AU2002257114A1 - Treatment of malaria with farsenyl protein transferase inhibitors - Google Patents

Treatment of malaria with farsenyl protein transferase inhibitors

Info

Publication number
AU2002257114A1
AU2002257114A1 AU2002257114A AU2002257114A AU2002257114A1 AU 2002257114 A1 AU2002257114 A1 AU 2002257114A1 AU 2002257114 A AU2002257114 A AU 2002257114A AU 2002257114 A AU2002257114 A AU 2002257114A AU 2002257114 A1 AU2002257114 A1 AU 2002257114A1
Authority
AU
Australia
Prior art keywords
farsenyl
malaria
treatment
protein transferase
transferase inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002257114A
Inventor
Viyyoor M. Girijavallabhan
Corey O. Strickland
Patricia C. Weber
William T. Windsor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AU2002257114A1 publication Critical patent/AU2002257114A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002257114A 2001-04-06 2002-04-04 Treatment of malaria with farsenyl protein transferase inhibitors Abandoned AU2002257114A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US28209201P 2001-04-06 2001-04-06
US60/282,092 2001-04-06
US28310701P 2001-04-11 2001-04-11
US60/283,107 2001-04-11
PCT/US2002/010698 WO2002080895A2 (en) 2001-04-06 2002-04-04 Treatment of malaria with farsenyl protein transferase inhibitors

Publications (1)

Publication Number Publication Date
AU2002257114A1 true AU2002257114A1 (en) 2002-10-21

Family

ID=26961242

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002257114A Abandoned AU2002257114A1 (en) 2001-04-06 2002-04-04 Treatment of malaria with farsenyl protein transferase inhibitors

Country Status (2)

Country Link
AU (1) AU2002257114A1 (en)
WO (1) WO2002080895A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060106060A1 (en) * 2004-03-18 2006-05-18 The Brigham And Women's Hospital, Inc. Methods for the treatment of synucleinopathies (Lansbury)
EP1838324A2 (en) * 2004-12-13 2007-10-03 Schering Corporation Novel farnesyl protein transferase inhibitors and their use to treat cancer
EP1833481A1 (en) * 2004-12-14 2007-09-19 Schering Corporation Farnesyl protein transferase inhibitors and methods for treating proliferative diseases
DE102005017116A1 (en) * 2005-04-13 2006-10-26 Novartis Ag Inhibitors of Inhibitors of Apoptosis Proteins (IAP)
EP2397477B1 (en) 2007-01-16 2014-03-05 Purdue Pharma LP Heterocyclic-substituted piperidine compounds and the uses thereof
CA2685860A1 (en) 2007-05-10 2008-11-20 Amr Technology, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
ES2920605T3 (en) 2007-08-31 2022-08-05 Purdue Pharma Lp Piperidine Intermediates
BR122019007990B1 (en) 2013-11-18 2021-05-04 Forma Therapeutics, Inc COMPOUND, AND, PHARMACEUTICAL COMPOSITION
US9422281B2 (en) 2013-11-18 2016-08-23 Forma Therapeutics, Inc. Benzopiperazine compositions as BET bromodomain inhibitors
CN118556044A (en) * 2022-01-29 2024-08-27 江苏恒瑞医药股份有限公司 Fused heterocyclic compound, preparation method thereof and application thereof in medicine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5021426A (en) * 1990-02-26 1991-06-04 Merck & Co., Inc. Method of traeting malaria with cyproheptadine derivatives
JP3264388B2 (en) * 1992-12-28 2002-03-11 ポーラ化成工業株式会社 Drugs against drug-resistant pathogenic microorganisms
US5874442A (en) * 1995-12-22 1999-02-23 Schering-Plough Corporation Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative disease
NZ334452A (en) * 1996-09-13 2000-09-29 Schering Corp Tricyclic piperidinyl compounds useful as inhibitors of farnesyl-protein transferase (FTase)
ZA985203B (en) * 1997-06-17 1999-01-05 Schering Corp Compounds useful for inhibition of farnesyl protein transferase
NZ509372A (en) * 1998-08-27 2003-08-29 Pfizer Prod Inc Substituted quinolin-2-one derivatives, pharmaceuticals thereof and their use for treating abnormal cell growth (e.g. cancer)
ATE289602T1 (en) * 1998-08-27 2005-03-15 Pfizer Prod Inc QUINOLIN-2-ONE DERIVATIVES USABLE AS ANTI-CANCER AGENT
AR021718A1 (en) * 1998-12-18 2002-07-31 Schering Corp PROTEINA FARNESILO TRANSFER INHIBITORS.
KR20010081115A (en) * 1998-12-18 2001-08-27 둘락 노먼 씨. Farnesyl protein transferase inhibitors
AU2002236813A1 (en) * 2001-01-22 2002-07-30 Schering Corporation Treatment of malaria with farnesyl protein transferase inhibitors

Also Published As

Publication number Publication date
WO2002080895A3 (en) 2003-11-06
WO2002080895A2 (en) 2002-10-17

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase