HUT48599A - Process for producing 2-aminoisoquinoline derivatives and pharmaceutical compositions comprising the compounds - Google Patents

Process for producing 2-aminoisoquinoline derivatives and pharmaceutical compositions comprising the compounds

Info

Publication number
HUT48599A
HUT48599A HU876132A HU613287A HUT48599A HU T48599 A HUT48599 A HU T48599A HU 876132 A HU876132 A HU 876132A HU 613287 A HU613287 A HU 613287A HU T48599 A HUT48599 A HU T48599A
Authority
HU
Hungary
Prior art keywords
compounds
pharmaceutical compositions
producing
aminoisoquinoline derivatives
derivatives
Prior art date
Application number
HU876132A
Other languages
English (en)
Other versions
HU198458B (en
Inventor
Endre Palosi
Dezsoe Korbonits
Leventene Molnar
Gyoergyne Szvoboda
Laszlo Harsing
Gyoergy Simon
Vera Gergely
Peter Koermoeczy
Sandor Virag
Tamasne Marmarosi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Priority to HU876132A priority Critical patent/HU198458B/hu
Priority to IL88639A priority patent/IL88639A/xx
Priority to ZA889285A priority patent/ZA889285B/xx
Priority to NZ227416A priority patent/NZ227416A/en
Priority to CA000586780A priority patent/CA1329209C/en
Priority to YU236088A priority patent/YU46720B/sh
Priority to PH37990A priority patent/PH25608A/en
Priority to PT89356A priority patent/PT89356B/pt
Priority to JP63335678A priority patent/JPH01213266A/ja
Priority to US07/295,920 priority patent/US4940716A/en
Priority to DD88324403A priority patent/DD283382A5/de
Priority to IE883879A priority patent/IE883879L/xx
Priority to CN88105622A priority patent/CN1022917C/zh
Priority to CS902588A priority patent/CS274495B2/cs
Priority to NO885811A priority patent/NO176177C/no
Priority to FI886046A priority patent/FI90536C/fi
Priority to DE3851697T priority patent/DE3851697D1/de
Priority to ES88121900T priority patent/ES2059485T3/es
Priority to SU884613229A priority patent/SU1676444A3/ru
Priority to AT88121900T priority patent/ATE112268T1/de
Priority to AU27628/88A priority patent/AU635463B2/en
Priority to PL1988276887A priority patent/PL155977B1/pl
Priority to EP88121900A priority patent/EP0324184B1/de
Priority to SU894613894A priority patent/SU1705287A1/ru
Publication of HUT48599A publication Critical patent/HUT48599A/hu
Publication of HU198458B publication Critical patent/HU198458B/hu
Priority to HRP920564AA priority patent/HRP920564A2/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/08Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
HU876132A 1987-12-30 1987-12-30 Process for producing 2-aminoisoquinoline derivatives and pharmaceutical compositions comprising these compounds HU198458B (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
HU876132A HU198458B (en) 1987-12-30 1987-12-30 Process for producing 2-aminoisoquinoline derivatives and pharmaceutical compositions comprising these compounds
IL88639A IL88639A (en) 1987-12-30 1988-12-09 2-amino-tetrahydro-isoquinoline derivatives and a process for the preparation thereof and pharmaceutical compositions containing same
ZA889285A ZA889285B (en) 1987-12-30 1988-12-12 2-amino-tetrahydro-isoquinoline derivatives and a process for the preparation thereof and pharmaceutical composition containing same
NZ227416A NZ227416A (en) 1987-12-30 1988-12-20 2-aminotetrahydroisoquinoline derivatives, and pharmaceutical compositions containing such
CA000586780A CA1329209C (en) 1987-12-30 1988-12-22 2-amino-tetrahydro-isoquinoline derivatives and a process for the preparation thereof and pharmaceutical compositions containing same
YU236088A YU46720B (sh) 1987-12-30 1988-12-27 Postupak za dobijanje novih 2-amino-tetrahidro-izohinolinskih derivata
PH37990A PH25608A (en) 1987-12-30 1988-12-28 3-amino-tetrahydro-isoquinoline
PT89356A PT89356B (pt) 1987-12-30 1988-12-28 Processo para a preparacao de derivados da 2-amino-tetra-hidro-isoquinolina e de composicoes farmaceuticas contendo os mesmos
JP63335678A JPH01213266A (ja) 1987-12-30 1988-12-28 2‐アミノ ‐テトラヒドロ‐イソキノリン誘導体及び該誘導体の調整方法及び該誘導体を含有する医薬組成物
CS902588A CS274495B2 (en) 1987-12-30 1988-12-29 Method of 2-aminotetrahydroisoquinoline derivatives production
DD88324403A DD283382A5 (de) 1987-12-30 1988-12-29 Verfahren zur herstellung von neuen 2-amino-1,2,3,4-tetrahydroisochinolin-derivaten
IE883879A IE883879L (en) 1987-12-30 1988-12-29 2-amino-tetrahydro-isoquinoline derivatives and a process for the preparation thereof and pharmaceutical compositions containing same
CN88105622A CN1022917C (zh) 1987-12-30 1988-12-29 2-氨基-四氢-异喹啉衍生物的制备方法
US07/295,920 US4940716A (en) 1987-12-30 1988-12-29 2-amino-tetrahydro-isoquinolene derivatives and a process for the preparation thereof and pharmaceutical compositions containing same
NO885811A NO176177C (no) 1987-12-30 1988-12-29 Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-amino-tetrahydroisokinolinderivater
SU884613229A SU1676444A3 (ru) 1987-12-30 1988-12-30 Способ получени производных 2-аминоизохинолина
DE3851697T DE3851697D1 (de) 1987-12-30 1988-12-30 2-Amino-1,2,3,4-tetrahydroisochinolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
ES88121900T ES2059485T3 (es) 1987-12-30 1988-12-30 Derivados de 2-amino-1,2,3,4-tetrahidroisoquinolina, procedimiento de su preparacion y su aplicacion como medicamento.
FI886046A FI90536C (fi) 1987-12-30 1988-12-30 Menetelmä uusien terapeuttisesti käyttökelpoisten 2-aminotetrahydroisokinoliinijohdannaisten valmistamiseksi
AT88121900T ATE112268T1 (de) 1987-12-30 1988-12-30 2-amino-1,2,3,4-tetrahydroisochinolin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
AU27628/88A AU635463B2 (en) 1987-12-30 1988-12-30 2-amino-t trahydro-isoquinoline derivatives and a process for the preparation thereof and pharmaceutical compositions containing same
PL1988276887A PL155977B1 (en) 1987-12-30 1988-12-30 Method of obtaining derivatives of 2-aminetatrahydroisoquinoline
EP88121900A EP0324184B1 (de) 1987-12-30 1988-12-30 2-Amino-1,2,3,4-tetrahydroisochinolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
SU894613894A SU1705287A1 (ru) 1987-12-30 1989-04-24 Производные 2-амино-1,2,3,4-тетрагидроизохинолина, обладающие салуретическим действием
HRP920564AA HRP920564A2 (hr) 1987-12-30 1992-09-28 2-amino-tetrahidro-izokinolinski derivati i postupak za njihovo spravljanje i farmaceutski preparati koji ih sadrže

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU876132A HU198458B (en) 1987-12-30 1987-12-30 Process for producing 2-aminoisoquinoline derivatives and pharmaceutical compositions comprising these compounds

Publications (2)

Publication Number Publication Date
HUT48599A true HUT48599A (en) 1989-06-28
HU198458B HU198458B (en) 1989-10-30

Family

ID=10971251

Family Applications (1)

Application Number Title Priority Date Filing Date
HU876132A HU198458B (en) 1987-12-30 1987-12-30 Process for producing 2-aminoisoquinoline derivatives and pharmaceutical compositions comprising these compounds

Country Status (24)

Country Link
US (1) US4940716A (hu)
EP (1) EP0324184B1 (hu)
JP (1) JPH01213266A (hu)
CN (1) CN1022917C (hu)
AT (1) ATE112268T1 (hu)
AU (1) AU635463B2 (hu)
CA (1) CA1329209C (hu)
CS (1) CS274495B2 (hu)
DD (1) DD283382A5 (hu)
DE (1) DE3851697D1 (hu)
ES (1) ES2059485T3 (hu)
FI (1) FI90536C (hu)
HR (1) HRP920564A2 (hu)
HU (1) HU198458B (hu)
IE (1) IE883879L (hu)
IL (1) IL88639A (hu)
NO (1) NO176177C (hu)
NZ (1) NZ227416A (hu)
PH (1) PH25608A (hu)
PL (1) PL155977B1 (hu)
PT (1) PT89356B (hu)
SU (2) SU1676444A3 (hu)
YU (1) YU46720B (hu)
ZA (1) ZA889285B (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005002130A1 (de) 2005-01-17 2006-07-27 Sanofi-Aventis Deutschland Gmbh Substituierte N-Aminomethylensulfonamide, ihre Herstellung und Verwendung als Arzneimittel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3037984A (en) * 1960-01-27 1962-06-05 Lakeside Lab Inc Derivatives of n-amino-1, 2, 3, 4-tetrahydroisoquinoline
EP0266949B1 (en) * 1986-10-28 1990-11-28 Smith Kline & French Laboratories Limited Tetrahydroisoquinolin-2-yl derivatives of carboxylic acids as thromboxane a2 antagonists

Also Published As

Publication number Publication date
CS274495B2 (en) 1991-04-11
HRP920564A2 (hr) 1994-04-30
NO176177B (no) 1994-11-07
AU635463B2 (en) 1993-03-18
ATE112268T1 (de) 1994-10-15
CA1329209C (en) 1994-05-03
EP0324184B1 (de) 1994-09-28
IE883879L (en) 1989-06-30
ES2059485T3 (es) 1994-11-16
YU236088A (en) 1990-02-28
NO176177C (no) 1995-02-15
HU198458B (en) 1989-10-30
US4940716A (en) 1990-07-10
AU2762888A (en) 1989-07-06
PT89356A (pt) 1989-12-29
FI90536B (fi) 1993-11-15
NO885811D0 (no) 1988-12-29
EP0324184A3 (en) 1990-05-02
ZA889285B (en) 1989-09-27
DD283382A5 (de) 1990-10-10
SU1676444A3 (ru) 1991-09-07
PL155977B1 (en) 1992-01-31
CS902588A2 (en) 1990-09-12
CN1035502A (zh) 1989-09-13
EP0324184A2 (de) 1989-07-19
PL276887A1 (en) 1989-09-04
FI90536C (fi) 1994-02-25
JPH01213266A (ja) 1989-08-28
NO885811L (no) 1989-07-03
PH25608A (en) 1991-08-08
IL88639A (en) 1992-11-15
CN1022917C (zh) 1993-12-01
DE3851697D1 (de) 1994-11-03
NZ227416A (en) 1990-11-27
IL88639A0 (en) 1989-07-31
SU1705287A1 (ru) 1992-01-15
PT89356B (pt) 1993-09-30
YU46720B (sh) 1994-04-05
FI886046A (fi) 1989-07-01

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee