HUP0100634A2 - Pentaeritrit-tetranitrátot tartalmazó gyógyászati készítmények - Google Patents

Pentaeritrit-tetranitrátot tartalmazó gyógyászati készítmények

Info

Publication number
HUP0100634A2
HUP0100634A2 HU0100634A HUP0100634A HUP0100634A2 HU P0100634 A2 HUP0100634 A2 HU P0100634A2 HU 0100634 A HU0100634 A HU 0100634A HU P0100634 A HUP0100634 A HU P0100634A HU P0100634 A2 HUP0100634 A2 HU P0100634A2
Authority
HU
Hungary
Prior art keywords
pentaerythritol
tetranitrate
pentaerytritol
pharmaceutical preparations
products
Prior art date
Application number
HU0100634A
Other languages
English (en)
Inventor
Sabine Freitag
Ulrich Günther
Ulrike Kuntze
Wilhelm Thomas Lehr
Original Assignee
Isis Pharma Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Pharma Gmbh. filed Critical Isis Pharma Gmbh.
Publication of HUP0100634A2 publication Critical patent/HUP0100634A2/hu
Publication of HUP0100634A3 publication Critical patent/HUP0100634A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány új, különösen perorálisan beadható gyógyászatikészítményekre vonatkozik, amelyek hatóanyagként pentaeritrit-tetranitrátot (PETN) vagy anyagcseretermékeit olyan mennyiségbentartalmaznak, hogy naponta egyszeri beadással a beteg kielégítőellátása biztosított. A gyógyászati készítményekre jellemző, hogy a)hatóanyagként pentaeritritil-tetra-, pentaeritritil-tri-,pentaeritritil-di- vagy pentaeritritil-mononitrátot tartalmaznak b) 80mg-nál több és legfeljebb 600 mg mennyiségben c) a szokásos galenikus segédanyagok mellett. Ó
HU0100634A 1997-10-16 1998-10-16 Pharmaceutical preparations comprising pentaerytritol tetranitrate HUP0100634A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19745618 1997-10-16
PCT/DE1998/003030 WO1999018930A2 (de) 1997-10-16 1998-10-16 Pharmazeutische zubereitungen

Publications (2)

Publication Number Publication Date
HUP0100634A2 true HUP0100634A2 (hu) 2001-07-30
HUP0100634A3 HUP0100634A3 (en) 2003-07-28

Family

ID=7845649

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0100634A HUP0100634A3 (en) 1997-10-16 1998-10-16 Pharmaceutical preparations comprising pentaerytritol tetranitrate

Country Status (12)

Country Link
EP (1) EP1023059B1 (hu)
AT (1) ATE313323T1 (hu)
AU (1) AU1660399A (hu)
CZ (1) CZ301265B6 (hu)
DE (3) DE29880094U1 (hu)
DK (1) DK1023059T3 (hu)
ES (1) ES2255193T3 (hu)
HU (1) HUP0100634A3 (hu)
PL (1) PL340386A1 (hu)
SK (1) SK284769B6 (hu)
WO (1) WO1999018930A2 (hu)
ZA (1) ZA989356B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999067430A2 (de) * 1998-06-24 1999-12-29 Alpharma-Isis Gmbh & Co. Kg Analytische substrate und antioxidative mittel
DE102008050597A1 (de) 2008-10-09 2010-04-15 Actavis Deutschland Gmbh & Co. Kg Pharmazeutische Zubereitungen zur Anwendung in einem Verfahren zur therapeutischen Behandlung von Hörsturz

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3028307A (en) * 1959-05-27 1962-04-03 Warner Lambert Pharmaceutical Pre-dried granulation and production of sublingual compressed organic nitrate tablets with selected solubilizing agents
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
DE3381104D1 (de) * 1982-09-29 1990-02-22 Ici America Inc Organische nitrate enthaltende arzneimischungen, die gegen detonation durch feuer stabil sind.
DE3328094A1 (de) * 1983-08-04 1985-02-21 H. Trommsdorff GmbH & Co, 5110 Alsdorf Phlegmatisierte pharmazeutische zubereitung von explosionsfaehigen salpetersaeureestern
ATE89164T1 (de) * 1989-02-20 1993-05-15 Soorianarain Baligadoo Pharmazeutische herzschuetzende zusammensetzungen enthaltend amiodaron, ein nitroderivat, naemlich isosorbiddinitrat, und gegebenenfalls einen betablocker.
US5278192A (en) * 1992-07-02 1994-01-11 The Research Foundation Of State University Of New York Method of vasodilator therapy for treating a patient with a condition
DE4410997A1 (de) * 1994-03-30 1995-10-26 Isis Pharma Gmbh Pharmazeutische Zubereitungen und Arzneistoffe zur Prävention und Behandlung endothelialer Dysfunktionen

Also Published As

Publication number Publication date
ES2255193T3 (es) 2006-06-16
DK1023059T3 (da) 2006-04-24
ZA989356B (en) 1998-11-16
EP1023059A2 (de) 2000-08-02
CZ20001342A3 (cs) 2000-09-13
SK5382000A3 (en) 2000-11-07
SK284769B6 (sk) 2005-11-03
PL340386A1 (en) 2001-01-29
ATE313323T1 (de) 2006-01-15
WO1999018930A3 (de) 1999-10-07
DE19847781A1 (de) 1999-04-22
HUP0100634A3 (en) 2003-07-28
CZ301265B6 (cs) 2009-12-23
DE29880094U1 (de) 2000-05-18
DE59813300D1 (de) 2006-01-26
AU1660399A (en) 1999-05-03
WO1999018930A2 (de) 1999-04-22
EP1023059B1 (de) 2005-12-21

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees