HUP9800697A2 - D-vitamin-származékok dermatológiai felhasználása, új D-vitamin-származékok, eljárás előállításukra, intermedierek - Google Patents

D-vitamin-származékok dermatológiai felhasználása, új D-vitamin-származékok, eljárás előállításukra, intermedierek

Info

Publication number
HUP9800697A2
HUP9800697A2 HU9800697A HUP9800697A HUP9800697A2 HU P9800697 A2 HUP9800697 A2 HU P9800697A2 HU 9800697 A HU9800697 A HU 9800697A HU P9800697 A HUP9800697 A HU P9800697A HU P9800697 A2 HUP9800697 A2 HU P9800697A2
Authority
HU
Hungary
Prior art keywords
derivatives
vitamin
intermediates
producing
lower alkyl
Prior art date
Application number
HU9800697A
Other languages
English (en)
Inventor
Pierre Barbier
Marc Muller
Josef Stadlwieser
Original Assignee
F.Hoffmann-La Roche Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F.Hoffmann-La Roche Ag. filed Critical F.Hoffmann-La Roche Ag.
Publication of HUP9800697A2 publication Critical patent/HUP9800697A2/hu
Publication of HUP9800697A3 publication Critical patent/HUP9800697A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Az (I) általánős képletű D-vitamin-származékők (mely képletbenXjelentése =CH2 vagy H, H;Yjelentése -CH (CH3) -(A)n-C(O)-OR1 -CH(CH3)-CH2-O-C (O) -R2 vagy -C(O)-OR1 általánős képletű csőpőrt;Ajelentése -CH=CH- vagy -CH2- CH2-;R1jelentése kis szénatőmszámú alkil-, ciklőalkil-, ciklőalkil-metil-, -CH2R3 vagy -CH2-CH2R3;R2jelentése kis szénatőmszámú alkil-, ciklőalkil- vagy R3;R3jelentése hidrőxi-(kis szénatőmszámú alkil)-, hidrőxi-ciklőalkil- vagytriflűőrmetil-hidrőxi-(kis szénatőmszámú alkil)-csőpőrt;nértéke 0 vagy 1;és az 5-tagú gyűrűben levő pőntőzőtt vőnal adőtt esetben jelenlevőkötést jelent)dermatőlógiai állapőtők - különösen keratinizációs rendellenességek -kezelésére alkalmazhatók.ŕ
HU9800697A 1995-01-26 1996-01-17 Dermatological use of vitamin d derivatives, new vitamin d derivatives, process for producing them and intermediates HUP9800697A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95101030 1995-01-26

Publications (2)

Publication Number Publication Date
HUP9800697A2 true HUP9800697A2 (hu) 1998-07-28
HUP9800697A3 HUP9800697A3 (en) 1999-03-01

Family

ID=8218936

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9800697A HUP9800697A3 (en) 1995-01-26 1996-01-17 Dermatological use of vitamin d derivatives, new vitamin d derivatives, process for producing them and intermediates

Country Status (25)

Country Link
US (1) US5827883A (hu)
EP (1) EP0805682B1 (hu)
JP (1) JP2908566B2 (hu)
KR (1) KR19980701671A (hu)
CN (1) CN1168103A (hu)
AR (1) AR003107A1 (hu)
AT (1) ATE273010T1 (hu)
AU (1) AU4536796A (hu)
BR (1) BR9606856A (hu)
CA (1) CA2210884A1 (hu)
CO (1) CO4700475A1 (hu)
CZ (1) CZ238497A3 (hu)
DE (1) DE69633106T2 (hu)
EA (1) EA199700263A1 (hu)
ES (1) ES2225865T3 (hu)
FI (1) FI973124A (hu)
HU (1) HUP9800697A3 (hu)
IL (1) IL116825A0 (hu)
MA (1) MA23783A1 (hu)
NO (1) NO973455L (hu)
PE (1) PE28297A1 (hu)
PL (1) PL321638A1 (hu)
TR (1) TR199700694T1 (hu)
WO (1) WO1996022776A1 (hu)
ZA (1) ZA96452B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6184398B1 (en) * 1996-12-20 2001-02-06 Chugai Seiyaku Kabushiki Kaisha 16-ene-vitamin D derivatives
IL130484A (en) * 1996-12-20 2004-07-25 Chugai Pharmaceutical Co Ltd History of -16N-Vitamin-D
CA2664720C (en) * 2000-06-15 2011-11-22 Chugai Seiyaku Kabushiki Kaisha Vitamin d derivatives
US20040058895A1 (en) * 2002-09-18 2004-03-25 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
WO2005074389A2 (ja) * 2004-02-03 2005-08-18 Chugai Pharmaceutical Co Ltd ビタミンｄ化合物及びそれらの合成中間体の合成方法
KR20140097592A (ko) * 2004-12-03 2014-08-06 니뽄 신야쿠 가부시키가이샤 9,10-세코프레그난 유도체 및 의약
KR20140070627A (ko) 2006-06-02 2014-06-10 니뽄 신야쿠 가부시키가이샤 9,10-세코프레그난 유도체 및 의약
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
US20120184514A1 (en) * 2009-07-01 2012-07-19 Vitamin Derivatives Inc. Vitamin d compounds and methods for preparing same
PL237571B1 (pl) * 2017-05-23 2021-05-04 Inst Farmaceutyczny Kompozycja dermokosmetyczna do stosowania na skórę zawierająca syntetyczny prekursor analogu witaminy D
US20230065886A1 (en) * 2019-11-27 2023-03-02 Yonsung Fine Chemical Co., Ltd. Method for producing maxacalcitol, and intermediate therefor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2522962B2 (ja) * 1986-09-19 1996-08-07 中外製薬株式会社 乾癬治療剤
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
GB9004544D0 (en) * 1990-03-01 1990-04-25 Leo Pharm Prod Ltd Novel treatment ii
JP2903240B2 (ja) * 1990-03-23 1999-06-07 株式会社コーセー 皮膚外用剤

Also Published As

Publication number Publication date
EA199700263A1 (ru) 1998-02-26
HUP9800697A3 (en) 1999-03-01
ES2225865T3 (es) 2005-03-16
BR9606856A (pt) 1997-11-25
EP0805682B1 (en) 2004-08-11
DE69633106T2 (de) 2005-09-15
IL116825A0 (en) 1996-05-14
US5827883A (en) 1998-10-27
CA2210884A1 (en) 1996-08-01
JP2908566B2 (ja) 1999-06-21
CO4700475A1 (es) 1998-12-29
FI973124A0 (fi) 1997-07-25
DE69633106D1 (de) 2004-09-16
AU4536796A (en) 1996-08-14
CN1168103A (zh) 1997-12-17
ATE273010T1 (de) 2004-08-15
CZ238497A3 (en) 1997-11-12
PE28297A1 (es) 1997-08-20
FI973124A (fi) 1997-07-25
AR003107A1 (es) 1998-07-08
ZA96452B (en) 1996-07-26
KR19980701671A (ko) 1998-06-25
PL321638A1 (en) 1997-12-22
NO973455D0 (no) 1997-07-25
WO1996022776A1 (en) 1996-08-01
EP0805682A1 (en) 1997-11-12
MA23783A1 (fr) 1996-10-01
NO973455L (no) 1997-09-25
TR199700694T1 (xx) 1998-02-21
JPH10502940A (ja) 1998-03-17
MX9705648A (es) 1997-10-31

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