ID21196A - Proses pembuatan yang diperbaiki dari asam 4-siano-4-(indazol tersubstitusi) sikloheksana-karboksilat yang berguna sebagai inhibitor pde4 - Google Patents

Proses pembuatan yang diperbaiki dari asam 4-siano-4-(indazol tersubstitusi) sikloheksana-karboksilat yang berguna sebagai inhibitor pde4

Info

Publication number
ID21196A
ID21196A IDP981436A ID981436A ID21196A ID 21196 A ID21196 A ID 21196A ID P981436 A IDP981436 A ID P981436A ID 981436 A ID981436 A ID 981436A ID 21196 A ID21196 A ID 21196A
Authority
ID
Indonesia
Prior art keywords
cyclohexs
carboxicate
siano
acid
making process
Prior art date
Application number
IDP981436A
Other languages
English (en)
Indonesian (id)
Inventor
Stephane Caron
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ID21196A publication Critical patent/ID21196A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/86—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IDP981436A 1997-11-04 1998-11-02 Proses pembuatan yang diperbaiki dari asam 4-siano-4-(indazol tersubstitusi) sikloheksana-karboksilat yang berguna sebagai inhibitor pde4 ID21196A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6421197P 1997-11-04 1997-11-04

Publications (1)

Publication Number Publication Date
ID21196A true ID21196A (id) 1999-05-06

Family

ID=22054312

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP981436A ID21196A (id) 1997-11-04 1998-11-02 Proses pembuatan yang diperbaiki dari asam 4-siano-4-(indazol tersubstitusi) sikloheksana-karboksilat yang berguna sebagai inhibitor pde4

Country Status (17)

Country Link
EP (1) EP0915089A3 (ko)
JP (1) JP3029424B2 (ko)
KR (1) KR100318693B1 (ko)
CN (1) CN1109673C (ko)
AR (1) AR015479A1 (ko)
AU (1) AU736071B2 (ko)
BR (1) BR9804754A (ko)
CA (1) CA2252344C (ko)
HK (1) HK1018774A1 (ko)
HU (1) HUP9802526A3 (ko)
ID (1) ID21196A (ko)
IL (1) IL126745A (ko)
PL (1) PL329494A1 (ko)
RU (1) RU2190606C2 (ko)
TR (1) TR199802203A2 (ko)
TW (1) TW577877B (ko)
ZA (1) ZA9810040B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000198734A (ja) * 1998-12-30 2000-07-18 Pfizer Inc 胃運動性減弱および関連疾患の治療のための運動性増強薬
US7601847B2 (en) 2004-10-26 2009-10-13 Wyeth Preparation and purification of 4-(indazol-3-yl)phenols

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU198036B (en) * 1983-08-22 1989-07-28 Hoechst Roussel Pharma Process for production of derivatives of 3-piperidil-/1h/-indasole and medical preparatives containing them
JPH061350B2 (ja) * 1985-07-26 1994-01-05 コニカ株式会社 ハロゲン化銀写真感光材料
EP0302423A3 (en) * 1987-08-07 1991-01-09 Hoechst-Roussel Pharmaceuticals Incorporated 1-phenyl-3-(1-piperazinyl)-1h-indazoles, a process and intermediates for their preparation, and the use thereof as medicaments
GB9305623D0 (en) * 1993-03-18 1993-05-05 Merck Sharp & Dohme Therapeutic agents
WO1996012720A1 (en) * 1994-10-20 1996-05-02 Pfizer Inc. Bicyclic tetrahydro pyrazolopyridines and their use as medicaments
AP1147A (en) * 1996-05-03 2003-02-25 Pfizer Substituted indazole derivatives and related compounds.
CA2309175A1 (en) * 1997-11-04 1999-05-14 Pfizer Products Inc. Therapeutically active compounds based on indazole bioisostere replacement of catechol in pde4 inhibitors

Also Published As

Publication number Publication date
TR199802203A2 (xx) 2001-05-21
CA2252344C (en) 2002-12-10
ZA9810040B (en) 2000-05-03
HUP9802526A3 (en) 2004-07-28
HK1018774A1 (en) 2000-01-07
BR9804754A (pt) 2000-04-11
JPH11228543A (ja) 1999-08-24
CA2252344A1 (en) 1999-05-04
CN1109673C (zh) 2003-05-28
IL126745A (en) 2003-09-17
AU9238598A (en) 1999-05-27
AR015479A1 (es) 2001-05-02
AU736071B2 (en) 2001-07-26
HUP9802526A2 (hu) 1999-06-28
JP3029424B2 (ja) 2000-04-04
PL329494A1 (en) 1999-05-10
KR100318693B1 (ko) 2002-08-22
EP0915089A2 (en) 1999-05-12
CN1221739A (zh) 1999-07-07
EP0915089A3 (en) 2004-02-25
IL126745A0 (en) 1999-08-17
RU2190606C2 (ru) 2002-10-10
HU9802526D0 (en) 1998-12-28
KR19990044975A (ko) 1999-06-25
TW577877B (en) 2004-03-01

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