ID18010A - Oligosakarida termodifikasi - Google Patents

Oligosakarida termodifikasi

Info

Publication number
ID18010A
ID18010A IDP972766A ID972766A ID18010A ID 18010 A ID18010 A ID 18010A ID P972766 A IDP972766 A ID P972766A ID 972766 A ID972766 A ID 972766A ID 18010 A ID18010 A ID 18010A
Authority
ID
Indonesia
Prior art keywords
oligosakarida
modified
modified oligosakarida
Prior art date
Application number
IDP972766A
Other languages
English (en)
Indonesian (id)
Inventor
Gebfard Dr Thoma
Rolf Dr Banteli
Willy Dr Kinzy
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ID18010A publication Critical patent/ID18010A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IDP972766A 1996-08-08 1997-08-08 Oligosakarida termodifikasi ID18010A (id)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96810527 1996-08-08
EP96810526 1996-08-08
EP96810636 1996-09-26

Publications (1)

Publication Number Publication Date
ID18010A true ID18010A (id) 1998-02-19

Family

ID=27237868

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP972766A ID18010A (id) 1996-08-08 1997-08-08 Oligosakarida termodifikasi

Country Status (19)

Country Link
EP (1) EP0920437A1 (fr)
JP (1) JP2000516224A (fr)
KR (1) KR20000029862A (fr)
CN (1) CN1227563A (fr)
AR (1) AR008283A1 (fr)
AU (1) AU720381B2 (fr)
BR (1) BR9711117A (fr)
CA (1) CA2260854A1 (fr)
CO (1) CO4900075A1 (fr)
CZ (1) CZ39099A3 (fr)
ID (1) ID18010A (fr)
IL (1) IL127908A0 (fr)
NO (1) NO990497L (fr)
NZ (1) NZ334048A (fr)
PE (1) PE99298A1 (fr)
PL (1) PL331286A1 (fr)
SK (1) SK15699A3 (fr)
TR (1) TR199900245T2 (fr)
WO (1) WO1998006730A1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5888984A (en) * 1994-05-12 1999-03-30 Dermal Research Laboratories, Inc. Pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same
EP1165097B1 (fr) * 1999-02-01 2007-05-02 Dermal Research Laboratories, Inc. Composition pharmaceutique d'hydrates de carbone complexes l'utilisation de celle-ci
US7879824B2 (en) 2001-07-31 2011-02-01 Dermal Research Laboratories, Inc. Methods of preventing or treating diseases and conditions using complex carbohydrates
US20040096396A1 (en) * 2002-07-03 2004-05-20 Glycomimetics, Inc. Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis
DE60329511D1 (de) 2002-10-11 2009-11-12 Astellas Pharma Europ B V Verbindungen auf glukosebasis mit affinitüt für p-selektin
JP2007524658A (ja) * 2003-11-19 2007-08-30 グリコミメティクス， インコーポレイテッド Ｅ−およびｐ−セレクチンの両方のための糖模倣物アンタゴニスト
WO2006127906A1 (fr) * 2005-05-25 2006-11-30 Glycomimetics, Inc. Composes heterobifonctionnels pour l’inhibition de la selectine
WO2007028050A1 (fr) 2005-09-02 2007-03-08 Glycomimetics, Inc. Inhibiteurs de pan-selectine heterobifonctionnels
AU2008216794A1 (en) * 2007-02-09 2008-08-21 Glycomimetics, Inc. Methods of use of glycomimetics with replacements for hexoses and N-acetyl hexosamines
WO2009073911A1 (fr) 2007-12-10 2009-06-18 Mater Medical Research Institute Traitement et prophylaxie
WO2009126556A1 (fr) 2008-04-08 2009-10-15 Glycomimetics, Inc. Inhibiteur de pan-sélectine avec activité pharmacocinétique améliorée
WO2012037034A1 (fr) 2010-09-14 2012-03-22 Glycomimetics, Inc. Antagonistes de l'e-sélectine
CN104039805B (zh) 2011-12-22 2016-11-16 糖模拟物有限公司 E-选择蛋白拮抗剂化合物、组合物及使用方法
EP2928476B1 (fr) 2012-12-07 2018-02-14 GlycoMimetics, Inc. Composés, compositions et procédés utilisant des antagonistes d'e-sélectine pour la mobilisation de cellules hématopoïétiques
WO2016089872A1 (fr) 2014-12-03 2016-06-09 Glycomimetics, Inc. Inhibiteurs hétérobifonctionnels des e-sélectines et des récepteurs aux chimiokines cxcr4
CA3009836A1 (fr) 2016-01-22 2017-07-27 Glycomimetics, Inc. Inhibiteurs glycomimetiques des lectines pa-il et pa-iil
WO2017151708A1 (fr) 2016-03-02 2017-09-08 Glycomimetics, Inc. Méthodes pour le traitement et/ou à la prévention de maladies cardiovasculaires par inhibition de la sélectine e
WO2018031445A1 (fr) 2016-08-08 2018-02-15 Glycomimetics, Inc. Combinaison d'inhibiteurs des points de contrôle des lymphocytes t avec des inhibiteurs de e-sélectine ou de cxcr4, ou avec des inhibiteurs hétérobifonctionnels de e-sélectine et de cxcr4
BR112019006642A2 (pt) 2016-10-07 2019-07-02 Glycomimetics Inc antagonistas multiméricos de e-selectina altamente potentes
CA3054605A1 (fr) 2017-03-15 2018-09-20 Glycomimetics, Inc. Derives de galactopyranosyle-cyclohexyle utilises en tant qu'antagonistes d'e-selectine
US11712446B2 (en) 2017-11-30 2023-08-01 Glycomimetics, Inc. Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
EP3732186A1 (fr) 2017-12-29 2020-11-04 GlycoMimetics, Inc. Inhibiteurs hétérobifonctionnels de e-sélectine et de galectine -3
CN108299525B (zh) * 2018-01-05 2021-03-26 佛山科学技术学院 路易斯寡糖-x的合成方法
JP7455064B2 (ja) 2018-03-05 2024-03-25 グリコミメティクス， インコーポレイテッド 急性骨髄性白血病および関連状態を処置する方法
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
CN109762032A (zh) * 2019-01-16 2019-05-17 天津科技大学 一种磺酸化路易斯x三糖及其合成方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023031A1 (fr) * 1992-05-08 1993-11-25 The Biomembrane Institute Substances mimetiques polyvalentes et substances mimetiques peptidiques destinees a bloquer l'interaction cellulaire dependant de l'hydrate de carbone et a provoquer la reponse anti-hydrate de carbone des lymphocytes t
US5763413A (en) * 1993-03-04 1998-06-09 Mect Corporation Lewis-associated compound, process for producing the same, and anti-inflammatory
JPH08510729A (ja) * 1993-05-14 1996-11-12 サイテル コーポレイション 細胞接着のインヒビターとしてのシアリルＬｅ▲上ｘ▼類似体
AU4316196A (en) * 1994-12-28 1996-07-19 Sumitomo Pharmaceuticals Company, Limited Lewis x derivative and process for producing the same

Also Published As

Publication number Publication date
NO990497L (no) 1999-03-24
CO4900075A1 (es) 2000-03-27
TR199900245T2 (xx) 1999-05-21
KR20000029862A (ko) 2000-05-25
BR9711117A (pt) 1999-09-08
PL331286A1 (en) 1999-07-05
NO990497D0 (no) 1999-02-03
AR008283A1 (es) 1999-12-29
CA2260854A1 (fr) 1998-02-19
CZ39099A3 (cs) 1999-05-12
AU720381B2 (en) 2000-06-01
JP2000516224A (ja) 2000-12-05
EP0920437A1 (fr) 1999-06-09
CN1227563A (zh) 1999-09-01
SK15699A3 (en) 1999-07-12
WO1998006730A1 (fr) 1998-02-19
PE99298A1 (es) 1999-01-21
AU4378897A (en) 1998-03-06
IL127908A0 (en) 1999-11-30
NZ334048A (en) 2000-05-26

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