BR9906305A - 13-dihidro-3'aziridino antraciclinas - Google Patents

13-dihidro-3'aziridino antraciclinas

Info

Publication number
BR9906305A
BR9906305A BR9906305-0A BR9906305A BR9906305A BR 9906305 A BR9906305 A BR 9906305A BR 9906305 A BR9906305 A BR 9906305A BR 9906305 A BR9906305 A BR 9906305A
Authority
BR
Brazil
Prior art keywords
aziridino
anthracyclines
dihydro
antraciclinas
dihidro
Prior art date
Application number
BR9906305-0A
Other languages
English (en)
Inventor
Cristina Geroni
Michele Caruso
Antonio Suarato
Marina Ripamonti
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of BR9906305A publication Critical patent/BR9906305A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"13-DIHIDRO-3'AZIRIDINO ANTRACICLINAS". Trata-se de glicosídeos antraciclina de fórmula (I), onde a linha ondulada significa que o grupo hidróxi na posição 13 pode estar na posição <244> ou <225>, ou uma mistura das mesmas, que são úteis como agentes anti tumor.
BR9906305-0A 1998-04-15 1999-04-09 13-dihidro-3'aziridino antraciclinas BR9906305A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9808027.8A GB9808027D0 (en) 1998-04-15 1998-04-15 13-dihydro-3' aziridino anthracyclines
PCT/EP1999/002567 WO1999052921A1 (en) 1998-04-15 1999-04-09 13-dihydro-3'aziridino anthracyclines

Publications (1)

Publication Number Publication Date
BR9906305A true BR9906305A (pt) 2000-06-20

Family

ID=10830403

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9906305-0A BR9906305A (pt) 1998-04-15 1999-04-09 13-dihidro-3'aziridino antraciclinas

Country Status (27)

Country Link
US (1) US6258786B1 (pt)
EP (1) EP0989989B1 (pt)
JP (1) JP2002505691A (pt)
KR (1) KR20010013772A (pt)
CN (1) CN1263532A (pt)
AR (1) AR019046A1 (pt)
AT (1) ATE230411T1 (pt)
AU (1) AU749578B2 (pt)
BR (1) BR9906305A (pt)
CA (1) CA2293453A1 (pt)
CZ (1) CZ292718B6 (pt)
DE (1) DE69904682T2 (pt)
DK (1) DK0989989T3 (pt)
EA (1) EA002161B1 (pt)
ES (1) ES2191430T3 (pt)
GB (1) GB9808027D0 (pt)
HU (1) HUP0003802A3 (pt)
ID (1) ID23006A (pt)
IL (1) IL133114A0 (pt)
MY (1) MY115486A (pt)
NO (1) NO314148B1 (pt)
NZ (1) NZ501931A (pt)
PL (1) PL337368A1 (pt)
TW (1) TW454012B (pt)
UA (1) UA45493C2 (pt)
WO (1) WO1999052921A1 (pt)
ZA (1) ZA997793B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0006601D0 (en) * 2000-03-17 2000-05-10 Pharmacia & Upjohn Spa Crystalline alkycycline derivative
AU2016229807B2 (en) * 2015-03-09 2020-10-29 Hidrate, Inc. Wireless drink container for monitoring hydration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604381A (en) * 1982-07-16 1986-08-05 Farmitalia Carlo Erba S.P.A. 4-demethoxy-13-dihydrodaunorubicin and use thereof
JPS59212499A (ja) * 1983-05-13 1984-12-01 アドリヤ・ラボラトリ−ズ・インコ−ポレ−テツド 抗腫瘍性抗生物質アントラサイクリンの４−デメトキシ−３′−デアミノ−３′（４−モリホリニル）誘導体
GB8614323D0 (en) * 1986-06-12 1986-07-16 Erba Farmitalia Anthracyclines
GB9325417D0 (en) * 1993-12-13 1994-02-16 Erba Carlo Spa 3'- aziridino-anthracycline derivatives

Also Published As

Publication number Publication date
ATE230411T1 (de) 2003-01-15
MY115486A (en) 2003-06-30
IL133114A0 (en) 2001-03-19
HUP0003802A3 (en) 2003-05-28
AR019046A1 (es) 2001-12-26
EA002161B1 (ru) 2001-12-24
AU749578B2 (en) 2002-06-27
CN1263532A (zh) 2000-08-16
HUP0003802A2 (hu) 2001-04-28
EP0989989B1 (en) 2003-01-02
AU3817499A (en) 1999-11-01
UA45493C2 (uk) 2002-04-15
NO996127L (no) 1999-12-10
GB9808027D0 (en) 1998-06-17
CZ451299A3 (cs) 2000-05-17
TW454012B (en) 2001-09-11
JP2002505691A (ja) 2002-02-19
NO996127D0 (no) 1999-12-10
DK0989989T3 (da) 2003-05-05
NZ501931A (en) 2001-08-31
PL337368A1 (en) 2000-08-14
DE69904682D1 (de) 2003-02-06
ZA997793B (en) 2000-08-02
CA2293453A1 (en) 1999-10-21
ID23006A (id) 1999-12-30
EP0989989A1 (en) 2000-04-05
ES2191430T3 (es) 2003-09-01
DE69904682T2 (de) 2003-11-13
US6258786B1 (en) 2001-07-10
CZ292718B6 (cs) 2003-12-17
NO314148B1 (no) 2003-02-03
EA200000025A1 (ru) 2000-08-28
KR20010013772A (ko) 2001-02-26
WO1999052921A1 (en) 1999-10-21

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. PORTANTO, INDEFIRO O PRESENTE PEDIDO DE PATENTE COMO INVENCAO - DE ACORDO COM OS ARTS. 8O E 10 (VIII) DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.