png)
PL (2) PL339897A1 (US20040097461A1-20040520-C00035.png)
PT (2) PT102457A (US20040097461A1-20040520-C00035.png)
SE (1) SE0001518L (US20040097461A1-20040520-C00035.png)
SG (1) SG98384A1 (US20040097461A1-20040520-C00035.png)
SI (2) SI20361A (US20040097461A1-20040520-C00035.png)
SK (1) SK285415B6 (US20040097461A1-20040520-C00035.png)
SV (1) SV2002000055A (US20040097461A1-20040520-C00035.png)
TR (1) TR200001132A3 (US20040097461A1-20040520-C00035.png)
UA (1) UA72248C2 (US20040097461A1-20040520-C00035.png)
WO (1) WO2000066099A2 (US20040097461A1-20040520-C00035.png)
ZA (2) ZA200002058B (US20040097461A1-20040520-C00035.png)

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Publication number Priority date Publication date Assignee Title
EP1200090B1 (en) * 1999-08-03 2013-09-11 ICOS Corporation Pharmaceutical formulation comprising a beta-carboline and its use for treating sexual dysfunction
DE10010612A1 (de) * 2000-03-03 2001-09-27 Merck Patent Gmbh Verwendung von PDE V-Inhibitoren
JP2004533402A (ja) * 2000-06-08 2004-11-04 リリー アイコス リミテッド ライアビリティ カンパニー Ｐｄｅｖインヒビターとしての四環系ジケトピペラジン化合物
CA2423357C (en) 2000-08-02 2008-05-27 Lilly Icos Llc Fused heterocyclic derivatives as phosphodiesterase inhibitors
ES2286291T3 (es) 2001-06-05 2007-12-01 Lilly Icos Llc Compustos tetraciclicos como inhibidores de pde5.
GB0129274D0 (en) * 2001-12-06 2002-01-23 Pfizer Ltd Novel kit
US20060205733A1 (en) * 2004-08-26 2006-09-14 Encysive Pharmaceuticals Endothelin a receptor antagonists in combination with phosphodiesterase 5 inhibitors and uses thereof
MX2008012495A (es) 2006-03-28 2009-01-07 Javelin Pharmaceuticals Inc Formulaciones de dosis baja de diclofenaco y beta-ciclodextrina.
US7495024B2 (en) 2006-08-07 2009-02-24 Via Pharmaceuticals, Inc. Phenylalkyl N-hydroxyureas for combating atherosclerotic plaque
DE102007028869A1 (de) 2007-06-22 2008-12-24 Ratiopharm Gmbh Verfahren zur Herstellung eines Arzneimittels enthaltend Tadalafil
DE102009033396A1 (de) 2009-07-16 2011-01-20 Ratiopharm Gmbh Wässrige Lösung und gelatinierte Zusammensetzung umfassend einen Phosphodiesterase-5-Inhibitor sowie diesbezügliche Verfahren und Verwendung
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
US20110136815A1 (en) 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US20110263606A1 (en) * 2010-04-26 2011-10-27 Horst Zerbe Solid oral dosage forms comprising tadalafil
EP2672959A1 (en) 2011-02-10 2013-12-18 Synthon BV Granulated composition comprising tadalafil and a disintegrant
WO2012107541A1 (en) 2011-02-10 2012-08-16 Synthon Bv Pharmaceutical composition comprising tadalafil and a cyclodextrin
WO2012107092A1 (en) 2011-02-10 2012-08-16 Synthon Bv Pharmaceutical composition comprising tadalafil and a cyclodextrin
KR102239291B1 (ko) 2013-06-28 2021-04-14 한미약품 주식회사 타다라필 또는 이의 약학적으로 허용가능한 염을 포함하는 저작정 제제
KR101663238B1 (ko) 2013-11-15 2016-10-14 한미약품 주식회사 타다라필 및 암로디핀을 포함하는 복합 고형 제제
KR102646431B1 (ko) 2017-09-29 2024-03-12 한미약품 주식회사 생산성 및 균일성이 개선된 타다라필을 함유하는 고형제제 및 그 제조방법
US20210137919A1 (en) * 2018-02-07 2021-05-13 Smawa Gmbh Pharmaceutical formulations, method for producing a pharmaceutical formulation, and medicament comprising same

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GB9301192D0 (en) * 1993-06-09 1993-06-09 Trott Francis W Flower shaped mechanised table
GB9401090D0 (en) 1994-01-21 1994-03-16 Glaxo Lab Sa Chemical compounds
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IL126951A0 (en) 1996-05-10 1999-09-22 Icos Corp Carboline derivatives
CA2288910C (en) * 1997-04-25 2003-06-24 Pfizer Inc. Pyrazolopyrimidinones for sexual dysfunction
WO1999059584A1 (en) * 1998-05-20 1999-11-25 Schering Corporation Combination of phentolamine and cyclic gmp phosphodiesterase inhibitors for the treatment of sexual dysfunction
AU1025899A (en) 1998-09-16 2000-04-03 Icos Corporation Carboline derivatives as cgmp phosphodiesterase inhibitors
US6743443B1 (en) * 1998-10-05 2004-06-01 Eisai Co., Ltd. Tablets immediately disintegrating in the oral cavity
EP1161255A4 (en) * 1999-03-08 2002-07-17 Merck & Co Inc METHOD AND MEANS FOR TREATING ERECTILE DYSFUNCTION
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US6451807B1 (en) * 1999-04-30 2002-09-17 Lilly Icos, Llc. Methods of treating sexual dysfunction in an individual suffering from a retinal disease, class 1 congestive heart failure, or myocardial infarction using a PDE5 inhibitor

Also Published As

Publication number Publication date
EP1415652A3 (en) 2004-05-12
KR20020008396A (ko) 2002-01-30
CH692478A5 (de) 2002-07-15
HUP0200912A3 (en) 2003-07-28
CO5170493A1 (es) 2002-06-27
CN1384746A (zh) 2002-12-11
NO20002097D0 (no) 2000-04-25
FI20000976A (fi) 2000-10-30
CA2371684C (en) 2007-10-23
GR1003575B (el) 2001-05-14
SK15632001A3 (sk) 2002-02-05
EA200000355A3 (ru) 2001-02-26
ATE251908T1 (de) 2003-11-15
NO20015275L (no) 2001-12-06
BR0010181A (pt) 2003-02-25
PT102457A (pt) 2000-11-30
ITMI20000922A0 (it) 2000-04-26
HU0200912D0 (en) 2002-04-29
FI20000976A0 (fi) 2000-04-26
PL197813B1 (pl) 2008-04-30
ES2208317T7 (es) 2015-09-15
AU769946C (en) 2005-01-13
DE10021266A1 (de) 2000-11-16
HRP20010778B1 (en) 2005-04-30
MXPA01010837A (es) 2002-11-07
SI20361A (sl) 2001-04-30
JP2002543116A (ja) 2002-12-17
DZ3171A1 (US20040097461A1-20040520-C00035.png) 2000-11-09
PE20010071A1 (es) 2001-03-22
LU90569B1 (fr) 2002-02-27
HK1041204B (zh) 2004-03-05
NL1015027A1 (nl) 2000-10-31
ES2187234A1 (es) 2003-05-16
CA2307101A1 (en) 2000-10-30
DK1173181T3 (da) 2004-02-16
AU4490800A (en) 2000-11-17
BR0003046A (pt) 2002-07-23
NO20002097L (no) 2001-10-26
DE20007861U1 (de) 2000-08-24
DK1173181T6 (en) 2015-04-27
ZA200108900B (en) 2003-03-26
TR200001132A2 (tr) 2001-01-22
SE0001518D0 (sv) 2000-04-26
LT4758B (lt) 2001-02-26
CZ296534B6 (cs) 2006-04-12
GB0010199D0 (en) 2000-06-14
IL135817A0 (en) 2001-05-20
NO20015275D0 (no) 2001-10-29
IL146098A0 (en) 2002-07-25
LV12560B (en) 2001-04-20
PL352629A1 (en) 2003-08-25
CN1292264A (zh) 2001-04-25
AU2004201988A1 (en) 2004-06-10
GB2351663A (en) 2001-01-10
BE1012957A5 (fr) 2001-06-05
DK200000677A (da) 2000-10-31
CA2371684A1 (en) 2000-11-09
CH1173181H1 (US20040097461A1-20040520-C00035.png) 2019-07-15
JP4975214B2 (ja) 2012-07-11
LV12560A (en) 2000-11-20
HRP20000243A2 (en) 2001-12-31
SV2002000055A (es) 2002-07-03
AU3012900A (en) 2000-11-02
AU769946B2 (en) 2004-02-12
EA200101008A1 (ru) 2002-04-25
IL146098A (en) 2007-06-03
PL339897A1 (en) 2000-11-06
DE60005940D1 (de) 2003-11-20
KR100577057B1 (ko) 2006-05-10
CZ20013879A3 (cs) 2002-04-17
EA005416B1 (ru) 2005-02-24
HU230369B1 (hu) 2016-03-29
DE60005940T3 (de) 2015-08-27
WO2000066099A3 (en) 2001-01-18
WO2000066099A2 (en) 2000-11-09
SK285415B6 (sk) 2007-01-04
SG98384A1 (en) 2003-09-19
KR20010020779A (ko) 2001-03-15
ID25704A (id) 2000-11-02
HUP0001632A3 (en) 2001-12-28
NL1015027C2 (nl) 2001-02-14
EP1173181B3 (en) 2015-03-25
DE60005940T2 (de) 2004-07-29
CA2307101C (en) 2003-01-28
GR20000100153A (el) 2000-12-29
NO322013B3 (no) 2017-11-06
EP1173181B1 (en) 2003-10-15
HUP0200912A2 (en) 2002-08-28
EP1173181A2 (en) 2002-01-23
PT1173181E (pt) 2004-02-27
NZ514882A (en) 2003-08-29
HUP0001632A2 (hu) 2001-05-28
ES2208317T3 (es) 2004-06-16
NO322013B1 (no) 2006-08-07
HU0001632D0 (en) 2000-06-28
UA72248C2 (en) 2005-02-15
SI1173181T1 (en) 2004-04-30
CN1196487C (zh) 2005-04-13
HK1041204A1 (en) 2002-07-05
HRP20010778A2 (en) 2002-12-31
ITMI20000922A1 (it) 2001-10-26
SE0001518L (sv) 2000-10-31
EA200000355A2 (ru) 2000-10-30
LT2000035A (en) 2000-11-27
FR2795646A1 (fr) 2001-01-05
TR200001132A3 (tr) 2001-01-22
NZ504163A (en) 2001-11-30
FR2795646B1 (fr) 2002-08-16
JP2000336043A (ja) 2000-12-05
ZA200002058B (en) 2000-11-02
EP1415652A2 (en) 2004-05-06
MXPA00003997A (es) 2002-03-08

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Legal Events

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MM9A Patent lapsed through non-payment of renewal fee