HUP0004809A2 - Többgyűrűs eritromicin-származékok - Google Patents

Többgyűrűs eritromicin-származékok

Info

Publication number
HUP0004809A2
HUP0004809A2 HU0004809A HUP0004809A HUP0004809A2 HU P0004809 A2 HUP0004809 A2 HU P0004809A2 HU 0004809 A HU0004809 A HU 0004809A HU P0004809 A HUP0004809 A HU P0004809A HU P0004809 A2 HUP0004809 A2 HU P0004809A2
Authority
HU
Hungary
Prior art keywords
erythromycin derivatives
compounds
antibacterial effect
derivatives
multicyclic
Prior art date
Application number
HU0004809A
Other languages
English (en)
Inventor
Daniel T. Chu
George W. Griesgraber
Yat Sun Or
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of HUP0004809A2 publication Critical patent/HUP0004809A2/hu
Publication of HUP0004809A3 publication Critical patent/HUP0004809A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

A találmány szemi-szintetikus makrolidokra, közelebbrőlkondenzált aromás és heterociklusos csoportokkal szubsztituáltantibakteriális hatású eritromicinszármazékokra, ilyen vegyületekettartalmazó gyógy- szerkészítményekre és a vegyületek előállításieljárására vonatkozik. A találmány szerinti többgyűrűseritromicinszármazékok fokozott antibakteriális hatásúak, arezisztencia kialakulása csökkent és nem várt módon szelektívekbizonyos mikroorganizmusokkal szemben. Ó
HU0004809A 1997-05-29 1998-05-22 Multicyclic erythromycin derivatives HUP0004809A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86545397A 1997-05-29 1997-05-29
PCT/US1998/010501 WO1998054197A1 (en) 1997-05-29 1998-05-22 Multicyclic erythromycin derivatives

Publications (2)

Publication Number Publication Date
HUP0004809A2 true HUP0004809A2 (hu) 2001-05-28
HUP0004809A3 HUP0004809A3 (en) 2001-11-28

Family

ID=25345545

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004809A HUP0004809A3 (en) 1997-05-29 1998-05-22 Multicyclic erythromycin derivatives

Country Status (26)

Country Link
EP (1) EP0984975B1 (hu)
JP (1) JP4368950B2 (hu)
KR (1) KR20010013041A (hu)
CN (1) CN1258299A (hu)
AR (1) AR013081A1 (hu)
AT (1) ATE238330T1 (hu)
AU (1) AU7591298A (hu)
BG (1) BG103985A (hu)
BR (1) BR9809489A (hu)
CA (1) CA2290421C (hu)
CO (1) CO4950620A1 (hu)
DE (1) DE69813798T2 (hu)
DK (1) DK0984975T3 (hu)
ES (1) ES2197472T3 (hu)
HU (1) HUP0004809A3 (hu)
IL (1) IL132482A0 (hu)
MX (1) MXPA99011001A (hu)
NO (1) NO995842L (hu)
NZ (1) NZ500531A (hu)
PL (1) PL337066A1 (hu)
PT (1) PT984975E (hu)
SI (1) SI0984975T1 (hu)
SK (1) SK160299A3 (hu)
TR (1) TR199902820T2 (hu)
WO (1) WO1998054197A1 (hu)
ZA (1) ZA984488B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE250076T1 (de) * 1999-06-07 2003-10-15 Abbott Lab 6-o-carbamat ketolide derivate
US20100035832A1 (en) * 2005-01-12 2010-02-11 Alpharma Aps Macrolides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE145212T1 (de) * 1992-04-22 1996-11-15 Taisho Pharmaceutical Co Ltd 5-0-desosaminylerythronolide a derivate
ES2218604T3 (es) * 1995-11-08 2004-11-16 Abbott Laboratories Derivados triciclicos de eritromicina.

Also Published As

Publication number Publication date
ES2197472T3 (es) 2004-01-01
JP4368950B2 (ja) 2009-11-18
DK0984975T3 (da) 2003-08-11
PL337066A1 (en) 2000-07-31
AR013081A1 (es) 2000-12-13
WO1998054197A1 (en) 1998-12-03
JP2002500669A (ja) 2002-01-08
EP0984975A1 (en) 2000-03-15
EP0984975B1 (en) 2003-04-23
NO995842L (no) 2000-01-26
CO4950620A1 (es) 2000-09-01
BG103985A (en) 2000-07-31
NZ500531A (en) 2001-07-27
DE69813798D1 (en) 2003-05-28
DE69813798T2 (de) 2004-02-19
SK160299A3 (en) 2000-06-12
HUP0004809A3 (en) 2001-11-28
ATE238330T1 (de) 2003-05-15
CN1258299A (zh) 2000-06-28
TR199902820T2 (xx) 2000-04-21
MXPA99011001A (es) 2003-09-10
PT984975E (pt) 2003-09-30
AU7591298A (en) 1998-12-30
CA2290421A1 (en) 1998-12-03
NO995842D0 (no) 1999-11-29
IL132482A0 (en) 2001-03-19
ZA984488B (en) 1998-12-02
SI0984975T1 (en) 2004-02-29
KR20010013041A (ko) 2001-02-26
CA2290421C (en) 2007-05-08
BR9809489A (pt) 2000-06-20

Similar Documents

Publication Publication Date Title
HK1043725A1 (en) Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof.
AU7484896A (en) Isolation and purification of paclitaxel from organic matter containing paclitaxel, cephalomannine and other related taxanes
ZA200007222B (en) Glycopeptide derivatives and pharmaceutical compositions containing the same.
AU3213993A (en) Tetrahydropyrimidine derivatives and pharmaceutical compositions containing them
HK1031869A1 (en) 1-Ä(1-Substituted-4-piperidinyl)methylÜ-4-piperdine derivatives, process for producing the same, medicinal compositions containing the same and intermediates of these compounds.
AU1231697A (en) Novel substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof
AU6594790A (en) Benzoxazine derivatives, pharmaceutical compositions containing them and processes for their production
PT717041E (pt) Hidratos de paclitaxel cristalinos
GB2380675A (en) Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives
PT876388E (pt) Derivados de eritromicina triciclica
AU6491686A (en) Silylated erythromycin derivative antibiotics
AU7306096A (en) Aryl-piperazine cyclic amine derivatives, preparation thereof and pharmaceutical compositions containing same
PT842185E (pt) Derivados da ara-c
AR009809A1 (es) Derivados de 10,13,15-trioxatriciclo[9.2.1(9.6)]-pentadecanona, procedimientos para su preparacion y medicamentos que contienen estos compuestos
HUP0004809A2 (hu) Többgyűrűs eritromicin-származékok
MD1788F2 (en) Erythromycin A 9-O-oximes derivatives, pharmaceutical composition on base thereof and method of treatment of infectious diseases
NL1003286A1 (nl) Bereiding van organische disulfiden.
AU2002214197A1 (en) Macrolides
MY115795A (en) Substituted benzenesulfonylureas and -thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them
HUP9801951A3 (en) New disubstituted trans 3,4,4,4a,5,6,10b-hexahydro-2h-napht-[1,2-b][1,4]-oxazine derivatives, process for producing them and pharmaceutical compositions containing them
AU3439899A (en) Tricyclic 3-keto derivatives of 6-o-methylerythromycin
AU5494696A (en) Bacterial mass production of paclitaxel
IT1271689B (it) 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
AU4883996A (en) Novel cyclic amino-indole piperazine derivatives, preparation process and utilization as medicaments
NO20030801L (no) Aminoalkenylbenzoyl-benzofuran- eller benzotiofenderivater, fremgangsmåte for deres fremstilling og preparater inneholdende de samme