PE99298A1 - Oligosacaridos modificados - Google Patents
Oligosacaridos modificadosInfo
- Publication number
- PE99298A1 PE99298A1 PE1997000688A PE00068897A PE99298A1 PE 99298 A1 PE99298 A1 PE 99298A1 PE 1997000688 A PE1997000688 A PE 1997000688A PE 00068897 A PE00068897 A PE 00068897A PE 99298 A1 PE99298 A1 PE 99298A1
- Authority
- PE
- Peru
- Prior art keywords
- glcnac
- compounds
- formula
- preferred
- tetrahidropirano
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96810527 | 1996-08-08 | ||
EP96810526 | 1996-08-08 | ||
EP96810636 | 1996-09-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE99298A1 true PE99298A1 (es) | 1999-01-21 |
Family
ID=27237868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1997000688A PE99298A1 (es) | 1996-08-08 | 1997-08-07 | Oligosacaridos modificados |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0920437A1 (fr) |
JP (1) | JP2000516224A (fr) |
KR (1) | KR20000029862A (fr) |
CN (1) | CN1227563A (fr) |
AR (1) | AR008283A1 (fr) |
AU (1) | AU720381B2 (fr) |
BR (1) | BR9711117A (fr) |
CA (1) | CA2260854A1 (fr) |
CO (1) | CO4900075A1 (fr) |
CZ (1) | CZ39099A3 (fr) |
ID (1) | ID18010A (fr) |
IL (1) | IL127908A0 (fr) |
NO (1) | NO990497L (fr) |
NZ (1) | NZ334048A (fr) |
PE (1) | PE99298A1 (fr) |
PL (1) | PL331286A1 (fr) |
SK (1) | SK15699A3 (fr) |
TR (1) | TR199900245T2 (fr) |
WO (1) | WO1998006730A1 (fr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5888984A (en) * | 1994-05-12 | 1999-03-30 | Dermal Research Laboratories, Inc. | Pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same |
EP1165097B1 (fr) * | 1999-02-01 | 2007-05-02 | Dermal Research Laboratories, Inc. | Composition pharmaceutique d'hydrates de carbone complexes l'utilisation de celle-ci |
US7879824B2 (en) | 2001-07-31 | 2011-02-01 | Dermal Research Laboratories, Inc. | Methods of preventing or treating diseases and conditions using complex carbohydrates |
US20040096396A1 (en) * | 2002-07-03 | 2004-05-20 | Glycomimetics, Inc. | Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis |
DE60329511D1 (de) | 2002-10-11 | 2009-11-12 | Astellas Pharma Europ B V | Verbindungen auf glukosebasis mit affinitüt für p-selektin |
JP2007524658A (ja) * | 2003-11-19 | 2007-08-30 | グリコミメティクス, インコーポレイテッド | E−およびp−セレクチンの両方のための糖模倣物アンタゴニスト |
WO2006127906A1 (fr) * | 2005-05-25 | 2006-11-30 | Glycomimetics, Inc. | Composes heterobifonctionnels pour l’inhibition de la selectine |
WO2007028050A1 (fr) | 2005-09-02 | 2007-03-08 | Glycomimetics, Inc. | Inhibiteurs de pan-selectine heterobifonctionnels |
AU2008216794A1 (en) * | 2007-02-09 | 2008-08-21 | Glycomimetics, Inc. | Methods of use of glycomimetics with replacements for hexoses and N-acetyl hexosamines |
WO2009073911A1 (fr) | 2007-12-10 | 2009-06-18 | Mater Medical Research Institute | Traitement et prophylaxie |
WO2009126556A1 (fr) | 2008-04-08 | 2009-10-15 | Glycomimetics, Inc. | Inhibiteur de pan-sélectine avec activité pharmacocinétique améliorée |
WO2012037034A1 (fr) | 2010-09-14 | 2012-03-22 | Glycomimetics, Inc. | Antagonistes de l'e-sélectine |
CN104039805B (zh) | 2011-12-22 | 2016-11-16 | 糖模拟物有限公司 | E-选择蛋白拮抗剂化合物、组合物及使用方法 |
EP2928476B1 (fr) | 2012-12-07 | 2018-02-14 | GlycoMimetics, Inc. | Composés, compositions et procédés utilisant des antagonistes d'e-sélectine pour la mobilisation de cellules hématopoïétiques |
WO2016089872A1 (fr) | 2014-12-03 | 2016-06-09 | Glycomimetics, Inc. | Inhibiteurs hétérobifonctionnels des e-sélectines et des récepteurs aux chimiokines cxcr4 |
CA3009836A1 (fr) | 2016-01-22 | 2017-07-27 | Glycomimetics, Inc. | Inhibiteurs glycomimetiques des lectines pa-il et pa-iil |
WO2017151708A1 (fr) | 2016-03-02 | 2017-09-08 | Glycomimetics, Inc. | Méthodes pour le traitement et/ou à la prévention de maladies cardiovasculaires par inhibition de la sélectine e |
WO2018031445A1 (fr) | 2016-08-08 | 2018-02-15 | Glycomimetics, Inc. | Combinaison d'inhibiteurs des points de contrôle des lymphocytes t avec des inhibiteurs de e-sélectine ou de cxcr4, ou avec des inhibiteurs hétérobifonctionnels de e-sélectine et de cxcr4 |
BR112019006642A2 (pt) | 2016-10-07 | 2019-07-02 | Glycomimetics Inc | antagonistas multiméricos de e-selectina altamente potentes |
CA3054605A1 (fr) | 2017-03-15 | 2018-09-20 | Glycomimetics, Inc. | Derives de galactopyranosyle-cyclohexyle utilises en tant qu'antagonistes d'e-selectine |
US11712446B2 (en) | 2017-11-30 | 2023-08-01 | Glycomimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
EP3732186A1 (fr) | 2017-12-29 | 2020-11-04 | GlycoMimetics, Inc. | Inhibiteurs hétérobifonctionnels de e-sélectine et de galectine -3 |
CN108299525B (zh) * | 2018-01-05 | 2021-03-26 | 佛山科学技术学院 | 路易斯寡糖-x的合成方法 |
JP7455064B2 (ja) | 2018-03-05 | 2024-03-25 | グリコミメティクス, インコーポレイテッド | 急性骨髄性白血病および関連状態を処置する方法 |
US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
CN109762032A (zh) * | 2019-01-16 | 2019-05-17 | 天津科技大学 | 一种磺酸化路易斯x三糖及其合成方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993023031A1 (fr) * | 1992-05-08 | 1993-11-25 | The Biomembrane Institute | Substances mimetiques polyvalentes et substances mimetiques peptidiques destinees a bloquer l'interaction cellulaire dependant de l'hydrate de carbone et a provoquer la reponse anti-hydrate de carbone des lymphocytes t |
US5763413A (en) * | 1993-03-04 | 1998-06-09 | Mect Corporation | Lewis-associated compound, process for producing the same, and anti-inflammatory |
JPH08510729A (ja) * | 1993-05-14 | 1996-11-12 | サイテル コーポレイション | 細胞接着のインヒビターとしてのシアリルLe▲上x▼類似体 |
AU4316196A (en) * | 1994-12-28 | 1996-07-19 | Sumitomo Pharmaceuticals Company, Limited | Lewis x derivative and process for producing the same |
-
1997
- 1997-08-06 IL IL12790897A patent/IL127908A0/xx unknown
- 1997-08-06 WO PCT/EP1997/004279 patent/WO1998006730A1/fr not_active Application Discontinuation
- 1997-08-06 NZ NZ334048A patent/NZ334048A/xx unknown
- 1997-08-06 EP EP97941916A patent/EP0920437A1/fr not_active Withdrawn
- 1997-08-06 JP JP10509358A patent/JP2000516224A/ja active Pending
- 1997-08-06 PL PL97331286A patent/PL331286A1/xx unknown
- 1997-08-06 TR TR1999/00245T patent/TR199900245T2/xx unknown
- 1997-08-06 AR ARP970103580A patent/AR008283A1/es unknown
- 1997-08-06 CA CA002260854A patent/CA2260854A1/fr not_active Abandoned
- 1997-08-06 CN CN97197077A patent/CN1227563A/zh active Pending
- 1997-08-06 SK SK156-99A patent/SK15699A3/sk unknown
- 1997-08-06 KR KR1019997001025A patent/KR20000029862A/ko not_active Application Discontinuation
- 1997-08-06 BR BR9711117-1A patent/BR9711117A/pt not_active Application Discontinuation
- 1997-08-06 CZ CZ99390A patent/CZ39099A3/cs unknown
- 1997-08-06 AU AU43788/97A patent/AU720381B2/en not_active Ceased
- 1997-08-07 PE PE1997000688A patent/PE99298A1/es not_active Application Discontinuation
- 1997-08-08 ID IDP972766A patent/ID18010A/id unknown
- 1997-08-08 CO CO97045596A patent/CO4900075A1/es unknown
-
1999
- 1999-02-03 NO NO990497A patent/NO990497L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO990497L (no) | 1999-03-24 |
CO4900075A1 (es) | 2000-03-27 |
TR199900245T2 (xx) | 1999-05-21 |
KR20000029862A (ko) | 2000-05-25 |
BR9711117A (pt) | 1999-09-08 |
PL331286A1 (en) | 1999-07-05 |
NO990497D0 (no) | 1999-02-03 |
AR008283A1 (es) | 1999-12-29 |
CA2260854A1 (fr) | 1998-02-19 |
ID18010A (id) | 1998-02-19 |
CZ39099A3 (cs) | 1999-05-12 |
AU720381B2 (en) | 2000-06-01 |
JP2000516224A (ja) | 2000-12-05 |
EP0920437A1 (fr) | 1999-06-09 |
CN1227563A (zh) | 1999-09-01 |
SK15699A3 (en) | 1999-07-12 |
WO1998006730A1 (fr) | 1998-02-19 |
AU4378897A (en) | 1998-03-06 |
IL127908A0 (en) | 1999-11-30 |
NZ334048A (en) | 2000-05-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration | ||
FD | Application declared void or lapsed |