HUP0001222A3 - Imino-aza-anthracyclinone derivatives, pharmaceutical compositions thereof against amyloidosis and process for preparing them - Google Patents
Imino-aza-anthracyclinone derivatives, pharmaceutical compositions thereof against amyloidosis and process for preparing themInfo
- Publication number
- HUP0001222A3 HUP0001222A3 HU0001222A HUP0001222A HUP0001222A3 HU P0001222 A3 HUP0001222 A3 HU P0001222A3 HU 0001222 A HU0001222 A HU 0001222A HU P0001222 A HUP0001222 A HU P0001222A HU P0001222 A3 HUP0001222 A3 HU P0001222A3
- Authority
- HU
- Hungary
- Prior art keywords
- aza
- imino
- preparing
- pharmaceutical compositions
- anthracyclinone derivatives
- Prior art date
Links
- 206010002022 amyloidosis Diseases 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9701628.1A GB9701628D0 (en) | 1997-01-27 | 1997-01-27 | Imino-aza-anthracyclinone derivatives |
PCT/EP1998/000152 WO1998032754A1 (en) | 1997-01-27 | 1998-01-09 | Imino-aza-anthracyclinone derivatives for the treatment of amyloidosis |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0001222A2 HUP0001222A2 (hu) | 2000-10-28 |
HUP0001222A3 true HUP0001222A3 (en) | 2001-01-29 |
Family
ID=10806639
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0001222A HUP0001222A3 (en) | 1997-01-27 | 1998-01-09 | Imino-aza-anthracyclinone derivatives, pharmaceutical compositions thereof against amyloidosis and process for preparing them |
Country Status (25)
Country | Link |
---|---|
US (1) | US6194422B1 (hu) |
EP (1) | EP0970080B1 (hu) |
JP (1) | JP2001511123A (hu) |
KR (1) | KR20000070483A (hu) |
CN (1) | CN1103774C (hu) |
AR (1) | AR011572A1 (hu) |
AT (1) | ATE235494T1 (hu) |
AU (1) | AU745981B2 (hu) |
BR (1) | BR9815448A (hu) |
CA (1) | CA2277951C (hu) |
DE (1) | DE69812599T2 (hu) |
DK (1) | DK0970080T3 (hu) |
EA (1) | EA001887B1 (hu) |
ES (1) | ES2195313T3 (hu) |
GB (1) | GB9701628D0 (hu) |
HU (1) | HUP0001222A3 (hu) |
IL (1) | IL130831A (hu) |
NO (1) | NO313198B1 (hu) |
NZ (1) | NZ337221A (hu) |
PL (1) | PL190304B1 (hu) |
PT (1) | PT970080E (hu) |
TW (1) | TW519544B (hu) |
UA (1) | UA57063C2 (hu) |
WO (1) | WO1998032754A1 (hu) |
ZA (1) | ZA98611B (hu) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9902938D0 (en) * | 1999-02-10 | 1999-03-31 | Novartis Ag | Organic compounds |
GB9911804D0 (en) * | 1999-05-20 | 1999-07-21 | Merck Sharp & Dohme | Therapeutic combination |
US7053191B2 (en) * | 2003-05-21 | 2006-05-30 | Solux Corporation | Method of preparing 4-R-substituted 4-demethoxydaunorubicin |
US8357785B2 (en) * | 2008-01-08 | 2013-01-22 | Solux Corporation | Method of aralkylation of 4′-hydroxyl group of anthracylins |
US9376406B2 (en) | 2011-03-03 | 2016-06-28 | Indiana University Research And Technology Corporation | uPAR-uPA interaction inhibitors and methods for treating cancer |
US8846882B2 (en) | 2011-04-29 | 2014-09-30 | Synbias Pharma Ag | Method of producing 4-demethoxydaunorubicin |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2258652A (en) * | 1991-08-15 | 1993-02-17 | Merck Sharp & Dohme | Pharmaceutically useful azabicyclic oxime ethers |
GB9416007D0 (en) * | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Anthracyclinone derivatives |
GB9418260D0 (en) * | 1994-09-09 | 1994-10-26 | Erba Carlo Spa | Anthracycline derivatives |
GB9516349D0 (en) * | 1995-08-09 | 1995-10-11 | Pharmacia Spa | Aza-anthracyclinone derivatives |
-
1997
- 1997-01-27 GB GBGB9701628.1A patent/GB9701628D0/en active Pending
- 1997-12-10 TW TW086118863A patent/TW519544B/zh active
-
1998
- 1998-01-09 WO PCT/EP1998/000152 patent/WO1998032754A1/en not_active Application Discontinuation
- 1998-01-09 DK DK98901964T patent/DK0970080T3/da active
- 1998-01-09 BR BR9815448-6A patent/BR9815448A/pt not_active Application Discontinuation
- 1998-01-09 US US09/341,703 patent/US6194422B1/en not_active Expired - Fee Related
- 1998-01-09 HU HU0001222A patent/HUP0001222A3/hu unknown
- 1998-01-09 PT PT98901964T patent/PT970080E/pt unknown
- 1998-01-09 PL PL98334803A patent/PL190304B1/pl not_active IP Right Cessation
- 1998-01-09 KR KR1019997006726A patent/KR20000070483A/ko not_active Application Discontinuation
- 1998-01-09 EA EA199900684A patent/EA001887B1/ru not_active IP Right Cessation
- 1998-01-09 ES ES98901964T patent/ES2195313T3/es not_active Expired - Lifetime
- 1998-01-09 DE DE69812599T patent/DE69812599T2/de not_active Expired - Fee Related
- 1998-01-09 NZ NZ337221A patent/NZ337221A/xx unknown
- 1998-01-09 IL IL13083198A patent/IL130831A/xx not_active IP Right Cessation
- 1998-01-09 EP EP98901964A patent/EP0970080B1/en not_active Expired - Lifetime
- 1998-01-09 AT AT98901964T patent/ATE235494T1/de not_active IP Right Cessation
- 1998-01-09 CN CN98802091A patent/CN1103774C/zh not_active Expired - Fee Related
- 1998-01-09 JP JP53153498A patent/JP2001511123A/ja not_active Withdrawn
- 1998-01-09 AU AU58633/98A patent/AU745981B2/en not_active Ceased
- 1998-01-09 CA CA002277951A patent/CA2277951C/en not_active Expired - Fee Related
- 1998-01-26 AR ARP980100326A patent/AR011572A1/es unknown
- 1998-01-26 ZA ZA98611A patent/ZA98611B/xx unknown
- 1998-09-01 UA UA99084831A patent/UA57063C2/uk unknown
-
1999
- 1999-07-20 NO NO19993549A patent/NO313198B1/no unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP0100431A3 (en) | Adamantana derivatives, pharmaceutical compositions comprising them and process for preparing them | |
HUP9700358A3 (en) | New oxazolidinon derivatives, process for their preparation and pharmaceutical compositions containing them | |
IL135920A0 (en) | 2-aryl -8-oxodihydropurine derivative, process for the preparation thereof, pharmaceutical composition containing the same and intermediate therefor | |
HUP0001508A3 (en) | 4-arylmethylene-2-imino-2,3-dihydrothiazole derivatives, their use, process for the preparation thereof and pharmaceutical compositions containing them | |
HUP0001555A3 (en) | Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation | |
HUP0004024A3 (en) | Azabenzimidazole-based compounds, process for their preparation and pharmaceutical composition thereof | |
HUP9900974A3 (en) | Heterocycle-condensed morphinoid derivatives, process for the preparation thereof, their use and pharmaceutical compositions containing them | |
IL127798A (en) | N-substituted indol-3-glyoxylamides, process for their preparation and pharmaceutical compositions comprising them | |
HUT73772A (en) | Novel erythromycin derivatives, method for preparing same and pharmaceutical compositions containing the same | |
HUP0001652A3 (en) | Oxadiazole derivatives, processes for their preparation, their use and pharmaceutical compositions containing them | |
HUP0102307A3 (en) | Bispidine derivatives, process for their preparation, pharmaceutical compositions thereof and intermediates | |
IL126787A (en) | D-proline derivatives, medicaments against amyloidosis comprising them and a process for their preparation | |
HUP0000941A3 (en) | Sulfamide derivatives, process for producing them, pharmaceutical compositions containing them and their use | |
HUP9900056A2 (hu) | Szubsztituált 4-fenil-amino-tiazol-származékok, eljárás előállításukra és ilyen vegyületeket tartalmazó gyógyászati készítmények | |
HUP0000426A3 (en) | Novel benzonaphthyridines, pharmaceutical compositions and use thereof and process for their preparation | |
HUP9700574A3 (en) | N,n-dimethyl-(3-aryl-but-3-ene)-amine derivatives, pharmaceutical compositions containing them and process for the preparation thereof | |
HUP9901739A3 (en) | Aminoisoquinolines and aminothienopyridine derivatives, process for producing thereof and pharmaceutical compositions containing them | |
HUP9800555A3 (en) | 3,3-diphenylallylamine derivatives and process for their preparation | |
IL113103A0 (en) | Piperidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same | |
HUP0002300A3 (en) | Quinoline-4-carboxamide derivatives, process for producing them, pharmaceutical compositions containing them and their use | |
HUP9901485A3 (en) | Heterocyclylcarboxamide derivatives, pharmaceutical compositions containing the same, process for their preparation and their use | |
HUP0001093A3 (en) | Oxazolidines as 5-ht2a-antagonists, pharmaceutical compositions containing the same and process for their preparation | |
HUP0001827A3 (en) | Colchicine derivatives, process for producing them, pharmaceutical compositions containing them, and use thereof for producing pharmaceutical compositions | |
HUT75112A (en) | Oxathiolanes, method for their preparation and pharmaceutical compositions contating same | |
HUP0101234A3 (en) | Betha-carboline derivatives, process for their preparation and pharmaceutical compositions thereof |