HUP9901288A2 - LHRH-analógokat és antiösztrogéneket tartalmazó kombinációs gyógyszerkészítmények nőgyógyászati zavarok kezelésére - Google Patents
LHRH-analógokat és antiösztrogéneket tartalmazó kombinációs gyógyszerkészítmények nőgyógyászati zavarok kezeléséreInfo
- Publication number
- HUP9901288A2 HUP9901288A2 HU9901288A HUP9901288A HUP9901288A2 HU P9901288 A2 HUP9901288 A2 HU P9901288A2 HU 9901288 A HU9901288 A HU 9901288A HU P9901288 A HUP9901288 A HU P9901288A HU P9901288 A2 HUP9901288 A2 HU P9901288A2
- Authority
- HU
- Hungary
- Prior art keywords
- antiestrogens
- pharmaceutical preparation
- preparation containing
- combined pharmaceutical
- analogous substances
- Prior art date
Links
- 229940046836 anti-estrogen Drugs 0.000 title abstract 2
- 230000001833 anti-estrogenic effect Effects 0.000 title abstract 2
- 239000000328 estrogen antagonist Substances 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- XLXSAKCOAKORKW-UHFFFAOYSA-N gonadorelin Chemical class C1CCC(C(=O)NCC(N)=O)N1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C(CC=1NC=NC=1)NC(=O)C1NC(=O)CC1)CC1=CC=C(O)C=C1 XLXSAKCOAKORKW-UHFFFAOYSA-N 0.000 abstract 2
- 201000009273 Endometriosis Diseases 0.000 abstract 1
- 206010046798 Uterine leiomyoma Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 239000002434 gonadorelin derivative Substances 0.000 abstract 1
- 201000010260 leiomyoma Diseases 0.000 abstract 1
- XZEUAXYWNKYKPL-URLMMPGGSA-N ormeloxifene Chemical compound C1([C@@H]2[C@H](C3=CC=C(C=C3OC2(C)C)OC)C=2C=CC(OCCN3CCCC3)=CC=2)=CC=CC=C1 XZEUAXYWNKYKPL-URLMMPGGSA-N 0.000 abstract 1
- 229960003327 ormeloxifene Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A találmány tárgya egy LHRH-analóg vagy LHRH-analógők kőmbinációjánakés egy szövetszelektív ösztrőgén hatású antiösztőrgénnek - melyralőxifen, drőlőxifen, centchrőmán vagy ezek származéka - alkalmazásanőgyógyászati zavarők, különösen endőmetriősisők és miómák kezelésére. ŕ
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19604231A DE19604231A1 (de) | 1996-01-29 | 1996-01-29 | Pharmazeutisches Kombinationspräparat und seine Verwendung zur Behandlung von gynäkologischen Störungen |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9901288A2 true HUP9901288A2 (hu) | 1999-08-30 |
HUP9901288A3 HUP9901288A3 (en) | 2000-03-28 |
Family
ID=7784640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9901288A HUP9901288A3 (en) | 1996-01-29 | 1997-01-29 | Combined pharmaceutical preparation containing lhrh-analogous substances and antiestrogens for treating gynaecological disorders |
Country Status (20)
Country | Link |
---|---|
US (3) | US7309691B2 (hu) |
EP (1) | EP0877621A1 (hu) |
JP (1) | JP2000505422A (hu) |
KR (1) | KR19990082080A (hu) |
CN (1) | CN1209750A (hu) |
BG (1) | BG63248B1 (hu) |
BR (1) | BR9707210A (hu) |
CZ (1) | CZ239198A3 (hu) |
DE (1) | DE19604231A1 (hu) |
EA (1) | EA001178B1 (hu) |
HU (1) | HUP9901288A3 (hu) |
IL (1) | IL125557A0 (hu) |
MX (1) | MX9806082A (hu) |
NO (1) | NO983465L (hu) |
PL (1) | PL328066A1 (hu) |
SK (1) | SK98798A3 (hu) |
TR (1) | TR199801452T2 (hu) |
TW (1) | TW577735B (hu) |
WO (1) | WO1997027863A1 (hu) |
ZA (1) | ZA97741B (hu) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7105487B2 (en) | 2000-10-05 | 2006-09-12 | Veyx-Pharma Gmbh | Method for inducing onset of the reproductive cycle of female breeding animals |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6828415B2 (en) * | 1993-02-19 | 2004-12-07 | Zentaris Gmbh | Oligopeptide lyophilisate, their preparation and use |
US6096764A (en) * | 1997-08-21 | 2000-08-01 | Eli Lilly And Company | Methods for inhibiting detrimental side-effects due to GnRH of GnRH agonist administration |
DE69912422T2 (de) * | 1998-04-23 | 2004-08-19 | Zentaris Gmbh | Methode zur behandlung von fruchtbarkeitsstörungen |
PT1229906E (pt) * | 1999-08-31 | 2008-01-18 | Bayer Schering Pharma Ag | Mesoprogestinas para o tratamento e prevenção de distúrbios ginecológicos hormonodependentes benignos |
US8193252B1 (en) | 1999-08-31 | 2012-06-05 | Bayer Pharma AG | Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders |
US7005418B1 (en) | 1999-09-23 | 2006-02-28 | Zentaris Gmbh | Method for the therapeutic management of extrauterine proliferation of endometrial tissue, chronic pelvic pain and fallopian tube obstruction |
NZ534836A (en) * | 1999-09-23 | 2007-07-27 | Zentaris Gmbh | Method for the therapeutic management of extrauterine proliferatoin of endometrial tissue, chronic pelvic pain and fallopian tube obstruction |
AU2001269439A1 (en) * | 2000-07-05 | 2002-01-14 | Takeda Chemical Industries Ltd. | Medicinal preparations for treating sex hormone-dependent diseases |
IL145838A (en) * | 2000-10-16 | 2008-11-03 | Pfizer Prod Inc | Use of an estrogen agonist / antagonist to produce a drug for the treatment of vaginitis |
WO2002056903A2 (en) * | 2001-01-17 | 2002-07-25 | Praecis Pharmaceuticals Inc. | Methods for treating hormone associated conditions using a combination of lhrh antagonists and specific estrogen receptor modulators |
JP2003137814A (ja) * | 2001-08-10 | 2003-05-14 | Takeda Chem Ind Ltd | GnRHアゴニストの併用剤 |
US7705011B2 (en) | 2005-03-16 | 2010-04-27 | Masao Igarashi | Agent for treatment and prevention of endometriosos and uterine adenomyosis |
EP2266567A1 (en) | 2009-05-26 | 2010-12-29 | Æterna Zentaris GmbH | Use of cetrorelix in combination with PDE V inhibitors for the treatment of sex hormone dependent disorders |
EP2266568A1 (en) | 2009-05-26 | 2010-12-29 | Æterna Zentaris GmbH | Use of LHRH antagonists in combination with PDE V inhibitors for the treatment of sex hormone dependent disorders |
BR112012032189B1 (pt) * | 2010-06-16 | 2020-11-03 | Endorecherche, Inc | usos de um agonista ou antagonista de lhrh em associação com um modulador de receptor de estrogênio seletivo e com um precursor de esteróide sexual para a preparação de uma medicamento para o tratamento ou prevenção de doenças relacionadas com estrogênio e kits |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5395842A (en) * | 1988-10-31 | 1995-03-07 | Endorecherche Inc. | Anti-estrogenic compounds and compositions |
US5457116A (en) * | 1993-10-15 | 1995-10-10 | Eli Lilly And Company | Methods of inhibiting uterine fibrosis |
US5451589A (en) * | 1993-12-21 | 1995-09-19 | Eli Lilly And Company | Methods of inhibiting ovarian dysgenesis, delayed puberty, or sexual infantilism |
US5451590A (en) * | 1993-12-21 | 1995-09-19 | Eli Lilly & Co. | Methods of inhibiting sexual precocity |
US5593987A (en) * | 1993-12-21 | 1997-01-14 | Eli Lilly And Company | Methods of inhibiting breast disorders |
US6096764A (en) * | 1997-08-21 | 2000-08-01 | Eli Lilly And Company | Methods for inhibiting detrimental side-effects due to GnRH of GnRH agonist administration |
-
1996
- 1996-01-29 DE DE19604231A patent/DE19604231A1/de not_active Ceased
-
1997
- 1997-01-29 BR BR9707210A patent/BR9707210A/pt not_active IP Right Cessation
- 1997-01-29 IL IL12555797A patent/IL125557A0/xx unknown
- 1997-01-29 JP JP9527295A patent/JP2000505422A/ja not_active Ceased
- 1997-01-29 HU HU9901288A patent/HUP9901288A3/hu unknown
- 1997-01-29 PL PL97328066A patent/PL328066A1/xx unknown
- 1997-01-29 ZA ZA9700741A patent/ZA97741B/xx unknown
- 1997-01-29 CN CN97191940A patent/CN1209750A/zh active Pending
- 1997-01-29 SK SK987-98A patent/SK98798A3/sk unknown
- 1997-01-29 EA EA199800666A patent/EA001178B1/ru not_active IP Right Cessation
- 1997-01-29 KR KR1019980705802A patent/KR19990082080A/ko not_active Application Discontinuation
- 1997-01-29 US US09/117,357 patent/US7309691B2/en not_active Expired - Fee Related
- 1997-01-29 TR TR1998/01452T patent/TR199801452T2/xx unknown
- 1997-01-29 WO PCT/EP1997/000395 patent/WO1997027863A1/de not_active Application Discontinuation
- 1997-01-29 EP EP97902258A patent/EP0877621A1/de not_active Withdrawn
- 1997-01-29 CZ CZ982391A patent/CZ239198A3/cs unknown
- 1997-02-14 TW TW086101753A patent/TW577735B/zh active
-
1998
- 1998-07-28 NO NO983465A patent/NO983465L/no not_active Application Discontinuation
- 1998-07-29 BG BG102660A patent/BG63248B1/bg unknown
- 1998-07-29 MX MX9806082A patent/MX9806082A/es unknown
-
2001
- 2001-08-10 US US09/925,419 patent/US20020032156A1/en not_active Abandoned
-
2002
- 2002-07-31 US US10/207,907 patent/US20020198155A1/en not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7105487B2 (en) | 2000-10-05 | 2006-09-12 | Veyx-Pharma Gmbh | Method for inducing onset of the reproductive cycle of female breeding animals |
Also Published As
Publication number | Publication date |
---|---|
CN1209750A (zh) | 1999-03-03 |
ZA97741B (en) | 1997-07-30 |
US20010041672A1 (en) | 2001-11-15 |
TW577735B (en) | 2004-03-01 |
BR9707210A (pt) | 1999-04-06 |
US20020032156A1 (en) | 2002-03-14 |
NO983465L (no) | 1998-09-18 |
SK98798A3 (en) | 1999-03-12 |
BG63248B1 (bg) | 2001-07-31 |
IL125557A0 (en) | 1999-03-12 |
PL328066A1 (en) | 1999-01-04 |
NO983465D0 (no) | 1998-07-28 |
TR199801452T2 (xx) | 1998-10-21 |
EA199800666A1 (ru) | 1999-02-25 |
BG102660A (en) | 1999-06-30 |
JP2000505422A (ja) | 2000-05-09 |
CZ239198A3 (cs) | 1998-11-11 |
KR19990082080A (ko) | 1999-11-15 |
WO1997027863A1 (de) | 1997-08-07 |
US20020198155A1 (en) | 2002-12-26 |
EP0877621A1 (de) | 1998-11-18 |
MX9806082A (es) | 1998-10-31 |
EA001178B1 (ru) | 2000-10-30 |
HUP9901288A3 (en) | 2000-03-28 |
US7309691B2 (en) | 2007-12-18 |
DE19604231A1 (de) | 1997-07-31 |
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