ID26031A - Turunan indol yang memiliki suatu aktivitas antiviral - Google Patents
Turunan indol yang memiliki suatu aktivitas antiviralInfo
- Publication number
- ID26031A ID26031A IDW20001898A ID20001898A ID26031A ID 26031 A ID26031 A ID 26031A ID W20001898 A IDW20001898 A ID W20001898A ID 20001898 A ID20001898 A ID 20001898A ID 26031 A ID26031 A ID 26031A
- Authority
- ID
- Indonesia
- Prior art keywords
- indol
- damages
- antiviral activity
- antiviral
- activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7820398 | 1998-03-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
ID26031A true ID26031A (id) | 2000-11-16 |
Family
ID=13655476
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDW20001898A ID26031A (id) | 1998-03-26 | 1999-03-26 | Turunan indol yang memiliki suatu aktivitas antiviral |
Country Status (17)
Country | Link |
---|---|
US (3) | US6333323B1 (xx) |
EP (1) | EP1069111A4 (xx) |
JP (1) | JP3794469B2 (xx) |
KR (1) | KR20010041705A (xx) |
CN (1) | CN1142909C (xx) |
AU (1) | AU752005B2 (xx) |
BR (1) | BR9909146A (xx) |
CA (1) | CA2326166A1 (xx) |
HU (1) | HUP0103460A3 (xx) |
ID (1) | ID26031A (xx) |
IL (1) | IL137974A0 (xx) |
NO (1) | NO317423B1 (xx) |
NZ (1) | NZ506435A (xx) |
PL (1) | PL343249A1 (xx) |
RU (1) | RU2217421C2 (xx) |
WO (1) | WO1999050245A1 (xx) |
ZA (1) | ZA200004047B (xx) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6142163A (en) * | 1996-03-29 | 2000-11-07 | Lam Research Corporation | Method and apparatus for pressure control in vacuum processors |
JP3794469B2 (ja) * | 1998-03-26 | 2006-07-05 | 塩野義製薬株式会社 | 抗ウイルス作用を有するインドール誘導体 |
AU757409B2 (en) * | 1998-06-03 | 2003-02-20 | Merck & Co., Inc. | Hiv integrase inhibitors |
EP1082121A4 (en) * | 1998-06-03 | 2003-02-05 | Merck & Co Inc | INTEGRASE HIV INHIBITORS |
WO2000039086A1 (fr) | 1998-12-25 | 2000-07-06 | Shionogi & Co., Ltd. | Composes heterocycliques aromatiques possedant des activites inhibitrices de l'integrase du vih |
US7294481B1 (en) * | 1999-01-05 | 2007-11-13 | Immunex Corporation | Method for producing recombinant proteins |
TR200202129T2 (tr) * | 1999-06-02 | 2003-03-21 | Shionogi & Co., Ltd. | Yeni ikameli propenon türevlerinin hazırlanması için prosesler. |
WO2001000578A1 (en) * | 1999-06-25 | 2001-01-04 | Merck & Co., Inc. | 1-(aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof |
ATE504572T1 (de) * | 1999-09-02 | 2011-04-15 | Shionogi & Co | Derivate von aromatische heterocyclen enthaltende integraseinhibitoren |
CZ20023940A3 (cs) * | 2000-06-13 | 2003-05-14 | Shionogi & Co., Ltd. | Lékařské směsi zahrnující propenonové deriváty |
WO2001095905A1 (en) * | 2000-06-14 | 2001-12-20 | Shionogi & Co., Ltd. | Inhibitor for enzyme having two divalent metal ions as active centers |
AU4322802A (en) * | 2000-11-16 | 2002-06-24 | Univ California | Marine actinomycete taxon for drug and fermentation product dicovery |
US7067539B2 (en) | 2001-02-08 | 2006-06-27 | Schering Corporation | Cannabinoid receptor ligands |
US7507767B2 (en) | 2001-02-08 | 2009-03-24 | Schering Corporation | Cannabinoid receptor ligands |
EP2033952B1 (en) | 2001-03-01 | 2012-08-29 | Shionogi&Co., Ltd. | Nitrogen-containing Heteroaryl compounds having HIV Integrase Inhibitory Activity |
ATE550320T1 (de) | 2001-08-10 | 2012-04-15 | Shionogi & Co | Antivirales mittel |
ITMI20012060A1 (it) * | 2001-10-05 | 2003-04-05 | Recordati Chem Pharm | Nuovi eterocilcli n-acilati |
RS51542B (sr) * | 2001-10-26 | 2011-06-30 | Istituto Di Ricerche Di Biologia Molecolare P.Angeletti Spa. | N-supstituisani hidroksipirimidinon karboksamidni inhibitori hiv integraze |
JP2005509032A (ja) | 2001-11-14 | 2005-04-07 | シェーリング コーポレイション | カンナビノイドレセプターリガンド |
WO2003049695A2 (en) * | 2001-12-07 | 2003-06-19 | The Government Of The United States Of America As Represented By The Secretary, Department Of Healthand Human Services | Compounds to treat hiv infection and aids |
US20030236277A1 (en) | 2002-02-14 | 2003-12-25 | Kadow John F. | Indole, azaindole and related heterocyclic pyrrolidine derivatives |
EP1539693B9 (en) | 2002-06-19 | 2008-10-08 | Schering Corporation | Cannabinoid receptor agonists |
US7176232B2 (en) | 2002-06-24 | 2007-02-13 | The Regents Of The University Of California | Salinosporamides and methods for use thereof |
PT1529044E (pt) * | 2002-08-02 | 2008-01-14 | Nereus Pharmaceuticals Inc | Desidrofenila-histinas e os seus análogos e a síntese de desidrofenila-histinas e os seus análogos |
US7919497B2 (en) * | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
US7935704B2 (en) * | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
JP3908248B2 (ja) | 2002-08-13 | 2007-04-25 | 塩野義製薬株式会社 | Hivインテグラーゼ阻害活性を有するヘテロ環化合物 |
WO2004034970A2 (en) * | 2002-09-27 | 2004-04-29 | Nereus Pharmaceuticals, Inc. | Macrocyclic lactams |
TW200505902A (en) | 2003-03-20 | 2005-02-16 | Schering Corp | Cannabinoid receptor ligands |
CA2532066C (en) * | 2003-06-20 | 2015-07-28 | Nereus Pharmaceuticals, Inc. | Methods of using [3.2.0] heterocyclic compounds and analogs thereof |
CN101791306A (zh) * | 2003-06-20 | 2010-08-04 | 加利福尼亚大学董事会 | 盐孢菌酰胺及其使用方法 |
JP2007519727A (ja) * | 2004-01-23 | 2007-07-19 | ネレアス ファーマシューティカルズ インコーポレイテッド | 抗菌薬として有用なビス−インドールピロール |
ATE482208T1 (de) | 2004-03-10 | 2010-10-15 | Us Of America Represented By T | Chinolin-4-one als inhibitoren der retroviralen integrase zur behandlung von hiv, aids und aids- related complex (arc) |
US7579371B2 (en) | 2004-04-30 | 2009-08-25 | Nereus Pharmaceuticals, Inc. | Methods of using [3.2.0] heterocyclic compounds and analogs thereof |
WO2006028525A2 (en) * | 2004-04-30 | 2006-03-16 | Nereus Pharmaceuticals, Inc. | [3.2.0] heterocyclic compounds and methods of using the same |
EP1799696B1 (en) | 2004-09-17 | 2008-11-12 | IDENIX Pharmaceuticals, Inc. | Phosphoindoles as hiv inhibitors |
US20060100432A1 (en) | 2004-11-09 | 2006-05-11 | Matiskella John D | Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione |
CN101155582B (zh) * | 2004-12-03 | 2013-04-24 | 达纳-法伯癌症研究公司 | 治疗肿瘤性疾病的组合物和方法 |
CN1316968C (zh) * | 2005-09-30 | 2007-05-23 | 青岛大学 | 吲哚-2,3-二酮在制备抗病毒或免疫增强剂药物中的应用 |
US7851476B2 (en) | 2005-12-14 | 2010-12-14 | Bristol-Myers Squibb Company | Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine |
JP5093096B2 (ja) * | 2006-03-02 | 2012-12-05 | アステラス製薬株式会社 | 17βHSDtype5阻害剤 |
TR200806911T1 (tr) * | 2006-03-17 | 2009-01-21 | Cipla Limited | 4-[1-(4-siyano fenil)-1-(1,2,4-triazol-1-il)metil] benzonitril ile 4[1-(1h-1,2,4-triazol-1-il)metilen benzonitril ara maddesinin sentezi. |
BRPI0709474A2 (pt) | 2006-04-06 | 2011-07-12 | Nerus Pharmaceuticals Inc | sìntese total de salinosporamida a e seus análogos |
US7807671B2 (en) | 2006-04-25 | 2010-10-05 | Bristol-Myers Squibb Company | Diketo-piperazine and piperidine derivatives as antiviral agents |
CA2664396A1 (en) * | 2006-09-29 | 2008-04-10 | Idenix Pharmaceuticals, Inc. | Enantiomerically pure phosphoindoles as hiv inhibitors |
US8129527B2 (en) * | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
US7824698B2 (en) * | 2007-02-02 | 2010-11-02 | Nereus Pharmaceuticals, Inc. | Lyophilized formulations of Salinosporamide A |
US8394816B2 (en) * | 2007-12-07 | 2013-03-12 | Irene Ghobrial | Methods of using [3.2.0] heterocyclic compounds and analogs thereof in treating Waldenstrom's Macroglobulinemia |
EP2234608A2 (en) | 2007-12-11 | 2010-10-06 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties |
CA2723465A1 (en) * | 2008-05-12 | 2009-11-19 | Nereus Pharmaceuticals, Inc. | Proteasome inhibitors |
WO2013123658A1 (en) | 2012-02-23 | 2013-08-29 | Empire Technology Development Llc | Azobenzene compounds with cholesterol group and their sunscreen compositions |
CN103420894A (zh) * | 2012-05-22 | 2013-12-04 | 中国科学院上海药物研究所 | 丁-2-烯-1,4-二酮类化合物及其制备方法和用途 |
CN117427077A (zh) | 2014-09-14 | 2024-01-23 | 阿瓦尼尔制药股份有限公司 | 用于治疗痴呆中的激越行为的包含右美沙芬化合物和奎尼丁的药物组合物 |
KR102623404B1 (ko) | 2015-03-06 | 2024-01-11 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 뇌 종양 치료 방법 |
EP3265090A4 (en) | 2015-03-06 | 2018-08-01 | Beyondspring Pharmaceuticals Inc. | Method of treating cancer associated with a ras mutation |
CA2980221C (en) * | 2015-03-31 | 2024-03-12 | The Royal Institution For The Advancement Of Learning/Mcgill University | Indole analogs as 5-oxo-ete receptor antagonists and method of use thereof |
EP3334726B1 (en) | 2015-07-13 | 2022-03-16 | Beyondspring Pharmaceuticals, Inc. | Plinabulin compositions |
MY192703A (en) | 2016-02-08 | 2022-09-02 | Beyondspring Pharmaceuticals Inc | Compositions containing tucaresol or its analogs |
MX2018015100A (es) | 2016-06-06 | 2019-09-04 | Beyondspring Pharmaceuticals Inc | Composicion y metodo para reducir la neutropenia. |
JP2020503363A (ja) | 2017-01-06 | 2020-01-30 | ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド | チューブリン結合化合物およびその治療的使用 |
WO2018144764A1 (en) | 2017-02-01 | 2018-08-09 | Beyondspring Pharmaceuticals, Inc. | Method of reducing neutropenia |
CN106995400B (zh) * | 2017-04-10 | 2019-08-06 | 湘潭大学 | 一种化合物及其盐及其合成方法 |
CN107226810B (zh) * | 2017-06-16 | 2020-04-28 | 郑州大学 | 吲哚衍生物及其制备方法和其抗流感病毒作用 |
KR20200112881A (ko) | 2018-01-24 | 2020-10-05 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 플리나불린의 투여를 통해 혈소판감소증을 감소시키는 조성물 및 방법 |
CN109810044B (zh) * | 2019-02-27 | 2022-05-03 | 贵州医科大学 | 一种具有hiv-1整合酶抑制活性的化合物及其制备和应用 |
WO2023115203A1 (en) * | 2021-12-20 | 2023-06-29 | Fairhaven Pharmaceuticals Inc. | Oxer1 antagonists and uses thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4377698A (en) * | 1976-01-22 | 1983-03-22 | Sterling Drug Inc. | 2,4 Bis(2-indolyl-3)-4-oxobutanoic acids |
WO1993005020A1 (en) * | 1991-09-06 | 1993-03-18 | Merck & Co., Inc. | Indoles as inhibitors of hiv reverse transcriptase |
US5475109A (en) | 1994-10-17 | 1995-12-12 | Merck & Co., Inc. | Dioxobutanoic acid derivatives as inhibitors of influenza endonuclease |
EP0820441B1 (en) * | 1995-04-10 | 2002-06-26 | Fujisawa Pharmaceutical Co., Ltd. | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS |
US5858738A (en) * | 1996-11-07 | 1999-01-12 | Merck & Co., Inc. | Ermophilane sesquiterpenoids as HIV intergrase inhibitors |
JP3794469B2 (ja) * | 1998-03-26 | 2006-07-05 | 塩野義製薬株式会社 | 抗ウイルス作用を有するインドール誘導体 |
EP1082121A4 (en) | 1998-06-03 | 2003-02-05 | Merck & Co Inc | INTEGRASE HIV INHIBITORS |
AU757409B2 (en) | 1998-06-03 | 2003-02-20 | Merck & Co., Inc. | Hiv integrase inhibitors |
CA2329134A1 (en) | 1998-06-03 | 1999-12-09 | David L. Clark | Hiv integrase inhibitors |
WO2001000578A1 (en) | 1999-06-25 | 2001-01-04 | Merck & Co., Inc. | 1-(aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof |
-
1999
- 1999-03-26 JP JP2000541150A patent/JP3794469B2/ja not_active Expired - Fee Related
- 1999-03-26 RU RU2000126474/04A patent/RU2217421C2/ru not_active IP Right Cessation
- 1999-03-26 CN CNB998044180A patent/CN1142909C/zh not_active Expired - Fee Related
- 1999-03-26 IL IL13797499A patent/IL137974A0/xx unknown
- 1999-03-26 WO PCT/JP1999/001547 patent/WO1999050245A1/ja not_active Application Discontinuation
- 1999-03-26 US US09/622,543 patent/US6333323B1/en not_active Expired - Fee Related
- 1999-03-26 EP EP99910719A patent/EP1069111A4/en not_active Withdrawn
- 1999-03-26 ID IDW20001898A patent/ID26031A/id unknown
- 1999-03-26 BR BR9909146-1A patent/BR9909146A/pt not_active IP Right Cessation
- 1999-03-26 HU HU0103460A patent/HUP0103460A3/hu unknown
- 1999-03-26 CA CA002326166A patent/CA2326166A1/en not_active Abandoned
- 1999-03-26 NZ NZ506435A patent/NZ506435A/xx unknown
- 1999-03-26 AU AU29581/99A patent/AU752005B2/en not_active Ceased
- 1999-03-26 PL PL99343249A patent/PL343249A1/xx unknown
- 1999-03-26 KR KR1020007009926A patent/KR20010041705A/ko not_active Application Discontinuation
-
2000
- 2000-08-08 ZA ZA200004047A patent/ZA200004047B/xx unknown
- 2000-09-25 NO NO20004787A patent/NO317423B1/no not_active IP Right Cessation
-
2001
- 2001-08-15 US US09/929,486 patent/US6506787B2/en not_active Expired - Fee Related
-
2002
- 2002-09-30 US US10/259,903 patent/US6716605B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6716605B2 (en) | 2004-04-06 |
CA2326166A1 (en) | 1999-10-07 |
WO1999050245A1 (fr) | 1999-10-07 |
US6506787B2 (en) | 2003-01-14 |
NO317423B1 (no) | 2004-10-25 |
NO20004787D0 (no) | 2000-09-25 |
NO20004787L (no) | 2000-11-27 |
JP3794469B2 (ja) | 2006-07-05 |
BR9909146A (pt) | 2000-12-05 |
AU2958199A (en) | 1999-10-18 |
US20030181499A1 (en) | 2003-09-25 |
CN1294580A (zh) | 2001-05-09 |
CN1142909C (zh) | 2004-03-24 |
HUP0103460A2 (hu) | 2002-01-28 |
NZ506435A (en) | 2002-08-28 |
AU752005B2 (en) | 2002-09-05 |
EP1069111A1 (en) | 2001-01-17 |
IL137974A0 (en) | 2001-10-31 |
US20020019434A1 (en) | 2002-02-14 |
EP1069111A4 (en) | 2001-06-06 |
US6333323B1 (en) | 2001-12-25 |
KR20010041705A (ko) | 2001-05-25 |
PL343249A1 (en) | 2001-07-30 |
HUP0103460A3 (en) | 2002-11-28 |
ZA200004047B (en) | 2001-04-25 |
RU2217421C2 (ru) | 2003-11-27 |
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