ID21218A - Senyawa trisiklik piperidinil baru yang berguna sebagai penghambat transferase farnesil protein - Google Patents

Senyawa trisiklik piperidinil baru yang berguna sebagai penghambat transferase farnesil protein

Info

Publication number
ID21218A
ID21218A IDW990091A ID990091A ID21218A ID 21218 A ID21218 A ID 21218A ID W990091 A IDW990091 A ID W990091A ID 990091 A ID990091 A ID 990091A ID 21218 A ID21218 A ID 21218A
Authority
ID
Indonesia
Prior art keywords
protein transferase
pyricidic
reserve
new
cells
Prior art date
Application number
IDW990091A
Other languages
English (en)
Indonesian (id)
Inventor
Alan B Cooper
Alan K Mallams
Viyyodr M Girijavallabhan
Ronald J Doll
Arthur G Taveras
F George Njoroge
John J Baldwin
John C Reader
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ID21218A publication Critical patent/ID21218A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/59Hydrogenated pyridine rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IDW990091A 1996-09-13 1997-09-11 Senyawa trisiklik piperidinil baru yang berguna sebagai penghambat transferase farnesil protein ID21218A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71370396A 1996-09-13 1996-09-13

Publications (1)

Publication Number Publication Date
ID21218A true ID21218A (id) 1999-05-06

Family

ID=24867181

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW990091A ID21218A (id) 1996-09-13 1997-09-11 Senyawa trisiklik piperidinil baru yang berguna sebagai penghambat transferase farnesil protein

Country Status (19)

Country Link
EP (1) EP0931078B1 (hu)
JP (1) JP2001500507A (hu)
KR (1) KR20000036104A (hu)
CN (1) CN1237170A (hu)
AT (1) ATE345338T1 (hu)
AU (1) AU4337697A (hu)
BR (1) BR9712826A (hu)
CA (1) CA2265763A1 (hu)
CZ (1) CZ84199A3 (hu)
DE (1) DE69736950T2 (hu)
ES (1) ES2276435T3 (hu)
HU (1) HUP0000191A2 (hu)
ID (1) ID21218A (hu)
NO (1) NO991233L (hu)
NZ (1) NZ334452A (hu)
PL (1) PL332241A1 (hu)
SK (1) SK33099A3 (hu)
TR (1) TR199901274T2 (hu)
WO (1) WO1998011098A1 (hu)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509346B2 (en) 1998-01-21 2003-01-21 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6613905B1 (en) 1998-01-21 2003-09-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
ATE309249T1 (de) 1998-01-21 2005-11-15 Millennium Pharm Inc Chemokin rezeptor antagonisten und verwndung
US6433165B1 (en) 1998-01-21 2002-08-13 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6288083B1 (en) 1998-09-04 2001-09-11 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7271176B2 (en) 1998-09-04 2007-09-18 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use thereof
US6503926B2 (en) 1998-09-04 2003-01-07 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
AU2002236813A1 (en) 2001-01-22 2002-07-30 Schering Corporation Treatment of malaria with farnesyl protein transferase inhibitors
AU2002257114A1 (en) * 2001-04-06 2002-10-21 Schering Corporation Treatment of malaria with farsenyl protein transferase inhibitors
US7541365B2 (en) 2001-11-21 2009-06-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
TWI291467B (en) 2002-11-13 2007-12-21 Millennium Pharm Inc CCR1 antagonists and methods of use therefor
NZ551603A (en) * 2004-06-24 2010-11-26 Incyte Corp N-substituted piperidines and their use as pharmaceuticals
BRPI0717513A2 (pt) * 2006-10-06 2013-11-19 Bausch & Lomb Processo para preparar um composto, enantiômero isolado de uma fluoroquinolona, uso do enantiômero isolado, e, composição oftálmica
US7632944B2 (en) * 2007-01-24 2009-12-15 Bausch & Lomb Incorporated Quinolone carboxylic acids, derivatives thereof, and methods of making and using same
US20110136790A1 (en) * 2008-07-23 2011-06-09 De Lera Ruiz Manuel Tricyclic Heterocyclic Derivatives and Methods of Use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593417A (en) * 1976-12-22 1981-07-15 Squibb & Sons Inc Carbocyclic-fused pyrazolopyridine derivatives
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
IE68935B1 (en) * 1990-06-22 1996-07-24 Schering Corp Bis-benzo or benzopyrido cyclohepta piperidene piperidylidene and piperazine compounds compositions and methods of use
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
CA2174105C (en) * 1993-10-15 2002-02-12 W. Robert Bishop Tricyclic carbamate compounds useful for inhibition of g-protein function and for treatment of proliferative diseases

Also Published As

Publication number Publication date
ATE345338T1 (de) 2006-12-15
WO1998011098A1 (en) 1998-03-19
DE69736950T2 (de) 2007-09-20
ES2276435T3 (es) 2007-06-16
BR9712826A (pt) 1999-11-16
KR20000036104A (ko) 2000-06-26
NZ334452A (en) 2000-09-29
AU4337697A (en) 1998-04-02
EP0931078A1 (en) 1999-07-28
NO991233L (no) 1999-05-12
NO991233D0 (no) 1999-03-12
CZ84199A3 (cs) 1999-11-17
SK33099A3 (en) 2000-05-16
EP0931078B1 (en) 2006-11-15
HUP0000191A2 (hu) 2001-04-28
CN1237170A (zh) 1999-12-01
CA2265763A1 (en) 1998-03-19
TR199901274T2 (xx) 1999-10-21
PL332241A1 (en) 1999-08-30
JP2001500507A (ja) 2001-01-16
DE69736950D1 (de) 2006-12-28

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