HUP0302688A2 - Eljárások cilostazol előállítására - Google Patents
Eljárások cilostazol előállításáraInfo
- Publication number
- HUP0302688A2 HUP0302688A2 HU0302688A HUP0302688A HUP0302688A2 HU P0302688 A2 HUP0302688 A2 HU P0302688A2 HU 0302688 A HU0302688 A HU 0302688A HU P0302688 A HUP0302688 A HU P0302688A HU P0302688 A2 HUP0302688 A2 HU P0302688A2
- Authority
- HU
- Hungary
- Prior art keywords
- processes
- cilostazol
- preparing cilostazol
- preparing
- acilostazol
- Prior art date
Links
- RRGUKTPIGVIEKM-UHFFFAOYSA-N cilostazol Chemical compound C=1C=C2NC(=O)CCC2=CC=1OCCCCC1=NN=NN1C1CCCCC1 RRGUKTPIGVIEKM-UHFFFAOYSA-N 0.000 title abstract 3
- 229960004588 cilostazol Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 206010022562 Intermittent claudication Diseases 0.000 abstract 1
- 208000021156 intermittent vascular claudication Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22536200P | 2000-08-14 | 2000-08-14 | |
| PCT/US2001/025398 WO2002014283A1 (en) | 2000-08-14 | 2001-08-14 | Processes for preparing cilostazol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP0302688A2 true HUP0302688A2 (hu) | 2003-12-29 |
Family
ID=22844569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0302688A HUP0302688A2 (hu) | 2000-08-14 | 2001-08-14 | Eljárások cilostazol előállítására |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1311485A4 (no) |
| JP (2) | JP3845059B2 (no) |
| KR (1) | KR20030024865A (no) |
| CN (1) | CN1469864A (no) |
| AU (1) | AU2001284887A1 (no) |
| CA (1) | CA2419181A1 (no) |
| CZ (1) | CZ2003667A3 (no) |
| HK (1) | HK1053116A1 (no) |
| HU (1) | HUP0302688A2 (no) |
| IL (1) | IL154458A0 (no) |
| IS (1) | IS6716A (no) |
| MX (1) | MXPA03001470A (no) |
| NO (1) | NO20030699L (no) |
| NZ (1) | NZ524363A (no) |
| PL (1) | PL365672A1 (no) |
| SK (1) | SK2992003A3 (no) |
| WO (1) | WO2002014283A1 (no) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030045547A1 (en) | 2001-05-02 | 2003-03-06 | Shinji Aki | Process for producing carbostyril derivatives |
| US20050101631A1 (en) | 2002-08-01 | 2005-05-12 | Otsuka Pharmaceuticals Company | Process for producing carbostyril derivatives |
| US7399864B2 (en) | 2001-05-02 | 2008-07-15 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
| DK1489080T3 (da) | 2002-09-10 | 2011-04-04 | Otsuka Pharma Co Ltd | Fremgangsmåde til frembringelse af cilostazol |
| CA2559824A1 (en) * | 2004-02-05 | 2006-01-05 | Teva Pharmaceutical Industries Ltd. | Method of making 7-(4-bromobutoxy)-3,4-dihydrocarbostyril |
| KR100633232B1 (ko) * | 2004-08-25 | 2006-10-11 | 주식회사유한양행 | 신규한 6-[4-(1-시클로헥실-1ｈ-테트라졸-5-일)부톡시]-3,4-디히드로-2(1ｈ)-퀴놀리논 정제방법 |
| JP2008543953A (ja) * | 2006-04-20 | 2008-12-04 | テバ ファーマシューティカル インダストリーズ リミティド | エスゾピクロン結晶形態ａ、実質的に純粋なエスゾピクロン及び光学的に豊富なエスゾピクロンを調製するための方法 |
| TW200848041A (en) | 2007-03-30 | 2008-12-16 | Otsuka Pharma Co Ltd | A medicament for treating schizophrenia comprising cilostazol |
| ES2401914T3 (es) | 2007-04-25 | 2013-04-25 | Concert Pharmaceuticals Inc. | Análogos de Cilostazol |
| CN101434598B (zh) * | 2008-12-19 | 2012-11-07 | 重庆康乐制药有限公司 | 西洛他唑的制备方法 |
| CN102086190B (zh) * | 2011-01-28 | 2013-07-10 | 海南美兰史克制药有限公司 | 西洛他唑化合物及其制法 |
| CN107382970A (zh) * | 2017-07-26 | 2017-11-24 | 浙江金立源药业有限公司 | 一种西洛他唑的合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5535019A (en) * | 1978-09-01 | 1980-03-11 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| JPH01265051A (ja) * | 1988-04-14 | 1989-10-23 | Fuji Photo Film Co Ltd | ジアリールオキシアルカン製造方法 |
-
2001
- 2001-08-14 CN CNA018172083A patent/CN1469864A/zh active Pending
- 2001-08-14 AU AU2001284887A patent/AU2001284887A1/en not_active Abandoned
- 2001-08-14 CA CA002419181A patent/CA2419181A1/en not_active Abandoned
- 2001-08-14 SK SK299-2003A patent/SK2992003A3/sk unknown
- 2001-08-14 PL PL01365672A patent/PL365672A1/xx unknown
- 2001-08-14 WO PCT/US2001/025398 patent/WO2002014283A1/en not_active Application Discontinuation
- 2001-08-14 NZ NZ524363A patent/NZ524363A/en unknown
- 2001-08-14 MX MXPA03001470A patent/MXPA03001470A/es unknown
- 2001-08-14 HU HU0302688A patent/HUP0302688A2/hu unknown
- 2001-08-14 CZ CZ2003667A patent/CZ2003667A3/cs unknown
- 2001-08-14 KR KR10-2003-7002140A patent/KR20030024865A/ko not_active Application Discontinuation
- 2001-08-14 EP EP01963979A patent/EP1311485A4/en not_active Withdrawn
- 2001-08-14 JP JP2002519426A patent/JP3845059B2/ja not_active Expired - Fee Related
- 2001-08-14 IL IL15445801A patent/IL154458A0/xx unknown
-
2003
- 2003-02-13 NO NO20030699A patent/NO20030699L/no not_active Application Discontinuation
- 2003-02-13 IS IS6716A patent/IS6716A/is unknown
- 2003-07-25 HK HK03105399.3A patent/HK1053116A1/zh unknown
-
2005
- 2005-06-21 JP JP2005181031A patent/JP2005350474A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001284887A1 (en) | 2002-02-25 |
| WO2002014283A1 (en) | 2002-02-21 |
| NO20030699L (no) | 2003-04-10 |
| SK2992003A3 (en) | 2003-10-07 |
| EP1311485A4 (en) | 2004-05-12 |
| JP2005350474A (ja) | 2005-12-22 |
| IL154458A0 (en) | 2003-09-17 |
| NO20030699D0 (no) | 2003-02-13 |
| JP2004506043A (ja) | 2004-02-26 |
| JP3845059B2 (ja) | 2006-11-15 |
| CZ2003667A3 (cs) | 2003-08-13 |
| EP1311485A1 (en) | 2003-05-21 |
| MXPA03001470A (es) | 2005-06-30 |
| KR20030024865A (ko) | 2003-03-26 |
| CA2419181A1 (en) | 2002-02-21 |
| NZ524363A (en) | 2004-03-26 |
| CN1469864A (zh) | 2004-01-21 |
| HK1053116A1 (zh) | 2003-10-10 |
| PL365672A1 (en) | 2005-01-10 |
| IS6716A (is) | 2003-02-13 |
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