DE60114022D1 - Matrix metalloproteinase-inhibitoren - Google Patents

Matrix metalloproteinase-inhibitoren

Info

Publication number
DE60114022D1
DE60114022D1 DE60114022T DE60114022T DE60114022D1 DE 60114022 D1 DE60114022 D1 DE 60114022D1 DE 60114022 T DE60114022 T DE 60114022T DE 60114022 T DE60114022 T DE 60114022T DE 60114022 D1 DE60114022 D1 DE 60114022D1
Authority
DE
Germany
Prior art keywords
matrix metaloproteinase
metaloproteinase inhibitors
inhibitors
matrix
metaloproteinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60114022T
Other languages
English (en)
Other versions
DE60114022T2 (de
Inventor
Shahriar Mobashery
Rafael Fridman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wayne State University
Original Assignee
Wayne State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wayne State University filed Critical Wayne State University
Publication of DE60114022D1 publication Critical patent/DE60114022D1/de
Application granted granted Critical
Publication of DE60114022T2 publication Critical patent/DE60114022T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D331/00—Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
    • C07D331/02—Three-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60114022T 2000-05-30 2001-05-30 Matrix metalloproteinase-inhibitoren Expired - Lifetime DE60114022T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20787400P 2000-05-30 2000-05-30
US207874P 2000-05-30
US22685800P 2000-08-22 2000-08-22
US226858P 2000-08-22
PCT/US2001/017448 WO2001092244A1 (en) 2000-05-30 2001-05-30 Inhibitors of matrix metalloproteinases

Publications (2)

Publication Number Publication Date
DE60114022D1 true DE60114022D1 (de) 2006-02-23
DE60114022T2 DE60114022T2 (de) 2006-07-13

Family

ID=26902682

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60114022T Expired - Lifetime DE60114022T2 (de) 2000-05-30 2001-05-30 Matrix metalloproteinase-inhibitoren

Country Status (5)

Country Link
US (2) US6703415B2 (de)
EP (1) EP1309579B1 (de)
AU (1) AU2001265182A1 (de)
DE (1) DE60114022T2 (de)
WO (1) WO2001092244A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040105897A1 (en) * 2001-11-29 2004-06-03 Greystone Medical Group, Inc. Composition and method for the therapeutic modulation of matrix metalloproteinase
JP2005526820A (ja) * 2002-04-09 2005-09-08 ノバルティス アクチエンゲゼルシャフト 慢性痛の処置のためのｍｍｐ７モジュレーターを含む組成物
UA79293C2 (en) * 2002-07-03 2007-06-11 Univ Wayne State 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents
GB0223249D0 (en) * 2002-10-08 2002-11-13 Amersham Plc Improved imaging agents
EP1592458A1 (de) * 2003-02-10 2005-11-09 GE Healthcare Limited Diagnostische bildgebungsmittel mitmmp-inhibtorischer aktivität
WO2004089294A2 (en) 2003-04-04 2004-10-21 Incyte Corporation Compositions, methods and kits relating to her-2 cleavage
WO2004113502A2 (en) * 2003-06-20 2004-12-29 Avalon Pharmaceuticals, Inc. Identification of therapeutic agents using genetic fingerprinting
GB0326546D0 (en) * 2003-11-14 2003-12-17 Amersham Plc Inhibitor imaging agents
WO2006036928A2 (en) * 2004-09-27 2006-04-06 Wayne State University Inhibitors of matrix metalloproteinases to treat neurological disorders
WO2006125208A1 (en) * 2005-05-19 2006-11-23 Wayne State University Inhibitors of matrix metalloproteinases
KR20110135938A (ko) * 2009-02-13 2011-12-20 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 매트릭스 메탈로프로테이나제(ｍｍｐ)2 및 ｍｍｐ9를 억제하기 위한 화합물 및 방법
CN101559076B (zh) * 2009-05-27 2012-08-29 西北大学 抗肿瘤基质金属蛋白酶抑制剂
US8937151B2 (en) 2010-03-04 2015-01-20 University Of Notre Dame Du Lac Gelatinase inhibitors and prodrugs
CN106536500B (zh) * 2014-02-20 2020-01-10 圣母大学 选择性基质金属蛋白酶抑制剂
WO2016044844A1 (en) * 2014-09-19 2016-03-24 University Of Notre Dame Du Lac Acceleration of diabetic wound healing

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2949474A (en) * 1956-02-06 1960-08-16 Rohm & Haas New unsaturated glycidyl ethers, polymers thereof and methods for producing them
US2965651A (en) * 1957-09-20 1960-12-20 Monsanto Chemicals Episulfide compounds
US3222326A (en) * 1962-01-29 1965-12-07 Du Pont Polymers of alkylene thioethers
US4797218A (en) * 1985-09-09 1989-01-10 Ciba-Geigy Corporation Stabilizer thiirane derivatives containing hindered phenol groups
US5288722A (en) * 1989-03-06 1994-02-22 Takeda Chemical Industries, Ltd. 6-amino-6-desoxyfumagillols, production and use thereof
JPH10507158A (ja) * 1994-06-22 1998-07-14 ブリティッシュ バイオテック ファーマシューティカルズ リミテッド 金属タンパク質分解酵素阻害剤
US5739313A (en) * 1995-11-13 1998-04-14 Regents Of The University Of Minnesota Radionuclide labeling of vitamin B12 and coenzymes thereof
FR2757165B1 (fr) * 1996-12-12 1999-02-19 Inst Francais Du Petrole Ester de l'acide maleimidobenzoique
GB9702088D0 (en) * 1997-01-31 1997-03-19 Pharmacia & Upjohn Spa Matrix metalloproteinase inhibitors

Also Published As

Publication number Publication date
AU2001265182A1 (en) 2001-12-11
US7144917B2 (en) 2006-12-05
US20040127478A1 (en) 2004-07-01
DE60114022T2 (de) 2006-07-13
EP1309579A1 (de) 2003-05-14
WO2001092244A1 (en) 2001-12-06
EP1309579B1 (de) 2005-10-12
US20020037916A1 (en) 2002-03-28
US6703415B2 (en) 2004-03-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition