HUP0401546A2 - A 4-[4-[4-(hidroxi-difenil-metil)-1-piperidinil]-1-hidroxi-butil]-alfa,alfa-dimetil-benzol-ecetsavnak és hidrokloridjának új kristályformái és eljárás az előállításukra - Google Patents

A 4-[4-[4-(hidroxi-difenil-metil)-1-piperidinil]-1-hidroxi-butil]-alfa,alfa-dimetil-benzol-ecetsavnak és hidrokloridjának új kristályformái és eljárás az előállításukra

Info

Publication number
HUP0401546A2
HUP0401546A2 HU0401546A HUP0401546A HUP0401546A2 HU P0401546 A2 HUP0401546 A2 HU P0401546A2 HU 0401546 A HU0401546 A HU 0401546A HU P0401546 A HUP0401546 A HU P0401546A HU P0401546 A2 HUP0401546 A2 HU P0401546A2
Authority
HU
Hungary
Prior art keywords
alpha
hydrochloride
piperindinyl
hydroxydiphenylmethyl
hydroxybutyl
Prior art date
Application number
HU0401546A
Other languages
English (en)
Inventor
M. Satyanarayana Reddy
S. Thirumalai Rajan
U.V. Bhaskara Rao
Original Assignee
Dr. Reddy's Laboratories Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr. Reddy's Laboratories Ltd. filed Critical Dr. Reddy's Laboratories Ltd.
Publication of HUP0401546A2 publication Critical patent/HUP0401546A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A jelen találmány tárgyát az (1) képletű fexofenadin és fexofenadin-hidroklorid új polimorf kristályai és az azok előállítására szolgálóeljárások képezik. A jelen találmány azt célozza, hogy új tisztafexofenadin polimorfok és azok hidrokloridjai egyszerű,költséghatékony, kereskedelmileg használható, környezetbarát eljárásokútján legyenek előállíthatók. Ó
HU0401546A 2001-06-18 2001-07-31 A 4-[4-[4-(hidroxi-difenil-metil)-1-piperidinil]-1-hidroxi-butil]-alfa,alfa-dimetil-benzol-ecetsavnak és hidrokloridjának új kristályformái és eljárás az előállításukra HUP0401546A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN484MA2001 2001-06-18
PCT/US2001/023994 WO2002102777A2 (en) 2001-06-18 2001-07-31 NOVEL CRYSTALLINE FORMS OF 4-[4-[4-(HYDROXYDIPHENYLMETHYL)-1-PIPERINDINYL]-1-HYDROXYBUTYL]-α, α-DIMETHYLBENZENE ACETIC ACID AND ITS HYDROCHLORIDE

Publications (1)

Publication Number Publication Date
HUP0401546A2 true HUP0401546A2 (hu) 2004-12-28

Family

ID=34566868

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0401546A HUP0401546A2 (hu) 2001-06-18 2001-07-31 A 4-[4-[4-(hidroxi-difenil-metil)-1-piperidinil]-1-hidroxi-butil]-alfa,alfa-dimetil-benzol-ecetsavnak és hidrokloridjának új kristályformái és eljárás az előállításukra

Country Status (20)

Country Link
EP (2) EP2261209A1 (hu)
JP (2) JP2005507374A (hu)
KR (1) KR20040015734A (hu)
CN (1) CN100390145C (hu)
AU (1) AU2001278094B2 (hu)
BG (1) BG108435A (hu)
BR (1) BR0117054A (hu)
CA (2) CA2646802A1 (hu)
CO (1) CO5540340A2 (hu)
CZ (1) CZ20033358A3 (hu)
EE (1) EE200400010A (hu)
HU (1) HUP0401546A2 (hu)
IL (2) IL159266A0 (hu)
MX (1) MXPA03011728A (hu)
NZ (1) NZ530118A (hu)
PL (1) PL367632A1 (hu)
RU (1) RU2269516C2 (hu)
SK (1) SK15372003A3 (hu)
WO (1) WO2002102777A2 (hu)
ZA (1) ZA200309557B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2444456A1 (en) * 2001-04-09 2002-10-17 Teva Pharmaceutical Industries Ltd. Polymorphs of fexofenadine hydrochloride
WO2003104197A1 (en) * 2002-06-10 2003-12-18 Teva Pharmaceutical Industries Ltd. Polymorphic form xvi of fexofenadine hydrochloride
GB0319935D0 (en) * 2003-08-26 2003-09-24 Cipla Ltd Polymorphs
MXPA06012281A (es) * 2004-04-26 2007-07-18 Teva Pharma Formas cristalinas de clorhidrato de fexofenadina y procesos para su preparacion.
ITMI20041143A1 (it) * 2004-06-08 2004-09-08 Dipharma Spa Polimorfi di fexofenadina e procedimento per la loro preparazione
ITMI20041568A1 (it) * 2004-07-30 2004-10-30 Dipharma Spa "polimorfi di fexofenadina base"
EP1685106A2 (en) * 2004-09-28 2006-08-02 Teva Pharmaceutical Industries, Inc. Fexofendadine crystal form and processes for its preparation thereof
WO2007007347A1 (en) * 2005-07-07 2007-01-18 Wockhardt Limited Industrial process of fexofenadine hydrochloride with controlled side products
US20090306135A1 (en) 2008-03-24 2009-12-10 Mukesh Kumar Sharma Stable amorphous fexofenadine hydrochloride
CN104072402B (zh) * 2014-07-16 2016-08-17 昆山龙灯瑞迪制药有限公司 一种新结晶形式的盐酸非索非那定化合物及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254129A (en) 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
AU693892B2 (en) * 1994-05-18 1998-07-09 Aventisub Ii Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof
US6153754A (en) * 1995-12-21 2000-11-28 Albany Molecular Research, Inc. Process for production of piperidine derivatives
IN191492B (hu) 1999-05-25 2003-12-06 Ranbaxy Lab Ltd
GB0018691D0 (en) * 2000-07-28 2000-09-20 Rolabo Sl Process

Also Published As

Publication number Publication date
CN1518540A (zh) 2004-08-04
CA2646802A1 (en) 2002-12-27
CN100390145C (zh) 2008-05-28
JP2008094848A (ja) 2008-04-24
NZ530118A (en) 2007-05-31
KR20040015734A (ko) 2004-02-19
WO2002102777A3 (en) 2003-02-27
JP2005507374A (ja) 2005-03-17
PL367632A1 (en) 2005-03-07
BR0117054A (pt) 2004-07-27
CA2450858A1 (en) 2002-12-27
CA2450858C (en) 2009-04-07
AU2001278094B2 (en) 2006-01-12
RU2269516C2 (ru) 2006-02-10
WO2002102777A8 (en) 2003-10-30
EP2261209A1 (en) 2010-12-15
WO2002102777A2 (en) 2002-12-27
MXPA03011728A (es) 2004-07-08
EP1399422A2 (en) 2004-03-24
CZ20033358A3 (en) 2004-04-14
IL159266A0 (en) 2004-06-01
SK15372003A3 (sk) 2004-08-03
CO5540340A2 (es) 2005-07-29
EE200400010A (et) 2004-02-16
RU2004101045A (ru) 2005-06-27
BG108435A (en) 2004-12-30
IL159266A (en) 2010-11-30
ZA200309557B (en) 2004-09-14

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