HUP0003413A3 - New fused pyridine derivatives, process for their preparation and pharmaceutical compositions containing them - Google Patents

New fused pyridine derivatives, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
HUP0003413A3
HUP0003413A3 HU0003413A HUP0003413A HUP0003413A3 HU P0003413 A3 HUP0003413 A3 HU P0003413A3 HU 0003413 A HU0003413 A HU 0003413A HU P0003413 A HUP0003413 A HU P0003413A HU P0003413 A3 HUP0003413 A3 HU P0003413A3
Authority
HU
Hungary
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
pyridine derivatives
fused pyridine
Prior art date
Application number
HU0003413A
Other languages
English (en)
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of HU0003413D0 publication Critical patent/HU0003413D0/hu
Publication of HUP0003413A2 publication Critical patent/HUP0003413A2/hu
Publication of HUP0003413A3 publication Critical patent/HUP0003413A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU0003413A 1999-08-27 2000-08-25 New fused pyridine derivatives, process for their preparation and pharmaceutical compositions containing them HUP0003413A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9910834A FR2797874B1 (fr) 1999-08-27 1999-08-27 Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number Publication Date
HU0003413D0 HU0003413D0 (en) 2000-08-25
HUP0003413A2 HUP0003413A2 (hu) 2001-07-30
HUP0003413A3 true HUP0003413A3 (en) 2003-11-28

Family

ID=9549376

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003413A HUP0003413A3 (en) 1999-08-27 2000-08-25 New fused pyridine derivatives, process for their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (2) US6399616B1 (hu)
EP (1) EP1078928B1 (hu)
JP (1) JP3602780B2 (hu)
KR (1) KR100450317B1 (hu)
CN (1) CN1163495C (hu)
AT (1) ATE266664T1 (hu)
AU (1) AU765661B2 (hu)
BR (1) BR0003848A (hu)
CA (1) CA2317053A1 (hu)
DE (1) DE60010596T2 (hu)
DK (1) DK1078928T3 (hu)
EA (1) EA004102B1 (hu)
ES (1) ES2220359T3 (hu)
FR (1) FR2797874B1 (hu)
HK (1) HK1034250A1 (hu)
HU (1) HUP0003413A3 (hu)
MX (1) MXPA00008241A (hu)
NO (1) NO316651B1 (hu)
NZ (1) NZ506560A (hu)
PL (1) PL342178A1 (hu)
PT (1) PT1078928E (hu)
SI (1) SI1078928T1 (hu)
ZA (1) ZA200004411B (hu)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2797874B1 (fr) * 1999-08-27 2002-03-29 Adir Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE10031391A1 (de) * 2000-07-03 2002-02-07 Knoll Ag Bicyclische Verbindungen und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
AU2002242996A1 (en) * 2001-03-29 2002-10-15 Tanabe Seiyaku Co., Ltd. Spiroisoquinoline compounds, methods for their preparation and intermediates
DE10217006A1 (de) * 2002-04-16 2003-11-06 Merck Patent Gmbh Substituierte Indole
CA2508290C (en) * 2002-12-20 2017-02-28 Ciba Specialty Chemicals Holding Inc. Synthesis of amines and intermediates for the synthesis thereof
JP4559749B2 (ja) * 2004-02-16 2010-10-13 あすか製薬株式会社 ピペラジニルピリジン誘導体
JP4596792B2 (ja) * 2004-02-24 2010-12-15 あすか製薬株式会社 ５−ｈｔ１ａ作動作用と５−ｈｔ３拮抗作用を併有する薬剤
CA2557541C (en) 2004-02-26 2014-12-16 Aska Pharmaceutical Co., Ltd. Pyrimidine derivatives
DE102004023508A1 (de) * 2004-05-10 2005-12-08 Grünenthal GmbH Säurederivate substituierter Cyclohexyl-1,4-diamine
DE102004023501A1 (de) * 2004-05-10 2005-12-01 Grünenthal GmbH Oxosubstituierte Cyclohexyl-1,4-diamin-Derivate
DE102004023506A1 (de) * 2004-05-10 2005-12-01 Grünenthal GmbH Kettenverlängerte substituierte Cyclohexyl-1,4-diamin-Derivate
WO2006008192A1 (en) * 2004-07-23 2006-01-26 Bayer Cropscience Sa N-[2-(4-pyridinyl)ethyl]benzamide derivatives as fungicides
US7635696B2 (en) 2004-11-26 2009-12-22 Janssen Pharmaceutica N.V. Isoxazoline-indole derivatives with an improved antipsychotic and anxiolytic activity
FR2909670B1 (fr) 2006-12-12 2010-07-30 Sanofi Aventis Derive fluore de quinoleine-2(1h)-one,son procede de preparation et son utilisation comme intermediaire de synthese
CN104337812B (zh) 2013-07-29 2018-09-14 广东东阳光药业有限公司 取代的杂芳基化合物及其使用方法和用途
CA2933466A1 (en) * 2013-12-13 2015-06-18 Takeda Pharmaceutical Company Limited Pyrrolo[3,2-c]pyridine derivatives as tlr inhibitors
US9968604B2 (en) 2015-04-16 2018-05-15 Chiesi Farmaceutici S.P.A. Chromene derivatives as phoshoinositide 3-kinases inhibitors
CN106243088B (zh) 2015-06-03 2019-01-04 广东东阳光药业有限公司 取代的哌嗪化合物及其使用方法和用途
CN106795160B (zh) * 2015-07-23 2019-04-19 广东东阳光药业有限公司 取代的吲哚化合物及其使用方法和用途
EP4308119A1 (en) * 2021-03-19 2024-01-24 Centre National de la Recherche Scientifique <sup2/>? <sub2/>?7?applications of biased ligands of the serotonin 5-htreceptor for the treatment of pain, multiple sclerosis and the control of thermoregulation

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2761068A (en) * 1953-10-15 1956-08-28 Gen Electric Automatic pole figure recorder
FR2312498A1 (fr) * 1975-05-30 1976-12-24 Parcor Procede de preparation de la thieno (3,2-c) pyridine et de derives de celle-ci
FR2395271A1 (fr) * 1977-06-21 1979-01-19 Parcor Procede de preparation de thieno (2,3-c) et thieno (3,2-c) pyridines
KR830003481A (ko) * 1980-09-22 1983-06-20 미야다께 도꾸지로 6-플루오로-1,8-나프티리딘 유도체의 제조방법
AU553415B2 (en) * 1983-09-19 1986-07-17 Abbott Japan Co., Ltd. 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids
CA1278792C (en) * 1985-05-06 1991-01-08 Joseph P. Yevich Antipsychotic fused-ring pyridinylpiperazine derivatives
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
JP2815126B2 (ja) * 1990-08-31 1998-10-27 日清製粉株式会社 ピリジンカルボン酸アミド誘導体
US5681954A (en) * 1993-05-14 1997-10-28 Daiichi Pharmaceutical Co., Ltd. Piperazine derivatives
US5300498A (en) * 1993-06-04 1994-04-05 Hoechst-Roussel Pharmaceuticals Incorporated 6-piperazinyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acids, esters, amides and related compounds
FR2721800B1 (fr) * 1994-07-01 1997-12-26 Roussel Uclaf Nouveaux concentres emulsionnables renfermant un u plussieurs pesticides
JPH10502364A (ja) * 1994-07-06 1998-03-03 クウエスト・インターナシヨナル・ベー・ベー 昆虫誘引剤としてのリンゴ酸ジブチルの使用
DE4447770C2 (de) * 1994-08-20 2002-12-19 Max Delbrueck Centrum Verfahren zur Herstellung von liposomal verkapseltem Taxol
CZ288149B6 (en) * 1995-09-15 2001-05-16 Sanofi Synthelabo Derivatives of 2(1H)-quinolone, process of their preparation and pharmaceutical preparation in which they are comprised
FR2738823B1 (fr) * 1995-09-15 1997-10-31 Synthelabo Derives de 3-(omega-(4-(thieno(3,2-c)pyridin-4-yl)piperazin- 1-yl)alkyl)-3,4-dihydroquinolein-2(1h)-one,leur preparation et leur application en therapeutique
FR2761071B1 (fr) * 1997-03-20 1999-12-03 Synthelabo Derives de quinolein-2(1h)-one et de dihydroquinolein-2(1h)- one, leur preparation et leur application en therapeutique
FR2761068B1 (fr) * 1997-03-20 1999-04-23 Synthelabo Derives de piperazin-4-ylthieno[3,2-c]pyridin-4-yl-2- carboxamide, leur preparation et leur application en therapeutique
EP1020445B1 (en) * 1997-10-02 2008-08-13 Eisai R&D Management Co., Ltd. Fused pyridine derivatives
FR2797874B1 (fr) * 1999-08-27 2002-03-29 Adir Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
JP3602780B2 (ja) 2004-12-15
FR2797874A1 (fr) 2001-03-02
NO20004295D0 (no) 2000-08-28
HU0003413D0 (en) 2000-08-25
EA200000792A3 (ru) 2001-06-25
EP1078928A1 (fr) 2001-02-28
CN1286255A (zh) 2001-03-07
SI1078928T1 (en) 2004-08-31
MXPA00008241A (es) 2002-08-20
HK1034250A1 (en) 2001-10-19
ATE266664T1 (de) 2004-05-15
US6486171B2 (en) 2002-11-26
KR100450317B1 (ko) 2004-09-30
PL342178A1 (en) 2001-03-12
NO316651B1 (no) 2004-03-22
EA004102B1 (ru) 2003-12-25
DK1078928T3 (da) 2004-09-13
ZA200004411B (en) 2001-02-28
JP2001097978A (ja) 2001-04-10
KR20010050228A (ko) 2001-06-15
US6399616B1 (en) 2002-06-04
CA2317053A1 (fr) 2001-02-27
EP1078928B1 (fr) 2004-05-12
DE60010596T2 (de) 2005-05-19
NZ506560A (en) 2001-06-29
AU5364200A (en) 2001-03-01
FR2797874B1 (fr) 2002-03-29
ES2220359T3 (es) 2004-12-16
HUP0003413A2 (hu) 2001-07-30
DE60010596D1 (de) 2004-06-17
EA200000792A2 (ru) 2001-04-23
US20020161228A1 (en) 2002-10-31
CN1163495C (zh) 2004-08-25
PT1078928E (pt) 2004-09-30
AU765661B2 (en) 2003-09-25
NO20004295L (no) 2001-02-28
BR0003848A (pt) 2001-04-03

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees