DE60114022D1 - Matrix metalloproteinase-inhibitoren - Google Patents

Matrix metalloproteinase-inhibitoren

Info

Publication number
DE60114022D1
DE60114022D1 DE60114022T DE60114022T DE60114022D1 DE 60114022 D1 DE60114022 D1 DE 60114022D1 DE 60114022 T DE60114022 T DE 60114022T DE 60114022 T DE60114022 T DE 60114022T DE 60114022 D1 DE60114022 D1 DE 60114022D1
Authority
DE
Germany
Prior art keywords
matrix metaloproteinase
metaloproteinase inhibitors
inhibitors
matrix
metaloproteinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60114022T
Other languages
English (en)
Other versions
DE60114022T2 (de
Inventor
Shahriar Mobashery
Rafael Fridman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wayne State University
Original Assignee
Wayne State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wayne State University filed Critical Wayne State University
Application granted granted Critical
Publication of DE60114022D1 publication Critical patent/DE60114022D1/de
Publication of DE60114022T2 publication Critical patent/DE60114022T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D331/00—Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
    • C07D331/02—Three-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms
DE60114022T 2000-05-30 2001-05-30 Matrix metalloproteinase-inhibitoren Expired - Lifetime DE60114022T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20787400P 2000-05-30 2000-05-30
US207874P 2000-05-30
US22685800P 2000-08-22 2000-08-22
US226858P 2000-08-22
PCT/US2001/017448 WO2001092244A1 (en) 2000-05-30 2001-05-30 Inhibitors of matrix metalloproteinases

Publications (2)

Publication Number Publication Date
DE60114022D1 true DE60114022D1 (de) 2006-02-23
DE60114022T2 DE60114022T2 (de) 2006-07-13

Family

ID=26902682

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60114022T Expired - Lifetime DE60114022T2 (de) 2000-05-30 2001-05-30 Matrix metalloproteinase-inhibitoren

Country Status (5)

Country Link
US (2) US6703415B2 (de)
EP (1) EP1309579B1 (de)
AU (1) AU2001265182A1 (de)
DE (1) DE60114022T2 (de)
WO (1) WO2001092244A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040105897A1 (en) * 2001-11-29 2004-06-03 Greystone Medical Group, Inc. Composition and method for the therapeutic modulation of matrix metalloproteinase
US20060178323A1 (en) * 2002-04-09 2006-08-10 Buxton Francis P Methods for the treatment of chronic pain and compositions therefor
UA79293C2 (en) * 2002-07-03 2007-06-11 Univ Wayne State 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents
GB0223249D0 (en) * 2002-10-08 2002-11-13 Amersham Plc Improved imaging agents
EP1592458A1 (de) * 2003-02-10 2005-11-09 GE Healthcare Limited Diagnostische bildgebungsmittel mitmmp-inhibtorischer aktivität
US8088737B2 (en) 2003-04-04 2012-01-03 Incyte Corporation Compositions, methods and kits relating to Her-2 cleavage
WO2004113502A2 (en) * 2003-06-20 2004-12-29 Avalon Pharmaceuticals, Inc. Identification of therapeutic agents using genetic fingerprinting
GB0326546D0 (en) * 2003-11-14 2003-12-17 Amersham Plc Inhibitor imaging agents
WO2006036928A2 (en) * 2004-09-27 2006-04-06 Wayne State University Inhibitors of matrix metalloproteinases to treat neurological disorders
US7928127B2 (en) * 2005-05-19 2011-04-19 Notre Dame University Inhibitors of matrix metallaproteinases
JP2012518001A (ja) * 2009-02-13 2012-08-09 インディアナ ユニバーシティ リサーチ アンド テクノロジー コーポレイション Ｍｍｐ２およびｍｍｐ９を阻害する化合物および方法
CN101559076B (zh) * 2009-05-27 2012-08-29 西北大学 抗肿瘤基质金属蛋白酶抑制剂
US8937151B2 (en) 2010-03-04 2015-01-20 University Of Notre Dame Du Lac Gelatinase inhibitors and prodrugs
US9604957B2 (en) 2014-02-20 2017-03-28 University Of Notre Dame Du Lac Selective matrix metalloproteinase inhibitors
US10357546B2 (en) * 2014-09-19 2019-07-23 University Of Notre Dame Du Lac Acceleration of diabetic wound healing

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2949474A (en) * 1956-02-06 1960-08-16 Rohm & Haas New unsaturated glycidyl ethers, polymers thereof and methods for producing them
US2965651A (en) * 1957-09-20 1960-12-20 Monsanto Chemicals Episulfide compounds
US3222326A (en) * 1962-01-29 1965-12-07 Du Pont Polymers of alkylene thioethers
US4797218A (en) * 1985-09-09 1989-01-10 Ciba-Geigy Corporation Stabilizer thiirane derivatives containing hindered phenol groups
US5288722A (en) * 1989-03-06 1994-02-22 Takeda Chemical Industries, Ltd. 6-amino-6-desoxyfumagillols, production and use thereof
GB2303850B (en) * 1994-06-22 1998-06-10 British Biotech Pharm Metalloproteinase inhibitors
US5739313A (en) * 1995-11-13 1998-04-14 Regents Of The University Of Minnesota Radionuclide labeling of vitamin B12 and coenzymes thereof
FR2757165B1 (fr) * 1996-12-12 1999-02-19 Inst Francais Du Petrole Ester de l'acide maleimidobenzoique
GB9702088D0 (en) * 1997-01-31 1997-03-19 Pharmacia & Upjohn Spa Matrix metalloproteinase inhibitors

Also Published As

Publication number Publication date
EP1309579B1 (de) 2005-10-12
DE60114022T2 (de) 2006-07-13
WO2001092244A1 (en) 2001-12-06
EP1309579A1 (de) 2003-05-14
US20020037916A1 (en) 2002-03-28
US20040127478A1 (en) 2004-07-01
US7144917B2 (en) 2006-12-05
AU2001265182A1 (en) 2001-12-11
US6703415B2 (en) 2004-03-09

Similar Documents

Publication Publication Date Title
AU3831901A (en) Matrix metalloproteinase inhibitors
ATE290000T1 (de) Muscarinagonisten
ATE252099T1 (de) Biarylcarboxamide
NO20032245L (no) Brönnbehandling
ATE312098T1 (de) Thiazinoxazolidinon
EE200200680A (et) Parendatud luminofoorid
ATA2932001A (de) Schneefräse
DE50114386D1 (de) Ng
DK1272488T3 (da) Tri-aryl-substitueret ethan-PDE4-inhibitorer
NO20030917L (no) Anvendelse
DE50100710D1 (de) Wischblatt
NO20030276L (no) Fremgangsmåte
DE60114022D1 (de) Matrix metalloproteinase-inhibitoren
ATE298751T1 (de) 7-oxopyridoryrimidine
ATE262530T1 (de) Indolochinazolinone
DE60022787D1 (de) Mehrwegventil
AR028336A1 (es) 4-hidroxi-tetrahidropiridonas fenilsubstituidas
ATE509008T1 (de) Sulfonylguanidine
DE60109229D1 (de) Tupfer
AR028061A1 (es) 2-enamino-cetonitrilos fenil-substituidos
AR027931A1 (es) Antitranspirantes
NO20024860L (no) Hårpleiesammensetninger
DE10052925B4 (de) Schaukelbett
ATE476423T1 (de) Benzoylpyridazine
HUP0302904A3 (en) Matrix metalloproteinase inhibitors

Legal Events

Date Code Title Description
8364 No opposition during term of opposition