AU4378897A - Modified oligosaccharides - Google Patents
Modified oligosaccharidesInfo
- Publication number
- AU4378897A AU4378897A AU43788/97A AU4378897A AU4378897A AU 4378897 A AU4378897 A AU 4378897A AU 43788/97 A AU43788/97 A AU 43788/97A AU 4378897 A AU4378897 A AU 4378897A AU 4378897 A AU4378897 A AU 4378897A
- Authority
- AU
- Australia
- Prior art keywords
- modified oligosaccharides
- oligosaccharides
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96810527 | 1996-08-08 | ||
EP96810527 | 1996-08-08 | ||
EP96810526 | 1996-08-08 | ||
EP96810526 | 1996-08-08 | ||
EP96810636 | 1996-09-26 | ||
EP96810636 | 1996-09-26 | ||
PCT/EP1997/004279 WO1998006730A1 (en) | 1996-08-08 | 1997-08-06 | Modified oligosaccharides |
Publications (2)
Publication Number | Publication Date |
---|---|
AU4378897A true AU4378897A (en) | 1998-03-06 |
AU720381B2 AU720381B2 (en) | 2000-06-01 |
Family
ID=27237868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU43788/97A Ceased AU720381B2 (en) | 1996-08-08 | 1997-08-06 | Modified oligosaccharides |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0920437A1 (en) |
JP (1) | JP2000516224A (en) |
KR (1) | KR20000029862A (en) |
CN (1) | CN1227563A (en) |
AR (1) | AR008283A1 (en) |
AU (1) | AU720381B2 (en) |
BR (1) | BR9711117A (en) |
CA (1) | CA2260854A1 (en) |
CO (1) | CO4900075A1 (en) |
CZ (1) | CZ39099A3 (en) |
ID (1) | ID18010A (en) |
IL (1) | IL127908A0 (en) |
NO (1) | NO990497L (en) |
NZ (1) | NZ334048A (en) |
PE (1) | PE99298A1 (en) |
PL (1) | PL331286A1 (en) |
SK (1) | SK15699A3 (en) |
TR (1) | TR199900245T2 (en) |
WO (1) | WO1998006730A1 (en) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5888984A (en) * | 1994-05-12 | 1999-03-30 | Dermal Research Laboratories, Inc. | Pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same |
AU2745700A (en) | 1999-02-01 | 2000-08-18 | Dermal Research Laboratories, Inc. | A pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same |
US7879824B2 (en) | 2001-07-31 | 2011-02-01 | Dermal Research Laboratories, Inc. | Methods of preventing or treating diseases and conditions using complex carbohydrates |
US20040096396A1 (en) * | 2002-07-03 | 2004-05-20 | Glycomimetics, Inc. | Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis |
ES2334220T3 (en) | 2002-10-11 | 2010-03-08 | Astellas Pharma Europe B.V. | GLUCOSE-BASED COMPOUNDS WITH AFFINITY FOR P-SELECTIVE. |
US20050187171A1 (en) * | 2003-11-19 | 2005-08-25 | Glycomimetics, Inc. | Glycomimetic antagonists for both E-and P-selectins |
US20090036386A1 (en) * | 2005-05-25 | 2009-02-05 | Glycomimetics, Inc | Heterobifunctional compounds for selectin inhibition |
JP5209476B2 (en) | 2005-09-02 | 2013-06-12 | グリコミメティクス, インコーポレイテッド | Heterobifunctional all-selectin inhibitor |
CA2677747A1 (en) * | 2007-02-09 | 2008-08-21 | Glycomimetics, Inc. | Methods of use of glycomimetics with replacements for hexoses and n-acetyl hexosamines |
WO2009073911A1 (en) | 2007-12-10 | 2009-06-18 | Mater Medical Research Institute | Treatment and prophylaxis |
US8895510B2 (en) | 2008-04-08 | 2014-11-25 | Glycomimetics, Inc. | Pan-selectin inhibitor with enhanced pharmacokinetic activity |
WO2012037034A1 (en) | 2010-09-14 | 2012-03-22 | Glycomimetics, Inc. | E-selectin antagonists |
AU2012358150B2 (en) | 2011-12-22 | 2017-07-20 | Glycomimetics, Inc. | E-selectin antagonist compounds, compositions, and methods of use |
CA2891514C (en) | 2012-12-07 | 2020-08-25 | Glycomimetics, Inc. | Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells |
CA2968391C (en) | 2014-12-03 | 2022-04-26 | Glycomimetics, Inc. | Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors |
WO2017127422A1 (en) | 2016-01-22 | 2017-07-27 | Glycomimetics, Inc. | Glycomimetic inhibitors of pa-il and pa-iil lectins |
US11291678B2 (en) | 2016-03-02 | 2022-04-05 | Glycomimetics, Inc | Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin |
EP3497131B1 (en) | 2016-08-08 | 2022-03-09 | GlycoMimetics, Inc. | Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4. |
JP7069136B2 (en) | 2016-10-07 | 2022-05-17 | グリコミメティクス, インコーポレイテッド | Extremely potent multimeric E-selectin antagonist |
US11197877B2 (en) | 2017-03-15 | 2021-12-14 | Glycomimetics. Inc. | Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists |
US11712446B2 (en) | 2017-11-30 | 2023-08-01 | Glycomimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
EP3732186A1 (en) | 2017-12-29 | 2020-11-04 | GlycoMimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
CN108299525B (en) * | 2018-01-05 | 2021-03-26 | 佛山科学技术学院 | Method for synthesizing Lewis oligose-X |
CN111867601A (en) | 2018-03-05 | 2020-10-30 | 糖模拟物有限公司 | Methods for treating acute myeloid leukemia and related disorders |
US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
CN109762032A (en) * | 2019-01-16 | 2019-05-17 | 天津科技大学 | A kind of sulfonated lewis X trisaccharide and its synthetic method and application |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993023031A1 (en) * | 1992-05-08 | 1993-11-25 | The Biomembrane Institute | Multivalent mimetics and peptide mimetics for blocking carbohydrate-dependent cellular interaction and for eliciting anticarbohydrate t-cell response |
CA2157489A1 (en) * | 1993-03-04 | 1994-09-15 | Masaaki Numata | Lewis-associated compound, process for producing the same, and anti-inflammatory |
EP0698031A4 (en) * | 1993-05-14 | 1997-07-09 | Cytel Corp | SIALYL LE x ANALOGUES AS INHIBITORS OF CELLULAR ADHESION |
CN1176644A (en) * | 1994-12-28 | 1998-03-18 | 住友制药株式会社 | Lewis X derivative and process for producing the same |
-
1997
- 1997-08-06 WO PCT/EP1997/004279 patent/WO1998006730A1/en not_active Application Discontinuation
- 1997-08-06 EP EP97941916A patent/EP0920437A1/en not_active Withdrawn
- 1997-08-06 AU AU43788/97A patent/AU720381B2/en not_active Ceased
- 1997-08-06 BR BR9711117-1A patent/BR9711117A/en not_active Application Discontinuation
- 1997-08-06 IL IL12790897A patent/IL127908A0/en unknown
- 1997-08-06 PL PL97331286A patent/PL331286A1/en unknown
- 1997-08-06 SK SK156-99A patent/SK15699A3/en unknown
- 1997-08-06 CZ CZ99390A patent/CZ39099A3/en unknown
- 1997-08-06 AR ARP970103580A patent/AR008283A1/en unknown
- 1997-08-06 CA CA002260854A patent/CA2260854A1/en not_active Abandoned
- 1997-08-06 CN CN97197077A patent/CN1227563A/en active Pending
- 1997-08-06 NZ NZ334048A patent/NZ334048A/en unknown
- 1997-08-06 JP JP10509358A patent/JP2000516224A/en active Pending
- 1997-08-06 KR KR1019997001025A patent/KR20000029862A/en not_active Application Discontinuation
- 1997-08-06 TR TR1999/00245T patent/TR199900245T2/en unknown
- 1997-08-07 PE PE1997000688A patent/PE99298A1/en not_active Application Discontinuation
- 1997-08-08 ID IDP972766A patent/ID18010A/en unknown
- 1997-08-08 CO CO97045596A patent/CO4900075A1/en unknown
-
1999
- 1999-02-03 NO NO990497A patent/NO990497L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CO4900075A1 (en) | 2000-03-27 |
JP2000516224A (en) | 2000-12-05 |
AU720381B2 (en) | 2000-06-01 |
IL127908A0 (en) | 1999-11-30 |
SK15699A3 (en) | 1999-07-12 |
ID18010A (en) | 1998-02-19 |
NZ334048A (en) | 2000-05-26 |
TR199900245T2 (en) | 1999-05-21 |
EP0920437A1 (en) | 1999-06-09 |
PL331286A1 (en) | 1999-07-05 |
BR9711117A (en) | 1999-09-08 |
NO990497L (en) | 1999-03-24 |
NO990497D0 (en) | 1999-02-03 |
CA2260854A1 (en) | 1998-02-19 |
CZ39099A3 (en) | 1999-05-12 |
PE99298A1 (en) | 1999-01-21 |
CN1227563A (en) | 1999-09-01 |
WO1998006730A1 (en) | 1998-02-19 |
KR20000029862A (en) | 2000-05-25 |
AR008283A1 (en) | 1999-12-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FGA | Letters patent sealed or granted (standard patent) | ||
MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |