HUE065010T2 - Gyógyszerként alkalmas benzazepin származékok - Google Patents
Gyógyszerként alkalmas benzazepin származékokInfo
- Publication number
- HUE065010T2 HUE065010T2 HUE22164702A HUE22164702A HUE065010T2 HU E065010 T2 HUE065010 T2 HU E065010T2 HU E22164702 A HUE22164702 A HU E22164702A HU E22164702 A HUE22164702 A HU E22164702A HU E065010 T2 HUE065010 T2 HU E065010T2
- Authority
- HU
- Hungary
- Prior art keywords
- medicaments
- derivatives useful
- benzazepine derivatives
- benzazepine
- useful
- Prior art date
Links
- 150000008038 benzoazepines Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2017/024211 WO2019003433A1 (ja) | 2017-06-30 | 2017-06-30 | ベンゾアゼピン誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE065010T2 true HUE065010T2 (hu) | 2024-04-28 |
Family
ID=62976113
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE18743103A HUE060855T2 (hu) | 2017-06-30 | 2018-06-29 | Benzazepin származékok |
| HUE22164702A HUE065010T2 (hu) | 2017-06-30 | 2018-06-29 | Gyógyszerként alkalmas benzazepin származékok |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE18743103A HUE060855T2 (hu) | 2017-06-30 | 2018-06-29 | Benzazepin származékok |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US10889570B2 (hu) |
| EP (2) | EP4056557B1 (hu) |
| JP (2) | JP6688436B2 (hu) |
| KR (1) | KR102632228B1 (hu) |
| CN (1) | CN110891939A (hu) |
| AU (1) | AU2018293081B2 (hu) |
| BR (1) | BR112019027678A2 (hu) |
| CA (1) | CA3068396A1 (hu) |
| DK (2) | DK4056557T3 (hu) |
| EA (1) | EA202090131A1 (hu) |
| ES (2) | ES2964569T3 (hu) |
| FI (1) | FI4056557T3 (hu) |
| HR (2) | HRP20231616T1 (hu) |
| HU (2) | HUE060855T2 (hu) |
| IL (1) | IL271665B2 (hu) |
| LT (2) | LT4056557T (hu) |
| PH (1) | PH12020500034A1 (hu) |
| PL (2) | PL3645513T3 (hu) |
| PT (2) | PT4056557T (hu) |
| SA (1) | SA519410888B1 (hu) |
| SG (1) | SG11201912757VA (hu) |
| SI (1) | SI4056557T1 (hu) |
| TW (1) | TWI798234B (hu) |
| WO (2) | WO2019003433A1 (hu) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6868089B2 (ja) * | 2018-12-28 | 2021-05-12 | 大塚製薬株式会社 | 医薬 |
| CA3160645A1 (en) * | 2019-11-07 | 2021-05-14 | The Board Of Trustees Of The University Of Illinois | Inhibitors of influenza viral entry |
| CN111450879A (zh) * | 2020-05-08 | 2020-07-28 | 内蒙古自治区石油化工监督检验研究院 | 用于乙炔氢氯化反应的丙二胺改性低钌催化剂及制备方法 |
| CN116472271A (zh) * | 2020-11-26 | 2023-07-21 | 上海济煜医药科技有限公司 | 新型苯并氮杂卓螺环衍生物 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5985869A (en) * | 1989-10-20 | 1999-11-16 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
| JP2905909B2 (ja) | 1991-04-19 | 1999-06-14 | 大塚製薬株式会社 | バソプレシン拮抗剤 |
| US5258510A (en) * | 1989-10-20 | 1993-11-02 | Otsuka Pharma Co Ltd | Benzoheterocyclic compounds |
| EP0450097B1 (en) | 1989-10-20 | 1996-04-24 | Otsuka Pharmaceutical Co., Ltd. | Benzoheterocyclic compounds |
| WO1994001113A1 (en) | 1992-07-02 | 1994-01-20 | Otsuka Pharmaceutical Company, Limited | Oxytocin antagonist |
| JP2961291B2 (ja) * | 1992-08-20 | 1999-10-12 | 大塚製薬株式会社 | ベンゾヘテロ環化合物 |
| EP0612319A1 (en) | 1992-08-20 | 1994-08-31 | Otsuka Pharmaceutical Co., Ltd. | Benzoheterocyclic compounds as oxytocin and vasopressin antagonists |
| TW270927B (hu) | 1992-10-16 | 1996-02-21 | Otsuka Pharma Co Ltd | |
| JP2913082B2 (ja) * | 1992-10-16 | 1999-06-28 | 大塚製薬株式会社 | バソプレシン拮抗剤及びオキシトシン拮抗剤 |
| EP0716083A4 (en) | 1993-08-26 | 1996-08-28 | Yamanouchi Pharma Co Ltd | BENZAZEPINE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THEM, AND INTERMEDIATES THEREOF |
| DE69530690T2 (de) | 1994-06-15 | 2004-03-18 | Otsuka Pharmaceutical Co., Ltd. | Benzoheterocyclische derivate verwendbar als vasopressin- oder oxytocin-modulatoren |
| JPH09221476A (ja) | 1995-12-15 | 1997-08-26 | Otsuka Pharmaceut Co Ltd | 医薬組成物 |
| JPH10120592A (ja) | 1996-10-22 | 1998-05-12 | Otsuka Pharmaceut Co Ltd | メニエール病乃至メニエール症候群治療剤 |
| AUPP150098A0 (en) | 1998-01-27 | 1998-02-19 | Fujisawa Pharmaceutical Co., Ltd. | Benzamide derivatives |
| JP4374088B2 (ja) * | 1999-01-14 | 2009-12-02 | 東ソ−・エフテック株式会社 | 新規な４，４−ジフルオロベンゾアゼピンケタール誘導体、およびそれを経由する４，４−ジフルオロベンゾアゼピン−５−オン誘導体の製造方法 |
| EP1627876A1 (en) | 2004-08-20 | 2006-02-22 | Ferring B.V. | Heterocyclic condensed compounds useful as antidiuretic agents |
| TWI459947B (zh) * | 2007-06-26 | 2014-11-11 | Otsuka Pharma Co Ltd | 苯并氮呯化合物及藥學製劑 |
| WO2011052519A1 (ja) * | 2009-10-26 | 2011-05-05 | 大塚製薬株式会社 | ベンズアゼピン化合物 |
| US8025813B2 (en) | 2009-11-12 | 2011-09-27 | Rohm And Haas Electronic Materials Cmp Holdings, Inc. | Chemical mechanical polishing composition and methods relating thereto |
| JP2016513112A (ja) * | 2013-02-18 | 2016-05-12 | ザ スクリプス リサーチ インスティテュート | 治療的潜在能力を有するバソプレッシン受容体のモジュレーター |
| TW201605488A (zh) | 2013-10-15 | 2016-02-16 | 大塚製藥股份有限公司 | 用以預防及／或治療多囊腎病之藥物 |
-
2017
- 2017-06-30 WO PCT/JP2017/024211 patent/WO2019003433A1/ja active Application Filing
-
2018
- 2018-06-29 EP EP22164702.7A patent/EP4056557B1/en active Active
- 2018-06-29 DK DK22164702.7T patent/DK4056557T3/da active
- 2018-06-29 CA CA3068396A patent/CA3068396A1/en active Pending
- 2018-06-29 EP EP18743103.6A patent/EP3645513B1/en active Active
- 2018-06-29 DK DK18743103.6T patent/DK3645513T3/da active
- 2018-06-29 SI SI201831037T patent/SI4056557T1/sl unknown
- 2018-06-29 US US16/480,842 patent/US10889570B2/en active Active
- 2018-06-29 PL PL18743103.6T patent/PL3645513T3/pl unknown
- 2018-06-29 HR HRP20231616TT patent/HRP20231616T1/hr unknown
- 2018-06-29 TW TW107122567A patent/TWI798234B/zh active
- 2018-06-29 PL PL22164702.7T patent/PL4056557T3/pl unknown
- 2018-06-29 HR HRP20221359TT patent/HRP20221359T1/hr unknown
- 2018-06-29 CN CN201880041463.9A patent/CN110891939A/zh active Pending
- 2018-06-29 PT PT221647027T patent/PT4056557T/pt unknown
- 2018-06-29 KR KR1020207002409A patent/KR102632228B1/ko active IP Right Grant
- 2018-06-29 EA EA202090131A patent/EA202090131A1/ru unknown
- 2018-06-29 JP JP2019536110A patent/JP6688436B2/ja active Active
- 2018-06-29 ES ES22164702T patent/ES2964569T3/es active Active
- 2018-06-29 ES ES18743103T patent/ES2932854T3/es active Active
- 2018-06-29 LT LTEP22164702.7T patent/LT4056557T/lt unknown
- 2018-06-29 HU HUE18743103A patent/HUE060855T2/hu unknown
- 2018-06-29 SG SG11201912757VA patent/SG11201912757VA/en unknown
- 2018-06-29 WO PCT/JP2018/024786 patent/WO2019004421A1/en unknown
- 2018-06-29 LT LTEPPCT/JP2018/024786T patent/LT3645513T/lt unknown
- 2018-06-29 FI FIEP22164702.7T patent/FI4056557T3/fi active
- 2018-06-29 AU AU2018293081A patent/AU2018293081B2/en active Active
- 2018-06-29 HU HUE22164702A patent/HUE065010T2/hu unknown
- 2018-06-29 BR BR112019027678-5A patent/BR112019027678A2/pt active Search and Examination
- 2018-06-29 PT PT187431036T patent/PT3645513T/pt unknown
-
2019
- 2019-12-23 IL IL271665A patent/IL271665B2/en unknown
- 2019-12-24 SA SA519410888A patent/SA519410888B1/ar unknown
-
2020
- 2020-01-02 PH PH12020500034A patent/PH12020500034A1/en unknown
- 2020-04-03 JP JP2020067672A patent/JP7055160B2/ja active Active
- 2020-11-24 US US17/103,319 patent/US11673878B2/en active Active
-
2023
- 2023-04-27 US US18/140,348 patent/US20230265073A1/en active Pending
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