BG108807A - Amlodipine bezylate tablets with improved stability - Google Patents
Amlodipine bezylate tablets with improved stabilityInfo
- Publication number
- BG108807A BG108807A BG108807A BG10880704A BG108807A BG 108807 A BG108807 A BG 108807A BG 108807 A BG108807 A BG 108807A BG 10880704 A BG10880704 A BG 10880704A BG 108807 A BG108807 A BG 108807A
- Authority
- BG
- Bulgaria
- Prior art keywords
- weight
- tablets
- improved stability
- amlodipine
- benzylate
- Prior art date
Links
- HTIQEAQVCYTUBX-UHFFFAOYSA-N amlodipine Chemical compound CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1Cl HTIQEAQVCYTUBX-UHFFFAOYSA-N 0.000 title abstract 3
- 229960000528 amlodipine Drugs 0.000 title abstract 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000000314 lubricant Substances 0.000 abstract 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 2
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 2
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 229940075614 colloidal silicon dioxide Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0105345A HU226642B1 (en) | 2001-12-17 | 2001-12-17 | Amlodipine bezylate tablets having extended stability and process for producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG108807A true BG108807A (en) | 2005-03-31 |
Family
ID=90000366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG108807A BG108807A (en) | 2001-12-17 | 2004-07-16 | Amlodipine bezylate tablets with improved stability |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1458384B1 (hu) |
| AT (1) | ATE333877T1 (hu) |
| AU (1) | AU2002353242A1 (hu) |
| BG (1) | BG108807A (hu) |
| CZ (1) | CZ2004791A3 (hu) |
| DE (1) | DE60213464T2 (hu) |
| EA (1) | EA006826B1 (hu) |
| ES (1) | ES2269787T3 (hu) |
| HR (1) | HRP20040582B1 (hu) |
| HU (1) | HU226642B1 (hu) |
| LT (1) | LT5241B (hu) |
| LV (1) | LV13243B (hu) |
| PL (1) | PL370420A1 (hu) |
| RS (1) | RS54304A (hu) |
| SK (1) | SK2862004A3 (hu) |
| UA (1) | UA74968C2 (hu) |
| WO (1) | WO2003051364A1 (hu) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006059217A1 (en) * | 2004-12-01 | 2006-06-08 | Ranbaxy Laboratories Limited | Stable solid dosage forms of amlodipine besylate and processes for their preparation |
| JO3239B1 (ar) | 2008-09-22 | 2018-03-08 | Novartis Ag | تركيبات جالينية من مركبات عضوية |
| JP4954961B2 (ja) * | 2008-10-06 | 2012-06-20 | 大日本住友製薬株式会社 | 光安定性の向上した組成物 |
| JP5689052B2 (ja) * | 2011-12-26 | 2015-03-25 | 大日本住友製薬株式会社 | 光安定性の向上した組成物 |
| WO2013121233A1 (en) | 2012-02-17 | 2013-08-22 | Egis Gyógyszergyár Nyilvánosan Működö Részvénytársaság | Pharmaceutical formulation having improved stability |
| PL236001B1 (pl) | 2012-12-21 | 2020-11-30 | Adamed Spolka Z Ograniczona Odpowiedzialnoscia | Złożona kompozycja farmaceutyczna zawierająca kandesartan cyleksetylu oraz amlodypinę, sposób jej wytwarzania oraz jednostkowa postać dawkowania zawierająca tę kompozycję |
| US10350171B2 (en) | 2017-07-06 | 2019-07-16 | Dexcel Ltd. | Celecoxib and amlodipine formulation and method of making the same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8608335D0 (en) * | 1986-04-04 | 1986-05-08 | Pfizer Ltd | Pharmaceutically acceptable salts |
| DE19857716A1 (de) * | 1998-12-15 | 2000-06-21 | Bayer Ag | Neue feste Formulierung von Metrifonat |
| WO2003032954A1 (en) * | 2001-10-17 | 2003-04-24 | Dr. Reddy's Laboratories Ltd. | Stabilized pharmaceutical formulations containing amlodipine maleate |
-
2001
- 2001-12-17 HU HU0105345A patent/HU226642B1/hu unknown
-
2002
- 2002-12-17 EA EA200400801A patent/EA006826B1/ru not_active IP Right Cessation
- 2002-12-17 UA UA20040705877A patent/UA74968C2/uk unknown
- 2002-12-17 EP EP02788262A patent/EP1458384B1/en not_active Expired - Lifetime
- 2002-12-17 AT AT02788262T patent/ATE333877T1/de not_active IP Right Cessation
- 2002-12-17 DE DE60213464T patent/DE60213464T2/de not_active Expired - Fee Related
- 2002-12-17 WO PCT/HU2002/000145 patent/WO2003051364A1/en active IP Right Grant
- 2002-12-17 RS YU54304A patent/RS54304A/sr unknown
- 2002-12-17 AU AU2002353242A patent/AU2002353242A1/en not_active Abandoned
- 2002-12-17 ES ES02788262T patent/ES2269787T3/es not_active Expired - Lifetime
- 2002-12-17 SK SK286-2004A patent/SK2862004A3/sk unknown
- 2002-12-17 PL PL02370420A patent/PL370420A1/xx not_active IP Right Cessation
- 2002-12-17 CZ CZ2004791A patent/CZ2004791A3/cs unknown
-
2004
- 2004-06-23 HR HR20040582A patent/HRP20040582B1/xx not_active IP Right Cessation
- 2004-07-07 LT LT2004062A patent/LT5241B/lt not_active IP Right Cessation
- 2004-07-16 BG BG108807A patent/BG108807A/xx unknown
- 2004-07-16 LV LVP-04-82A patent/LV13243B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| UA74968C2 (en) | 2006-02-15 |
| AU2002353242A1 (en) | 2003-06-30 |
| HUP0105345A3 (en) | 2007-08-28 |
| DE60213464T2 (de) | 2007-03-01 |
| ES2269787T3 (es) | 2007-04-01 |
| LT2004062A (en) | 2005-02-25 |
| DE60213464D1 (de) | 2006-09-07 |
| HRP20040582A2 (en) | 2005-02-28 |
| EP1458384B1 (en) | 2006-07-26 |
| HUP0105345D0 (en) | 2002-02-28 |
| LV13243B (en) | 2005-05-20 |
| CZ2004791A3 (cs) | 2004-10-13 |
| PL370420A1 (en) | 2005-05-30 |
| LT5241B (lt) | 2005-07-25 |
| EA006826B1 (ru) | 2006-04-28 |
| HUP0105345A2 (hu) | 2003-12-29 |
| WO2003051364A1 (en) | 2003-06-26 |
| HRP20040582B1 (en) | 2007-08-31 |
| SK2862004A3 (en) | 2004-11-03 |
| RS54304A (en) | 2006-12-15 |
| ATE333877T1 (de) | 2006-08-15 |
| EP1458384A1 (en) | 2004-09-22 |
| EA200400801A1 (ru) | 2004-12-30 |
| HU226642B1 (en) | 2009-05-28 |
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