ID24957A - Turunan sulfonilamino yang menginhibisi metaloproteinase penurun matriks - Google Patents
Turunan sulfonilamino yang menginhibisi metaloproteinase penurun matriksInfo
- Publication number
- ID24957A ID24957A IDW20001501A ID20001501A ID24957A ID 24957 A ID24957 A ID 24957A ID W20001501 A IDW20001501 A ID W20001501A ID 20001501 A ID20001501 A ID 20001501A ID 24957 A ID24957 A ID 24957A
- Authority
- ID
- Indonesia
- Prior art keywords
- sulfonilamino
- metaloproteinase
- derivating
- initiating
- reducing matrix
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1881998A | 1998-02-04 | 1998-02-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID24957A true ID24957A (id) | 2000-08-31 |
Family
ID=21789936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW20001501A ID24957A (id) | 1998-02-04 | 1999-02-02 | Turunan sulfonilamino yang menginhibisi metaloproteinase penurun matriks |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6277987B1 (xx) |
| EP (2) | EP1053226A1 (xx) |
| JP (1) | JP4750272B2 (xx) |
| KR (1) | KR20010040698A (xx) |
| CN (1) | CN1195735C (xx) |
| AU (1) | AU747911B2 (xx) |
| BR (1) | BR9909322A (xx) |
| CA (1) | CA2318145C (xx) |
| HU (1) | HUP0101176A3 (xx) |
| ID (1) | ID24957A (xx) |
| IL (1) | IL137465A0 (xx) |
| NO (1) | NO317977B1 (xx) |
| NZ (1) | NZ505968A (xx) |
| PL (1) | PL342009A1 (xx) |
| RU (1) | RU2208609C2 (xx) |
| SK (1) | SK11692000A3 (xx) |
| TR (1) | TR200002224T2 (xx) |
| WO (1) | WO1999042443A1 (xx) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1304402A (zh) * | 1998-04-03 | 2001-07-18 | 三共株式会社 | 磺酰胺衍生物 |
| EP1165501A1 (en) * | 1999-03-03 | 2002-01-02 | The Procter & Gamble Company | Alkenyl- and alkynyl-containing metalloprotease inhibitors |
| CZ20013155A3 (cs) | 1999-03-03 | 2002-01-16 | The Procter & Gamble Company | Inhibitory metaloproteas |
| GB9918684D0 (en) | 1999-08-09 | 1999-10-13 | Novartis Ag | Organic compounds |
| EP1088815A1 (en) | 1999-09-28 | 2001-04-04 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonyl amino acid derivatives |
| AU7450300A (en) * | 1999-09-29 | 2001-04-30 | Sankyo Company Limited | Sulfonamide derivatives |
| NZ520657A (en) | 2000-03-21 | 2004-11-26 | Procter & Gamble | Heterocyclic side chain containing, N-substituted metalloprotease inhibitors |
| JP2003528082A (ja) | 2000-03-21 | 2003-09-24 | ザ プロクター アンド ギャンブル カンパニー | ニフッ化酪酸メタロプロテアーゼ阻害物質 |
| AU2001245863A1 (en) * | 2000-03-21 | 2001-10-03 | The Procter & Gamble Company | Heterocyclic side chain containing metalloprotease inhibitors |
| AU2001248701A1 (en) * | 2000-03-24 | 2001-10-03 | Methylgene, Inc. | Inhibitors of histone deacetylase |
| US6897237B2 (en) | 2000-04-28 | 2005-05-24 | Shionogi & Co. Ltd. | MMP-12 inhibitors |
| EP1174129A1 (en) * | 2000-07-17 | 2002-01-23 | Zenner, Hans Peter, Prof. Dr. med. | Use of a matrix-metalloprotease inhibitor for the treatment of cancer |
| GB0103303D0 (en) | 2001-02-09 | 2001-03-28 | Novartis Ag | Organic compounds |
| SE0100903D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
| SE0100902D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
| SE0103710D0 (sv) | 2001-11-07 | 2001-11-07 | Astrazeneca Ab | Compounds |
| ATE438618T1 (de) * | 2001-12-14 | 2009-08-15 | Exelixis Inc | Inhibitoren von humanem adam-10 |
| AU2003221160A1 (en) * | 2002-03-27 | 2003-10-08 | Shionogi And Co., Ltd. | Decomposition inhibitor for extracellular matrix of cartilage |
| AU2003239599B8 (en) | 2002-05-29 | 2008-08-14 | Merck Sharp & Dohme Corp. | Compounds useful in the treatment of anthrax and inhibiting lethal factor |
| SE0202539D0 (sv) | 2002-08-27 | 2002-08-27 | Astrazeneca Ab | Compounds |
| GB0221246D0 (en) * | 2002-09-13 | 2002-10-23 | Astrazeneca Ab | Compounds |
| CA2566191A1 (en) | 2004-05-11 | 2005-12-15 | Merck & Co., Inc. | Process for making n-sulfonated-amino acid derivatives |
| GB0412553D0 (en) | 2004-06-04 | 2004-07-07 | Univ Aberdeen | Therapeutic agents for the treatment of bone conditions |
| US7648992B2 (en) | 2004-07-05 | 2010-01-19 | Astrazeneca Ab | Hydantoin derivatives for the treatment of obstructive airway diseases |
| SE0401762D0 (sv) | 2004-07-05 | 2004-07-05 | Astrazeneca Ab | Novel compounds |
| JP2008512463A (ja) * | 2004-09-08 | 2008-04-24 | ボーイズ タウン ナショナル リサーチ ホスピタル | マトリックスメタロプロテイナーゼ−１２に関連する糸球体基底膜疾患の治療 |
| US20100003276A1 (en) * | 2004-12-07 | 2010-01-07 | Hermes Jeffery D | Methods for treating anthrax and inhibiting lethal factor |
| SE0403086D0 (sv) | 2004-12-17 | 2004-12-17 | Astrazeneca Ab | Compounds |
| SE0403085D0 (sv) | 2004-12-17 | 2004-12-17 | Astrazeneca Ab | Novel componds |
| US7576222B2 (en) * | 2004-12-28 | 2009-08-18 | Wyeth | Alkynyl-containing tryptophan derivative inhibitors of TACE/matrix metalloproteinase |
| US20100247512A1 (en) * | 2006-03-31 | 2010-09-30 | The Regents Of The University Of Michigan | Pericellular Collagenase Directs the 3-Dimensional Development of White Adipose Tissue |
| TW200831488A (en) * | 2006-11-29 | 2008-08-01 | Astrazeneca Ab | Novel compounds |
| EP1972617A1 (en) * | 2007-03-19 | 2008-09-24 | Bracco Imaging, S.P.A. | Compounds having aryl-sulphonamidic structure useful as metalloproteases inhibitors |
| GB0705400D0 (en) | 2007-03-21 | 2007-05-02 | Univ Aberdeen | Therapeutic compounds andm their use |
| WO2009118292A1 (en) | 2008-03-24 | 2009-10-01 | Novartis Ag | Arylsulfonamide-based matrix metalloprotease inhibitors |
| EP2149568A1 (en) | 2008-07-22 | 2010-02-03 | Bracco Imaging S.p.A | Aryl-sulphonamidic dimers as metalloproteases inhibitors |
| EP2147684A1 (en) | 2008-07-22 | 2010-01-27 | Bracco Imaging S.p.A | Diagnostic Agents Selective Against Metalloproteases |
| GB0817207D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | therapeutic apsac compounds and their use |
| GB0817208D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | Therapeutic apsap compounds and their use |
| US8557983B2 (en) | 2008-12-04 | 2013-10-15 | Abbvie Inc. | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
| UA108193C2 (uk) * | 2008-12-04 | 2015-04-10 | Апоптозіндукуючий засіб для лікування раку і імунних і аутоімунних захворювань | |
| US20100160322A1 (en) | 2008-12-04 | 2010-06-24 | Abbott Laboratories | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
| EP3666758A1 (en) * | 2008-12-05 | 2020-06-17 | AbbVie Inc. | Process for the preparation of a sulfonamide derivative |
| US8563735B2 (en) | 2008-12-05 | 2013-10-22 | Abbvie Inc. | Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases |
| US8586754B2 (en) | 2008-12-05 | 2013-11-19 | Abbvie Inc. | BCL-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases |
| ITTO20090648A1 (it) * | 2009-08-19 | 2011-02-20 | Istituto Naz Per La Ricerca Sul Cancro | Inibitori di adam17 atti a modulare il rilascio di alcam (cd166) solubile in cellule tumorali e loro uso nel trattamento terapeutico del carcinoma ovarico epiteliale (eoc) |
| US9023318B2 (en) | 2011-06-08 | 2015-05-05 | Siemens Medical Solutions Usa, Inc. | Compounds with matrix-metalloproteinase inhibitory activity and imaging agents thereof |
| GB201311361D0 (en) | 2013-06-26 | 2013-08-14 | Pimco 2664 Ltd | Compounds and their therapeutic use |
| LT3262028T (lt) | 2014-12-17 | 2022-01-10 | Pimco 2664 Limited | N-(4-hidroksi-4-metil-cikloheksil)-4-fenil-benzensulfonamido ir n-(-4-hidroksi-4-metil-cikloheksil)-4-(2-piridil)-benzensulfonamido junginiai ir jų terapinis panaudojimas |
| CN110483437B (zh) * | 2018-05-14 | 2022-12-06 | 嘉兴维眸生物科技有限公司 | 一种含五元环的化合物及其制备和应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1493665A1 (de) | 1964-07-16 | 1969-02-06 | Hoechst Ag | Verfahren zur Spaltung von aromatischen Carbonsaeureamiden |
| AU4267293A (en) | 1992-05-01 | 1993-11-29 | British Biotech Pharmaceuticals Limited | Use of MMP inhibitors |
| US5506242A (en) * | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
| US5552419A (en) | 1993-01-06 | 1996-09-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| US5646167A (en) * | 1993-01-06 | 1997-07-08 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamix acids |
| DK0766665T3 (da) | 1994-06-22 | 1999-12-06 | British Biotech Pharm | Metalloproteinaseinhibitorer |
| PL326700A1 (en) | 1995-11-17 | 1998-10-26 | Warner Lambert Co | Sulphonamide-based inhibitors of intercellular substance metaloproteinases |
| DK0874830T3 (da) | 1995-12-08 | 2003-04-22 | Agouron Pharma | Metalloproteinaseinhibitor, farmaceutisk præparat indeholdende denne og den farmaceutiske anvendelse samt en fremgangsmåde til fremstilling deraf |
| US5753653A (en) | 1995-12-08 | 1998-05-19 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
| SK282995B6 (sk) * | 1996-01-23 | 2003-01-09 | Shionogi And Co., Ltd. | Zlúčenina na inhibíciu metaloproteázy a prostriedok s jej obsahom |
| CA2253342A1 (en) * | 1996-05-17 | 1997-11-27 | Warner-Lambert Company | Biphenylsulfonamide matrix metalloproteinase inhibitors |
| EP0915086A4 (en) | 1996-05-24 | 2001-01-17 | Ono Pharmaceutical Co | PHENYLSULFONAMIDE DERIVATIVES |
| NZ334252A (en) | 1996-08-28 | 2000-11-24 | Procter & Gamble | Heterocyclic metalloprotease inhibitors |
| TR199900383T2 (xx) | 1996-08-28 | 1999-05-21 | The Procter & Gamble Company | 1,3-Diheterosiklik metaloproteaz inhibit�rleri. |
| BR9712792A (pt) | 1996-08-28 | 1999-12-14 | Procter & Gamble | Inibidores de metaloprotease bidentada. |
| ES2201318T3 (es) | 1996-08-28 | 2004-03-16 | THE PROCTER & GAMBLE COMPANY | Inhibidores de metaloproteasas de aminas ciclicas substituidas. |
| ES2225983T3 (es) | 1996-08-28 | 2005-03-16 | THE PROCTER & GAMBLE COMPANY | Inhibidores de metaloproteasas espirociclicos. |
| DK0923561T3 (da) | 1996-08-28 | 2003-02-24 | Procter & Gamble | Heterocykliske metalloproteaseinhibitorer |
| DK0946166T3 (da) * | 1996-12-17 | 2004-05-03 | Warner Lambert Co | Anvendelse af matrixmetalloproteinaseinhibitorer til fremme af sårheling |
| AU720615B2 (en) * | 1997-01-17 | 2000-06-08 | Pharmacia & Upjohn Company | Bis-sulfonomides hydroxamic acids as MMP inhibitors |
| US5985900A (en) * | 1997-04-01 | 1999-11-16 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
| CA2285372A1 (en) | 1997-04-01 | 1998-10-08 | Melwyn A. Abreo | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
| US5756545A (en) * | 1997-04-21 | 1998-05-26 | Warner-Lambert Company | Biphenysulfonamide matrix metal alloproteinase inhibitors |
| DE19719585A1 (de) | 1997-05-09 | 1998-11-12 | Hoechst Ag | Substituierte Diaminocarbonsäuren |
| DE19719428A1 (de) | 1997-05-12 | 1998-11-19 | Hoechst Ag | Substituierte Diaminocarbonsäuren |
| DE19719621A1 (de) * | 1997-05-09 | 1998-11-12 | Hoechst Ag | Sulfonylaminocarbonsäuren |
| WO1998050348A1 (en) | 1997-05-09 | 1998-11-12 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
| DK0877019T3 (da) | 1997-05-09 | 2002-04-08 | Hoechst Ag | Substituerede diaminocarboxylsyrer |
| NZ502274A (en) | 1997-07-22 | 2001-03-30 | Shionogi & Co | The use of a therapeutic or prophylactic agent containing a sulphonamide derivative for treating glomerulopathy |
| BR9810841A (pt) * | 1997-07-31 | 2001-07-10 | Procter & Gamble | Inibidores de metaloprotease alicìclicos |
-
1999
- 1999-02-02 CN CNB998027154A patent/CN1195735C/zh not_active Expired - Fee Related
- 1999-02-02 RU RU2000123166/04A patent/RU2208609C2/ru not_active IP Right Cessation
- 1999-02-02 EP EP99910174A patent/EP1053226A1/en not_active Ceased
- 1999-02-02 NZ NZ505968A patent/NZ505968A/xx unknown
- 1999-02-02 AU AU29235/99A patent/AU747911B2/en not_active Ceased
- 1999-02-02 IL IL13746599A patent/IL137465A0/xx unknown
- 1999-02-02 BR BR9909322-7A patent/BR9909322A/pt not_active IP Right Cessation
- 1999-02-02 TR TR2000/02224T patent/TR200002224T2/xx unknown
- 1999-02-02 SK SK1169-2000A patent/SK11692000A3/sk unknown
- 1999-02-02 EP EP07120827A patent/EP1918278A1/en not_active Withdrawn
- 1999-02-02 WO PCT/EP1999/000646 patent/WO1999042443A1/en not_active Application Discontinuation
- 1999-02-02 JP JP2000532395A patent/JP4750272B2/ja not_active Expired - Fee Related
- 1999-02-02 PL PL99342009A patent/PL342009A1/xx not_active Application Discontinuation
- 1999-02-02 CA CA002318145A patent/CA2318145C/en not_active Expired - Fee Related
- 1999-02-02 ID IDW20001501A patent/ID24957A/id unknown
- 1999-02-02 HU HU0101176A patent/HUP0101176A3/hu unknown
- 1999-02-02 KR KR1020007008576A patent/KR20010040698A/ko not_active Application Discontinuation
- 1999-02-03 US US09/243,854 patent/US6277987B1/en not_active Expired - Fee Related
-
2000
- 2000-07-11 NO NO20003565A patent/NO317977B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ505968A (en) | 2003-03-28 |
| PL342009A1 (en) | 2001-05-07 |
| CN1290250A (zh) | 2001-04-04 |
| JP4750272B2 (ja) | 2011-08-17 |
| NO20003565D0 (no) | 2000-07-11 |
| BR9909322A (pt) | 2000-12-05 |
| JP2002503720A (ja) | 2002-02-05 |
| AU747911B2 (en) | 2002-05-30 |
| SK11692000A3 (sk) | 2001-02-12 |
| CN1195735C (zh) | 2005-04-06 |
| EP1053226A1 (en) | 2000-11-22 |
| HUP0101176A3 (en) | 2002-06-28 |
| NO317977B1 (no) | 2005-01-17 |
| NO20003565L (no) | 2000-10-03 |
| AU2923599A (en) | 1999-09-06 |
| RU2208609C2 (ru) | 2003-07-20 |
| EP1918278A1 (en) | 2008-05-07 |
| WO1999042443A1 (en) | 1999-08-26 |
| TR200002224T2 (tr) | 2000-12-21 |
| KR20010040698A (ko) | 2001-05-15 |
| US6277987B1 (en) | 2001-08-21 |
| CA2318145A1 (en) | 1999-08-26 |
| IL137465A0 (en) | 2001-07-24 |
| HUP0101176A2 (hu) | 2001-09-28 |
| CA2318145C (en) | 2009-10-27 |
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