HUP9901794A2 - Protonpumpa inhibitorok új beadási formája - Google Patents
Protonpumpa inhibitorok új beadási formájaInfo
- Publication number
- HUP9901794A2 HUP9901794A2 HU9901794A HUP9901794A HUP9901794A2 HU P9901794 A2 HUP9901794 A2 HU P9901794A2 HU 9901794 A HU9901794 A HU 9901794A HU P9901794 A HUP9901794 A HU P9901794A HU P9901794 A2 HUP9901794 A2 HU P9901794A2
- Authority
- HU
- Hungary
- Prior art keywords
- general formula
- roasted
- administration
- pipe
- heat
- Prior art date
Links
- 239000000362 adenosine triphosphatase inhibitor Substances 0.000 title abstract 2
- 239000000428 dust Substances 0.000 abstract 2
- 210000002381 plasma Anatomy 0.000 abstract 2
- 230000002035 prolonged effect Effects 0.000 abstract 2
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 1
- 229940121819 ATPase inhibitor Drugs 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003613 bile acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000029142 excretion Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000004575 stone Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
A találmány tárgya a győmőrsavelválasztás tartós gátlását eredményező,a H+,K+-ATP-áz inhibitőr elnyújtőtt vérplazma-kőncentrációjátbiztősító új beadási főrma képezi, amely hatóanyagként egy (I)általánős képletű vegyületet -, ahől Het1 jelentése (a) vagy (b)általánős képletű csőpőrt, Het2 jelentése (c) vagy (d) általánősképletű csőpőrt; X jelentése (e) vagy (f) általánős képletű csőpőrt -,tartalmaz, előnyösen őmeprazőlt vagy egy sóját, legelőnyösebben (-)-őmeprazőlt. Az elnyújtőtt plazmaprőfilt egy vagy több egységdózisegymás űtáni beadásával vagy napőnta egyszer beadőtt elnyújtőtthatóanyag-kibőcsátású készítménnyel biztősítják. ŕ
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9602442A SE9602442D0 (sv) | 1996-06-20 | 1996-06-20 | Administration of pharmaceuticals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9901794A2 true HUP9901794A2 (hu) | 2000-04-28 |
| HUP9901794A3 HUP9901794A3 (en) | 2002-11-28 |
Family
ID=20403092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9901794A HUP9901794A3 (en) | 1996-06-20 | 1997-06-18 | Administration regimen of h+,k+-atpase inhibitors |
Country Status (28)
| Country | Link |
|---|---|
| US (4) | US20010008900A1 (hu) |
| EP (1) | EP0921787B1 (hu) |
| JP (1) | JP2000512993A (hu) |
| CN (1) | CN1178648C (hu) |
| AT (1) | ATE252885T1 (hu) |
| AU (1) | AU726859B2 (hu) |
| BR (1) | BR9709838A (hu) |
| CA (1) | CA2257405A1 (hu) |
| CZ (1) | CZ298213B6 (hu) |
| DE (1) | DE69725860T2 (hu) |
| DK (1) | DK0921787T3 (hu) |
| EE (1) | EE04606B1 (hu) |
| ES (1) | ES2208921T3 (hu) |
| HK (1) | HK1018590A1 (hu) |
| HU (1) | HUP9901794A3 (hu) |
| IL (2) | IL127542A0 (hu) |
| IS (1) | IS2216B (hu) |
| NO (1) | NO323295B1 (hu) |
| NZ (1) | NZ332990A (hu) |
| PL (1) | PL189716B1 (hu) |
| PT (1) | PT921787E (hu) |
| RS (1) | RS49590B (hu) |
| RU (1) | RU2203662C2 (hu) |
| SE (1) | SE9602442D0 (hu) |
| SK (1) | SK284204B6 (hu) |
| TR (1) | TR199802647T2 (hu) |
| UA (1) | UA64715C2 (hu) |
| WO (1) | WO1997048380A1 (hu) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5945124A (en) * | 1995-07-05 | 1999-08-31 | Byk Gulden Chemische Fabrik Gmbh | Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| GB9720061D0 (en) | 1997-09-19 | 1997-11-19 | Crosfield Joseph & Sons | Metal compounds as phosphate binders |
| SE9704870D0 (sv) | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulation I |
| SE9704869D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulaton II |
| WO1999055157A1 (en) * | 1998-04-30 | 1999-11-04 | Sepracor Inc. | R-rabeprazole compositions and methods |
| CA2330324A1 (en) * | 1998-04-30 | 1999-11-04 | Sepracor Inc. | S-rabeprazole compositions and methods |
| JP4346243B2 (ja) | 1998-08-10 | 2009-10-21 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | プロトン・ポンプ・インヒビターのプロドラッグ |
| US6093734A (en) * | 1998-08-10 | 2000-07-25 | Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin | Prodrugs of proton pump inhibitors |
| DK1105105T3 (da) | 1998-08-12 | 2006-07-17 | Altana Pharma Ag | Oral administrationsform til pyridin-2-ylmethylsulfinyl-1H-benzimidazoler |
| US20050048077A1 (en) * | 2002-02-21 | 2005-03-03 | George Sachs | Compositions, test kits and methods for detecting helicobacter pylori |
| MY148805A (en) * | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
| US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| TWI372066B (en) | 2003-10-01 | 2012-09-11 | Wyeth Corp | Pantoprazole multiparticulate formulations |
| US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| JP5563735B2 (ja) | 2004-06-16 | 2014-07-30 | タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド | Ｐｐｉ多回剤形 |
| MY157620A (en) | 2006-01-31 | 2016-06-30 | Cytochroma Dev Inc | A granular material of a solid water-soluble mixed metal compound capable of binding phosphate |
| GB0714670D0 (en) | 2007-07-27 | 2007-09-05 | Ineos Healthcare Ltd | Use |
| GB0720220D0 (en) | 2007-10-16 | 2007-11-28 | Ineos Healthcare Ltd | Compound |
| GB0913525D0 (en) | 2009-08-03 | 2009-09-16 | Ineos Healthcare Ltd | Method |
| GB201001779D0 (en) | 2010-02-04 | 2010-03-24 | Ineos Healthcare Ltd | Composition |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2189699A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated acid-labile medicaments |
| US5330982A (en) * | 1986-12-17 | 1994-07-19 | Glaxo Group Limited | Pharmaceutical composition containing a 5-HT receptor antagonist and an H+ K+ Atpase inhibitor and a method of treating gastrointestingal disorders therewith |
| JPH08509736A (ja) * | 1993-04-27 | 1996-10-15 | セプラコー，インコーポレイテッド | 光学的に純粋な（−）パントプラゾールを用いる胃の疾患治療の方法と組成 |
| SE9402431D0 (sv) * | 1994-07-08 | 1994-07-08 | Astra Ab | New tablet formulation |
| DE29522419U1 (de) * | 1994-07-08 | 2003-07-03 | AstraZeneca AB, Södertälje | Tablettierte Mehrfacheinheits-Dosisform |
| US6132768A (en) * | 1995-07-05 | 2000-10-17 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Oral pharmaceutical composition with delayed release of active ingredient for reversible proton pump inhibitors |
| US5945124A (en) * | 1995-07-05 | 1999-08-31 | Byk Gulden Chemische Fabrik Gmbh | Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole |
-
1996
- 1996-06-20 SE SE9602442A patent/SE9602442D0/xx unknown
-
1997
- 1997-06-18 SK SK1655-98A patent/SK284204B6/sk not_active IP Right Cessation
- 1997-06-18 HU HU9901794A patent/HUP9901794A3/hu unknown
- 1997-06-18 ES ES97930933T patent/ES2208921T3/es not_active Expired - Lifetime
- 1997-06-18 PL PL97330910A patent/PL189716B1/pl not_active IP Right Cessation
- 1997-06-18 WO PCT/SE1997/001098 patent/WO1997048380A1/en active IP Right Grant
- 1997-06-18 TR TR1998/02647T patent/TR199802647T2/xx unknown
- 1997-06-18 UA UA99010150A patent/UA64715C2/uk unknown
- 1997-06-18 CZ CZ0420398A patent/CZ298213B6/cs not_active IP Right Cessation
- 1997-06-18 BR BR9709838A patent/BR9709838A/pt not_active Application Discontinuation
- 1997-06-18 NZ NZ332990A patent/NZ332990A/xx unknown
- 1997-06-18 US US08/945,425 patent/US20010008900A1/en not_active Abandoned
- 1997-06-18 DE DE69725860T patent/DE69725860T2/de not_active Expired - Fee Related
- 1997-06-18 RU RU99101081/14A patent/RU2203662C2/ru not_active IP Right Cessation
- 1997-06-18 JP JP10502822A patent/JP2000512993A/ja active Pending
- 1997-06-18 CA CA002257405A patent/CA2257405A1/en not_active Abandoned
- 1997-06-18 AU AU34690/97A patent/AU726859B2/en not_active Ceased
- 1997-06-18 PT PT97930933T patent/PT921787E/pt unknown
- 1997-06-18 AT AT97930933T patent/ATE252885T1/de not_active IP Right Cessation
- 1997-06-18 IL IL12754297A patent/IL127542A0/xx active IP Right Grant
- 1997-06-18 EE EE9800435A patent/EE04606B1/xx not_active IP Right Cessation
- 1997-06-18 EP EP97930933A patent/EP0921787B1/en not_active Expired - Lifetime
- 1997-06-18 CN CNB971955387A patent/CN1178648C/zh not_active Expired - Fee Related
- 1997-06-18 DK DK97930933T patent/DK0921787T3/da active
-
1998
- 1998-12-09 RS YUP-566/98A patent/RS49590B/sr unknown
- 1998-12-13 IL IL127542A patent/IL127542A/en not_active IP Right Cessation
- 1998-12-15 IS IS4923A patent/IS2216B/is unknown
- 1998-12-18 NO NO19985964A patent/NO323295B1/no not_active IP Right Cessation
-
1999
- 1999-08-06 HK HK99103406A patent/HK1018590A1/xx not_active IP Right Cessation
-
2004
- 2004-06-18 US US10/871,506 patent/US20050113418A1/en not_active Abandoned
-
2006
- 2006-10-05 US US11/544,956 patent/US20070276007A1/en not_active Abandoned
-
2008
- 2008-09-30 US US12/242,006 patent/US20090036494A1/en not_active Abandoned
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