HUP9901579A3 - Antibodies specific for alpha-d-integrin - Google Patents

Antibodies specific for alpha-d-integrin

Info

Publication number
HUP9901579A3
HUP9901579A3 HU9901579A HUP9901579A HUP9901579A3 HU P9901579 A3 HUP9901579 A3 HU P9901579A3 HU 9901579 A HU9901579 A HU 9901579A HU P9901579 A HUP9901579 A HU P9901579A HU P9901579 A3 HUP9901579 A3 HU P9901579A3
Authority
HU
Hungary
Prior art keywords
integrin
alpha
antibodies specific
antibodies
specific
Prior art date
Application number
HU9901579A
Other languages
English (en)
Original Assignee
Icos Corp Bothell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp Bothell filed Critical Icos Corp Bothell
Publication of HUP9901579A2 publication Critical patent/HUP9901579A2/hu
Publication of HUP9901579A3 publication Critical patent/HUP9901579A3/hu
Publication of HU223977B1 publication Critical patent/HU223977B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C07K14/70553—Integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HU9901579A 1996-02-22 1997-02-24 Alfa-d-integrin-re specifikus antitestek HU223977B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/605,672 US5817515A (en) 1993-12-23 1996-02-22 Human B2 integrin alpha subunit antibodies
PCT/US1997/002713 WO1997031099A1 (en) 1996-02-22 1997-02-24 Human beta 2 integrin alpha subunit

Publications (3)

Publication Number Publication Date
HUP9901579A2 HUP9901579A2 (hu) 1999-08-30
HUP9901579A3 true HUP9901579A3 (en) 2001-10-29
HU223977B1 HU223977B1 (hu) 2005-03-29

Family

ID=24424704

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901579A HU223977B1 (hu) 1996-02-22 1997-02-24 Alfa-d-integrin-re specifikus antitestek

Country Status (18)

Country Link
US (1) US5817515A (hu)
EP (1) EP0835301B1 (hu)
JP (1) JP2001526524A (hu)
CN (1) CN1103812C (hu)
AT (1) ATE293685T1 (hu)
AU (1) AU723110B2 (hu)
BR (1) BR9702101A (hu)
CA (1) CA2218755C (hu)
CZ (1) CZ287921B6 (hu)
DE (1) DE69733051D1 (hu)
FI (1) FI974018A (hu)
HU (1) HU223977B1 (hu)
IL (1) IL122011A (hu)
NO (1) NO318764B1 (hu)
PL (1) PL187013B1 (hu)
RU (1) RU2183671C2 (hu)
SK (1) SK283135B6 (hu)
WO (1) WO1997031099A1 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837478A (en) * 1993-12-23 1998-11-17 Icos Corporation Method of identifying modulators of binding between and VCAM-1
US6620915B2 (en) * 1993-12-23 2003-09-16 Icos Corporation Monoclonal antibodies specific for integrin α-d subunit
US20030055231A1 (en) * 1998-10-28 2003-03-20 Jian Ni 12 human secreted proteins
EP1267926A2 (en) 2000-03-17 2003-01-02 Millennium Pharmaceuticals, Inc. Method of inhibiting stenosis and restenosis with a mixture of antibodies anti cd18 and anti ccr2
WO2023235971A1 (en) * 2022-06-08 2023-12-14 The Regents Of The University Of California Antibodies and immunotherapies that target the active conformation of integrin beta 2

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271139A (en) * 1978-03-27 1981-06-02 Hiram Hart Scintillation proximity assay
US4568649A (en) * 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
WO1992006697A1 (en) * 1990-10-23 1992-04-30 Repligen Corporation Anti-inflammatory composition
JPH07502727A (ja) * 1991-10-01 1995-03-23 ザ・ジエネラル・ホスピタル・コーポレーシヨン 接着分子に対する抗体を用いた同種移植片拒絶の防止
JP3679112B2 (ja) * 1991-10-04 2005-08-03 アメリカ合衆国 細胞接着分子の遮断による眼の炎症の治療
US5470953A (en) * 1993-12-23 1995-11-28 Icos Corporation Human β2 integrin α subunit
EP0757697A4 (en) * 1994-04-12 2000-05-17 Boehringer Ingelheim Pharma USE OF AGENTS INHIBITING INTERCELLULAR INTERACTION IN THE TREATMENT OF VIRAL BREATH INFECTION

Also Published As

Publication number Publication date
NO974852D0 (no) 1997-10-21
JP2001526524A (ja) 2001-12-18
HU223977B1 (hu) 2005-03-29
SK283135B6 (sk) 2003-03-04
WO1997031099A1 (en) 1997-08-28
US5817515A (en) 1998-10-06
SK140997A3 (en) 1998-09-09
CN1189851A (zh) 1998-08-05
CA2218755A1 (en) 1997-08-28
PL187013B1 (pl) 2004-04-30
EP0835301A1 (en) 1998-04-15
PL323195A1 (en) 1998-03-16
AU723110B2 (en) 2000-08-17
EP0835301B1 (en) 2005-04-20
ATE293685T1 (de) 2005-05-15
BR9702101A (pt) 1999-07-20
NO974852L (no) 1997-12-19
AU2133397A (en) 1997-09-10
NO318764B1 (no) 2005-05-02
CA2218755C (en) 1999-08-31
FI974018A (fi) 1997-12-03
HUP9901579A2 (hu) 1999-08-30
FI974018A0 (fi) 1997-10-21
IL122011A0 (en) 1998-03-10
IL122011A (en) 2001-05-20
DE69733051D1 (de) 2005-05-25
CZ328697A3 (cs) 1998-07-15
CN1103812C (zh) 2003-03-26
RU2183671C2 (ru) 2002-06-20
CZ287921B6 (cs) 2001-03-14

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Legal Events

Date Code Title Description
HFG4 Patent granted, date of granting

Effective date: 20050218

MM4A Lapse of definitive patent protection due to non-payment of fees