HUS2200050I1 - Dóziseszkalációs enzim helyettesítõ terápia savas szfingomielináz elégtelenség kezelésére - Google Patents
Dóziseszkalációs enzim helyettesítõ terápia savas szfingomielináz elégtelenség kezeléséreInfo
- Publication number
- HUS2200050I1 HUS2200050I1 HUS2200050C HUS2200050C HUS2200050I1 HU S2200050 I1 HUS2200050 I1 HU S2200050I1 HU S2200050 C HUS2200050 C HU S2200050C HU S2200050 C HUS2200050 C HU S2200050C HU S2200050 I1 HUS2200050 I1 HU S2200050I1
- Authority
- HU
- Hungary
- Prior art keywords
- replacement therapy
- dose escalation
- enzyme replacement
- acid sphingomyelinase
- treating acid
- Prior art date
Links
- 208000034012 Acid sphingomyelinase deficiency Diseases 0.000 title 1
- 238000002641 enzyme replacement therapy Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/04—Phosphoric diester hydrolases (3.1.4)
- C12Y301/04012—Sphingomyelin phosphodiesterase (3.1.4.12)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Dermatology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23811309P | 2009-08-28 | 2009-08-28 | |
EP18199358.5A EP3482767B1 (en) | 2009-08-28 | 2010-08-28 | Dose escalation enzyme replacement therapy for treating acid sphingomyelinase deficiency |
Publications (1)
Publication Number | Publication Date |
---|---|
HUS2200050I1 true HUS2200050I1 (hu) | 2022-12-28 |
Family
ID=43625265
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE10812683A HUE046598T2 (hu) | 2009-08-28 | 2010-08-28 | Dóziseszkalációs enzim helyettesítõ terápia savas szfingomielináz elégtelenség kezelésére |
HUE18199358A HUE057440T2 (hu) | 2009-08-28 | 2010-08-28 | Dóziseszkalációs enzim helyettesítõ terápia savas szfingomielináz elégtelenség kezelésére |
HUS2200050C HUS2200050I1 (hu) | 2009-08-28 | 2022-12-08 | Dóziseszkalációs enzim helyettesítõ terápia savas szfingomielináz elégtelenség kezelésére |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE10812683A HUE046598T2 (hu) | 2009-08-28 | 2010-08-28 | Dóziseszkalációs enzim helyettesítõ terápia savas szfingomielináz elégtelenség kezelésére |
HUE18199358A HUE057440T2 (hu) | 2009-08-28 | 2010-08-28 | Dóziseszkalációs enzim helyettesítõ terápia savas szfingomielináz elégtelenség kezelésére |
Country Status (26)
Country | Link |
---|---|
US (9) | US8349319B2 (hu) |
EP (3) | EP3482767B1 (hu) |
JP (7) | JP5955219B2 (hu) |
KR (5) | KR20200034828A (hu) |
CN (3) | CN106047835A (hu) |
AU (5) | AU2010286550B2 (hu) |
BR (1) | BR112012004377A2 (hu) |
CA (1) | CA2773133A1 (hu) |
CL (1) | CL2012000495A1 (hu) |
CY (1) | CY1122128T1 (hu) |
DK (2) | DK3482767T3 (hu) |
ES (2) | ES2738859T3 (hu) |
FR (1) | FR22C1062I2 (hu) |
HR (2) | HRP20211992T1 (hu) |
HU (3) | HUE046598T2 (hu) |
IL (3) | IL300625A (hu) |
LT (2) | LT3482767T (hu) |
MX (1) | MX356873B (hu) |
NL (1) | NL301211I2 (hu) |
PL (2) | PL3482767T3 (hu) |
PT (2) | PT2470199T (hu) |
RU (3) | RU2731616C2 (hu) |
SI (2) | SI3482767T1 (hu) |
TR (1) | TR201911293T4 (hu) |
WO (1) | WO2011025996A2 (hu) |
ZA (2) | ZA201201435B (hu) |
Families Citing this family (23)
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WO2006007560A2 (en) | 2004-07-01 | 2006-01-19 | University Of Pennsylvania | Targeted protein replacement for the treatment of lysosomal storage disorders |
US20080228056A1 (en) | 2007-03-13 | 2008-09-18 | Michael Blomquist | Basal rate testing using frequent blood glucose input |
US7751907B2 (en) | 2007-05-24 | 2010-07-06 | Smiths Medical Asd, Inc. | Expert system for insulin pump therapy |
US8221345B2 (en) | 2007-05-30 | 2012-07-17 | Smiths Medical Asd, Inc. | Insulin pump based expert system |
PL3252161T3 (pl) | 2007-06-06 | 2022-03-07 | Genzyme Corporation | Terapia genowa dla lizosomalnych chorób spichrzeniowych |
KR20200034828A (ko) * | 2009-08-28 | 2020-03-31 | 이칸 스쿨 오브 메디슨 엣 마운트 시나이 | 산성 스핑고미엘리나제 결핍을 치료하기 위한 투여량 단계적 증가 효소 대체 요법 |
US8882701B2 (en) | 2009-12-04 | 2014-11-11 | Smiths Medical Asd, Inc. | Advanced step therapy delivery for an ambulatory infusion pump and system |
WO2011146143A2 (en) | 2010-05-21 | 2011-11-24 | Ohmx Corporation | Detection of cancer by assaying psa enzymatic activity |
RU2018104472A (ru) | 2011-03-18 | 2019-02-22 | Джензим Корпорейшн | Ингибиторы глюкозилцерамид-синтазы |
ES2791760T3 (es) | 2011-09-07 | 2020-11-05 | Sinai School Medicine | Ceramidasa y diferenciación celular |
EP2780716B1 (en) | 2011-11-15 | 2019-07-31 | Centogene AG | Method for the diagnosis of niemann-pick disease |
LT2854910T (lt) | 2012-06-01 | 2020-05-25 | Icahn School Of Medicine At Mount Sinai | Ceramido lygiai infekcijos gydymo ir prevencijos metu |
MA37975B2 (fr) | 2012-09-11 | 2021-03-31 | Genzyme Corp | Inhibiteurs de synthase de glucosylcéramide |
PT2968479T (pt) * | 2013-03-14 | 2019-08-07 | Icahn School Med Mount Sinai | Composições terapêuticas de ceramidase ácida e métodos de fabrico e utilização |
JO3713B1 (ar) | 2013-03-15 | 2021-01-31 | Genzyme Corp | أشكال ملح (s)-كوينوكليدين-3-يل(2-(2-(4-فلوروفينيل)ثيازول-4-يل)بروبان-2-يل)كارباميت |
US10302664B2 (en) * | 2013-05-14 | 2019-05-28 | Centogene Ag | Method for the diagnosis of Niemann-Pick disease |
CA2914751C (en) * | 2013-06-07 | 2023-10-03 | Genzyme Corporation | Marker for acid sphingomyelinase disorders and uses thereof |
JP6984854B2 (ja) * | 2015-10-08 | 2021-12-22 | 国立大学法人千葉大学 | ニーマン・ピック病c型を予防または治療するための医薬組成物 |
US10569016B2 (en) | 2015-12-29 | 2020-02-25 | Tandem Diabetes Care, Inc. | System and method for switching between closed loop and open loop control of an ambulatory infusion pump |
CN111344003B (zh) * | 2017-08-24 | 2024-05-07 | 建新公司 | 酸性鞘磷脂酶缺乏症患者中异常骨病症的治疗 |
KR20200058510A (ko) | 2017-10-02 | 2020-05-27 | 데날리 테라퓨틱스 인크. | 효소 대체 요법 효소를 포함하는 융합 단백질 |
UY38238A (es) | 2018-05-25 | 2019-12-31 | Genzyme Corp | Composiciones farmacéuticas para el tratamiento de la deficiencia de esfingomielinasa ácida |
KR20230043024A (ko) | 2020-07-24 | 2023-03-30 | 젠자임 코포레이션 | 벤글루스타트를 포함하는 제약 조성물 |
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KR20200034828A (ko) * | 2009-08-28 | 2020-03-31 | 이칸 스쿨 오브 메디슨 엣 마운트 시나이 | 산성 스핑고미엘리나제 결핍을 치료하기 위한 투여량 단계적 증가 효소 대체 요법 |
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2010
- 2010-08-28 KR KR1020207008342A patent/KR20200034828A/ko not_active IP Right Cessation
- 2010-08-28 PT PT10812683T patent/PT2470199T/pt unknown
- 2010-08-28 EP EP18199358.5A patent/EP3482767B1/en active Active
- 2010-08-28 AU AU2010286550A patent/AU2010286550B2/en active Active
- 2010-08-28 KR KR1020227023712A patent/KR102608551B1/ko active IP Right Grant
- 2010-08-28 CN CN201610403228.4A patent/CN106047835A/zh active Pending
- 2010-08-28 ES ES10812683T patent/ES2738859T3/es active Active
- 2010-08-28 MX MX2012002449A patent/MX356873B/es active IP Right Grant
- 2010-08-28 PT PT181993585T patent/PT3482767T/pt unknown
- 2010-08-28 KR KR1020237040891A patent/KR20230164773A/ko active Application Filing
- 2010-08-28 KR KR1020127005293A patent/KR102094253B1/ko active IP Right Grant
- 2010-08-28 DK DK18199358.5T patent/DK3482767T3/da active
- 2010-08-28 TR TR2019/11293T patent/TR201911293T4/tr unknown
- 2010-08-28 EP EP10812683.0A patent/EP2470199B1/en active Active
- 2010-08-28 JP JP2012527054A patent/JP5955219B2/ja active Active
- 2010-08-28 CN CN2010800439108A patent/CN102596232A/zh active Pending
- 2010-08-28 SI SI201032100T patent/SI3482767T1/sl unknown
- 2010-08-28 US US12/870,790 patent/US8349319B2/en active Active
- 2010-08-28 LT LTEP18199358.5T patent/LT3482767T/lt unknown
- 2010-08-28 CA CA2773133A patent/CA2773133A1/en active Pending
- 2010-08-28 IL IL300625A patent/IL300625A/en unknown
- 2010-08-28 PL PL18199358T patent/PL3482767T3/pl unknown
- 2010-08-28 HR HRP20211992TT patent/HRP20211992T1/hr unknown
- 2010-08-28 EP EP21200695.1A patent/EP3998078A1/en active Pending
- 2010-08-28 ES ES18199358T patent/ES2902229T3/es active Active
- 2010-08-28 PL PL10812683T patent/PL2470199T3/pl unknown
- 2010-08-28 SI SI201031915T patent/SI2470199T1/sl unknown
- 2010-08-28 DK DK10812683.0T patent/DK2470199T3/da active
- 2010-08-28 RU RU2015145255A patent/RU2731616C2/ru active
- 2010-08-28 RU RU2012111823/15A patent/RU2569744C2/ru active
- 2010-08-28 WO PCT/US2010/047057 patent/WO2011025996A2/en active Application Filing
- 2010-08-28 HU HUE10812683A patent/HUE046598T2/hu unknown
- 2010-08-28 LT LTEP10812683.0T patent/LT2470199T/lt unknown
- 2010-08-28 HU HUE18199358A patent/HUE057440T2/hu unknown
- 2010-08-28 BR BR112012004377A patent/BR112012004377A2/pt not_active Application Discontinuation
- 2010-08-28 CN CN201610404696.3A patent/CN105999238A/zh active Pending
- 2010-08-28 KR KR1020217026374A patent/KR102608546B1/ko active IP Right Grant
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2012
- 2012-02-26 IL IL218324A patent/IL218324B/en active IP Right Grant
- 2012-02-27 ZA ZA2012/01435A patent/ZA201201435B/en unknown
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