DE69739758D1 - Vakzine zur behandlung von lymphomen und leukämie - Google Patents
Vakzine zur behandlung von lymphomen und leukämieInfo
- Publication number
- DE69739758D1 DE69739758D1 DE69739758T DE69739758T DE69739758D1 DE 69739758 D1 DE69739758 D1 DE 69739758D1 DE 69739758 T DE69739758 T DE 69739758T DE 69739758 T DE69739758 T DE 69739758T DE 69739758 D1 DE69739758 D1 DE 69739758D1
- Authority
- DE
- Germany
- Prior art keywords
- lymphoma
- vaccine
- leukemia
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010025323 Lymphomas Diseases 0.000 title 1
- 208000032839 leukemia Diseases 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0026—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
- C12N9/0028—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)
- C12N9/003—Dihydrofolate reductase [DHFR] (1.5.1.3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/644,664 US5776746A (en) | 1996-05-01 | 1996-05-01 | Gene amplification methods |
US08/761,277 US5972334A (en) | 1996-05-01 | 1996-12-06 | Vaccines for treatment of lymphoma and leukemia |
PCT/US1997/007039 WO1997041244A1 (en) | 1996-05-01 | 1997-04-25 | Vaccines for treatment of lymphoma and leukemia |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69739758D1 true DE69739758D1 (de) | 2010-03-25 |
Family
ID=24585869
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69739758T Expired - Lifetime DE69739758D1 (de) | 1996-05-01 | 1997-04-25 | Vakzine zur behandlung von lymphomen und leukämie |
Country Status (4)
Country | Link |
---|---|
US (5) | US5776746A (de) |
DE (1) | DE69739758D1 (de) |
TW (1) | TW200519125A (de) |
ZA (1) | ZA973701B (de) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999041403A1 (en) * | 1998-02-12 | 1999-08-19 | The Regents Of The University Of California | Compositions for receptor/liposome mediated transfection and methods of using same |
US6867154B1 (en) | 1998-04-20 | 2005-03-15 | Southern Mills, Inc. | Patterned, flame resistant fabrics and method for making same |
ID28040A (id) * | 1998-05-19 | 2001-05-03 | Avidex Ltd | Reseptor sel t yang dapat larut |
US6156514A (en) | 1998-12-03 | 2000-12-05 | Sunol Molecular Corporation | Methods for making recombinant cells |
ATE417106T1 (de) * | 1999-03-12 | 2008-12-15 | Aventis Pasteur | Chlamydia antigene und deren korrespondierende dna fragmente und verwendungen davon |
EP1192278A4 (de) * | 1999-06-11 | 2003-05-28 | Human Genome Sciences Inc | 48 menschliche sekretierte proteine |
US20060276629A9 (en) * | 1999-12-17 | 2006-12-07 | Hildebrand William H | Purification and characterization of soluble human HLA proteins |
US7521202B2 (en) * | 1999-12-17 | 2009-04-21 | The Board Of Regents Of The University Of Oklahoma | Method and apparatus for the production of soluble MHC antigens and uses thereof |
US20030166057A1 (en) * | 1999-12-17 | 2003-09-04 | Hildebrand William H. | Method and apparatus for the production of soluble MHC antigens and uses thereof |
US20060035338A1 (en) * | 1999-12-17 | 2006-02-16 | Pure Protein Llc | Method and apparatus for the production of soluble MHC antigens and uses thereof |
WO2002013861A2 (en) * | 2000-08-11 | 2002-02-21 | Favrille, Inc. | Method and composition for altering a t cell mediated pathology |
ES2401421T3 (es) * | 2000-08-11 | 2013-04-19 | Mmrgolbal, Inc. | Método y ocmposición para alterar una patología mediada por células B |
US6911204B2 (en) | 2000-08-11 | 2005-06-28 | Favrille, Inc. | Method and composition for altering a B cell mediated pathology |
US20030130215A1 (en) * | 2000-09-21 | 2003-07-10 | Ryan James W. | Isolated genomic polynucleotide fragments from chromosome 7 |
WO2002030964A2 (en) * | 2000-10-10 | 2002-04-18 | The Board Of Regents Of The University Of Oklahoma | Comparative ligand mapping from mhc positive cells |
US20070099182A1 (en) * | 2000-10-10 | 2007-05-03 | Hildebrand William H | Comparative ligand mapping from MHC class I positive cells |
US20050003483A1 (en) * | 2000-10-10 | 2005-01-06 | Hildebrand William H. | Comparative ligand mapping from MHC class 1 positive cells |
US20090062512A1 (en) * | 2000-10-10 | 2009-03-05 | Hildebrand William H | Comparative ligand mapping from MHC class I positive cells |
US20070026433A1 (en) | 2001-03-09 | 2007-02-01 | Hildebrand William H | Epitope testing using soluble HLA |
US20020122820A1 (en) * | 2001-01-16 | 2002-09-05 | Hildebrand William H. | Soluble MHC artificial antigen presenting cells |
WO2002069198A2 (en) * | 2001-02-21 | 2002-09-06 | The Board Of Regents Of The University Of Oklahoma | Hla ligand database utilizing predictive algorithms and methods of making and using same |
DE60223040T2 (de) * | 2001-03-09 | 2008-07-31 | The Board Of Regents Of The University Of Oklahoma, Norman | Epitop-untersuchung mit hla |
US20040126829A1 (en) * | 2001-12-18 | 2004-07-01 | Hildebrand William H. | Anti-HLA assay and methods |
WO2003062449A2 (en) * | 2002-01-18 | 2003-07-31 | The Trustees Of Columbia University In The City Of New York | Methods of isolating specific cells of caenorhabditis elegans and obtaining genomic information therefrom |
AU2003237493A1 (en) * | 2002-01-23 | 2003-09-02 | Cel-Sci Corporation | Methods for treating diseases or conditions with peptide constructs |
EP1531850B1 (de) * | 2002-06-07 | 2012-02-22 | ZymoGenetics, Inc. | Verwendung von IL-21 und monoklonalem Antikörper zur Behandlung von fester Tumore |
ATE382687T1 (de) * | 2003-01-16 | 2008-01-15 | Genencor Int | Verfahren zur stellengerichteten mutagenese und gezielten randomisierung |
KR100643122B1 (ko) * | 2003-03-03 | 2006-11-10 | 주식회사 에스엔피 제네틱스 | Hbv진행/hcc발생에 대한 감수성의 예측을 위한il10 해플로타입의 용도 |
AU2004234377A1 (en) * | 2003-04-25 | 2004-11-11 | Immunex Corporation | Inducers of recombinant protein expression |
US20040259135A1 (en) * | 2003-05-09 | 2004-12-23 | Cleary Michael D. | Biosynthetic labeling and separation of RNA |
US7696322B2 (en) * | 2003-07-28 | 2010-04-13 | Catalent Pharma Solutions, Inc. | Fusion antibodies |
WO2005030931A2 (en) * | 2003-09-23 | 2005-04-07 | Favrille, Inc. | Altering a b cell pathology using self-derived antigens in conjunction with specific-binding cytoreductive agent |
WO2005044998A2 (en) * | 2003-11-05 | 2005-05-19 | Palingen, Inc. | Enhanced b cell cytotoxicity of cdim binding antibody |
US20050130897A1 (en) * | 2003-12-11 | 2005-06-16 | Ma Jian-Xing | Compounds useful in inhibiting vascular leakage, inflammation and fibrosis and methods of making and using same |
US7906180B2 (en) * | 2004-02-27 | 2011-03-15 | Molecular Imprints, Inc. | Composition for an etching mask comprising a silicon-containing material |
US7858323B2 (en) | 2004-06-09 | 2010-12-28 | The Regents Of The University Of Michigan | Phage microarray profiling of the humoral response to disease |
ES2732623T3 (es) | 2005-01-06 | 2019-11-25 | Innate Pharma Sa | Tratamientos y métodos de combinación anti-KIR |
US7790446B2 (en) * | 2005-02-11 | 2010-09-07 | Kosagen Cell Factory Oü | Vectors, cell lines and their use in obtaining extended episomal maintenance replication of hybrid plasmids and expression of gene products |
WO2008088301A2 (en) * | 2005-04-26 | 2008-07-24 | Corgentech, Inc. | Inhibitors of dnaa activity |
RU2295517C1 (ru) * | 2005-06-24 | 2007-03-20 | Институт проблем химической физики РАН (ИПХФ РАН) | Производные дикарбоновых кислот, ингибиторы метастазов и средства, повышающие химиотерапевтическую активность противоопухолевых препаратов, способ усиления эффективности цитостатиков, способ ингибирования процесса метастазирования |
US20070134249A1 (en) * | 2005-12-08 | 2007-06-14 | Genitope Corporation | Combination therapy and antibody panels |
ES2902063T3 (es) | 2006-09-08 | 2022-03-24 | Abbvie Bahamas Ltd | Proteínas de unión a interleucina-13 |
WO2008051619A2 (en) * | 2006-10-24 | 2008-05-02 | Los Alamos National Security, Llc | Vectors and methods for selecting open reading frames |
EP1953222A1 (de) * | 2007-01-24 | 2008-08-06 | Boehringer Ingelheim Pharma GmbH & Co. KG | Verbesserung des Zellwachstums |
AR072832A1 (es) * | 2008-07-23 | 2010-09-22 | Boehringer Ingelheim Pharma | LINEAS DE CELULAS HOSPEDANTES DE PRODUCCION MEJORADA QUE CONTIENEN CONSTRUCCIONES DE VECTORES QUE COMPRENDEN UN CASETE DE EXPRESIoN DE DHFR (ENZIMA DIHIDROFOLATO REDUCTASA). |
US9782565B2 (en) | 2008-10-01 | 2017-10-10 | Covidien Lp | Endoscopic ultrasound-guided biliary access system |
US8968210B2 (en) | 2008-10-01 | 2015-03-03 | Covidien LLP | Device for needle biopsy with integrated needle protection |
US11298113B2 (en) | 2008-10-01 | 2022-04-12 | Covidien Lp | Device for needle biopsy with integrated needle protection |
US9186128B2 (en) | 2008-10-01 | 2015-11-17 | Covidien Lp | Needle biopsy device |
US9332973B2 (en) | 2008-10-01 | 2016-05-10 | Covidien Lp | Needle biopsy device with exchangeable needle and integrated needle protection |
WO2010053518A2 (en) * | 2008-10-29 | 2010-05-14 | Sangamo Biosciences, Inc. | Methods and compositions for inactivating glutamine synthetase gene expression |
WO2011003633A1 (en) | 2009-07-06 | 2011-01-13 | Alize Pharma Ii | Pegylated l-asparaginase |
EP2548025A4 (de) | 2010-03-17 | 2013-09-25 | Univ Michigan | Verwendung von phagenepitopen zur profilierung einer immunreaktion |
WO2014036488A1 (en) | 2012-08-31 | 2014-03-06 | Biovest International, Inc. | Methods for producing high-fidelity autologous idiotype vaccines |
US10857219B2 (en) | 2014-03-28 | 2020-12-08 | The Board Of Regents Of The University Of Oklahoma | Compositions comprising soluble HLA/M. tuberculosis-specific ligand complexes and methods of production and use thereof |
US10174302B1 (en) | 2017-06-21 | 2019-01-08 | Xl-Protein Gmbh | Modified L-asparaginase |
CA3135175C (en) | 2019-03-28 | 2022-10-18 | Southern Mills, Inc. | Flame resistant fabrics |
US11891731B2 (en) | 2021-08-10 | 2024-02-06 | Southern Mills, Inc. | Flame resistant fabrics |
WO2023168397A1 (en) * | 2022-03-04 | 2023-09-07 | Sigma-Aldrich Co. Llc | Metabolic selection via the asparagine biosynthesis pathway |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4634665A (en) * | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US5179017A (en) * | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4399216A (en) * | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4656134A (en) * | 1982-01-11 | 1987-04-07 | Board Of Trustees Of Leland Stanford Jr. University | Gene amplification in eukaryotic cells |
US4965188A (en) * | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
GB8601597D0 (en) * | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
FR2619719B1 (fr) | 1987-09-01 | 1991-05-10 | Sanofi Sa | Procede d'obtention d'interleukine-2 a partir de cellules eucaryotes, vecteurs necessaires a sa mise en oeuvre et lignees cellulaires hautement productrices |
US4956288A (en) | 1988-04-22 | 1990-09-11 | Biogen, Inc. | Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA |
US5043270A (en) * | 1989-03-31 | 1991-08-27 | The Board Of Trustees Of The Leland Stanford Junior University | Intronic overexpression vectors |
US5270202A (en) * | 1989-11-03 | 1993-12-14 | Syamal Raychaudhuri | Anti-idiotypic antibodies to human melanoma-associated proteoglycan antigen |
EP0433900B1 (de) | 1989-12-13 | 1995-09-20 | Yeda Research And Development Company Limited | Expression des rekombinanten Tumor-Nekrosisfaktor-Bindungsproteins I (TBP-I) |
US20030072751A1 (en) * | 1990-03-14 | 2003-04-17 | Heribert Bohlen | Idiotypic vaccination against b cell lymphoma |
WO1994008601A1 (en) * | 1992-10-14 | 1994-04-28 | The Board Of Trustees Of The Leland Stanford Junior University | Enhancement of b cell lymphoma tumor resistance using idiotype/cytokine conjugates |
US6235280B1 (en) * | 1996-04-12 | 2001-05-22 | Malaya Chatterjee | Methods of delaying development of CEA-associated tumors using anti-idiotype antibody 3H1 |
US6632431B2 (en) * | 2000-05-16 | 2003-10-14 | New York University | Anti-idiotypic antibody against FimH adhesion of uropathogenic type I-fimbriated Escherichia coli, compositions containing same and method for using same |
-
1996
- 1996-05-01 US US08/644,664 patent/US5776746A/en not_active Expired - Lifetime
- 1996-12-06 US US08/761,277 patent/US5972334A/en not_active Expired - Lifetime
-
1997
- 1997-04-25 DE DE69739758T patent/DE69739758D1/de not_active Expired - Lifetime
- 1997-04-29 ZA ZA9703701A patent/ZA973701B/xx unknown
- 1997-04-30 TW TW094104434A patent/TW200519125A/zh unknown
-
1999
- 1999-08-09 US US09/370,453 patent/US7419660B1/en not_active Expired - Fee Related
-
2001
- 2001-08-09 US US09/925,192 patent/US7405060B2/en not_active Expired - Fee Related
- 2001-08-09 US US09/925,664 patent/US7208146B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5776746A (en) | 1998-07-07 |
ZA973701B (en) | 1998-02-04 |
US5972334A (en) | 1999-10-26 |
US7208146B2 (en) | 2007-04-24 |
US20020160006A1 (en) | 2002-10-31 |
US7405060B2 (en) | 2008-07-29 |
TW200519125A (en) | 2005-06-16 |
US20040096452A1 (en) | 2004-05-20 |
US7419660B1 (en) | 2008-09-02 |
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