EA200000025A1 - 13-дигидро-3'-азиридиноантрациклины - Google Patents

13-дигидро-3'-азиридиноантрациклины

Info

Publication number
EA200000025A1
EA200000025A1 EA200000025A EA200000025A EA200000025A1 EA 200000025 A1 EA200000025 A1 EA 200000025A1 EA 200000025 A EA200000025 A EA 200000025A EA 200000025 A EA200000025 A EA 200000025A EA 200000025 A1 EA200000025 A1 EA 200000025A1
Authority
EA
Eurasian Patent Office
Prior art keywords
anthrazyclines
aziridino
dihydro
mixture
formula
Prior art date
Application number
EA200000025A
Other languages
English (en)
Other versions
EA002161B1 (ru
Inventor
Кристина Джерони
Марина Рипамонти
Микеле Карузо
Антонио Суарато
Original Assignee
Фармация Энд Апджон С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фармация Энд Апджон С.П.А. filed Critical Фармация Энд Апджон С.П.А.
Publication of EA200000025A1 publication Critical patent/EA200000025A1/ru
Publication of EA002161B1 publication Critical patent/EA002161B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Abstract

Антрациклингликозиды формулы (I), где волнистая линия означает, что гидроксильная группа в положении 13 может находиться в α- или β-положении или в виде их смеси, пригодные в качестве противоопухолевых средств.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200000025A 1998-04-15 1999-04-09 Антрациклингликозид, способ его получения, его применение и фармацевтическая композиция EA002161B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9808027.8A GB9808027D0 (en) 1998-04-15 1998-04-15 13-dihydro-3' aziridino anthracyclines
PCT/EP1999/002567 WO1999052921A1 (en) 1998-04-15 1999-04-09 13-dihydro-3'aziridino anthracyclines

Publications (2)

Publication Number Publication Date
EA200000025A1 true EA200000025A1 (ru) 2000-08-28
EA002161B1 EA002161B1 (ru) 2001-12-24

Family

ID=10830403

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200000025A EA002161B1 (ru) 1998-04-15 1999-04-09 Антрациклингликозид, способ его получения, его применение и фармацевтическая композиция

Country Status (27)

Country Link
US (1) US6258786B1 (ru)
EP (1) EP0989989B1 (ru)
JP (1) JP2002505691A (ru)
KR (1) KR20010013772A (ru)
CN (1) CN1263532A (ru)
AR (1) AR019046A1 (ru)
AT (1) ATE230411T1 (ru)
AU (1) AU749578B2 (ru)
BR (1) BR9906305A (ru)
CA (1) CA2293453A1 (ru)
CZ (1) CZ292718B6 (ru)
DE (1) DE69904682T2 (ru)
DK (1) DK0989989T3 (ru)
EA (1) EA002161B1 (ru)
ES (1) ES2191430T3 (ru)
GB (1) GB9808027D0 (ru)
HU (1) HUP0003802A3 (ru)
ID (1) ID23006A (ru)
IL (1) IL133114A0 (ru)
MY (1) MY115486A (ru)
NO (1) NO314148B1 (ru)
NZ (1) NZ501931A (ru)
PL (1) PL337368A1 (ru)
TW (1) TW454012B (ru)
UA (1) UA45493C2 (ru)
WO (1) WO1999052921A1 (ru)
ZA (1) ZA997793B (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0006601D0 (en) * 2000-03-17 2000-05-10 Pharmacia & Upjohn Spa Crystalline alkycycline derivative
AU2016229807B2 (en) * 2015-03-09 2020-10-29 Hidrate, Inc. Wireless drink container for monitoring hydration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604381A (en) * 1982-07-16 1986-08-05 Farmitalia Carlo Erba S.P.A. 4-demethoxy-13-dihydrodaunorubicin and use thereof
JPS59212499A (ja) * 1983-05-13 1984-12-01 アドリヤ・ラボラトリ−ズ・インコ−ポレ−テツド 抗腫瘍性抗生物質アントラサイクリンの４−デメトキシ−３′−デアミノ−３′（４−モリホリニル）誘導体
GB8614323D0 (en) * 1986-06-12 1986-07-16 Erba Farmitalia Anthracyclines
GB9325417D0 (en) * 1993-12-13 1994-02-16 Erba Carlo Spa 3'- aziridino-anthracycline derivatives

Also Published As

Publication number Publication date
AR019046A1 (es) 2001-12-26
ATE230411T1 (de) 2003-01-15
PL337368A1 (en) 2000-08-14
ZA997793B (en) 2000-08-02
AU749578B2 (en) 2002-06-27
CZ451299A3 (cs) 2000-05-17
WO1999052921A1 (en) 1999-10-21
IL133114A0 (en) 2001-03-19
EP0989989A1 (en) 2000-04-05
HUP0003802A3 (en) 2003-05-28
EA002161B1 (ru) 2001-12-24
CA2293453A1 (en) 1999-10-21
DE69904682T2 (de) 2003-11-13
BR9906305A (pt) 2000-06-20
US6258786B1 (en) 2001-07-10
NO996127L (no) 1999-12-10
NO314148B1 (no) 2003-02-03
TW454012B (en) 2001-09-11
GB9808027D0 (en) 1998-06-17
MY115486A (en) 2003-06-30
NZ501931A (en) 2001-08-31
CZ292718B6 (cs) 2003-12-17
CN1263532A (zh) 2000-08-16
KR20010013772A (ko) 2001-02-26
EP0989989B1 (en) 2003-01-02
DK0989989T3 (da) 2003-05-05
DE69904682D1 (de) 2003-02-06
UA45493C2 (uk) 2002-04-15
AU3817499A (en) 1999-11-01
JP2002505691A (ja) 2002-02-19
NO996127D0 (no) 1999-12-10
ID23006A (id) 1999-12-30
HUP0003802A2 (hu) 2001-04-28
ES2191430T3 (es) 2003-09-01

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY KZ RU