ID29578A - Turunan-turunan indeno-, nafto- dan benzosikloheptadihidrotiazol serta pembuatan dan penggunaannya sebagai obat-obatan anorektik - Google Patents
Turunan-turunan indeno-, nafto- dan benzosikloheptadihidrotiazol serta pembuatan dan penggunaannya sebagai obat-obatan anorektikInfo
- Publication number
- ID29578A ID29578A IDW20010719A ID20010719A ID29578A ID 29578 A ID29578 A ID 29578A ID W20010719 A IDW20010719 A ID W20010719A ID 20010719 A ID20010719 A ID 20010719A ID 29578 A ID29578 A ID 29578A
- Authority
- ID
- Indonesia
- Prior art keywords
- benzosicloheptihihidrotiazol
- nafto
- indeno
- derives
- manufacturing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19844547A DE19844547C2 (de) | 1998-09-29 | 1998-09-29 | Polycyclische Dihydrothiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID29578A true ID29578A (id) | 2001-09-06 |
Family
ID=7882588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW20010719A ID29578A (id) | 1998-09-29 | 1999-09-16 | Turunan-turunan indeno-, nafto- dan benzosikloheptadihidrotiazol serta pembuatan dan penggunaannya sebagai obat-obatan anorektik |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US6090833A (fr) |
| EP (1) | EP1119557B1 (fr) |
| JP (1) | JP3542078B2 (fr) |
| KR (1) | KR20010079952A (fr) |
| CN (1) | CN1143852C (fr) |
| AR (1) | AR020662A1 (fr) |
| AT (1) | ATE255569T1 (fr) |
| AU (1) | AU755158B2 (fr) |
| BR (1) | BR9915014A (fr) |
| CA (1) | CA2345359A1 (fr) |
| DE (2) | DE19844547C2 (fr) |
| DK (1) | DK1119557T3 (fr) |
| ES (1) | ES2212673T3 (fr) |
| HK (1) | HK1040080B (fr) |
| HU (1) | HUP0103504A3 (fr) |
| ID (1) | ID29578A (fr) |
| IL (1) | IL142096A0 (fr) |
| NO (1) | NO318388B1 (fr) |
| NZ (1) | NZ510399A (fr) |
| PL (1) | PL347072A1 (fr) |
| PT (1) | PT1119557E (fr) |
| RU (1) | RU2217427C2 (fr) |
| TR (1) | TR200100868T2 (fr) |
| WO (1) | WO2000018749A1 (fr) |
| ZA (1) | ZA200102446B (fr) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19908539A1 (de) * | 1999-02-26 | 2000-08-31 | Aventis Pharma Gmbh | Polycyclische 2-Amino-Dihydrothiazolsysteme, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| DE50003761D1 (de) * | 1999-11-05 | 2003-10-23 | Aventis Pharma Gmbh | Indeno-dihydrothiazol derivate, deren herstellung und deren verwendung als anorektische arzneimittel |
| AU781003B2 (en) | 2000-02-23 | 2005-04-28 | Aventis Pharma Deutschland Gmbh | 8,8A-dihydro-indeno(1,2-D)thiazole derivatives, substituted in position 8A, a method for their production and their use as medicaments, e.g. anorectic agents |
| DE10008274A1 (de) * | 2000-02-23 | 2001-08-30 | Aventis Pharma Gmbh | Substituierte 8,8a-Dihydro-3aH-indeno[1,2-d]thiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| SI1261593T1 (en) * | 2000-02-26 | 2004-02-29 | Aventis Pharma Deutschland Gmbh | 8,8a-dihydro-indeno 1,2-d)thiazole derivatives with a sulphonamido or sulphono substituent in the 2 position, a method for production thereof and use thereof as a medicament |
| DE10142722A1 (de) * | 2001-08-31 | 2003-03-27 | Aventis Pharma Gmbh | C2-substituierte Indan-1-one und ihre Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| DE10142663B4 (de) | 2001-08-31 | 2004-08-19 | Aventis Pharma Deutschland Gmbh | C2-Disubstituierte Indan-1-ol-Systeme |
| DE10142665B4 (de) * | 2001-08-31 | 2004-05-06 | Aventis Pharma Deutschland Gmbh | C2-Disubstituierte Indan-1-one und ihre Derivate |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| EP2305352A1 (fr) | 2004-04-02 | 2011-04-06 | Merck Sharp & Dohme Corp. | Inhibiteurs de la 5-alpha-reductase pour le traitement d'hommes aux troubles métaboliques et anthropométriques |
| CA2662084A1 (fr) | 2006-09-07 | 2008-03-13 | Nycomed Gmbh | Polytherapie contre le diabete sucre |
| JP5546451B2 (ja) | 2007-06-04 | 2014-07-09 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸の障害、炎症、癌および他の障害の処置に有用なグアニル酸シクラーゼのアゴニスト |
| SI2152663T1 (sl) | 2007-06-04 | 2014-08-29 | Ben Gurion University Of The Negev Research And Development Authority | Tri-arilne spojine in sestavki, ki vsebujejo isto |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| AU2009256157B2 (en) | 2008-06-04 | 2014-12-18 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| WO2010009319A2 (fr) | 2008-07-16 | 2010-01-21 | Synergy Pharmaceuticals Inc. | Agonistes de guanylate cyclase utiles pour le traitement de troubles gastro-intestinaux, inflammatoires, cancéreux et autres |
| WO2010047982A1 (fr) | 2008-10-22 | 2010-04-29 | Merck Sharp & Dohme Corp. | Nouveaux dérivés de benzimidazole cycliques utiles comme agents anti-diabétiques |
| JP5557845B2 (ja) | 2008-10-31 | 2014-07-23 | メルク・シャープ・アンド・ドーム・コーポレーション | 糖尿病用剤として有用な新規環状ベンゾイミダゾール誘導体 |
| EP2538784B1 (fr) | 2010-02-25 | 2015-09-09 | Merck Sharp & Dohme Corp. | Dérivés de benzimidazole utiles comme agents antidiabétiques |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| EP2677869B1 (fr) | 2011-02-25 | 2017-11-08 | Merck Sharp & Dohme Corp. | Nouveaux dérivés d'azabenzimidazole cyclique utiles en tant qu'agents antidiabétiques |
| CN103764672A (zh) | 2011-03-01 | 2014-04-30 | 辛纳吉制药公司 | 制备鸟苷酸环化酶c激动剂的方法 |
| RU2015106909A (ru) | 2012-08-02 | 2016-09-27 | Мерк Шарп И Доум Корп. | Антидиабетические трициклические соединения |
| CA2898482A1 (fr) | 2013-02-22 | 2014-08-28 | Linda L. Brockunier | Composes bicycliques antidiabetiques |
| WO2014139388A1 (fr) | 2013-03-14 | 2014-09-18 | Merck Sharp & Dohme Corp. | Nouveaux dérivés d'indole utiles en tant qu'agents antidiabétiques |
| WO2014151206A1 (fr) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonistes de la guanylate cyclase et leurs utilisations |
| CA2905435A1 (fr) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions utiles pour le traitement de troubles gastro-intestinaux |
| US10011637B2 (en) | 2013-06-05 | 2018-07-03 | Synergy Pharmaceuticals, Inc. | Ultra-pure agonists of guanylate cyclase C, method of making and using same |
| WO2015051496A1 (fr) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Composés tricycliques antidiabétiques |
| EP3065723B1 (fr) | 2013-11-05 | 2020-09-23 | Ben Gurion University of the Negev Research and Development Authority | Composés pour le traitement du diabète et des complications associées |
| EP3551176A4 (fr) | 2016-12-06 | 2020-06-24 | Merck Sharp & Dohme Corp. | Composés hétérocycliques antidiabétiques |
| EP3558298A4 (fr) | 2016-12-20 | 2020-08-05 | Merck Sharp & Dohme Corp. | Composés de spirochromane antidiabétiques |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2942003A (en) * | 1957-06-06 | 1960-06-21 | Gen Aniline & Film Corp | Process for preparing naphtho [1, 2-d]-thiazoles |
| DE2640358A1 (de) * | 1976-09-08 | 1978-03-16 | Hoechst Ag | Thiazolidinderivate und verfahren zu ihrer herstellung |
| JPH0514068A (ja) * | 1991-07-03 | 1993-01-22 | Shimada Phys & Chem Ind Co Ltd | 並列増幅部切換型高周波低雑音増幅装置 |
| JP3197602B2 (ja) * | 1992-02-17 | 2001-08-13 | 久光製薬株式会社 | チアゾール類縁化合物及び皮膚外用剤 |
| CN1143364A (zh) * | 1994-03-11 | 1997-02-19 | 山之内制药株式会社 | 5-ht3受体激动剂、新颖的噻唑衍生物及其中间体 |
| GB9517381D0 (en) * | 1995-08-24 | 1995-10-25 | Pharmacia Spa | Aryl and heteroaryl piperazine derivatives |
| TW416953B (en) * | 1996-09-25 | 2001-01-01 | Takeda Chemical Industries Ltd | Tricyclic compounds for eliciting a prostaglandin I2 receptor agonistic effect, their production and use |
-
1998
- 1998-09-29 DE DE19844547A patent/DE19844547C2/de not_active Expired - Fee Related
-
1999
- 1999-09-16 AT AT99969717T patent/ATE255569T1/de not_active IP Right Cessation
- 1999-09-16 KR KR1020017004010A patent/KR20010079952A/ko active IP Right Grant
- 1999-09-16 JP JP2000572209A patent/JP3542078B2/ja not_active Expired - Fee Related
- 1999-09-16 IL IL14209699A patent/IL142096A0/xx not_active IP Right Cessation
- 1999-09-16 TR TR2001/00868T patent/TR200100868T2/xx unknown
- 1999-09-16 DE DE59907961T patent/DE59907961D1/de not_active Expired - Lifetime
- 1999-09-16 HU HU0103504A patent/HUP0103504A3/hu unknown
- 1999-09-16 EP EP99969717A patent/EP1119557B1/fr not_active Expired - Lifetime
- 1999-09-16 PL PL99347072A patent/PL347072A1/xx not_active Application Discontinuation
- 1999-09-16 WO PCT/EP1999/006860 patent/WO2000018749A1/fr not_active Application Discontinuation
- 1999-09-16 ID IDW20010719A patent/ID29578A/id unknown
- 1999-09-16 BR BR9915014-0A patent/BR9915014A/pt not_active IP Right Cessation
- 1999-09-16 NZ NZ510399A patent/NZ510399A/en unknown
- 1999-09-16 PT PT99969717T patent/PT1119557E/pt unknown
- 1999-09-16 AU AU59787/99A patent/AU755158B2/en not_active Ceased
- 1999-09-16 RU RU2001111750/04A patent/RU2217427C2/ru not_active IP Right Cessation
- 1999-09-16 CA CA002345359A patent/CA2345359A1/fr not_active Abandoned
- 1999-09-16 ES ES99969717T patent/ES2212673T3/es not_active Expired - Lifetime
- 1999-09-16 CN CNB998114820A patent/CN1143852C/zh not_active Expired - Fee Related
- 1999-09-16 DK DK99969717T patent/DK1119557T3/da active
- 1999-09-27 AR ARP990104867A patent/AR020662A1/es unknown
- 1999-09-29 US US09/406,855 patent/US6090833A/en not_active Expired - Lifetime
-
2000
- 2000-06-27 US US09/604,666 patent/US6291486B1/en not_active Expired - Lifetime
-
2001
- 2001-03-23 NO NO20011503A patent/NO318388B1/no unknown
- 2001-03-26 ZA ZA200102446A patent/ZA200102446B/en unknown
-
2002
- 2002-03-01 HK HK02101580.2A patent/HK1040080B/zh not_active IP Right Cessation
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