ATE455088T1 - Asymmetrische reduktive aminierung von ketosäurederivaten zur herstellung von aminosäurederivaten - Google Patents
Asymmetrische reduktive aminierung von ketosäurederivaten zur herstellung von aminosäurederivatenInfo
- Publication number
- ATE455088T1 ATE455088T1 AT04773427T AT04773427T ATE455088T1 AT E455088 T1 ATE455088 T1 AT E455088T1 AT 04773427 T AT04773427 T AT 04773427T AT 04773427 T AT04773427 T AT 04773427T AT E455088 T1 ATE455088 T1 AT E455088T1
- Authority
- AT
- Austria
- Prior art keywords
- acid derivatives
- amino acid
- reductive amination
- acid
- produce amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
- C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
- C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003326939 | 2003-09-18 | ||
PCT/JP2004/014048 WO2005028419A2 (en) | 2003-09-18 | 2004-09-17 | Asymmetric reductive amination of keto acid derivatives for producing amino acid derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE455088T1 true ATE455088T1 (de) | 2010-01-15 |
Family
ID=34372851
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04773427T ATE455088T1 (de) | 2003-09-18 | 2004-09-17 | Asymmetrische reduktive aminierung von ketosäurederivaten zur herstellung von aminosäurederivaten |
Country Status (7)
Country | Link |
---|---|
US (1) | US7626034B2 (de) |
EP (2) | EP1685092B1 (de) |
JP (1) | JP4705031B2 (de) |
AT (1) | ATE455088T1 (de) |
DE (1) | DE602004025132D1 (de) |
ES (1) | ES2337061T3 (de) |
WO (1) | WO2005028419A2 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1932824A4 (de) * | 2005-09-14 | 2011-11-02 | Japan Science & Tech Agency | Verfahren zur synthese einer ketosäure oder aminosäure durch hydratisierung einer acetylenverbindung |
UY30244A1 (es) | 2006-03-30 | 2007-11-30 | Tanabe Seiyaku Co | Un proceso para preparar derivados de tetrahidroquinolina |
US20090299089A1 (en) * | 2006-07-06 | 2009-12-03 | Basf Se | Method for producing optically active 3-aminocarboxylic acid esters |
CN101633625B (zh) | 2008-07-23 | 2013-02-13 | 江苏恒瑞医药股份有限公司 | R-β-氨基苯丁酸衍生物的制备方法 |
CN105566138A (zh) * | 2014-10-11 | 2016-05-11 | 上海科胜药物研发有限公司 | 一种合成西他列汀中间体的方法 |
CN105254519B (zh) * | 2015-11-25 | 2017-05-17 | 常州吉恩药业有限公司 | 一种西他列汀关键中间体的合成方法 |
WO2020212399A1 (en) | 2019-04-15 | 2020-10-22 | Janssen Pharmaceutica Nv | Method for preparing an alkyl trans-3-aminobicyclo[2.2.2]octane-2-carboxylic acid ester compound |
US20230210112A1 (en) * | 2020-06-05 | 2023-07-06 | Taminco Bv | Method for growing plants |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1265971A (de) | 1968-05-21 | 1972-03-08 | ||
US3664356A (en) * | 1970-07-30 | 1972-05-23 | M & J Valve Co | Pumping station sphere handling method and system |
US4386090A (en) * | 1980-12-22 | 1983-05-31 | Delalande S.A. | Nitrogen containing 2,3-dihydro naphthalenes, compositions and use |
EP0136883B1 (de) | 1983-10-03 | 1987-11-25 | E.R. Squibb & Sons, Inc. | Enkephalinase Inhibitoren |
IE58243B1 (en) * | 1983-12-07 | 1993-08-11 | Lonza Ag | A process for the preparation of optically-active 3-amino carboxylic acids |
US4521624A (en) * | 1984-04-16 | 1985-06-04 | Ethyl Corporation | Process for making cyclic amines |
JPH0678277B2 (ja) * | 1988-02-19 | 1994-10-05 | 高砂香料工業株式会社 | 光学活性アルコールおよびその誘導体の製造方法 |
JP2002540101A (ja) | 1999-03-22 | 2002-11-26 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | プロピオン酸3−アミノ−3−アリールの合成 |
DE19933611A1 (de) | 1999-07-17 | 2001-01-18 | Aventis Res & Tech Gmbh & Co | Verfahren zur Herstellung von Aminen durch homogen katalysierte reduktive Aminierung von Carbonylverbindungen |
WO2001056973A1 (de) * | 2000-02-04 | 2001-08-09 | Lonza Ag | Verfahren zur herstellung von acetoacetylierten aromatischen aminen |
US6646130B2 (en) * | 2001-07-19 | 2003-11-11 | Merck & Co., Inc. | Process to chiral integrin antagonist beta-amino acid intermediate |
WO2004058982A2 (en) | 2002-11-06 | 2004-07-15 | Penn State Research Foundation | Asymmetric reductive amination of ketones |
AR043515A1 (es) * | 2003-03-19 | 2005-08-03 | Merck & Co Inc | Procedimiento para preparar derivados quirales beta aminoacidos mediante hidrogenacion asimetrica |
US7145030B2 (en) * | 2003-04-24 | 2006-12-05 | Ajinomoto Co., Inc. | Production method for optically active N-aryl-β-amino acid compounds |
-
2004
- 2004-09-17 JP JP2006526814A patent/JP4705031B2/ja not_active Expired - Lifetime
- 2004-09-17 AT AT04773427T patent/ATE455088T1/de active
- 2004-09-17 EP EP04773427A patent/EP1685092B1/de not_active Expired - Lifetime
- 2004-09-17 US US10/571,855 patent/US7626034B2/en not_active Expired - Fee Related
- 2004-09-17 EP EP09163497.2A patent/EP2100875B1/de not_active Expired - Lifetime
- 2004-09-17 ES ES04773427T patent/ES2337061T3/es not_active Expired - Lifetime
- 2004-09-17 WO PCT/JP2004/014048 patent/WO2005028419A2/en active Application Filing
- 2004-09-17 DE DE602004025132T patent/DE602004025132D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US20070142443A1 (en) | 2007-06-21 |
WO2005028419A3 (en) | 2005-06-02 |
EP2100875A1 (de) | 2009-09-16 |
JP4705031B2 (ja) | 2011-06-22 |
JP2007505896A (ja) | 2007-03-15 |
DE602004025132D1 (de) | 2010-03-04 |
EP1685092B1 (de) | 2010-01-13 |
EP1685092A2 (de) | 2006-08-02 |
WO2005028419A2 (en) | 2005-03-31 |
EP2100875B1 (de) | 2016-11-16 |
ES2337061T3 (es) | 2010-04-20 |
US7626034B2 (en) | 2009-12-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE416163T1 (de) | Verfahren zur herstellung quartärer ammoniumverbindungen hoher reinheit | |
ATE346062T1 (de) | Verfahren zur herstellung von optisch-aktiven sulfoxid-derivaten | |
EA200900817A1 (ru) | Способ получения фторметилзамещённых гетероциклических соединений | |
EP1712549A4 (de) | Optisch aktives quaternäres ammoniumsalz mit axialer asymmetrie und verfahren zur herstellung von alpha-aminosäuren und derivaten davon unter dessen anwendung | |
ATE475634T1 (de) | Verfahren zur herstellung von isopulegol | |
ATE366725T1 (de) | Verfahren zur herstellung von gereinigten 1,3- substituierten imidazoliumsalzen | |
ATE440816T1 (de) | Neues verfahren zur synthese substituierter alpha-aminoindanderivate | |
ATE441627T1 (de) | Verfahren zur herstellung von valsartan | |
ATE413377T1 (de) | Verfahren zur kontinuierlichen quaternisierung tertiärer amine mit einem alkylhalogenid | |
ATE455088T1 (de) | Asymmetrische reduktive aminierung von ketosäurederivaten zur herstellung von aminosäurederivaten | |
ATE477227T1 (de) | Verfahren zur herstellung eines trans-4-amino-1- cyclohexancarbonsäurederivats | |
ATE555095T1 (de) | Verfahren zur herstellung von 3-hydroxy-n-alkyl-1-cycloalkyl-6-alkyl-4-oxo-1, -dihydropyridin-2- carbonsäureamid und damit verwandten analoga | |
KR20210066768A (ko) | 광학 활성 다이아민 유도체 및 티아졸 유도체의 생산을 위한 새로운 합성경로 | |
NO20053176L (no) | Fremgangsmate for fremstilling av tolperisonsalter. | |
CN103073484B (zh) | 一种甲哌卡因及其光学对映体的制备方法 | |
ATE496907T1 (de) | Verfahren zur herstellung von cilostazol | |
WO2004013082A3 (de) | Verfahren zur herstellung von aminoalkoxybenzylaminen und aminoalkoxybenzonitrilen als zwischenprodukte | |
ATE157971T1 (de) | Verfahren zur herstellung von aminotriazin- derivaten | |
ATE298743T1 (de) | Verfahren zur herstellung von lactamen | |
ATE414070T1 (de) | Verfahren zur herstellung von optisch aktiven 2,4-dihydrobenzofuranverbindungen | |
EP1340743A4 (de) | Optisch aktives aminderivat und syntheseverfahren | |
DE60031299D1 (de) | Verfahren zur herstellung von (aminomethyl)trifluoromethylcarbinol-derivaten | |
ATE346845T1 (de) | Ein verfahren zur herstellung substituierter alkylamin-derivate | |
DE602004020050D1 (de) | Verfahren zur herstellung substituierter imidazolderivate und in dem verfahren verwendete zwischenprodukte | |
EP1321452A3 (de) | Verfahren zur Herstellung optisch aktiver Amine oder deren Salze |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1685092 Country of ref document: EP |