ID21927A - Asam aminoalkanafosfonat tersubstitusi - Google Patents

Asam aminoalkanafosfonat tersubstitusi

Info

Publication number
ID21927A
ID21927A IDW990225A ID990225A ID21927A ID 21927 A ID21927 A ID 21927A ID W990225 A IDW990225 A ID W990225A ID 990225 A ID990225 A ID 990225A ID 21927 A ID21927 A ID 21927A
Authority
ID
Indonesia
Prior art keywords
pct
aliphatic
araliphatic
date apr
cycloaliphatic
Prior art date
Application number
IDW990225A
Other languages
English (en)
Indonesian (id)
Inventor
Pierre Acklin
Hans Allgeter
Yves Auberson
Silvio Ofner
Siem Jacob Veenstra
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ID21927A publication Critical patent/ID21927A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • C07F9/650994—Six-membered rings having the nitrogen atoms in the positions 1 and 4 condensed with carbocyclic rings or carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IDW990225A 1996-10-24 1997-10-22 Asam aminoalkanafosfonat tersubstitusi ID21927A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH262196 1996-10-24

Publications (1)

Publication Number Publication Date
ID21927A true ID21927A (id) 1999-08-12

Family

ID=4237878

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW990225A ID21927A (id) 1996-10-24 1997-10-22 Asam aminoalkanafosfonat tersubstitusi

Country Status (23)

Country Link
US (1) US6117873A (cs)
EP (1) EP0934326B1 (cs)
JP (1) JP3908790B2 (cs)
KR (1) KR20000052747A (cs)
CN (1) CN1092202C (cs)
AT (1) ATE325128T1 (cs)
AU (1) AU5188598A (cs)
BR (1) BR9713489A (cs)
CA (1) CA2269807C (cs)
CZ (1) CZ141399A3 (cs)
DE (1) DE59712642D1 (cs)
ES (1) ES2264171T3 (cs)
HU (1) HUP0000383A3 (cs)
ID (1) ID21927A (cs)
IL (1) IL129394A (cs)
NO (1) NO991902L (cs)
NZ (1) NZ334891A (cs)
PL (1) PL192286B1 (cs)
PT (1) PT934326E (cs)
RU (1) RU2181362C2 (cs)
SK (1) SK282548B6 (cs)
TR (1) TR199900897T2 (cs)
WO (1) WO1998017672A1 (cs)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2645199A (en) * 1998-11-18 2000-06-05 Viktor Veniaminovich Tets Dialkyl-1-aryl-1-(2,4-dioxo-5-amino-1,3-pyrimidin-5-yl)methy lphosphonates
US7205404B1 (en) 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
US20030114421A1 (en) * 2000-09-27 2003-06-19 Phan Hieu Trung Alpha-substituted beta-aminoethyl phosphonate derivatives
WO2002026752A1 (en) * 2000-09-27 2002-04-04 Ilex Oncology Research S.A. α-SUBSTITUTED β-AMINOETHYL PHOSPHONATES
GB0025849D0 (en) * 2000-10-23 2000-12-06 Smithkline Beecham Plc Novel compounds
US6492517B1 (en) * 2001-07-19 2002-12-10 Air Products And Chemicals, Inc. Method for preparing halomethyl heterocyclic compounds
TW200403066A (en) * 2002-04-30 2004-03-01 Novartis Ag New uses of substituted aminoalkanephosphonic acids
GB0307860D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Organic compounds
GB0310868D0 (en) * 2003-05-12 2003-06-18 Novartis Ag Organic compounds
GB0324542D0 (en) * 2003-10-21 2003-11-26 Novartis Ag Organic compounds
GB0324541D0 (en) * 2003-10-21 2003-11-26 Novartis Ag Organic compounds
GB0325175D0 (en) * 2003-10-28 2003-12-03 Novartis Ag Organic compounds
GB0325173D0 (en) * 2003-10-28 2003-12-03 Novartis Ag Organic compounds
GB0325172D0 (en) * 2003-10-28 2003-12-03 Novartis Ag Organic compounds
GB0325390D0 (en) * 2003-10-30 2003-12-03 Novartis Ag Organic compounds
EP2428516A1 (en) * 2003-11-19 2012-03-14 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
GB0405034D0 (en) * 2004-03-05 2004-04-07 Novartis Ag Organic compounds
AU2006232517A1 (en) * 2005-04-04 2006-10-12 Eisai R&D Management Co., Ltd. Dihydropyridine compounds and compositions for headaches
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
JP2008542301A (ja) 2005-05-26 2008-11-27 メタバシス・セラピューティクス・インコーポレイテッド 脂肪性肝疾患の処置のための甲状腺ホルモン様薬剤
AU2006249348B2 (en) * 2005-05-26 2012-05-24 Metabasis Therapeutics, Inc. Novel phosphinic acid-containing thyromimetics
US20080108603A1 (en) * 2006-10-19 2008-05-08 Eisenach James C Combination therapy for the treatment of pain
US20080108622A1 (en) * 2006-10-19 2008-05-08 Eisenach James C Combination therapy for the treatment of pain
GB0708507D0 (en) 2007-05-02 2007-06-13 Queen Mary & Westfield College Substituted phosphonates and their use
RU2010138648A (ru) 2008-02-20 2012-03-27 Актелион Фармасьютиклз Лтд (Ch) Азатрициклические соединения антибиотиков
WO2010014943A2 (en) 2008-08-01 2010-02-04 Bioxiness Pharmaceutics, Inc. Methionine analogs and methods of using same
WO2010041194A1 (en) 2008-10-07 2010-04-15 Actelion Pharmaceuticals Ltd Tricyclic oxazolidinone antibiotic compounds
EP2403860B1 (en) * 2009-03-04 2015-11-04 IDENIX Pharmaceuticals, Inc. Phosphothiophene and phosphothiazole as hcv polymerase inhibitors
AU2015217221A1 (en) 2014-02-13 2016-08-11 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
JP2017520545A (ja) 2014-07-02 2017-07-27 リガンド・ファーマシューティカルズ・インコーポレイテッド プロドラッグ化合物およびそれらの使用
CN110198719A (zh) 2016-11-21 2019-09-03 维京治疗公司 治疗糖原贮积病的方法
WO2018226604A1 (en) 2017-06-05 2018-12-13 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis
JP2021509907A (ja) 2018-01-09 2021-04-08 リガンド・ファーマシューティカルズ・インコーポレイテッド アセタール化合物およびその治療的使用
CA3094167A1 (en) 2018-03-22 2019-09-26 Viking Therapeutics, Inc. Crystalline forms and methods of producing crystalline forms of a compound
JP2022510691A (ja) 2018-12-05 2022-01-27 バイキング・セラピューティクス・インコーポレイテッド 線維症及び炎症の処置のための組成物
CN114409890A (zh) * 2022-02-28 2022-04-29 中国科学院长春应用化学研究所 一种氨基功能化的聚乙二醇衍生物及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK69790D0 (da) * 1990-03-16 1990-03-16 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling af anvendelse
DE69132340T2 (de) * 1990-11-06 2001-02-08 Yamanouchi Pharmaceutical Co., Ltd. Kondensiertes pyrazinderivat
US5118675A (en) * 1991-02-15 1992-06-02 American Home Products Corporation Quinoxaline phosphono-amino acids
US5480883A (en) * 1991-05-10 1996-01-02 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
WO1994000124A1 (en) * 1992-06-22 1994-01-06 Eckard Weber Glycine receptor antagonists and the use thereof
IL109397A0 (en) * 1993-04-28 1994-07-31 Schering Ag Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE4314592A1 (de) * 1993-04-28 1994-11-03 Schering Ag Benzo(f)chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
BR9609644A (pt) * 1995-07-10 1999-05-11 Novartis Ag Novo quiloxaina e ácidos quinoxalinailalcano-fosfônico
MY132385A (en) * 1995-08-31 2007-10-31 Novartis Ag 2,3-dioxo-1,2,3,4-tetrahydro-quinoxalinyl derivatives

Also Published As

Publication number Publication date
EP0934326B1 (de) 2006-05-03
SK52399A3 (en) 2000-04-10
JP3908790B2 (ja) 2007-04-25
NZ334891A (en) 2001-04-27
PL332775A1 (en) 1999-10-11
PL192286B1 (pl) 2006-09-29
CN1092202C (zh) 2002-10-09
SK282548B6 (sk) 2002-10-08
KR20000052747A (ko) 2000-08-25
PT934326E (pt) 2006-08-31
CA2269807C (en) 2007-04-10
ATE325128T1 (de) 2006-06-15
JP2001502681A (ja) 2001-02-27
AU5188598A (en) 1998-05-15
RU2181362C2 (ru) 2002-04-20
EP0934326A1 (de) 1999-08-11
HUP0000383A2 (hu) 2001-05-28
HUP0000383A3 (en) 2003-01-28
WO1998017672A1 (de) 1998-04-30
US6117873A (en) 2000-09-12
ES2264171T3 (es) 2006-12-16
NO991902D0 (no) 1999-04-21
CN1234037A (zh) 1999-11-03
CZ141399A3 (cs) 1999-07-14
IL129394A (en) 2002-05-23
BR9713489A (pt) 2000-02-29
TR199900897T2 (xx) 1999-07-21
NO991902L (no) 1999-06-21
IL129394A0 (en) 2000-02-17
CA2269807A1 (en) 1998-04-30
DE59712642D1 (de) 2006-06-08

Similar Documents

Publication Publication Date Title
ID21927A (id) Asam aminoalkanafosfonat tersubstitusi
DK0526488T3 (da) Benzylphosphonsyre-tyrosinkinaseinhibitorer
PT799209E (pt) Novas sulfonamidas
ATE168101T1 (de) Arylpyridazinone
ATE175114T1 (de) Pharmazeutische zusammensetzungen enthaltend einen opiat antagonist und calcium salze, ihre verwendung zur behandlung von endorphin- vermittelten krankheiten
ID22042A (id) Benzonaftiridin sebagai pengobatan cabang tenggorokan
HUP9701540A1 (hu) A gasztrointesztinális keringést elősegítő gyógyászati készítmény
ATE218350T1 (de) Verwendung von methanbisphosphonsäurederivaten zur behandlung von aufgelockerten prothesen
PT93213A (pt) Processo para a preparacao de derivados de n-fenilbenzamida com accao anti-ulcerosa e anti-alergica e de composicoes farmaceuticas que os contem
FR2712591B1 (fr) Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique.
AU5648496A (en) Pyrazolo-(1,5a)pyrimidines, their preparation and their use
TR199700206A2 (xx) Floralkil- ve floralkoksi ikame edilmi� heterosiklik bradikinin-antagonistleri, bunlar�n imal edilmesine mahsus usul ve bunlar�n kullan�lmalar�.
FR2549049B1 (fr) Nouvelles amidines, leur procede de preparation et leur application therapeutique
PT783495E (pt) Derivados de quinoxalina uteis em terapia
ATE163402T1 (de) Substituierte ortho- ethenylphenylessigsäurederivate
NO305519B1 (no) Benzo[f]kinoksalindionderivater og legemidler inneholdende disse
DK0673377T3 (da) Nye triazoloquinazoliner, fremstilling og anvendelse deraf
DE69310186D1 (de) 1,2-dihydro-2-oxo-3-aminochinoxalin derivate, ihre verwendung als heilmittel
DK0662081T3 (da) Ureidoacetamidderivater, deres fremstilling og lægemidler indeholdende disse derivater