HUP0105345A2 - Megnövelt hatóanyag-stabilitású amlodipin-bezilát tabletta és eljárás az előállítására - Google Patents

Megnövelt hatóanyag-stabilitású amlodipin-bezilát tabletta és eljárás az előállítására

Info

Publication number
HUP0105345A2
HUP0105345A2 HU0105345A HUP0105345A HUP0105345A2 HU P0105345 A2 HUP0105345 A2 HU P0105345A2 HU 0105345 A HU0105345 A HU 0105345A HU P0105345 A HUP0105345 A HU P0105345A HU P0105345 A2 HUP0105345 A2 HU P0105345A2
Authority
HU
Hungary
Prior art keywords
weight
producing
same
extended stability
amlodipine
Prior art date
Application number
HU0105345A
Other languages
English (en)
Inventor
Pál Fekete
Ignácz Mária Királyné
Lászlóné Góra
Huszár Magdolna Leventiszné
Péter Tömpe
Magyar Olga Lonkainé
Pálné Szentgróti
Pálné Thuróczi
Original Assignee
EGIS Gyógyszergyár Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EGIS Gyógyszergyár Rt. filed Critical EGIS Gyógyszergyár Rt.
Priority to HU0105345A priority Critical patent/HU226642B1/hu
Publication of HUP0105345D0 publication Critical patent/HUP0105345D0/hu
Priority to SK286-2004A priority patent/SK2862004A3/sk
Priority to CZ2004791A priority patent/CZ2004791A3/cs
Priority to EP02788262A priority patent/EP1458384B1/en
Priority to YU54304A priority patent/RS54304A/sr
Priority to ES02788262T priority patent/ES2269787T3/es
Priority to UA20040705877A priority patent/UA74968C2/uk
Priority to DE60213464T priority patent/DE60213464T2/de
Priority to PL02370420A priority patent/PL370420A1/xx
Priority to PCT/HU2002/000145 priority patent/WO2003051364A1/en
Priority to EA200400801A priority patent/EA006826B1/ru
Priority to AT02788262T priority patent/ATE333877T1/de
Priority to AU2002353242A priority patent/AU2002353242A1/en
Priority to SI200230417T priority patent/SI1458384T1/sl
Publication of HUP0105345A2 publication Critical patent/HUP0105345A2/hu
Priority to HR20040582A priority patent/HRP20040582B1/xx
Priority to LT2004062A priority patent/LT5241B/lt
Priority to LVP-04-82A priority patent/LV13243B/en
Priority to BG108807A priority patent/BG108807A/xx
Publication of HUP0105345A3 publication Critical patent/HUP0105345A3/hu
Publication of HU226642B1 publication Critical patent/HU226642B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

A találmány tárgya megnövelt hatóanyag-stabilitású, csökkentett tömegűamlodipin-bezilát tabletta, mikrokristályos cellulóz, lubrikáns ésszétesést elősegítő anyagtartalommal, és eljárás az előállításra. Atalálmány szerinti tabletta hatóanyagként 4-6 tömeg% amlodipin-bezilátot, továbbá 87-94 tömeg% mikrokristályos cellulózt, 1-5 tömeg%szétesést elősegítő anyagot, 0,5-1,5 tömeg% lubrikánst és 0,2-1,0tömeg% kolloid szilícium-dioxidot tartalmaz. Ó
HU0105345A 2001-12-17 2001-12-17 Amlodipine bezylate tablets having extended stability and process for producing the same HU226642B1 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
HU0105345A HU226642B1 (en) 2001-12-17 2001-12-17 Amlodipine bezylate tablets having extended stability and process for producing the same
SI200230417T SI1458384T1 (sl) 2001-12-17 2002-12-17 Amlopidin bezilatne tablete z izboljsano stabilnostjo
PL02370420A PL370420A1 (en) 2001-12-17 2002-12-17 Amlopidine bezylate tablets with improved stability
EA200400801A EA006826B1 (ru) 2001-12-17 2002-12-17 Таблетки безилата амлодипина с улучшенной стабильностью
EP02788262A EP1458384B1 (en) 2001-12-17 2002-12-17 Amlopidine bezylate tablets with improved stability
YU54304A RS54304A (en) 2001-12-17 2002-12-17 Amlodipine bezylate tabletes with improved stability
ES02788262T ES2269787T3 (es) 2001-12-17 2002-12-17 Comprimidos de amlodipino besilato con estabilidad mejorada.
UA20040705877A UA74968C2 (en) 2001-12-17 2002-12-17 Amlodipine bezylate tablets with improved stability and process for their preparation
DE60213464T DE60213464T2 (de) 2001-12-17 2002-12-17 Amlopidinbezylat-tabletten mit verbesserter stabilität
SK286-2004A SK2862004A3 (en) 2001-12-17 2002-12-17 Amlodipine bezylate tablets with improved stability
PCT/HU2002/000145 WO2003051364A1 (en) 2001-12-17 2002-12-17 Amlopidine bezylate tablets with improved stability
CZ2004791A CZ2004791A3 (cs) 2001-12-17 2002-12-17 Tablety amlodipin besylátu se zlepšenou stabilitou
AT02788262T ATE333877T1 (de) 2001-12-17 2002-12-17 Amlopidinbezylat-tabletten mit verbesserter stabilität
AU2002353242A AU2002353242A1 (en) 2001-12-17 2002-12-17 Amlopidine bezylate tablets with improved stability
HR20040582A HRP20040582B1 (en) 2001-12-17 2004-06-23 Amlopidine bezylate tablets with improved stability
LT2004062A LT5241B (lt) 2001-12-17 2004-07-07 Amlodipino bezilato tabletės su pagerintu patvarumu
LVP-04-82A LV13243B (en) 2001-12-17 2004-07-16 Amlodipine bezylate tablets with improved stability
BG108807A BG108807A (en) 2001-12-17 2004-07-16 Amlodipine bezylate tablets with improved stability

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0105345A HU226642B1 (en) 2001-12-17 2001-12-17 Amlodipine bezylate tablets having extended stability and process for producing the same

Publications (4)

Publication Number Publication Date
HUP0105345D0 HUP0105345D0 (en) 2002-02-28
HUP0105345A2 true HUP0105345A2 (hu) 2003-12-29
HUP0105345A3 HUP0105345A3 (en) 2007-08-28
HU226642B1 HU226642B1 (en) 2009-05-28

Family

ID=90000366

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0105345A HU226642B1 (en) 2001-12-17 2001-12-17 Amlodipine bezylate tablets having extended stability and process for producing the same

Country Status (17)

Country Link
EP (1) EP1458384B1 (hu)
AT (1) ATE333877T1 (hu)
AU (1) AU2002353242A1 (hu)
BG (1) BG108807A (hu)
CZ (1) CZ2004791A3 (hu)
DE (1) DE60213464T2 (hu)
EA (1) EA006826B1 (hu)
ES (1) ES2269787T3 (hu)
HR (1) HRP20040582B1 (hu)
HU (1) HU226642B1 (hu)
LT (1) LT5241B (hu)
LV (1) LV13243B (hu)
PL (1) PL370420A1 (hu)
RS (1) RS54304A (hu)
SK (1) SK2862004A3 (hu)
UA (1) UA74968C2 (hu)
WO (1) WO2003051364A1 (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006059217A1 (en) * 2004-12-01 2006-06-08 Ranbaxy Laboratories Limited Stable solid dosage forms of amlodipine besylate and processes for their preparation
JO3239B1 (ar) 2008-09-22 2018-03-08 Novartis Ag تركيبات جالينية من مركبات عضوية
JP4954961B2 (ja) * 2008-10-06 2012-06-20 大日本住友製薬株式会社 光安定性の向上した組成物
JP5689052B2 (ja) * 2011-12-26 2015-03-25 大日本住友製薬株式会社 光安定性の向上した組成物
EP2814465B1 (en) 2012-02-17 2019-07-03 Egis Gyógyszergyár Zrt. Pharmaceutical formulation having improved stability
PL236001B1 (pl) 2012-12-21 2020-11-30 Adamed Spolka Z Ograniczona Odpowiedzialnoscia Złożona kompozycja farmaceutyczna zawierająca kandesartan cyleksetylu oraz amlodypinę, sposób jej wytwarzania oraz jednostkowa postać dawkowania zawierająca tę kompozycję
US10350171B2 (en) 2017-07-06 2019-07-16 Dexcel Ltd. Celecoxib and amlodipine formulation and method of making the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8608335D0 (en) * 1986-04-04 1986-05-08 Pfizer Ltd Pharmaceutically acceptable salts
DE19857716A1 (de) * 1998-12-15 2000-06-21 Bayer Ag Neue feste Formulierung von Metrifonat
WO2003032954A1 (en) * 2001-10-17 2003-04-24 Dr. Reddy's Laboratories Ltd. Stabilized pharmaceutical formulations containing amlodipine maleate

Also Published As

Publication number Publication date
BG108807A (en) 2005-03-31
ATE333877T1 (de) 2006-08-15
RS54304A (en) 2006-12-15
DE60213464D1 (de) 2006-09-07
UA74968C2 (en) 2006-02-15
EA006826B1 (ru) 2006-04-28
SK2862004A3 (en) 2004-11-03
AU2002353242A1 (en) 2003-06-30
HU226642B1 (en) 2009-05-28
HRP20040582B1 (en) 2007-08-31
EP1458384A1 (en) 2004-09-22
EA200400801A1 (ru) 2004-12-30
HRP20040582A2 (en) 2005-02-28
EP1458384B1 (en) 2006-07-26
LT2004062A (en) 2005-02-25
DE60213464T2 (de) 2007-03-01
WO2003051364A1 (en) 2003-06-26
LT5241B (lt) 2005-07-25
ES2269787T3 (es) 2007-04-01
PL370420A1 (en) 2005-05-30
HUP0105345D0 (en) 2002-02-28
HUP0105345A3 (en) 2007-08-28
CZ2004791A3 (cs) 2004-10-13
LV13243B (en) 2005-05-20

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Legal Events

Date Code Title Description
HC9A Change of name, address

Owner name: EGIS GYOGYSZERGYAR NYILVANOSAN MUEKOEDOE RESZV, HU

Free format text: FORMER OWNER(S): EGIS GYOGYSZERGYAR RT., HU