HUP0003802A2 - 13-Dihidro-3'-aziridino-antraciklinek - Google Patents

13-Dihidro-3'-aziridino-antraciklinek

Info

Publication number
HUP0003802A2
HUP0003802A2 HU0003802A HUP0003802A HUP0003802A2 HU P0003802 A2 HUP0003802 A2 HU P0003802A2 HU 0003802 A HU0003802 A HU 0003802A HU P0003802 A HUP0003802 A HU P0003802A HU P0003802 A2 HUP0003802 A2 HU P0003802A2
Authority
HU
Hungary
Prior art keywords
compounds
aziridino
anthracyclines
dihydro
mixtures
Prior art date
Application number
HU0003802A
Other languages
English (en)
Inventor
Michele Caruso
Cristina Geroni
Marina Ripamonti
Antonino Suarato
Original Assignee
Pharmacia & Upjohn S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn S.P.A. filed Critical Pharmacia & Upjohn S.P.A.
Publication of HUP0003802A2 publication Critical patent/HUP0003802A2/hu
Publication of HUP0003802A3 publication Critical patent/HUP0003802A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A találmány tumorellenes hatóanyagokként alkalmazható (I) általánosképletű antraciklin-glikozidokra vonatkozik, \* (I) ahol a képletben ahullámvonal azt jelenti, hogy a 13-as pozícióban lévő hidroxicsoporta- vagy b-helyzetben, illetve ezek keverékeinek formájában lehet. Atalálmány kiterjed a vegyületek előállítási eljárására, a vegyületekettartalmazó gyógyszerkészítményekre, valamint a vegyületek gyógyászatialkalmazására is. Ó
HU0003802A 1998-04-15 1999-04-09 13-dihydro-3'-aziridino anthracyclines HUP0003802A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9808027.8A GB9808027D0 (en) 1998-04-15 1998-04-15 13-dihydro-3' aziridino anthracyclines
PCT/EP1999/002567 WO1999052921A1 (en) 1998-04-15 1999-04-09 13-dihydro-3'aziridino anthracyclines

Publications (2)

Publication Number Publication Date
HUP0003802A2 true HUP0003802A2 (hu) 2001-04-28
HUP0003802A3 HUP0003802A3 (en) 2003-05-28

Family

ID=10830403

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003802A HUP0003802A3 (en) 1998-04-15 1999-04-09 13-dihydro-3'-aziridino anthracyclines

Country Status (27)

Country Link
US (1) US6258786B1 (hu)
EP (1) EP0989989B1 (hu)
JP (1) JP2002505691A (hu)
KR (1) KR20010013772A (hu)
CN (1) CN1263532A (hu)
AR (1) AR019046A1 (hu)
AT (1) ATE230411T1 (hu)
AU (1) AU749578B2 (hu)
BR (1) BR9906305A (hu)
CA (1) CA2293453A1 (hu)
CZ (1) CZ292718B6 (hu)
DE (1) DE69904682T2 (hu)
DK (1) DK0989989T3 (hu)
EA (1) EA002161B1 (hu)
ES (1) ES2191430T3 (hu)
GB (1) GB9808027D0 (hu)
HU (1) HUP0003802A3 (hu)
ID (1) ID23006A (hu)
IL (1) IL133114A0 (hu)
MY (1) MY115486A (hu)
NO (1) NO314148B1 (hu)
NZ (1) NZ501931A (hu)
PL (1) PL337368A1 (hu)
TW (1) TW454012B (hu)
UA (1) UA45493C2 (hu)
WO (1) WO1999052921A1 (hu)
ZA (1) ZA997793B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0006601D0 (en) * 2000-03-17 2000-05-10 Pharmacia & Upjohn Spa Crystalline alkycycline derivative
AU2016229807B2 (en) * 2015-03-09 2020-10-29 Hidrate, Inc. Wireless drink container for monitoring hydration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604381A (en) * 1982-07-16 1986-08-05 Farmitalia Carlo Erba S.P.A. 4-demethoxy-13-dihydrodaunorubicin and use thereof
JPS59212499A (ja) * 1983-05-13 1984-12-01 アドリヤ・ラボラトリ−ズ・インコ−ポレ−テツド 抗腫瘍性抗生物質アントラサイクリンの４−デメトキシ−３′−デアミノ−３′（４−モリホリニル）誘導体
GB8614323D0 (en) * 1986-06-12 1986-07-16 Erba Farmitalia Anthracyclines
GB9325417D0 (en) * 1993-12-13 1994-02-16 Erba Carlo Spa 3'- aziridino-anthracycline derivatives

Also Published As

Publication number Publication date
ATE230411T1 (de) 2003-01-15
MY115486A (en) 2003-06-30
IL133114A0 (en) 2001-03-19
HUP0003802A3 (en) 2003-05-28
AR019046A1 (es) 2001-12-26
EA002161B1 (ru) 2001-12-24
AU749578B2 (en) 2002-06-27
CN1263532A (zh) 2000-08-16
EP0989989B1 (en) 2003-01-02
AU3817499A (en) 1999-11-01
UA45493C2 (uk) 2002-04-15
NO996127L (no) 1999-12-10
GB9808027D0 (en) 1998-06-17
CZ451299A3 (cs) 2000-05-17
TW454012B (en) 2001-09-11
BR9906305A (pt) 2000-06-20
JP2002505691A (ja) 2002-02-19
NO996127D0 (no) 1999-12-10
DK0989989T3 (da) 2003-05-05
NZ501931A (en) 2001-08-31
PL337368A1 (en) 2000-08-14
DE69904682D1 (de) 2003-02-06
ZA997793B (en) 2000-08-02
CA2293453A1 (en) 1999-10-21
ID23006A (id) 1999-12-30
EP0989989A1 (en) 2000-04-05
ES2191430T3 (es) 2003-09-01
DE69904682T2 (de) 2003-11-13
US6258786B1 (en) 2001-07-10
CZ292718B6 (cs) 2003-12-17
NO314148B1 (no) 2003-02-03
EA200000025A1 (ru) 2000-08-28
KR20010013772A (ko) 2001-02-26
WO1999052921A1 (en) 1999-10-21

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees