ID17753A - Gas-gas terfluorinasi yang dimikroenkapsulsikan untuk penggunaan sebagai alat penayangan - Google Patents
Gas-gas terfluorinasi yang dimikroenkapsulsikan untuk penggunaan sebagai alat penayanganInfo
- Publication number
- ID17753A ID17753A IDP970681A ID970681A ID17753A ID 17753 A ID17753 A ID 17753A ID P970681 A IDP970681 A ID P970681A ID 970681 A ID970681 A ID 970681A ID 17753 A ID17753 A ID 17753A
- Authority
- ID
- Indonesia
- Prior art keywords
- microparticle
- fluorinated gas
- incorporating
- service
- calculated
- Prior art date
Links
- 239000011859 microparticle Substances 0.000 abstract 5
- 229920000249 biocompatible polymer Polymers 0.000 abstract 2
- 238000003384 imaging method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000012285 ultrasound imaging Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/481—Diagnostic techniques involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/611,248 US5611344A (en) | 1996-03-05 | 1996-03-05 | Microencapsulated fluorinated gases for use as imaging agents |
US08/745,676 US5853698A (en) | 1996-03-05 | 1996-11-08 | Method for making porous microparticles by spray drying |
Publications (1)
Publication Number | Publication Date |
---|---|
ID17753A true ID17753A (id) | 1998-01-22 |
Family
ID=27086474
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDP970681A ID17753A (id) | 1996-03-05 | 1997-03-05 | Gas-gas terfluorinasi yang dimikroenkapsulsikan untuk penggunaan sebagai alat penayangan |
Country Status (21)
Country | Link |
---|---|
US (1) | US6132699A (id) |
EP (1) | EP0904113B1 (id) |
JP (1) | JP3178724B2 (id) |
AT (1) | ATE266426T1 (id) |
AU (1) | AU721209B2 (id) |
BR (1) | BR9707936B1 (id) |
CA (1) | CA2247151C (id) |
CZ (1) | CZ281298A3 (id) |
DE (1) | DE69729088T2 (id) |
DK (1) | DK0904113T3 (id) |
ES (1) | ES2221687T3 (id) |
HK (1) | HK1020428A1 (id) |
HU (1) | HU226714B1 (id) |
ID (1) | ID17753A (id) |
IL (1) | IL126073A (id) |
MY (1) | MY124549A (id) |
NO (1) | NO312940B1 (id) |
NZ (1) | NZ331460A (id) |
PT (1) | PT904113E (id) |
TW (1) | TWI246426B (id) |
WO (1) | WO1997032609A2 (id) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5837221A (en) * | 1996-07-29 | 1998-11-17 | Acusphere, Inc. | Polymer-lipid microencapsulated gases for use as imaging agents |
US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
ZA9811087B (en) * | 1997-12-04 | 1999-06-03 | Bracco Research Sa | Automatic liquid injection system and method |
US6223455B1 (en) † | 1999-05-03 | 2001-05-01 | Acusphere, Inc. | Spray drying apparatus and methods of use |
ATE303757T1 (de) * | 1999-12-10 | 2005-09-15 | Iscience Corp | Behandlung von augenerkrankungen |
US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
US6793626B2 (en) | 2001-01-17 | 2004-09-21 | Fuji Photo Film Co., Ltd. | Ultrasonic scatterer, ultrasonic imaging method and ultrasonic imaging apparatus |
DE10119522A1 (de) * | 2001-04-20 | 2002-12-05 | Innovacell Biotechnologie Gmbh | Herstellung und Anwendung einer Suspensionszusammensetzung mit einem Ultraschall-Kontrastmittel |
JP2005514393A (ja) | 2001-12-19 | 2005-05-19 | ネクター セラピューティクス | アミノグリコシドの肺への供給 |
US6919068B2 (en) * | 2002-05-17 | 2005-07-19 | Point Biomedical Corporation | Method of preparing gas-filled polymer matrix microparticles useful for echographic imaging |
US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
US6962006B2 (en) * | 2002-12-19 | 2005-11-08 | Acusphere, Inc. | Methods and apparatus for making particles using spray dryer and in-line jet mill |
US20050171425A1 (en) * | 2004-01-16 | 2005-08-04 | Phantoms-By-Design | Medical devices having MRI-enhancing encapsulated fluids |
AU2004320514B8 (en) * | 2004-06-04 | 2009-08-27 | Acusphere, Inc. | Ultrasound contrast agent dosage formulation |
US8012457B2 (en) | 2004-06-04 | 2011-09-06 | Acusphere, Inc. | Ultrasound contrast agent dosage formulation |
CA2631492A1 (en) * | 2005-12-15 | 2007-06-21 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for oral administration |
CA2631493A1 (en) * | 2005-12-15 | 2007-06-21 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration |
DE102008045152A1 (de) * | 2008-07-09 | 2010-01-14 | Universität Duisburg-Essen | Künstliche Sauerstoffträger und ihre Verwendung |
KR101061224B1 (ko) * | 2008-10-08 | 2011-08-31 | 포항공과대학교 산학협력단 | X 선을 이용한 유동정보 측정용 캡슐 |
NL2003660C2 (en) * | 2009-10-16 | 2011-04-19 | Giskit B V | Composition and method for medical imaging of body cavities. |
JP2011140527A (ja) * | 2011-04-20 | 2011-07-21 | Acusphere Inc | 超音波造影剤の投薬処方物 |
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US4276885A (en) * | 1979-05-04 | 1981-07-07 | Rasor Associates, Inc | Ultrasonic image enhancement |
US4265251A (en) * | 1979-06-28 | 1981-05-05 | Rasor Associates, Inc. | Method of determining pressure within liquid containing vessel |
US4442843A (en) * | 1980-11-17 | 1984-04-17 | Schering, Ag | Microbubble precursors and methods for their production and use |
US4681119A (en) * | 1980-11-17 | 1987-07-21 | Schering Aktiengesellschaft | Method of production and use of microbubble precursors |
US4657756A (en) * | 1980-11-17 | 1987-04-14 | Schering Aktiengesellschaft | Microbubble precursors and apparatus for their production and use |
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DE3141641A1 (de) * | 1981-10-16 | 1983-04-28 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Ultraschall-kontrastmittel und dessen herstellung |
US4637905A (en) * | 1982-03-04 | 1987-01-20 | Batelle Development Corporation | Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or ε-caprolactones |
US4718433A (en) * | 1983-01-27 | 1988-01-12 | Feinstein Steven B | Contrast agents for ultrasonic imaging |
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US4888176A (en) * | 1984-05-21 | 1989-12-19 | Massachusetts Institute Of Technology | Controlled drug delivery high molecular weight polyanhydrides |
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DE3688613T2 (de) * | 1985-11-18 | 1994-01-13 | Access Pharma Inc | Polychelierende stoffe für abbildung- und spektralerhöhung (und spektrale verschiebung). |
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FR2602774B1 (fr) * | 1986-07-29 | 1990-10-19 | Atta | Nouvelles molecules amphiphiles polyhydroxylees et perfluoroalkylees ayant des proprietes tensioactives |
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US4857311A (en) * | 1987-07-31 | 1989-08-15 | Massachusetts Institute Of Technology | Polyanhydrides with improved hydrolytic degradation properties |
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US5171755A (en) * | 1988-04-29 | 1992-12-15 | Hemagen/Pfc | Emulsions of highly fluorinated organic compounds |
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US5114703A (en) * | 1989-05-30 | 1992-05-19 | Alliance Pharmaceutical Corp. | Percutaneous lymphography using particulate fluorocarbon emulsions |
DE3926934A1 (de) * | 1989-08-16 | 1991-02-21 | Deutsches Krebsforsch | Hyperthermie-mikrowellenapplikator zur erwaermung einer begrenzten umgebung in einem dissipativen medium |
JPH062134B2 (ja) * | 1989-09-08 | 1994-01-12 | 株式会社東芝 | 超音波診断装置 |
US5149319A (en) * | 1990-09-11 | 1992-09-22 | Unger Evan C | Methods for providing localized therapeutic heat to biological tissues and fluids |
US5209720A (en) * | 1989-12-22 | 1993-05-11 | Unger Evan C | Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes |
US5088499A (en) * | 1989-12-22 | 1992-02-18 | Unger Evan C | Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same |
US5352435A (en) * | 1989-12-22 | 1994-10-04 | Unger Evan C | Ionophore containing liposomes for ultrasound imaging |
US5585112A (en) * | 1989-12-22 | 1996-12-17 | Imarx Pharmaceutical Corp. | Method of preparing gas and gaseous precursor-filled microspheres |
US5230882A (en) * | 1989-12-22 | 1993-07-27 | Unger Evan C | Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same |
US5123414A (en) * | 1989-12-22 | 1992-06-23 | Unger Evan C | Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same |
US5334381A (en) * | 1989-12-22 | 1994-08-02 | Unger Evan C | Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same |
US5228446A (en) * | 1989-12-22 | 1993-07-20 | Unger Evan C | Gas filled liposomes and their use as ultrasonic contrast agents |
DE4004430A1 (de) * | 1990-02-09 | 1991-08-14 | Schering Ag | Aus polyaldehyden aufgebaute kontrastmittel |
US5445813A (en) * | 1992-11-02 | 1995-08-29 | Bracco International B.V. | Stable microbubble suspensions as enhancement agents for ultrasound echography |
US5578292A (en) * | 1991-11-20 | 1996-11-26 | Bracco International B.V. | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
US5137928A (en) * | 1990-04-26 | 1992-08-11 | Hoechst Aktiengesellschaft | Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents |
AU636481B2 (en) * | 1990-05-18 | 1993-04-29 | Bracco International B.V. | Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography |
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JP3247374B2 (ja) * | 1990-10-05 | 2002-01-15 | ブラッコ インターナショナル ベスローテン フェンノートシャップ | 超音波エコグラフィーに適切な中空気体封入微小球の安定懸濁物の製造のための方法 |
US5236693A (en) * | 1990-11-14 | 1993-08-17 | Brigham And Women's Hospital | Medical ultrasound contrast agent and method of using same |
DE4100470A1 (de) * | 1991-01-09 | 1992-07-16 | Byk Gulden Lomberg Chem Fab | Echokontrastmittel |
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GB9106673D0 (en) * | 1991-03-28 | 1991-05-15 | Hafslund Nycomed As | Improvements in or relating to contrast agents |
GB9106686D0 (en) * | 1991-03-28 | 1991-05-15 | Hafslund Nycomed As | Improvements in or relating to contrast agents |
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ATE151993T1 (de) * | 1991-07-05 | 1997-05-15 | Nycomed Imaging As | Verbesserungen an kontrastmitteln |
FR2679150A1 (fr) * | 1991-07-17 | 1993-01-22 | Atta | Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations. |
NZ244147A (en) * | 1991-09-03 | 1994-09-27 | Hoechst Ag | Echogenic particles which comprise a gas and at least one shaping substance, and their use as diagnostic agents |
HU218018B (hu) * | 1991-09-17 | 2000-05-28 | Sonus Pharmaceuticals Inc. | Gázos ultrahang-kontrasztanyag és eljárás ultrahang kontrasztanyaghoz megfelelő gázok kiválasztására |
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IL104084A (en) * | 1992-01-24 | 1996-09-12 | Bracco Int Bv | Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them |
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DE4219723A1 (de) * | 1992-06-13 | 1993-12-16 | Schering Ag | Mikropartikel, Verfahren zu deren Herstellung, sowie die Verwendung dieser in der Diagnostik |
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US5565215A (en) * | 1993-07-23 | 1996-10-15 | Massachusettes Institute Of Technology | Biodegradable injectable particles for imaging |
JPH08151335A (ja) * | 1994-09-27 | 1996-06-11 | Otsuka Pharmaceut Co Ltd | 超音波造影剤およびその製造方法 |
DE19510690A1 (de) * | 1995-03-14 | 1996-09-19 | Schering Ag | Polymere Nano- und/oder Mikropartikel, Verfahren zu deren Herstellung, sowie Verwendung in medizinischen Diagnostik und Therapie |
WO1996040277A2 (en) * | 1995-06-07 | 1996-12-19 | Brown University Research Foundation | Spray dried polymeric microparticles containing imaging agents |
AU1354497A (en) * | 1995-12-21 | 1997-07-14 | Drexel University | Hollow polymer microcapsules and method of producing |
-
1997
- 1997-02-27 DK DK97906791T patent/DK0904113T3/da active
- 1997-02-27 AT AT97906791T patent/ATE266426T1/de active
- 1997-02-27 CZ CZ982812A patent/CZ281298A3/cs unknown
- 1997-02-27 JP JP53183897A patent/JP3178724B2/ja not_active Expired - Fee Related
- 1997-02-27 BR BRPI9707936-7A patent/BR9707936B1/pt active IP Right Grant
- 1997-02-27 EP EP97906791A patent/EP0904113B1/en not_active Expired - Lifetime
- 1997-02-27 NZ NZ331460A patent/NZ331460A/xx not_active IP Right Cessation
- 1997-02-27 CA CA002247151A patent/CA2247151C/en not_active Expired - Fee Related
- 1997-02-27 PT PT97906791T patent/PT904113E/pt unknown
- 1997-02-27 DE DE69729088T patent/DE69729088T2/de not_active Expired - Lifetime
- 1997-02-27 IL IL12607397A patent/IL126073A/en not_active IP Right Cessation
- 1997-02-27 HU HU9902897A patent/HU226714B1/hu not_active IP Right Cessation
- 1997-02-27 ES ES97906791T patent/ES2221687T3/es not_active Expired - Lifetime
- 1997-02-27 WO PCT/US1997/003117 patent/WO1997032609A2/en active IP Right Grant
- 1997-02-27 AU AU21392/97A patent/AU721209B2/en not_active Ceased
- 1997-03-04 MY MYPI97000858A patent/MY124549A/en unknown
- 1997-03-05 ID IDP970681A patent/ID17753A/id unknown
- 1997-03-10 TW TW086102918A patent/TWI246426B/zh not_active IP Right Cessation
-
1998
- 1998-09-04 NO NO19984089A patent/NO312940B1/no active IP Right Review Request
- 1998-09-22 US US09/158,295 patent/US6132699A/en not_active Expired - Lifetime
-
1999
- 1999-09-29 HK HK99104237A patent/HK1020428A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2247151A1 (en) | 1997-09-12 |
AU721209B2 (en) | 2000-06-29 |
BR9707936B1 (pt) | 2010-12-14 |
NO984089L (no) | 1998-09-04 |
NO312940B1 (no) | 2002-07-22 |
HU226714B1 (en) | 2009-07-28 |
US6132699A (en) | 2000-10-17 |
CZ281298A3 (cs) | 1999-01-13 |
ATE266426T1 (de) | 2004-05-15 |
PT904113E (pt) | 2004-09-30 |
NZ331460A (en) | 1998-12-23 |
TWI246426B (en) | 2006-01-01 |
BR9707936A (pt) | 2000-01-04 |
JP3178724B2 (ja) | 2001-06-25 |
HK1020428A1 (en) | 2000-04-20 |
WO1997032609A3 (en) | 1998-01-29 |
CA2247151C (en) | 2008-05-20 |
DE69729088D1 (de) | 2004-06-17 |
HUP9902897A3 (en) | 2000-03-28 |
HUP9902897A2 (hu) | 2000-01-28 |
DE69729088T2 (de) | 2005-05-12 |
DK0904113T3 (da) | 2004-08-30 |
MY124549A (en) | 2006-06-30 |
JP2000501745A (ja) | 2000-02-15 |
AU2139297A (en) | 1997-09-22 |
WO1997032609A2 (en) | 1997-09-12 |
ES2221687T3 (es) | 2005-01-01 |
IL126073A0 (en) | 1999-05-09 |
EP0904113B1 (en) | 2004-05-12 |
EP0904113A2 (en) | 1999-03-31 |
NO984089D0 (no) | 1998-09-04 |
IL126073A (en) | 2002-02-10 |
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