HUP0004809A2 - Többgyűrűs eritromicin-származékok - Google Patents
Többgyűrűs eritromicin-származékokInfo
- Publication number
- HUP0004809A2 HUP0004809A2 HU0004809A HUP0004809A HUP0004809A2 HU P0004809 A2 HUP0004809 A2 HU P0004809A2 HU 0004809 A HU0004809 A HU 0004809A HU P0004809 A HUP0004809 A HU P0004809A HU P0004809 A2 HUP0004809 A2 HU P0004809A2
- Authority
- HU
- Hungary
- Prior art keywords
- erythromycin derivatives
- compounds
- antibacterial effect
- derivatives
- multicyclic
- Prior art date
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
- 229940041033 macrolides Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000003367 polycyclic group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
A találmány szemi-szintetikus makrolidokra, közelebbrőlkondenzált aromás és heterociklusos csoportokkal szubsztituáltantibakteriális hatású eritromicinszármazékokra, ilyen vegyületekettartalmazó gyógy- szerkészítményekre és a vegyületek előállításieljárására vonatkozik. A találmány szerinti többgyűrűseritromicinszármazékok fokozott antibakteriális hatásúak, arezisztencia kialakulása csökkent és nem várt módon szelektívekbizonyos mikroorganizmusokkal szemben. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86545397A | 1997-05-29 | 1997-05-29 | |
| PCT/US1998/010501 WO1998054197A1 (en) | 1997-05-29 | 1998-05-22 | Multicyclic erythromycin derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0004809A2 true HUP0004809A2 (hu) | 2001-05-28 |
| HUP0004809A3 HUP0004809A3 (en) | 2001-11-28 |
Family
ID=25345545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0004809A HUP0004809A3 (en) | 1997-05-29 | 1998-05-22 | Multicyclic erythromycin derivatives |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP0984975B1 (hu) |
| JP (1) | JP4368950B2 (hu) |
| KR (1) | KR20010013041A (hu) |
| CN (1) | CN1258299A (hu) |
| AR (1) | AR013081A1 (hu) |
| AT (1) | ATE238330T1 (hu) |
| AU (1) | AU7591298A (hu) |
| BG (1) | BG103985A (hu) |
| BR (1) | BR9809489A (hu) |
| CA (1) | CA2290421C (hu) |
| CO (1) | CO4950620A1 (hu) |
| DE (1) | DE69813798T2 (hu) |
| DK (1) | DK0984975T3 (hu) |
| ES (1) | ES2197472T3 (hu) |
| HU (1) | HUP0004809A3 (hu) |
| IL (1) | IL132482A0 (hu) |
| MX (1) | MXPA99011001A (hu) |
| NO (1) | NO995842L (hu) |
| NZ (1) | NZ500531A (hu) |
| PL (1) | PL337066A1 (hu) |
| PT (1) | PT984975E (hu) |
| SI (1) | SI0984975T1 (hu) |
| SK (1) | SK160299A3 (hu) |
| TR (1) | TR199902820T2 (hu) |
| WO (1) | WO1998054197A1 (hu) |
| ZA (1) | ZA984488B (hu) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003501439A (ja) * | 1999-06-07 | 2003-01-14 | アボット・ラボラトリーズ | ６−ｏ−カルバメートケトライド誘導体 |
| EP1841775A2 (en) * | 2005-01-12 | 2007-10-10 | Alpharma APS | Erythromycin derivatives as antibacterial agents |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5631355A (en) * | 1992-04-22 | 1997-05-20 | Taisho Pharmaceutical Co., Ltd. | 5-O-desosaminylerythronolide a derivatives |
| ES2218604T3 (es) * | 1995-11-08 | 2004-11-16 | Abbott Laboratories | Derivados triciclicos de eritromicina. |
-
1998
- 1998-05-22 SK SK1602-99A patent/SK160299A3/sk unknown
- 1998-05-22 JP JP50078099A patent/JP4368950B2/ja not_active Expired - Fee Related
- 1998-05-22 BR BR9809489-0A patent/BR9809489A/pt not_active IP Right Cessation
- 1998-05-22 DK DK98923678T patent/DK0984975T3/da active
- 1998-05-22 ES ES98923678T patent/ES2197472T3/es not_active Expired - Lifetime
- 1998-05-22 DE DE69813798T patent/DE69813798T2/de not_active Expired - Fee Related
- 1998-05-22 HU HU0004809A patent/HUP0004809A3/hu unknown
- 1998-05-22 CA CA002290421A patent/CA2290421C/en not_active Expired - Fee Related
- 1998-05-22 WO PCT/US1998/010501 patent/WO1998054197A1/en not_active Application Discontinuation
- 1998-05-22 CN CN98805510A patent/CN1258299A/zh active Pending
- 1998-05-22 TR TR1999/02820T patent/TR199902820T2/xx unknown
- 1998-05-22 PT PT98923678T patent/PT984975E/pt unknown
- 1998-05-22 AU AU75912/98A patent/AU7591298A/en not_active Abandoned
- 1998-05-22 IL IL13248298A patent/IL132482A0/xx unknown
- 1998-05-22 SI SI9830449T patent/SI0984975T1/xx unknown
- 1998-05-22 EP EP98923678A patent/EP0984975B1/en not_active Expired - Lifetime
- 1998-05-22 NZ NZ500531A patent/NZ500531A/en unknown
- 1998-05-22 PL PL98337066A patent/PL337066A1/xx unknown
- 1998-05-22 MX MXPA99011001A patent/MXPA99011001A/es not_active IP Right Cessation
- 1998-05-22 KR KR1019997011017A patent/KR20010013041A/ko not_active Application Discontinuation
- 1998-05-22 AT AT98923678T patent/ATE238330T1/de not_active IP Right Cessation
- 1998-05-26 ZA ZA984488A patent/ZA984488B/xx unknown
- 1998-05-27 CO CO98029719A patent/CO4950620A1/es unknown
- 1998-05-28 AR ARP980102489A patent/AR013081A1/es unknown
-
1999
- 1999-11-29 NO NO995842A patent/NO995842L/no not_active Application Discontinuation
- 1999-12-10 BG BG103985A patent/BG103985A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BG103985A (en) | 2000-07-31 |
| KR20010013041A (ko) | 2001-02-26 |
| NO995842D0 (no) | 1999-11-29 |
| ZA984488B (en) | 1998-12-02 |
| ES2197472T3 (es) | 2004-01-01 |
| NO995842L (no) | 2000-01-26 |
| TR199902820T2 (xx) | 2000-04-21 |
| EP0984975A1 (en) | 2000-03-15 |
| DE69813798D1 (en) | 2003-05-28 |
| SI0984975T1 (en) | 2004-02-29 |
| IL132482A0 (en) | 2001-03-19 |
| AR013081A1 (es) | 2000-12-13 |
| BR9809489A (pt) | 2000-06-20 |
| SK160299A3 (en) | 2000-06-12 |
| MXPA99011001A (es) | 2003-09-10 |
| WO1998054197A1 (en) | 1998-12-03 |
| JP2002500669A (ja) | 2002-01-08 |
| PT984975E (pt) | 2003-09-30 |
| CA2290421C (en) | 2007-05-08 |
| EP0984975B1 (en) | 2003-04-23 |
| NZ500531A (en) | 2001-07-27 |
| ATE238330T1 (de) | 2003-05-15 |
| CA2290421A1 (en) | 1998-12-03 |
| DK0984975T3 (da) | 2003-08-11 |
| PL337066A1 (en) | 2000-07-31 |
| JP4368950B2 (ja) | 2009-11-18 |
| AU7591298A (en) | 1998-12-30 |
| CN1258299A (zh) | 2000-06-28 |
| CO4950620A1 (es) | 2000-09-01 |
| DE69813798T2 (de) | 2004-02-19 |
| HUP0004809A3 (en) | 2001-11-28 |
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