HUP0104394A3 - Particles coated with granulated crystalline ibuprofen - Google Patents

Particles coated with granulated crystalline ibuprofen

Info

Publication number
HUP0104394A3
HUP0104394A3 HU0104394A HUP0104394A HUP0104394A3 HU P0104394 A3 HUP0104394 A3 HU P0104394A3 HU 0104394 A HU0104394 A HU 0104394A HU P0104394 A HUP0104394 A HU P0104394A HU P0104394 A3 HUP0104394 A3 HU P0104394A3
Authority
HU
Hungary
Prior art keywords
particles coated
crystalline ibuprofen
granulated crystalline
granulated
ibuprofen
Prior art date
Application number
HU0104394A
Other languages
English (en)
Original Assignee
Ethypharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm Sa filed Critical Ethypharm Sa
Publication of HUP0104394A2 publication Critical patent/HUP0104394A2/hu
Publication of HUP0104394A3 publication Critical patent/HUP0104394A3/hu
Publication of HU229936B1 publication Critical patent/HU229936B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Glanulating (AREA)
HU0104394A 1998-11-06 1999-11-03 Particles coated with granulated crystalline ibuprofen HU229936B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9814033A FR2785539B1 (fr) 1998-11-06 1998-11-06 Particules enrobees d'ibuprofene cristallin granule
PCT/FR1999/002682 WO2000027368A1 (fr) 1998-11-06 1999-11-03 Particules enrobees d'ibuprofene cristallin granule

Publications (3)

Publication Number Publication Date
HUP0104394A2 HUP0104394A2 (hu) 2002-03-28
HUP0104394A3 true HUP0104394A3 (en) 2002-12-28
HU229936B1 HU229936B1 (en) 2015-01-28

Family

ID=9532492

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104394A HU229936B1 (en) 1998-11-06 1999-11-03 Particles coated with granulated crystalline ibuprofen

Country Status (26)

Country Link
US (1) US6951657B1 (hu)
EP (1) EP1126829B1 (hu)
JP (1) JP3987282B2 (hu)
KR (1) KR100586059B1 (hu)
CN (1) CN1154482C (hu)
AT (1) ATE265206T1 (hu)
AU (1) AU765765B2 (hu)
BR (1) BR9915111A (hu)
CA (1) CA2349503C (hu)
CZ (1) CZ292290B6 (hu)
DE (1) DE69916876T2 (hu)
DK (1) DK1126829T3 (hu)
EA (1) EA002897B1 (hu)
ES (1) ES2219073T3 (hu)
FR (1) FR2785539B1 (hu)
HK (1) HK1039890B (hu)
HU (1) HU229936B1 (hu)
IL (1) IL142787A (hu)
MX (1) MXPA01004517A (hu)
NZ (1) NZ511479A (hu)
PL (1) PL194527B1 (hu)
PT (1) PT1126829E (hu)
SK (1) SK283944B6 (hu)
TR (1) TR200101230T2 (hu)
WO (1) WO2000027368A1 (hu)
ZA (1) ZA200103630B (hu)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2795962B1 (fr) * 1999-07-08 2003-05-09 Prographarm Laboratoires Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif
FR2824477B1 (fr) * 2001-05-09 2005-09-09 Ethypharm Lab Prod Ethiques Granules enrobes a base d'inhibiteur de l'enzyme de conversion de l'anfiotensine, leur procede de preparation et comprimes orodispersibles contenant les granules enrobes
FR2850275B1 (fr) * 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
RU2403033C2 (ru) * 2005-03-22 2010-11-10 Лозан Фарма Гмбх Солюбилизированный ибупрофен
EP1800667A1 (en) 2005-12-23 2007-06-27 Losan Pharma GmbH Rapidly solubilizing ibuprofen granulate
US20080020040A1 (en) * 2006-07-18 2008-01-24 Horizon Therapeutics, Inc. Unit dose form for administration of ibuprofen
US8067451B2 (en) * 2006-07-18 2011-11-29 Horizon Pharma Usa, Inc. Methods and medicaments for administration of ibuprofen
NZ565846A (en) * 2005-07-18 2011-12-22 Horizon Therapeutics Inc Medicaments containing famotidine and ibuprofen and administration of same
DE102005049001A1 (de) * 2005-10-11 2007-04-12 Basf Ag Verfahren zur Herstellung von direkttablettierbaren Ibuprofen-Formulierungen
US8067033B2 (en) 2007-11-30 2011-11-29 Horizon Pharma Usa, Inc. Stable compositions of famotidine and ibuprofen
MX2009001085A (es) * 2006-07-27 2009-03-23 Univ Sunderland Composicion para recubrimiento que comprende almidon.
TWI564008B (zh) * 2010-09-30 2017-01-01 鹽野義製藥股份有限公司 難溶性藥物之溶解性改善製劑
WO2014198999A1 (en) * 2013-06-13 2014-12-18 Opes Corporation Oy Matrix
US9474699B2 (en) * 2014-03-31 2016-10-25 Johnson & Johnson Consumer Inc. Compostions and methods for enhancing the topical application of a basic benefit agent
EP3220913B1 (en) * 2014-11-19 2021-09-08 Kiromic BioPharma, Inc. Nanoparticle-based vaccine targeting cancer/testis antigens (cta) and its use in solid and hematological malignancies
WO2019080693A1 (zh) 2017-10-26 2019-05-02 浙江越甲药业有限公司 一种稳定的含有非甾体抗炎药衍生物的药物组合物
TW202045140A (zh) 2019-02-22 2020-12-16 英商康泰倫特英國斯文敦載迪斯有限公司 保存水性懸浮液中以無溶劑混合方法製備的功能性塗覆之活性醫藥成份微粒
MX2021009679A (es) 2019-02-22 2021-09-10 Catalent Uk Swindon Zydis Ltd Minimizacion de aglomeracion, aireacion y conservacion del revestimiento de composiciones farmaceuticas que comprenden ibuprofeno.
SG11202109022UA (en) 2019-02-22 2021-09-29 Catalent Uk Swindon Zydis Ltd Minimizing agglomeration of drug particle coating material during storage to stabilize disintegration times of pharmaceutical products

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4308251A (en) * 1980-01-11 1981-12-29 Boots Pharmaceuticals, Inc. Controlled release formulations of orally-active medicaments
US4588612A (en) * 1985-04-24 1986-05-13 Scm Corporation Pretreatment in encapsulation process
GB8519310D0 (en) * 1985-07-31 1985-09-04 Zyma Sa Granular active substances
US4835186A (en) 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US4835187A (en) * 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US5084278A (en) * 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
NZ234587A (en) * 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
IT1241417B (it) * 1990-03-06 1994-01-14 Vectorpharma Int Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione
ATE121619T1 (de) * 1990-04-11 1995-05-15 Upjohn Co Verfahren zum geschmacksabdecken von ibuprofen.
FR2679451B1 (fr) * 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
US5191114A (en) * 1991-10-09 1993-03-02 Sage Pharmaceuticals, Inc. Process for enhancing the flow characteristics of ibuprofen
ZA945944B (en) * 1993-08-13 1996-02-08 Eurand America Inc Procedure for encapsulating nsaids
US5567439A (en) * 1994-06-14 1996-10-22 Fuisz Technologies Ltd. Delivery of controlled-release systems(s)

Also Published As

Publication number Publication date
AU1050800A (en) 2000-05-29
IL142787A (en) 2007-06-03
KR100586059B1 (ko) 2006-06-07
EA002897B1 (ru) 2002-10-31
WO2000027368A1 (fr) 2000-05-18
JP2002529399A (ja) 2002-09-10
ES2219073T3 (es) 2004-11-16
PL347549A1 (en) 2002-04-08
HUP0104394A2 (hu) 2002-03-28
JP3987282B2 (ja) 2007-10-03
EP1126829B1 (fr) 2004-04-28
CA2349503A1 (fr) 2000-05-18
CZ292290B6 (cs) 2003-08-13
EA200100491A1 (ru) 2001-12-24
FR2785539A1 (fr) 2000-05-12
DK1126829T3 (da) 2004-08-09
NZ511479A (en) 2003-02-28
PT1126829E (pt) 2004-08-31
BR9915111A (pt) 2001-11-27
FR2785539B1 (fr) 2004-04-09
ATE265206T1 (de) 2004-05-15
AU765765B2 (en) 2003-09-25
DE69916876D1 (de) 2004-06-03
KR20010090830A (ko) 2001-10-19
CN1154482C (zh) 2004-06-23
HU229936B1 (en) 2015-01-28
EP1126829A1 (fr) 2001-08-29
SK5662001A3 (en) 2001-11-06
US6951657B1 (en) 2005-10-04
DE69916876T2 (de) 2005-03-31
ZA200103630B (en) 2002-05-06
MXPA01004517A (es) 2003-06-09
CA2349503C (fr) 2010-07-13
CZ20011434A3 (cs) 2001-09-12
TR200101230T2 (tr) 2001-10-22
HK1039890A1 (en) 2002-05-17
PL194527B1 (pl) 2007-06-29
CN1328450A (zh) 2001-12-26
HK1039890B (zh) 2005-01-07
SK283944B6 (sk) 2004-05-04

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