ID28494A - INHIBITOR FAKTOR VIIa - Google Patents

INHIBITOR FAKTOR VIIa

Info

Publication number
ID28494A
ID28494A IDW20010598A ID20010598A ID28494A ID 28494 A ID28494 A ID 28494A ID W20010598 A IDW20010598 A ID W20010598A ID 20010598 A ID20010598 A ID 20010598A ID 28494 A ID28494 A ID 28494A
Authority
ID
Indonesia
Prior art keywords
factor viia
inhibitor factor
inhibitor
viia
factor
Prior art date
Application number
IDW20010598A
Other languages
English (en)
Indonesian (id)
Inventor
Safar Pavel
Safarova Alena
Wildgoose Peter
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of ID28494A publication Critical patent/ID28494A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IDW20010598A 1998-09-15 1999-09-02 INHIBITOR FAKTOR VIIa ID28494A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98117506A EP0987274A1 (en) 1998-09-15 1998-09-15 Factor VIIa Inhibitors

Publications (1)

Publication Number Publication Date
ID28494A true ID28494A (id) 2001-05-31

Family

ID=8232644

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20010598A ID28494A (id) 1998-09-15 1999-09-02 INHIBITOR FAKTOR VIIa

Country Status (25)

Country Link
US (1) US6287794B1 (no)
EP (2) EP0987274A1 (no)
JP (1) JP4537581B2 (no)
KR (1) KR100665490B1 (no)
CN (1) CN1203087C (no)
AR (1) AR027814A1 (no)
AT (1) ATE460424T1 (no)
AU (1) AU760580B2 (no)
BR (1) BR9913742A (no)
CA (1) CA2344048A1 (no)
CZ (1) CZ300249B6 (no)
DE (1) DE69942123D1 (no)
HK (1) HK1040253B (no)
HU (1) HUP0103851A3 (no)
ID (1) ID28494A (no)
IL (2) IL141415A0 (no)
MY (1) MY125150A (no)
NO (1) NO328523B1 (no)
NZ (1) NZ510509A (no)
PL (1) PL203227B1 (no)
RU (1) RU2223967C2 (no)
TR (1) TR200100766T2 (no)
TW (1) TW576839B (no)
WO (1) WO2000015658A1 (no)
ZA (1) ZA200101861B (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0987274A1 (en) * 1998-09-15 2000-03-22 Hoechst Marion Roussel Deutschland GmbH Factor VIIa Inhibitors
MXPA01007038A (es) * 1999-01-13 2002-07-30 Genentech Inc Inhibidores de proteasa serina.
EP1059302A1 (en) * 1999-06-08 2000-12-13 Aventis Pharma Deutschland GmbH Factor VIIa inhibitors
CA2388408A1 (en) * 1999-10-01 2001-04-12 Chugai Seiyaku Kabushiki Kaisha Prevention and treatment of diseases associated with blood coagulation
EP1095933A1 (en) 1999-10-30 2001-05-02 Aventis Pharma Deutschland GmbH Novel N-guanidinoalkylamides, their preparation, their use, and pharmaceutical preparations comprising them
EP1162194A1 (en) * 2000-06-06 2001-12-12 Aventis Pharma Deutschland GmbH Factor VIIa inhibitory (thio)urea derivatives, their preparation and their use
GB0014134D0 (en) * 2000-06-10 2000-08-02 Astrazeneca Ab Combination therapy
IL155202A0 (en) 2000-10-20 2003-11-23 Biocryst Pharm Inc Biaryl compounds as serine protease inhibitors
RU2003120070A (ru) 2000-12-06 2004-12-27 Авентис Фармаа Дойчланд Гмбх (De) Производные гуанидина и амидина в качестве ингибиторов фактора ха
JP4179878B2 (ja) 2001-02-02 2008-11-12 中外製薬株式会社 ペプチド誘導体
EP1270551A1 (en) 2001-06-26 2003-01-02 Aventis Pharma Deutschland GmbH Urea derivatives with antiproteolytic activity
EP1314733A1 (en) 2001-11-22 2003-05-28 Aventis Pharma Deutschland GmbH Indole-2-carboxamides as factor Xa inhibitors
WO2004043991A2 (en) * 2002-11-13 2004-05-27 Haematologic Technologies, Inc. Assay for tissue factor and factor viia
US7358268B2 (en) 2002-12-04 2008-04-15 Sanofi-Aventis Deutschland Gmbh Imidazole derivatives as factor Xa inhibitors
US7429581B2 (en) 2002-12-23 2008-09-30 Sanofi-Aventis Deutschland Gmbh Pyrazole-derivatives as factor Xa inhibitors
EP1479680A1 (en) 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH Azaindole derivatives as Factor Xa inhibitors
US7223780B2 (en) 2003-05-19 2007-05-29 Sanofi-Aventis Deutschland Gmbh Triazole-derivatives as blood clotting enzyme factor Xa inhibitors
US7741341B2 (en) 2003-05-19 2010-06-22 Sanofi-Aventis Deutschland Gmbh Benzimidazole-derivatives as factor Xa inhibitors
US7317027B2 (en) 2003-05-19 2008-01-08 Sanofi-Aventis Deutschland Gmbh Azaindole-derivatives as factor Xa inhibitors
EP1479675A1 (en) 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH Indazole-derivatives as factor Xa inhibitors
EP1479677A1 (en) * 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH New indole derivatives as factor xa inhibitors
AU2004249671A1 (en) 2003-05-20 2004-12-29 Genentech, Inc. Benzofuran inhibitors of factor VIIa
JP2007505160A (ja) 2003-05-20 2007-03-08 ジェネンテック・インコーポレーテッド 第ＶＩＩａ因子のアシルスルファミド阻害剤
EP1568698A1 (en) 2004-02-27 2005-08-31 Aventis Pharma Deutschland GmbH Pyrrole-derivatives as factor Xa inhibitors
WO2008107362A2 (en) * 2007-03-07 2008-09-12 Novo Nordisk Health Care Ag Stabiliser and inhibitors of factor vii
AU2008274655A1 (en) 2007-07-10 2009-01-15 Sanofi-Aventis Malonamide derivatives with antithrombotic activity
WO2009092758A1 (en) * 2008-01-23 2009-07-30 Novo Nordisk Health Care Ag New blood coagulation factor inhibitors
ES2675353T3 (es) 2011-02-04 2018-07-10 Octapharma Ag Procedimiento para inactivación/eliminación de factores de coagulación por precipitación
WO2020053773A1 (en) * 2018-09-11 2020-03-19 Anbition S.R.L. Peptides and medical uses thereof
EP3849582A1 (en) * 2018-09-11 2021-07-21 Anbition S.r.l. Peptides and medical uses thereof
AU2020300002A1 (en) 2019-07-01 2022-02-24 Tonix Pharma Limited Anti-CD154 antibodies and uses thereof
CN116963750A (zh) 2021-01-06 2023-10-27 通尼克斯制药有限公司 用经修饰的抗-cd154抗体诱导免疫耐受的方法
GB202209228D0 (en) * 2022-06-23 2022-08-10 Univ Strathclyde Modified amino acids and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023236A (en) * 1988-04-07 1991-06-11 Corvas, Inc. Factor VII/VIIA active site inhibitors
EP0391999A4 (en) * 1988-09-23 1991-03-13 Corvas, Inc. Peptidyl inhibitors of the initiation of coagulation
CA2008116C (en) * 1989-02-23 2001-11-20 Thomas Weller Glycine derivatives
US5190919A (en) * 1989-11-13 1993-03-02 Board Of Regents, The University Of Texas System Antihemostatic factor vii peptides
US5506134A (en) 1990-10-22 1996-04-09 Corvas International, Inc. Hypridoma and monoclonal antibody which inhibits blood coagulation tissue factor/factor VIIa complex
US5833982A (en) 1991-02-28 1998-11-10 Zymogenetics, Inc. Modified factor VII
US5788965A (en) 1991-02-28 1998-08-04 Novo Nordisk A/S Modified factor VII
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
JPH08511794A (ja) * 1993-06-18 1996-12-10 ハフスルント ニコムド エイ／エス ▲ｖｉｉ▼因子由来ペプチド
US5849510A (en) * 1994-04-26 1998-12-15 Selectide Corporation Factor Xa inhibitors
EP0758341B1 (en) * 1994-04-26 2004-03-24 Aventis Pharmaceuticals, Inc. FACTOR Xa INHIBITORS
US5837684A (en) * 1995-06-07 1998-11-17 Nycomed Imaging As Peptides
CA2244851A1 (en) * 1996-02-22 1997-08-28 Petrus Fredericus Wilhelmus Stouten M-amidino phenyl analogs as factor xa inhibitors
EP0987274A1 (en) * 1998-09-15 2000-03-22 Hoechst Marion Roussel Deutschland GmbH Factor VIIa Inhibitors

Also Published As

Publication number Publication date
WO2000015658A1 (en) 2000-03-23
PL346781A1 (en) 2002-02-25
JP2002524571A (ja) 2002-08-06
IL141415A (en) 2006-09-05
CZ300249B6 (cs) 2009-04-01
ATE460424T1 (de) 2010-03-15
EP1114061A1 (en) 2001-07-11
PL203227B1 (pl) 2009-09-30
HUP0103851A3 (en) 2002-05-28
JP4537581B2 (ja) 2010-09-01
BR9913742A (pt) 2001-06-05
CZ2001914A3 (en) 2001-06-13
NZ510509A (en) 2002-09-27
US6287794B1 (en) 2001-09-11
CA2344048A1 (en) 2000-03-23
EP1114061B1 (en) 2010-03-10
NO20011293D0 (no) 2001-03-14
ZA200101861B (en) 2001-10-22
EP0987274A1 (en) 2000-03-22
KR100665490B1 (ko) 2007-01-10
CN1318069A (zh) 2001-10-17
HK1040253A1 (en) 2002-05-31
KR20010075130A (ko) 2001-08-09
TR200100766T2 (tr) 2001-10-22
IL141415A0 (en) 2002-03-10
AU760580B2 (en) 2003-05-15
DE69942123D1 (de) 2010-04-22
AU5972399A (en) 2000-04-03
MY125150A (en) 2006-07-31
HUP0103851A2 (hu) 2002-04-29
TW576839B (en) 2004-02-21
HK1040253B (zh) 2005-09-02
RU2223967C2 (ru) 2004-02-20
NO20011293L (no) 2001-05-04
AR027814A1 (es) 2003-04-16
NO328523B1 (no) 2010-03-08
CN1203087C (zh) 2005-05-25

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