AU4378897A - Modified oligosaccharides - Google Patents
Modified oligosaccharidesInfo
- Publication number
- AU4378897A AU4378897A AU43788/97A AU4378897A AU4378897A AU 4378897 A AU4378897 A AU 4378897A AU 43788/97 A AU43788/97 A AU 43788/97A AU 4378897 A AU4378897 A AU 4378897A AU 4378897 A AU4378897 A AU 4378897A
- Authority
- AU
- Australia
- Prior art keywords
- modified oligosaccharides
- oligosaccharides
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96810526 | 1996-08-08 | ||
EP96810526 | 1996-08-08 | ||
EP96810527 | 1996-08-08 | ||
EP96810527 | 1996-08-08 | ||
EP96810636 | 1996-09-26 | ||
EP96810636 | 1996-09-26 | ||
PCT/EP1997/004279 WO1998006730A1 (en) | 1996-08-08 | 1997-08-06 | Modified oligosaccharides |
Publications (2)
Publication Number | Publication Date |
---|---|
AU4378897A true AU4378897A (en) | 1998-03-06 |
AU720381B2 AU720381B2 (en) | 2000-06-01 |
Family
ID=27237868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU43788/97A Ceased AU720381B2 (en) | 1996-08-08 | 1997-08-06 | Modified oligosaccharides |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0920437A1 (en) |
JP (1) | JP2000516224A (en) |
KR (1) | KR20000029862A (en) |
CN (1) | CN1227563A (en) |
AR (1) | AR008283A1 (en) |
AU (1) | AU720381B2 (en) |
BR (1) | BR9711117A (en) |
CA (1) | CA2260854A1 (en) |
CO (1) | CO4900075A1 (en) |
CZ (1) | CZ39099A3 (en) |
ID (1) | ID18010A (en) |
IL (1) | IL127908A0 (en) |
NO (1) | NO990497L (en) |
NZ (1) | NZ334048A (en) |
PE (1) | PE99298A1 (en) |
PL (1) | PL331286A1 (en) |
SK (1) | SK15699A3 (en) |
TR (1) | TR199900245T2 (en) |
WO (1) | WO1998006730A1 (en) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5888984A (en) * | 1994-05-12 | 1999-03-30 | Dermal Research Laboratories, Inc. | Pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same |
WO2000044367A2 (en) | 1999-02-01 | 2000-08-03 | Dermal Research Laboratories, Inc. | A pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same |
US7879824B2 (en) | 2001-07-31 | 2011-02-01 | Dermal Research Laboratories, Inc. | Methods of preventing or treating diseases and conditions using complex carbohydrates |
WO2004004636A2 (en) * | 2002-07-03 | 2004-01-15 | Glycomimetics, Inc. | Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis |
ES2334220T3 (en) | 2002-10-11 | 2010-03-08 | Astellas Pharma Europe B.V. | GLUCOSE-BASED COMPOUNDS WITH AFFINITY FOR P-SELECTIVE. |
JP2007524658A (en) * | 2003-11-19 | 2007-08-30 | グリコミメティクス, インコーポレイテッド | Glucose mimetic antagonists for both E- and P-selectin |
US20090036386A1 (en) * | 2005-05-25 | 2009-02-05 | Glycomimetics, Inc | Heterobifunctional compounds for selectin inhibition |
PL1934236T3 (en) | 2005-09-02 | 2013-04-30 | Glycomimetics Inc | Heterobifunctional pan-selectin inhibitors |
AU2008216794A1 (en) * | 2007-02-09 | 2008-08-21 | Glycomimetics, Inc. | Methods of use of glycomimetics with replacements for hexoses and N-acetyl hexosamines |
AU2008336249B2 (en) | 2007-12-10 | 2015-01-29 | The University Of Queensland | Treatment and prophylaxis |
WO2009126556A1 (en) | 2008-04-08 | 2009-10-15 | Glycomimetics, Inc. | Pan-selectin inhibitor with enhanced pharmacokinetic activity |
US8921328B2 (en) | 2010-09-14 | 2014-12-30 | Glycomimetics, Inc. | E-selectin antagonists |
WO2013096926A1 (en) | 2011-12-22 | 2013-06-27 | Glycomimetics, Inc. | E-selectin antagonist compounds, compositions, and methods of use |
LT2928476T (en) | 2012-12-07 | 2018-05-25 | Glycomimetics, Inc. | Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells |
SI3227310T1 (en) | 2014-12-03 | 2019-11-29 | Glycomimetics Inc | Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors |
WO2017127422A1 (en) | 2016-01-22 | 2017-07-27 | Glycomimetics, Inc. | Glycomimetic inhibitors of pa-il and pa-iil lectins |
US11291678B2 (en) | 2016-03-02 | 2022-04-05 | Glycomimetics, Inc | Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin |
JP2019524791A (en) | 2016-08-08 | 2019-09-05 | グリコミメティクス, インコーポレイテッド | Combinations of T cell checkpoint inhibitors with inhibitors of E-selectin or inhibitors of CXCR4 or with heterobifunctional inhibitors of both E-selectin and CXCR4 |
KR20240046288A (en) | 2016-10-07 | 2024-04-08 | 글리코미메틱스, 인크. | Highly potent multimeric e-selectin antagonists |
CA3054605A1 (en) | 2017-03-15 | 2018-09-20 | Glycomimetics, Inc. | Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists |
WO2019108750A1 (en) | 2017-11-30 | 2019-06-06 | Glycomimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
JP7304863B2 (en) | 2017-12-29 | 2023-07-07 | グリコミメティクス, インコーポレイテッド | Heterobifunctional inhibitors of E-selectin and galectin-3 |
CN108299525B (en) * | 2018-01-05 | 2021-03-26 | 佛山科学技术学院 | Method for synthesizing Lewis oligose-X |
US11707474B2 (en) | 2018-03-05 | 2023-07-25 | Glycomimetics, Inc. | Methods for treating acute myeloid leukemia and related conditions |
US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
CN109762032A (en) * | 2019-01-16 | 2019-05-17 | 天津科技大学 | A kind of sulfonated lewis X trisaccharide and its synthetic method and application |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993023031A1 (en) * | 1992-05-08 | 1993-11-25 | The Biomembrane Institute | Multivalent mimetics and peptide mimetics for blocking carbohydrate-dependent cellular interaction and for eliciting anticarbohydrate t-cell response |
US5763413A (en) * | 1993-03-04 | 1998-06-09 | Mect Corporation | Lewis-associated compound, process for producing the same, and anti-inflammatory |
SK141695A3 (en) * | 1993-05-14 | 1996-10-02 | Cytel Corp | Analogous compound sialyl lex, pharmaceutical agent containing this compound and method of preparation of lactoseammoniacal salt |
EP0801071A4 (en) * | 1994-12-28 | 1999-01-13 | Sumitomo Pharma | Lewis x derivative and process for producing the same |
-
1997
- 1997-08-06 JP JP10509358A patent/JP2000516224A/en active Pending
- 1997-08-06 CZ CZ99390A patent/CZ39099A3/en unknown
- 1997-08-06 NZ NZ334048A patent/NZ334048A/en unknown
- 1997-08-06 IL IL12790897A patent/IL127908A0/en unknown
- 1997-08-06 PL PL97331286A patent/PL331286A1/en unknown
- 1997-08-06 CN CN97197077A patent/CN1227563A/en active Pending
- 1997-08-06 WO PCT/EP1997/004279 patent/WO1998006730A1/en not_active Application Discontinuation
- 1997-08-06 AU AU43788/97A patent/AU720381B2/en not_active Ceased
- 1997-08-06 SK SK156-99A patent/SK15699A3/en unknown
- 1997-08-06 EP EP97941916A patent/EP0920437A1/en not_active Withdrawn
- 1997-08-06 TR TR1999/00245T patent/TR199900245T2/en unknown
- 1997-08-06 KR KR1019997001025A patent/KR20000029862A/en not_active Application Discontinuation
- 1997-08-06 BR BR9711117-1A patent/BR9711117A/en not_active Application Discontinuation
- 1997-08-06 CA CA002260854A patent/CA2260854A1/en not_active Abandoned
- 1997-08-06 AR ARP970103580A patent/AR008283A1/en unknown
- 1997-08-07 PE PE1997000688A patent/PE99298A1/en not_active Application Discontinuation
- 1997-08-08 ID IDP972766A patent/ID18010A/en unknown
- 1997-08-08 CO CO97045596A patent/CO4900075A1/en unknown
-
1999
- 1999-02-03 NO NO990497A patent/NO990497L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
SK15699A3 (en) | 1999-07-12 |
ID18010A (en) | 1998-02-19 |
WO1998006730A1 (en) | 1998-02-19 |
AR008283A1 (en) | 1999-12-29 |
CA2260854A1 (en) | 1998-02-19 |
NZ334048A (en) | 2000-05-26 |
KR20000029862A (en) | 2000-05-25 |
PE99298A1 (en) | 1999-01-21 |
AU720381B2 (en) | 2000-06-01 |
CO4900075A1 (en) | 2000-03-27 |
IL127908A0 (en) | 1999-11-30 |
BR9711117A (en) | 1999-09-08 |
CN1227563A (en) | 1999-09-01 |
PL331286A1 (en) | 1999-07-05 |
NO990497D0 (en) | 1999-02-03 |
JP2000516224A (en) | 2000-12-05 |
TR199900245T2 (en) | 1999-05-21 |
CZ39099A3 (en) | 1999-05-12 |
EP0920437A1 (en) | 1999-06-09 |
NO990497L (en) | 1999-03-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FGA | Letters patent sealed or granted (standard patent) | ||
MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |