HUT47940A - Process for producing substituted vinyl cefalosporins and pharmaceuticals comprising these compounds - Google Patents

Process for producing substituted vinyl cefalosporins and pharmaceuticals comprising these compounds

Info

Publication number
HUT47940A
HUT47940A HU882646A HU264688A HUT47940A HU T47940 A HUT47940 A HU T47940A HU 882646 A HU882646 A HU 882646A HU 264688 A HU264688 A HU 264688A HU T47940 A HUT47940 A HU T47940A
Authority
HU
Hungary
Prior art keywords
cefalosporins
pharmaceuticals
compounds
substituted vinyl
producing substituted
Prior art date
Application number
HU882646A
Other languages
English (en)
Other versions
HU205937B (en
Inventor
Gunter Schmidt
Karl G Metzger
Hans-Joachim Zeiler
Rainer Endermann
Ingo Haller
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of HUT47940A publication Critical patent/HUT47940A/hu
Publication of HU205937B publication Critical patent/HU205937B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU882646A 1987-05-26 1988-05-24 Process for producing substituted vinyl-cephalosporines and pharmaceutical compositions containing them HU205937B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3717664 1987-05-26
DE19873734004 DE3734004A1 (de) 1987-05-26 1987-10-08 Substituierte vinylcephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
HUT47940A true HUT47940A (en) 1989-04-28
HU205937B HU205937B (en) 1992-07-28

Family

ID=25856024

Family Applications (1)

Application Number Title Priority Date Filing Date
HU882646A HU205937B (en) 1987-05-26 1988-05-24 Process for producing substituted vinyl-cephalosporines and pharmaceutical compositions containing them

Country Status (14)

Country Link
EP (1) EP0292808B1 (hu)
JP (1) JPH0645627B2 (hu)
KR (1) KR880013950A (hu)
CN (1) CN88103202A (hu)
AU (1) AU1630188A (hu)
CA (1) CA1340154C (hu)
DE (2) DE3734004A1 (hu)
DK (1) DK284688A (hu)
ES (1) ES2062997T3 (hu)
FI (1) FI882443A (hu)
HU (1) HU205937B (hu)
IL (1) IL86478A (hu)
NO (1) NO170020C (hu)
PT (1) PT87564B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3734005A1 (de) * 1987-05-26 1988-12-15 Bayer Ag Substituierte vinylcephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3933934A1 (de) * 1989-10-03 1991-04-11 Bayer Ag Verfahren zur herstellung von 7-amino-3-((z)-1-propen-1-yl)-3-cephem-4-carbonsaeure
ATE201025T1 (de) 1991-03-08 2001-05-15 Biochemie Gmbh Verfahren zur herstellung von cephalosporinen und zwischenprodukte in diesem verfahren
US6248881B1 (en) 1991-03-08 2001-06-19 Biochemie Gmbh Intermediates and process for the production of 3-vinyl cephalosporins
KR930007261B1 (ko) * 1991-04-19 1993-08-04 한국과학기술연구원 7β-아미노-3-[3-(4-치환된 테트라졸린-5-티온-1-일)프로펜-1-일]-3-세펨-4-카르복실산 유도체 및 그 제조방법
JP3224279B2 (ja) * 1992-07-27 2001-10-29 大塚化学株式会社 セフエム化合物の製造法
KR20000002217A (ko) * 1998-06-18 2000-01-15 김종인 신규 세팔로스포린계 항생제 및 이의 제조 방법
CA2935651A1 (en) 2007-10-09 2009-04-16 Gladius Pharmaceuticals Corporation Broad spectrum beta-lactamase inhibitors
EP2968352B1 (en) 2013-03-12 2018-09-26 Gladius Pharmaceuticals Corporation Derivatized 3-styryl-cephalosporins

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769277A (en) * 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
US4255423A (en) * 1977-07-27 1981-03-10 Merck & Co., Inc. Cephalosporin compounds
US4390693A (en) 1977-07-27 1983-06-28 Merck & Co., Inc. Cephalosporin compounds
US4520022A (en) * 1983-01-28 1985-05-28 Bristol-Myers Company Substituted vinyl cephalosporins
GB8406231D0 (en) * 1984-03-09 1984-04-11 Fujisawa Pharmaceutical Co Cephem compounds
DE3508258A1 (de) * 1985-03-08 1986-09-18 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zur herstellung und ihre verwendung als und in arzneimitteln
JPS63126023A (ja) * 1986-11-14 1988-05-30 Fujitsu Ltd 表示装置
DE3734005A1 (de) * 1987-05-26 1988-12-15 Bayer Ag Substituierte vinylcephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
DE3888018D1 (de) 1994-04-07
NO170020C (no) 1992-09-02
FI882443A0 (fi) 1988-05-24
JPH0645627B2 (ja) 1994-06-15
NO882112D0 (no) 1988-05-13
DK284688A (da) 1988-11-27
DE3734004A1 (de) 1988-12-15
PT87564B (pt) 1992-09-30
AU1630188A (en) 1988-12-01
ES2062997T3 (es) 1995-01-01
NO882112L (no) 1988-11-28
CA1340154C (en) 1998-12-01
CN88103202A (zh) 1988-12-21
JPS63307885A (ja) 1988-12-15
PT87564A (pt) 1989-05-31
EP0292808B1 (de) 1994-03-02
HU205937B (en) 1992-07-28
NO170020B (no) 1992-05-25
IL86478A0 (en) 1988-11-15
KR880013950A (ko) 1988-12-22
DK284688D0 (da) 1988-05-25
IL86478A (en) 1993-02-21
EP0292808A3 (en) 1990-09-19
EP0292808A2 (de) 1988-11-30
FI882443A (fi) 1988-11-27

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee