HUT47289A - Process for producing new thienopyridinones - Google Patents

Process for producing new thienopyridinones

Info

Publication number
HUT47289A
HUT47289A HU875137A HU513787A HUT47289A HU T47289 A HUT47289 A HU T47289A HU 875137 A HU875137 A HU 875137A HU 513787 A HU513787 A HU 513787A HU T47289 A HUT47289 A HU T47289A
Authority
HU
Hungary
Prior art keywords
thienopyridinones
lower alkyl
producing new
halo
trifluoromethyl
Prior art date
Application number
HU875137A
Other languages
English (en)
Other versions
HU198060B (en
Inventor
Roy V Davies
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of HUT47289A publication Critical patent/HUT47289A/hu
Publication of HU198060B publication Critical patent/HU198060B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Liquid Crystal Substances (AREA)
HU875137A 1986-11-20 1987-11-19 Process for producing new thienopyridinones and pharmaceutical compositions comprising same HU198060B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868627698A GB8627698D0 (en) 1986-11-20 1986-11-20 Therapeutic agents

Publications (2)

Publication Number Publication Date
HUT47289A true HUT47289A (en) 1989-02-28
HU198060B HU198060B (en) 1989-07-28

Family

ID=10607612

Family Applications (1)

Application Number Title Priority Date Filing Date
HU875137A HU198060B (en) 1986-11-20 1987-11-19 Process for producing new thienopyridinones and pharmaceutical compositions comprising same

Country Status (24)

Country Link
US (1) US4877793A (hu)
EP (1) EP0269295B1 (hu)
JP (1) JPS63141984A (hu)
KR (1) KR880006247A (hu)
CN (1) CN1019491B (hu)
AT (1) ATE64736T1 (hu)
AU (1) AU599721B2 (hu)
DD (1) DD282690A5 (hu)
DE (1) DE3771039D1 (hu)
DK (1) DK599887A (hu)
ES (1) ES2038188T3 (hu)
FI (1) FI875020A (hu)
GB (1) GB8627698D0 (hu)
GR (1) GR3002500T3 (hu)
HU (1) HU198060B (hu)
IL (1) IL84505A (hu)
JO (1) JO1520B1 (hu)
MX (1) MX9428A (hu)
NO (1) NO874834L (hu)
NZ (1) NZ222554A (hu)
PH (1) PH23293A (hu)
PL (1) PL149617B1 (hu)
PT (1) PT86115B (hu)
ZA (1) ZA878306B (hu)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8726950D0 (en) * 1987-11-18 1987-12-23 Boots Co Plc Chemical process
NZ230711A (en) * 1988-09-23 1990-10-26 Ortho Pharma Corp Substituted thienopyrans as antihypertensive agents
ZA903588B (en) * 1989-05-16 1991-02-27 Merrell Dow Pharma Excitatory amino acid antagonists
US5026700A (en) * 1989-05-16 1991-06-25 Merrell Dow Pharmaceuticals Certain quinolines and thienopyridines as excitatory amino acid antagonists
US5219864A (en) * 1991-03-12 1993-06-15 Kyowa Hakko Kogyo Co., Ltd. Thienopyridine derivatives
JP2699794B2 (ja) * 1992-03-12 1998-01-19 三菱化学株式会社 チエノ〔３，２−ｂ〕ピリジン誘導体
DE4227747A1 (de) * 1992-08-21 1994-02-24 Basf Ag Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung
CA2339484A1 (en) * 1998-08-03 2000-02-17 Robert A. O'brien Pyridinones for the treatment of sexual dysfunction
US6562838B2 (en) * 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US6458804B1 (en) 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US8329924B2 (en) 2001-06-11 2012-12-11 Vertex Pharmaceuticals (Canada) Incorporated Compounds and methods for the treatment or prevention of Flavivirus infections
JP4544857B2 (ja) * 2001-06-11 2010-09-15 ヴァイロケム ファーマ インコーポレイテッド Ｆｌａｖｉｖｉｒｕｓ感染の治療または予防のための化合物および方法
WO2003020728A1 (en) 2001-08-30 2003-03-13 Pharmacia & Upjohn Company 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS
AR038117A1 (es) 2002-01-14 2004-12-29 Upjohn Co Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida
AR038294A1 (es) 2002-01-14 2005-01-12 Upjohn Co Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales
AR038118A1 (es) 2002-01-14 2004-12-29 Upjohn Co Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales
US7402608B2 (en) 2002-12-10 2008-07-22 Virochem Pharma Inc. Compounds and methods for the treatment or prevention of Flavivirus infections
KR20080016597A (ko) 2005-05-13 2008-02-21 바이로켐 파마 인코포레이티드 플라비바이러스 감염의 예방 또는 치료용 화합물 및 그의예방 또는 치료 방법
JP2008093872A (ja) * 2006-10-09 2008-04-24 Kouritsu Kogyo:Kk 表示装置
SI2104674T1 (sl) 2006-11-15 2013-09-30 Vertex Pharmaceuticals (Canada) Incorporated Tiofenski analogi za zdravljenje ali preprečevanje flavivirusnih infekcij
PL2280952T3 (pl) * 2008-05-05 2012-10-31 Merck Patent Gmbh Pochodne tienopirydonowe jako aktywatory kinazy białkowej aktywowanej przez amp
CN103517936A (zh) * 2011-04-27 2014-01-15 巴斯夫欧洲公司 基于二噻吩并吡啶酮共聚物的半导体材料
HRP20211583T1 (hr) * 2017-05-11 2022-01-07 Bristol-Myers Squibb Company Tienopiridini i benzotiofeni korisni kao irak4 inhibitori

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903095A (en) * 1972-02-18 1975-09-02 Merck & Co Inc Certain substituted-thieno{8 3,2-c{9 -pyridines
US3997545A (en) * 1973-07-23 1976-12-14 Takeda Chemical Industries, Ltd. Thienopyridine-carboxylic acid derivatives
NZ193167A (en) * 1979-03-27 1984-08-24 Boots Co Plc Quinoline derivatives and pharmaceutical compositions
JPS5742690A (en) * 1980-08-28 1982-03-10 Kanebo Ltd Thieno 3,2-b pyridinecarboxylic acid derivative
IE51542B1 (en) * 1980-09-26 1987-01-07 Boots Co Ltd Therapeutic agents
EP0126970A3 (en) * 1983-04-27 1985-11-06 Beecham Group Plc Anxiolytic and anti-depressant thienopyridine derivatives
PT79031B (en) * 1983-08-20 1986-08-22 Boots Co Plc Therapeutic agents
EP0149519B1 (en) * 1984-01-13 1990-06-27 The Boots Company PLC Use of quinolones for the manufacture of a composition for the treatment of heart failure.
AU578712B2 (en) * 1984-07-13 1988-11-03 Pandrol Limited Improvements in or relating to rail pads and rail assemblies including such pads
EP0172004B1 (en) * 1984-08-15 1990-03-21 The Boots Company PLC Quinolinones, process for their preparation and pharmaceutical compositions containing them
GB8515209D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents
GB8515207D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents

Also Published As

Publication number Publication date
US4877793A (en) 1989-10-31
DK599887D0 (da) 1987-11-16
PT86115A (en) 1987-12-01
PL149617B1 (en) 1990-03-31
PH23293A (en) 1989-06-30
FI875020A0 (fi) 1987-11-13
AU599721B2 (en) 1990-07-26
JO1520B1 (en) 1989-01-25
NO874834L (no) 1988-05-24
PT86115B (pt) 1990-08-31
DE3771039D1 (de) 1991-08-01
EP0269295A1 (en) 1988-06-01
NO874834D0 (no) 1987-11-19
JPS63141984A (ja) 1988-06-14
EP0269295B1 (en) 1991-06-26
IL84505A (en) 1990-12-23
MX9428A (es) 1993-10-01
GB8627698D0 (en) 1986-12-17
GR3002500T3 (en) 1992-12-30
ATE64736T1 (de) 1991-07-15
ZA878306B (en) 1988-05-02
KR880006247A (ko) 1988-07-22
CN87107975A (zh) 1988-06-01
DD282690A5 (de) 1990-09-19
AU8144087A (en) 1988-05-26
DK599887A (da) 1988-05-21
FI875020A (fi) 1988-05-21
ES2038188T3 (es) 1993-07-16
HU198060B (en) 1989-07-28
PL268925A1 (en) 1988-09-01
NZ222554A (en) 1989-08-29
CN1019491B (zh) 1992-12-16

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee