BR0117054A - Formas cristalinas do ácido 4-[4-[4-hidroxidifenilmetil)-1-piperidinil]-1-hidroxibuti l]-alfa, alfa-dimetilbenzeno acético e seu cloridrato - Google Patents
Formas cristalinas do ácido 4-[4-[4-hidroxidifenilmetil)-1-piperidinil]-1-hidroxibuti l]-alfa, alfa-dimetilbenzeno acético e seu cloridratoInfo
- Publication number
- BR0117054A BR0117054A BR0117054-6A BR0117054A BR0117054A BR 0117054 A BR0117054 A BR 0117054A BR 0117054 A BR0117054 A BR 0117054A BR 0117054 A BR0117054 A BR 0117054A
- Authority
- BR
- Brazil
- Prior art keywords
- alpha
- hydrochloride
- hydroxydiphenylmethyl
- hydroxybutyl
- piperidinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
"FORMAS CRISTALINAS DO áCIDO 4-[4-[4-HIDROXIDIFENILMETIL)-1-PIPERIDINIL]-1-HIDROXIBUTI L]-ALFA,ALFA-DIMETIL-BENZENO ACéTICO E SEU CLORIDRATO". A presente invenção refere-se a novas formas polimorfas de Fexofenadina e de cloridrato de Fexofenadina de fórmula 1 e a processo de preparação das mesmas. A presente invenção também é direcionada para proporcionar novas formas polimorfas puras de Fexofenadina e de seu cloridrato por um processo simples que é custo efetivo, comercialmente viável e ambientalmente conveniente.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN484MA2001 | 2001-06-18 | ||
| PCT/US2001/023994 WO2002102777A2 (en) | 2001-06-18 | 2001-07-31 | NOVEL CRYSTALLINE FORMS OF 4-[4-[4-(HYDROXYDIPHENYLMETHYL)-1-PIPERINDINYL]-1-HYDROXYBUTYL]-α, α-DIMETHYLBENZENE ACETIC ACID AND ITS HYDROCHLORIDE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0117054A true BR0117054A (pt) | 2004-07-27 |
Family
ID=34566868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0117054-6A BR0117054A (pt) | 2001-06-18 | 2001-07-31 | Formas cristalinas do ácido 4-[4-[4-hidroxidifenilmetil)-1-piperidinil]-1-hidroxibuti l]-alfa, alfa-dimetilbenzeno acético e seu cloridrato |
Country Status (20)
| Country | Link |
|---|---|
| EP (2) | EP2261209A1 (pt) |
| JP (2) | JP2005507374A (pt) |
| KR (1) | KR20040015734A (pt) |
| CN (1) | CN100390145C (pt) |
| AU (1) | AU2001278094B2 (pt) |
| BG (1) | BG108435A (pt) |
| BR (1) | BR0117054A (pt) |
| CA (2) | CA2450858C (pt) |
| CO (1) | CO5540340A2 (pt) |
| CZ (1) | CZ20033358A3 (pt) |
| EE (1) | EE200400010A (pt) |
| HU (1) | HUP0401546A2 (pt) |
| IL (2) | IL159266A0 (pt) |
| MX (1) | MXPA03011728A (pt) |
| NZ (1) | NZ530118A (pt) |
| PL (1) | PL367632A1 (pt) |
| RU (1) | RU2269516C2 (pt) |
| SK (1) | SK15372003A3 (pt) |
| WO (1) | WO2002102777A2 (pt) |
| ZA (1) | ZA200309557B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL366576A1 (en) * | 2001-04-09 | 2005-02-07 | Teva Pharmaceutical Industries Ltd. | Polymorphs of fexofenadine hydrochloride |
| ES2239554T1 (es) | 2002-06-10 | 2005-10-01 | Teva Pharmaceutical Industries Ltd. | Forma xvi polimorfica de hidrocloruro de fexofenadina. |
| GB0319935D0 (en) | 2003-08-26 | 2003-09-24 | Cipla Ltd | Polymorphs |
| CA2560882A1 (en) * | 2004-04-26 | 2005-11-03 | Teva Pharmaceutical Industries Ltd. | Crystalline forms of fexofenadine hydrochloride and processes for their preparation |
| ITMI20041143A1 (it) * | 2004-06-08 | 2004-09-08 | Dipharma Spa | Polimorfi di fexofenadina e procedimento per la loro preparazione |
| ITMI20041568A1 (it) * | 2004-07-30 | 2004-10-30 | Dipharma Spa | "polimorfi di fexofenadina base" |
| WO2006037042A1 (en) * | 2004-09-28 | 2006-04-06 | Teva Pharmaceutical Industries Ltd. | Fexofenadine crystal form and processes for its preparation thereof |
| WO2007007347A1 (en) * | 2005-07-07 | 2007-01-18 | Wockhardt Limited | Industrial process of fexofenadine hydrochloride with controlled side products |
| US20090306135A1 (en) | 2008-03-24 | 2009-12-10 | Mukesh Kumar Sharma | Stable amorphous fexofenadine hydrochloride |
| CN104072402B (zh) * | 2014-07-16 | 2016-08-17 | 昆山龙灯瑞迪制药有限公司 | 一种新结晶形式的盐酸非索非那定化合物及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4254129A (en) | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
| CN1148849A (zh) * | 1994-05-18 | 1997-04-30 | 赫彻斯特马里恩鲁斯公司 | 抗组胺哌啶衍生物，其多晶形物和假同晶物的无水和水合物形式的制备方法 |
| US6153754A (en) * | 1995-12-21 | 2000-11-28 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
| IN191492B (pt) | 1999-05-25 | 2003-12-06 | Ranbaxy Lab Ltd | |
| GB0018691D0 (en) * | 2000-07-28 | 2000-09-20 | Rolabo Sl | Process |
-
2001
- 2001-07-31 EP EP10010066A patent/EP2261209A1/en not_active Withdrawn
- 2001-07-31 WO PCT/US2001/023994 patent/WO2002102777A2/en active IP Right Grant
- 2001-07-31 CA CA002450858A patent/CA2450858C/en not_active Expired - Fee Related
- 2001-07-31 CN CNB018233791A patent/CN100390145C/zh not_active Expired - Fee Related
- 2001-07-31 PL PL01367632A patent/PL367632A1/xx not_active Application Discontinuation
- 2001-07-31 KR KR10-2003-7016163A patent/KR20040015734A/ko not_active Application Discontinuation
- 2001-07-31 RU RU2004101045/04A patent/RU2269516C2/ru not_active IP Right Cessation
- 2001-07-31 CA CA002646802A patent/CA2646802A1/en not_active Abandoned
- 2001-07-31 BR BR0117054-6A patent/BR0117054A/pt not_active Application Discontinuation
- 2001-07-31 MX MXPA03011728A patent/MXPA03011728A/es active IP Right Grant
- 2001-07-31 EP EP01956057A patent/EP1399422A2/en not_active Withdrawn
- 2001-07-31 CZ CZ20033358A patent/CZ20033358A3/cs unknown
- 2001-07-31 AU AU2001278094A patent/AU2001278094B2/en not_active Ceased
- 2001-07-31 IL IL15926601A patent/IL159266A0/xx unknown
- 2001-07-31 SK SK1537-2003A patent/SK15372003A3/sk unknown
- 2001-07-31 JP JP2003505320A patent/JP2005507374A/ja active Pending
- 2001-07-31 EE EEP200400010A patent/EE200400010A/xx unknown
- 2001-07-31 HU HU0401546A patent/HUP0401546A2/hu unknown
- 2001-07-31 NZ NZ530118A patent/NZ530118A/en unknown
-
2003
- 2003-12-09 ZA ZA200309557A patent/ZA200309557B/xx unknown
- 2003-12-09 IL IL159266A patent/IL159266A/en not_active IP Right Cessation
- 2003-12-11 BG BG108435A patent/BG108435A/xx unknown
- 2003-12-18 CO CO03110519A patent/CO5540340A2/es not_active Application Discontinuation
-
2007
- 2007-11-06 JP JP2007289084A patent/JP2008094848A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008094848A (ja) | 2008-04-24 |
| HUP0401546A2 (hu) | 2004-12-28 |
| WO2002102777A3 (en) | 2003-02-27 |
| WO2002102777A2 (en) | 2002-12-27 |
| KR20040015734A (ko) | 2004-02-19 |
| RU2004101045A (ru) | 2005-06-27 |
| WO2002102777A8 (en) | 2003-10-30 |
| PL367632A1 (en) | 2005-03-07 |
| CA2450858A1 (en) | 2002-12-27 |
| CN100390145C (zh) | 2008-05-28 |
| RU2269516C2 (ru) | 2006-02-10 |
| CA2450858C (en) | 2009-04-07 |
| EE200400010A (et) | 2004-02-16 |
| NZ530118A (en) | 2007-05-31 |
| ZA200309557B (en) | 2004-09-14 |
| AU2001278094B2 (en) | 2006-01-12 |
| CA2646802A1 (en) | 2002-12-27 |
| EP2261209A1 (en) | 2010-12-15 |
| SK15372003A3 (sk) | 2004-08-03 |
| IL159266A (en) | 2010-11-30 |
| EP1399422A2 (en) | 2004-03-24 |
| IL159266A0 (en) | 2004-06-01 |
| CO5540340A2 (es) | 2005-07-29 |
| MXPA03011728A (es) | 2004-07-08 |
| CN1518540A (zh) | 2004-08-04 |
| JP2005507374A (ja) | 2005-03-17 |
| BG108435A (en) | 2004-12-30 |
| CZ20033358A3 (en) | 2004-04-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |