WO2001068661A3 - Crystalline alkycycline derivative - Google Patents

Crystalline alkycycline derivative Download PDF

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Publication number
WO2001068661A3
WO2001068661A3 PCT/EP2001/002783 EP0102783W WO0168661A3 WO 2001068661 A3 WO2001068661 A3 WO 2001068661A3 EP 0102783 W EP0102783 W EP 0102783W WO 0168661 A3 WO0168661 A3 WO 0168661A3
Authority
WO
WIPO (PCT)
Prior art keywords
crystalline
alkycycline
derivative
preparation
deamino
Prior art date
Application number
PCT/EP2001/002783
Other languages
French (fr)
Other versions
WO2001068661A2 (en
WO2001068661A9 (en
Inventor
Attilio Tomasi
Mario Ungari
Mauro Galli
Paolo Fumagalli
Original Assignee
Pharmacia & Upjohn Spa
Attilio Tomasi
Mario Ungari
Mauro Galli
Paolo Fumagalli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa, Attilio Tomasi, Mario Ungari, Mauro Galli, Paolo Fumagalli filed Critical Pharmacia & Upjohn Spa
Priority to AU2001263789A priority Critical patent/AU2001263789A1/en
Publication of WO2001068661A2 publication Critical patent/WO2001068661A2/en
Publication of WO2001068661A3 publication Critical patent/WO2001068661A3/en
Publication of WO2001068661A9 publication Critical patent/WO2001068661A9/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

There is provided the crystalline form of 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methansulfonyl daunorubicin, the preparation thereof and its use in the preparation of pharmaceutical composition for the treatment of tumors.
PCT/EP2001/002783 2000-03-17 2001-03-12 Crystalline alkycycline derivative WO2001068661A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001263789A AU2001263789A1 (en) 2000-03-17 2001-03-12 Crystalline alkycycline derivative

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0006601.9 2000-03-17
GB0006601A GB0006601D0 (en) 2000-03-17 2000-03-17 Crystalline alkycycline derivative

Publications (3)

Publication Number Publication Date
WO2001068661A2 WO2001068661A2 (en) 2001-09-20
WO2001068661A3 true WO2001068661A3 (en) 2002-03-21
WO2001068661A9 WO2001068661A9 (en) 2003-05-22

Family

ID=9887931

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/002783 WO2001068661A2 (en) 2000-03-17 2001-03-12 Crystalline alkycycline derivative

Country Status (3)

Country Link
AU (1) AU2001263789A1 (en)
GB (1) GB0006601D0 (en)
WO (1) WO2001068661A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0117403D0 (en) * 2001-07-17 2001-09-05 Pharmacia & Upjohn Spa Solvent-free crystalline anthracycline derivatives

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532218A (en) * 1993-12-13 1996-07-02 Farmitalia Carlo Erba S.R.L. 3'-aziridino-anthracycline derivatives
WO1999052921A1 (en) * 1998-04-15 1999-10-21 Pharmacia & Upjohn S.P.A. 13-dihydro-3'aziridino anthracyclines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532218A (en) * 1993-12-13 1996-07-02 Farmitalia Carlo Erba S.R.L. 3'-aziridino-anthracycline derivatives
WO1999052921A1 (en) * 1998-04-15 1999-10-21 Pharmacia & Upjohn S.P.A. 13-dihydro-3'aziridino anthracyclines

Also Published As

Publication number Publication date
WO2001068661A2 (en) 2001-09-20
AU2001263789A1 (en) 2001-09-24
WO2001068661A9 (en) 2003-05-22
GB0006601D0 (en) 2000-05-10

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