WO2003030884A3 - Use of solasonine for the treatment of skin tumors - Google Patents

Use of solasonine for the treatment of skin tumors Download PDF

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Publication number
WO2003030884A3
WO2003030884A3 PCT/EP2002/011317 EP0211317W WO03030884A3 WO 2003030884 A3 WO2003030884 A3 WO 2003030884A3 EP 0211317 W EP0211317 W EP 0211317W WO 03030884 A3 WO03030884 A3 WO 03030884A3
Authority
WO
WIPO (PCT)
Prior art keywords
solasonine
treatment
skin tumors
tumors
en3β
Prior art date
Application number
PCT/EP2002/011317
Other languages
French (fr)
Other versions
WO2003030884A2 (en
Inventor
Chris Lawson
Original Assignee
Glycomed Sciences Ltd
Chris Lawson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycomed Sciences Ltd, Chris Lawson filed Critical Glycomed Sciences Ltd
Priority to AU2002350513A priority Critical patent/AU2002350513A1/en
Publication of WO2003030884A2 publication Critical patent/WO2003030884A2/en
Publication of WO2003030884A3 publication Critical patent/WO2003030884A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to the use of the triglycoside (22R, 25R)-spiro-5-en3β-yl-α-L-rhamnopyranosyl-(1→2gal)-O-p-D-glucopyranosyl-(1→3gal)-β-D-galactopyranose for the preparation of pharmaceutical compositions for treating skin tumors.
PCT/EP2002/011317 2001-10-09 2002-10-09 Use of solasonine for the treatment of skin tumors WO2003030884A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002350513A AU2002350513A1 (en) 2001-10-09 2002-10-09 Use of solasonine for the treatment of skin tumors

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01124675 2001-10-09
EP01124675.8 2001-10-09

Publications (2)

Publication Number Publication Date
WO2003030884A2 WO2003030884A2 (en) 2003-04-17
WO2003030884A3 true WO2003030884A3 (en) 2003-09-04

Family

ID=8178980

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/011317 WO2003030884A2 (en) 2001-10-09 2002-10-09 Use of solasonine for the treatment of skin tumors

Country Status (2)

Country Link
AU (1) AU2002350513A1 (en)
WO (1) WO2003030884A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2529358A1 (en) * 2003-07-08 2005-01-20 Glycomed Sciences Limited Steroid modified solatrioses
TWI476012B (en) 2011-05-12 2015-03-11 G & E Herbal Biotechnology Co Ltd Treatment and/or prevention of inflammation and cutaneous photodamage and photoprotection of the skin with a water soluble extract from plant of solanum genus

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0020029A1 (en) * 1979-05-02 1980-12-10 Aruba (Qld.) Pty. Ltd. Pharmaceutical compositions comprising steroid alkaloids
WO1991010743A1 (en) * 1990-01-18 1991-07-25 Cura Nominees Pty Ltd Glycoalkaloids
WO2000061153A1 (en) * 1999-04-09 2000-10-19 Cura Nominees Pty. Ltd. Medicinal compositions and their method of preparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0020029A1 (en) * 1979-05-02 1980-12-10 Aruba (Qld.) Pty. Ltd. Pharmaceutical compositions comprising steroid alkaloids
WO1991010743A1 (en) * 1990-01-18 1991-07-25 Cura Nominees Pty Ltd Glycoalkaloids
WO2000061153A1 (en) * 1999-04-09 2000-10-19 Cura Nominees Pty. Ltd. Medicinal compositions and their method of preparation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHAM B E ET AL: "TOPICAL TREATMENT OF MALIGNANT AND PREMALIGNANT SKIN LESIONS BY VERY LOW CONCENTRATIONS OF A STANDARD MIXTURE (BEC) OF SOLASODINE GLYCOSIDES", CANCER LETTERS, NEW YORK, NY, US, vol. 59, 1991, pages 183 - 192, XP001077064, ISSN: 0304-3835 *
CHAM B E: "SOLASODINE GLYCOSIDES AS ANTI-CANCER AGENTS: PRE-CLINICAL AND CLINICAL STUDIES", ASIA PACIFIC JOURNAL OF PHARMACOLOGY, SINGAPORE UNIVERSITY PRESS, SG, vol. 9, 1994, pages 113 - 118, XP002950616, ISSN: 0217-9687 *
CHEM B E ET AL: "GLYCOALKALOIDS FROM SOLANUM SODOMAEUM ARE EFFECTIVE IN THE TREATMENT OF SKIN CANCERS IN MAN", CANCER LETTERS, NEW YORK, NY, US, vol. 36, 1987, pages 111 - 118, XP002950615, ISSN: 0304-3835 *

Also Published As

Publication number Publication date
AU2002350513A1 (en) 2003-04-22
WO2003030884A2 (en) 2003-04-17

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