HUP9802605A2 - 1,2,4-Benzotriazin-oxid-származékokat tartalmazó orális adagolású gélkapszula gyógyszerkészítmények - Google Patents

1,2,4-Benzotriazin-oxid-származékokat tartalmazó orális adagolású gélkapszula gyógyszerkészítmények

Info

Publication number
HUP9802605A2
HUP9802605A2 HU9802605A HUP9802605A HUP9802605A2 HU P9802605 A2 HUP9802605 A2 HU P9802605A2 HU 9802605 A HU9802605 A HU 9802605A HU P9802605 A HUP9802605 A HU P9802605A HU P9802605 A2 HUP9802605 A2 HU P9802605A2
Authority
HU
Hungary
Prior art keywords
pharmaceutical compositions
compositions containing
capsule formulation
gel capsule
oral gel
Prior art date
Application number
HU9802605A
Other languages
English (en)
Inventor
Ross Blundell
Stephen Brown
Original Assignee
Sanofi-Synthelabo Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo Inc. filed Critical Sanofi-Synthelabo Inc.
Publication of HUP9802605A2 publication Critical patent/HUP9802605A2/hu
Publication of HUP9802605A3 publication Critical patent/HUP9802605A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány zselatinkapszűla gyógyszerkészítményekre vőnatkőzik,amelyek hatóanyagként (I) általánős képletű vegyületet tartalmaznak,kókűszdióőlaj vagy szójababőlaj hőrdőzóanyag, tővábbáviszkőzitásmódősító és gyógyszerészetileg elfőgadható felületaktívanyag mellett. A találmány szerinti előnyös vegyület a 3-aminő-1,2,4-benzőtriazin(tirapazamin). A találmány szerinti készítmények rákős daganatők kezelésérealkalmasak. ŕ
HU9802605A 1995-09-12 1996-08-21 Pharmaceutical compositions containing oral gel capsule formulation of 1,2,4-benzotriazine oxides HUP9802605A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/527,233 US5597582A (en) 1995-09-12 1995-09-12 Oral gel capsule formulation of 1,2,4-benzotriazine oxides

Publications (2)

Publication Number Publication Date
HUP9802605A2 true HUP9802605A2 (hu) 1999-04-28
HUP9802605A3 HUP9802605A3 (en) 2000-02-28

Family

ID=24100665

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9802605A HUP9802605A3 (en) 1995-09-12 1996-08-21 Pharmaceutical compositions containing oral gel capsule formulation of 1,2,4-benzotriazine oxides

Country Status (19)

Country Link
US (1) US5597582A (hu)
EP (1) EP0868174B1 (hu)
JP (1) JPH11513365A (hu)
KR (1) KR100475388B1 (hu)
CN (1) CN1080113C (hu)
AT (1) ATE227982T1 (hu)
AU (1) AU702550B2 (hu)
CA (1) CA2231545C (hu)
CZ (1) CZ289733B6 (hu)
DE (1) DE69624935T2 (hu)
DK (1) DK0868174T3 (hu)
ES (1) ES2187668T3 (hu)
HK (1) HK1016889A1 (hu)
HU (1) HUP9802605A3 (hu)
MX (1) MX9801930A (hu)
NO (1) NO320019B1 (hu)
NZ (1) NZ315964A (hu)
PT (1) PT868174E (hu)
WO (1) WO1997009968A1 (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5484612A (en) * 1993-09-22 1996-01-16 The Board Of Trustees Of The Leland Stanford Junior University Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin
US6365181B1 (en) 2000-04-20 2002-04-02 Gattefosse Corporation Thixatropic gelatin carrier composition
CA2456569A1 (en) * 2003-03-14 2004-09-14 Auckland Uniservices Limited Benzoazine mono-n-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments
US8642079B2 (en) * 2004-02-23 2014-02-04 Hormos Medical Corporation Solid formulations of ospemifene
PT2275098E (pt) * 2004-05-04 2012-08-29 Hormos Medical Ltd Novas formulações orais de ospemifeno
US8758821B2 (en) * 2004-05-04 2014-06-24 Hormos Medical Ltd. Oral formulations of ospemifene
CN104705772B (zh) * 2015-01-28 2016-09-14 汤臣倍健股份有限公司 一种改善软胶囊漏油的生产工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60239418A (ja) * 1984-05-15 1985-11-28 Nippon Kayaku Co Ltd エトポシド軟カプセル製剤
US5175287A (en) * 1986-09-25 1992-12-29 S R I International Process for preparing 1,2,4-benzotriazine oxides
DE4322826A1 (de) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmazeutisches Präparat
US5484612A (en) * 1993-09-22 1996-01-16 The Board Of Trustees Of The Leland Stanford Junior University Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin
WO1996037192A1 (en) * 1995-05-26 1996-11-28 Vesifact Ag Pharmaceutical and cosmetic compositions containing sphingo- and glycolipids
US5637085A (en) * 1995-11-20 1997-06-10 Cardinale; Robert M. Method of cancer tumor treatment by slow release delivery of 1,2,4-benzotriazine oxides to tumor site

Also Published As

Publication number Publication date
DE69624935T2 (de) 2003-03-27
NO981042L (no) 1998-03-10
EP0868174A4 (hu) 1998-10-07
CZ289733B6 (cs) 2002-03-13
NO320019B1 (no) 2005-10-10
PT868174E (pt) 2003-04-30
CN1200669A (zh) 1998-12-02
HK1016889A1 (en) 1999-11-12
KR100475388B1 (ko) 2005-08-05
JPH11513365A (ja) 1999-11-16
US5597582A (en) 1997-01-28
CN1080113C (zh) 2002-03-06
HUP9802605A3 (en) 2000-02-28
CA2231545A1 (en) 1997-03-20
CA2231545C (en) 2008-07-15
DK0868174T3 (da) 2003-03-17
AU6780096A (en) 1997-04-01
KR19990044573A (ko) 1999-06-25
EP0868174B1 (en) 2002-11-20
ATE227982T1 (de) 2002-12-15
ES2187668T3 (es) 2003-06-16
EP0868174A1 (en) 1998-10-07
DE69624935D1 (de) 2003-01-02
NZ315964A (en) 1999-03-29
NO981042D0 (no) 1998-03-10
MX9801930A (es) 1998-10-31
AU702550B2 (en) 1999-02-25
WO1997009968A1 (en) 1997-03-20
CZ64498A3 (cs) 1998-08-12

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: SANOFI-AVENTIS U.S. LLC, US

Free format text: FORMER OWNER(S): SANOFI PHARMACEUTICALS, INC., US; SANOFI-SYNTHELABO INC., US

FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished