HUP9802762A2 - Difenil-metilén-piperidin-származékok, e vegyületeket tartalmazó gyógyászati készítmények, eljárás előállításukra és alkalmazásuk - Google Patents

Difenil-metilén-piperidin-származékok, e vegyületeket tartalmazó gyógyászati készítmények, eljárás előállításukra és alkalmazásuk

Info

Publication number
HUP9802762A2
HUP9802762A2 HU9802762A HUP9802762A HUP9802762A2 HU P9802762 A2 HUP9802762 A2 HU P9802762A2 HU 9802762 A HU9802762 A HU 9802762A HU P9802762 A HUP9802762 A HU P9802762A HU P9802762 A2 HUP9802762 A2 HU P9802762A2
Authority
HU
Hungary
Prior art keywords
producing
pharmaceutical compositions
compositions containing
piperidine derivatives
diphenylmethylene piperidine
Prior art date
Application number
HU9802762A
Other languages
English (en)
Inventor
David Robert Jaap
Duncan Robertson Rae
Original Assignee
Akzo Nobel N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel N.V. filed Critical Akzo Nobel N.V.
Publication of HUP9802762A2 publication Critical patent/HUP9802762A2/hu
Publication of HUP9802762A3 publication Critical patent/HUP9802762A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Abstract

A találmány tárgya az (I) általánős képletű difenil-metilén-piperidin-származék, a képletben n értéke 1 vagy 2, vagy gyógyászatilagelfőgadható sója. A találmány kiterjed az (I) általánős képletűvegyületeket tartalmazó gyógyszerkészítményekre, tővábbá a vegyületekelőállítására, valamint ezek alkalmazására pszichőtikűsrendellenességek kezelésére vagy megelőzésére. (I) ŕ
HU9802762A 1995-07-12 1996-07-09 Diphenylmethylene piperidine derivatives, pharmaceutical compositions containing them, process for producing them and their use HUP9802762A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95201910 1995-07-12

Publications (2)

Publication Number Publication Date
HUP9802762A2 true HUP9802762A2 (hu) 1999-10-28
HUP9802762A3 HUP9802762A3 (en) 2002-10-28

Family

ID=8220478

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9802762A HUP9802762A3 (en) 1995-07-12 1996-07-09 Diphenylmethylene piperidine derivatives, pharmaceutical compositions containing them, process for producing them and their use

Country Status (27)

Country Link
US (1) US5935974A (hu)
EP (1) EP0842170B1 (hu)
JP (1) JPH11508907A (hu)
KR (1) KR19990028807A (hu)
CN (1) CN1091108C (hu)
AR (1) AR003966A1 (hu)
AT (1) ATE199150T1 (hu)
AU (1) AU699370B2 (hu)
BR (1) BR9609330A (hu)
CA (1) CA2226851A1 (hu)
CZ (1) CZ288909B6 (hu)
DE (1) DE69611788T2 (hu)
DK (1) DK0842170T3 (hu)
ES (1) ES2156287T3 (hu)
GR (1) GR3035849T3 (hu)
HK (1) HK1010818A1 (hu)
HU (1) HUP9802762A3 (hu)
IL (1) IL118768A (hu)
NO (1) NO309765B1 (hu)
NZ (1) NZ315318A (hu)
PL (1) PL183837B1 (hu)
PT (1) PT842170E (hu)
RU (1) RU2162846C2 (hu)
TR (1) TR199800027T1 (hu)
TW (1) TW419477B (hu)
WO (1) WO1997003065A1 (hu)
ZA (1) ZA965691B (hu)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001519430A (ja) 1997-10-07 2001-10-23 アクゾ・ノベル・エヌ・ベー 抗精神病置換ピペリジン誘導体
AU2279099A (en) * 1998-01-09 1999-07-26 Akzo Nobel N.V. Use of diphenylmethylene piperidine derivatives in the manufacture of a medicament for the treatment of depression
WO1999034799A1 (en) * 1998-01-09 1999-07-15 Akzo Nobel N.V. Use of diphenylmethylene piperidine derivatives in the manufacture of a medicament for the treatment of movement disorders
US6358979B1 (en) 1999-06-11 2002-03-19 Merck & Co., Inc. N-cyclopentyl modulators of chemokine receptor activity
WO2000076514A1 (en) 1999-06-11 2000-12-21 Merck & Co., Inc. Cyclopentyl modulators of chemokine receptor activity
WO2000076973A1 (en) * 1999-06-11 2000-12-21 Merck & Co., Inc. N-cyclopentyl modulators of chemokine receptor activity
US6500844B1 (en) 1999-06-11 2002-12-31 Merck & Co., Inc. Cyclopentyl modulators of chemokine receptor activity
WO2000076513A1 (en) 1999-06-11 2000-12-21 Merck & Co., Inc. Cyclopentyl modulators of chemokine receptor activity
WO2000076511A1 (en) 1999-06-11 2000-12-21 Merck & Co., Inc. Cyclopentyl modulators of chemokine receptor activity
KR20010113007A (ko) * 2000-06-15 2001-12-24 주정호 항암제로서 유용한 ｎ-치환된 피페리디닐우레아 유도체 및그의 제조방법
TW200303304A (en) * 2002-02-18 2003-09-01 Astrazeneca Ab Chemical compounds
US6770659B2 (en) * 2002-08-26 2004-08-03 Sk Corporation Benzoyl piperidine compounds
MXPA05006427A (es) * 2002-12-18 2005-09-08 Fmc Corp Piperidinas y piridinas (arilmetilo sustituido)-n-4-(metilo disustituido).
SE0400208D0 (sv) * 2004-02-02 2004-02-02 Astrazeneca Ab Chemical compounds
TW200812582A (en) * 2006-04-06 2008-03-16 Astrazeneca Ab Medicaments
AU2015308437C1 (en) 2014-08-28 2020-11-05 Asceneuron Sa Glycosidase inhibitors
EP3389658B1 (en) 2015-12-18 2020-11-25 Merck Sharp & Dohme Corp. Glycosidase inhibitors and uses thereof
US11261183B2 (en) 2016-02-25 2022-03-01 Asceneuron Sa Sulfoximine glycosidase inhibitors
MA43680A (fr) 2016-02-25 2018-11-28 Asceneuron Sa Inhibiteurs de glycosidases
EA201891438A1 (ru) 2016-02-25 2019-01-31 Асенейрон С. А. Кислотно-аддитивные соли производных пиперазина
MX2018010192A (es) 2016-02-25 2019-01-31 Asceneuron S A Inhibidores de glucosidasa.
EP3672959A1 (en) 2017-08-24 2020-07-01 Asceneuron SA Linear glycosidase inhibitors
US11731972B2 (en) 2018-08-22 2023-08-22 Asceneuron Sa Spiro compounds as glycosidase inhibitors
US11795165B2 (en) 2018-08-22 2023-10-24 Asceneuron Sa Tetrahydro-benzoazepine glycosidase inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US450780A (en) * 1891-04-21 Steam-engine
US4180583A (en) * 1972-01-28 1979-12-25 Richardson-Merrell Inc. Olefinic 4-substituted piperidino derivatives as therapeutics
US3922276A (en) * 1974-12-11 1975-11-25 Robins Co Inc A H 1-Substituted-4-benzylidenepiperidines
US4540780A (en) * 1983-06-02 1985-09-10 Warner-Lambert Company Diphenylmethylene piperidines
US4666905A (en) * 1983-06-02 1987-05-19 Warner-Lambert Company Diphenylmethylene piperidines compositions and methods for their use

Also Published As

Publication number Publication date
AU6699396A (en) 1997-02-10
DE69611788T2 (de) 2001-08-02
IL118768A (en) 2000-10-31
EP0842170B1 (en) 2001-02-14
NO309765B1 (no) 2001-03-26
HK1010818A1 (en) 1999-07-02
NZ315318A (en) 1999-10-28
CZ8398A3 (cs) 1998-06-17
AU699370B2 (en) 1998-12-03
KR19990028807A (ko) 1999-04-15
ZA965691B (en) 1997-01-24
PL183837B1 (pl) 2002-07-31
EP0842170A1 (en) 1998-05-20
CA2226851A1 (en) 1997-01-30
MX9800368A (es) 1998-03-31
WO1997003065A1 (en) 1997-01-30
BR9609330A (pt) 1999-05-25
AR003966A1 (es) 1998-09-30
US5935974A (en) 1999-08-10
CN1091108C (zh) 2002-09-18
GR3035849T3 (en) 2001-08-31
PL324451A1 (en) 1998-05-25
NO980109D0 (no) 1998-01-09
ATE199150T1 (de) 2001-02-15
DE69611788D1 (de) 2001-03-22
RU2162846C2 (ru) 2001-02-10
TW419477B (en) 2001-01-21
HUP9802762A3 (en) 2002-10-28
TR199800027T1 (xx) 1998-05-21
PT842170E (pt) 2001-06-29
JPH11508907A (ja) 1999-08-03
IL118768A0 (en) 1996-10-31
CZ288909B6 (cs) 2001-09-12
DK0842170T3 (da) 2001-06-18
NO980109L (no) 1998-01-09
CN1190965A (zh) 1998-08-19
ES2156287T3 (es) 2001-06-16

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