HUE058931T2 - Pilokarpin hidroklorid alkalmazása presbyopia kezelésére - Google Patents

Pilokarpin hidroklorid alkalmazása presbyopia kezelésére

Info

Publication number
HUE058931T2
HUE058931T2 HUE19729883A HUE19729883A HUE058931T2 HU E058931 T2 HUE058931 T2 HU E058931T2 HU E19729883 A HUE19729883 A HU E19729883A HU E19729883 A HUE19729883 A HU E19729883A HU E058931 T2 HUE058931 T2 HU E058931T2
Authority
HU
Hungary
Prior art keywords
presbyopia
treatment
pilocarpine hydrochloride
pilocarpine
hydrochloride
Prior art date
Application number
HUE19729883A
Other languages
English (en)
Hungarian (hu)
Inventor
Michael Robinson
Mohammed Dibas
Jaya Giyanani
Anuradha Gore
Sungwook Lee
Haixia Liu
Aileen Morgan
Jihao Zhou
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=66821312&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE058931(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of HUE058931T2 publication Critical patent/HUE058931T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HUE19729883A 2018-04-24 2019-04-24 Pilokarpin hidroklorid alkalmazása presbyopia kezelésére HUE058931T2 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862662144P 2018-04-24 2018-04-24
US201862780117P 2018-12-14 2018-12-14
US201962790957P 2019-01-10 2019-01-10

Publications (1)

Publication Number Publication Date
HUE058931T2 true HUE058931T2 (hu) 2022-09-28

Family

ID=66821312

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE19729883A HUE058931T2 (hu) 2018-04-24 2019-04-24 Pilokarpin hidroklorid alkalmazása presbyopia kezelésére

Country Status (25)

Country Link
US (4) US10610518B2 (cg-RX-API-DMAC7.html)
EP (2) EP3681500B2 (cg-RX-API-DMAC7.html)
JP (3) JP6946575B2 (cg-RX-API-DMAC7.html)
KR (2) KR20230079489A (cg-RX-API-DMAC7.html)
CN (1) CN112272558A (cg-RX-API-DMAC7.html)
AU (3) AU2019261598B9 (cg-RX-API-DMAC7.html)
BR (1) BR112020021845A2 (cg-RX-API-DMAC7.html)
CA (2) CA3074618C (cg-RX-API-DMAC7.html)
CL (1) CL2020002734A1 (cg-RX-API-DMAC7.html)
CO (1) CO2020014563A2 (cg-RX-API-DMAC7.html)
CY (1) CY1125325T1 (cg-RX-API-DMAC7.html)
DK (1) DK3681500T3 (cg-RX-API-DMAC7.html)
ES (1) ES2920803T5 (cg-RX-API-DMAC7.html)
HR (1) HRP20220762T1 (cg-RX-API-DMAC7.html)
HU (1) HUE058931T2 (cg-RX-API-DMAC7.html)
IL (1) IL278178A (cg-RX-API-DMAC7.html)
LT (1) LT3681500T (cg-RX-API-DMAC7.html)
MX (1) MX2020011301A (cg-RX-API-DMAC7.html)
PH (1) PH12020551766A1 (cg-RX-API-DMAC7.html)
PL (1) PL3681500T3 (cg-RX-API-DMAC7.html)
PT (1) PT3681500T (cg-RX-API-DMAC7.html)
RS (1) RS63360B1 (cg-RX-API-DMAC7.html)
SG (1) SG11202010472XA (cg-RX-API-DMAC7.html)
SI (1) SI3681500T1 (cg-RX-API-DMAC7.html)
WO (1) WO2019209955A2 (cg-RX-API-DMAC7.html)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7274475B2 (ja) 2017-07-20 2023-05-16 セインダ ファーマシューティカル グアンジョウ コーポレイション 近視の処置のための組成物および方法
US20210251970A1 (en) 2018-10-10 2021-08-19 Presbyopia Therapies Inc Compositions and methods for storage stable ophthalmic drugs
US12161629B2 (en) 2018-10-15 2024-12-10 Opus Genetics, Inc. Methods and compositions for treatment of glaucoma and related conditions
CN113164452A (zh) 2018-10-26 2021-07-23 奥库菲尔制药股份有限公司 治疗老花眼、散瞳和其他眼部疾病的方法和组合物
EP4210690B1 (en) * 2020-09-11 2025-01-29 Intratus-Nevada, Inc. Compositions and methods for treating presbyopia, hyperopia, astigmatism, decreased stereopsis, and decreased contrast sensitivity
CA3210064A1 (en) * 2021-01-28 2022-08-04 Glaukos Corporation Formulations
WO2022232205A1 (en) * 2021-04-28 2022-11-03 Lenz Therapeutics, Inc. A method of reducing brow ache
CN115368310B (zh) 2021-05-18 2025-06-27 奥库菲尔医药公司 合成甲磺酸酚妥拉明的方法
US12180206B2 (en) 2021-11-17 2024-12-31 Lenz Therapeutics Operations, Inc. Aceclidine derivatives, compositions thereof and methods of use thereof
WO2023125544A1 (zh) 2021-12-28 2023-07-06 沈阳兴齐眼药股份有限公司 组合物及其在制备用于治疗老花眼的药物中的用途
US11857538B2 (en) 2022-01-14 2024-01-02 Somerset Therapeutics, Llc Stable pilocarpine formulations with modified buffer characteristics and related methods
US11969410B2 (en) 2022-02-09 2024-04-30 Somerset Therapeutics, Llc Low pH pilocarpine and brimonidine compound formulations and related methods
CN119584954A (zh) 2022-04-21 2025-03-07 格劳科斯公司 眼用局部乳膏组合物
US20230372303A1 (en) 2022-05-18 2023-11-23 Glaukos Corporation Applications of zwitterions in ophthalmic topical cream compositions and preparations
CN117243888A (zh) * 2023-09-22 2023-12-19 南京海纳制药有限公司 一种含有盐酸毛果芸香碱滴眼水性药物组合物及其制备方法
US12414942B1 (en) 2024-03-15 2025-09-16 Lenz Therapeutics Operations, Inc. Compositions, methods, and systems for treating presbyopia

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474751A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4851521A (en) 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
CA2003198C (en) 1988-11-29 1995-03-21 Anthony J. Dziabo, Jr. Aqueous ophthalmic solutions and method for preserving same
US5122522A (en) 1989-06-21 1992-06-16 The Trustees Of The University Of Pennsylvania Treatment and control of ocular development
US5055467A (en) 1989-11-13 1991-10-08 Allergan, Inc. Pharmaceutical epinephrine-pilocarpine compounds
US5496471A (en) 1990-01-08 1996-03-05 Ciba-Geigy Corporation Apparatus for removing components from solutions
US5776916A (en) 1990-07-10 1998-07-07 Gramer; Eugen Medicament for reducing the intraocular pressure
CA2064160C (en) 1991-03-27 1998-08-11 Paul J. T. Missel Use of combinations of gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
US5459133A (en) 1992-06-05 1995-10-17 Telor Ophthalmic Pharmaceuticals, Inc. Methods and products for treating presbyopia
JPH07508751A (ja) 1992-07-02 1995-09-28 テラー・オフサルミック・ファーマシューティカルズ・インコーポレーテッド 老視治療のための方法および生産品
SE512871C2 (sv) 1992-08-20 2000-05-29 Santen Oy Oftalmologisk beredning innehållande pilokarpin och ytterligare medel för behandling av okular hypertension
AU5599594A (en) * 1992-11-16 1994-06-08 Ciba-Geigy Ag Polyvinyl alcohol/borate ophthalmic drug delivery system
US5422116A (en) 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
SE9401109D0 (sv) * 1994-03-31 1994-03-31 Leiras Oy Opthalmic composition II
US5574518A (en) 1995-01-10 1996-11-12 Les Laboratoires Opti-Centre Inc. System incorporation two different sphero-non-spherical contact lenses for correcting presbytia
US5612027A (en) 1995-04-18 1997-03-18 Galin; Miles A. Controlled release of miotic and mydriatic drugs in the anterior chamber
US6291466B1 (en) * 1998-07-30 2001-09-18 Allergan Sales, Inc. Cholinergic agents in the treatment of presbyopia
US6164282A (en) 1999-01-27 2000-12-26 Allergan Sales, Inc. Methods for restoring and/or enhancing accommodation in pseudo phakia
CH693625A5 (it) 1999-02-18 2003-11-28 Inpharma Sa Composizioni farmaceutiche contenenti composti ad attività promotrice di assorbimento di principi attivi.
IT1306135B1 (it) 1999-04-26 2001-05-30 Farmigea Spa Composizioni oftalmiche per il trattamento delle turbe visivecaratterizzate da ridotta sensibilita' al contrasto.
AU7581000A (en) 1999-09-16 2001-04-17 Gerald D. Horn A method for optimizing pupil size using alpha antagonist
US6420407B1 (en) 1999-09-16 2002-07-16 Gerald Horn Ophthalmic formulation which modulates dilation
TWI227143B (en) 1999-12-15 2005-02-01 Guo-Jiun Sung In situ gel formation for ophthalmic delivery by combining Pluronic/Carbopol medic composition and its preparing method
US6218428B1 (en) 2000-04-28 2001-04-17 Emil Chynn Ophthalmic composition
PE20020146A1 (es) 2000-07-13 2002-03-31 Upjohn Co Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
WO2002024116A1 (en) 2000-09-20 2002-03-28 Shahinian, Lee, Jr. Self-preserved nasal, inhalable, and topical ophthalmic preparations and medications
US6273092B1 (en) 2000-09-22 2001-08-14 Gerard M. Nolan Methods for treating various eye disorders
ITMI20010708A1 (it) 2001-04-03 2002-10-03 Alessandro Randazzo Trattamento farmacologico degli aloni notturni e delle immagini fantasma con parasimpaticomimetici diluiti aceclidina/pilocarpina dopo inter
US20030139737A1 (en) 2002-01-24 2003-07-24 J.T. Lin Method and apparatus for treatment of presbyopia by lens relaxation and anterior shift
CA2493581C (en) 2002-07-30 2014-12-23 Omeros Corporation Ophthalmologic irrigation solutions and method
US20070211212A1 (en) 2002-09-26 2007-09-13 Percy Bennwik Eye state sensor
US20050261641A1 (en) 2002-09-26 2005-11-24 Warchol Mark P Method for ophthalmic administration of medicament
US20040078009A1 (en) 2002-10-17 2004-04-22 Lin J. T. Method and apparatus for the treatment of presbyopia and other eye disorders combining pharmocological and surgical means
US20050205101A1 (en) * 2002-10-17 2005-09-22 Lin J T Combined pharmocological and surgical method and system for the treatment of eye disorders
US20060177430A1 (en) 2002-12-20 2006-08-10 Chakshu Research Inc Treatment of ocular disorders with ophthalmic formulations containing methylsulfonylmethane as a transport enhancer
EP1592435A4 (en) 2002-12-20 2008-01-23 Chakshu Res Inc EYE FORMULATION FOR THE PREVENTION AND TREATMENT OF EYE DRESS
EP2163643B1 (en) 2003-03-05 2015-01-21 Halozyme, Inc. Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
US20050119262A1 (en) 2003-08-21 2005-06-02 Pharmacia Corporation Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
PL1754491T3 (pl) 2004-05-21 2010-08-31 Senju Pharma Co Preparat do oczu do wchłaniania przezskórnego zawierający agonistę receptora muskarynowego
US20050279369A1 (en) 2004-06-21 2005-12-22 Lin J T Method and apparatus for the treatment of presbyopia and glaucoma by ciliary body ablation
CA2614519A1 (en) 2004-10-22 2006-05-04 Omer Yilmaz System and method for aligning an optic with an axis of an eye
BRPI0615432A2 (pt) 2005-09-02 2011-05-17 Theravida Inc composição farmacêutica, e, uso de compostos
US8158152B2 (en) 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
DK2038252T3 (en) 2006-07-12 2016-12-19 Univ Tennessee Res Found SUBSTITUTED AND ACYLANILIDER methods of use thereof
ATE439863T1 (de) 2006-12-18 2009-09-15 Jorge Luis Benozzi Ophthalmische zusammensetzungen von parasympathischen stimulantia und entzündungshemmer zur verwendung bei der behandlung von presbyopie
WO2009046967A1 (en) 2007-10-08 2009-04-16 Fovea Pharmaceuticals Sa Aqueous ophthalmic formulations
AU2015202175A1 (en) 2007-12-15 2015-05-14 Anant Sharma Optical correction
GB0724558D0 (en) 2007-12-15 2008-01-30 Sharma Anant Optical correction
WO2010125416A1 (en) 2009-04-27 2010-11-04 Raouf Rekik Drug delivery to the anterior and posterior segments of the eye
WO2010135731A1 (en) 2009-05-22 2010-11-25 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
US8299079B2 (en) 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
TW201109325A (en) 2009-07-30 2011-03-16 Wakamoto Pharma Co Ltd Aqueous composition for eye drops
AR081049A1 (es) 2010-08-17 2012-06-06 Gonzalez Santos Alejandro Raul Medicamento oftalmico para el tratamiento de la hipermetropia
US9119772B2 (en) * 2011-01-26 2015-09-01 Allergan, Inc. Androgen composition for treating an opthalmic condition
UA113525C2 (xx) 2011-09-20 2017-02-10 Спосіб лікування пресбіопії
AU2012322917B2 (en) 2011-10-12 2016-11-03 Ascendis Pharma Ophthalmology Division A/S Prevention and treatment of ocular conditions
US20130157963A1 (en) 2011-12-16 2013-06-20 Allergan, Inc. Ophthalmic compositions comprising polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymers
EP2630952A1 (en) 2012-02-23 2013-08-28 Novagali Pharma S.A. Self-preserved oil dispersions comprising boric acid
US10507245B2 (en) 2012-07-19 2019-12-17 Luis Felipe Vejarano Restrepo Ophthalmic formulation and method for ameliorating presbyopia
EP2950800B1 (en) 2013-02-01 2020-09-09 Ocuphire Pharma, Inc. Methods and compositions for daily ophthalmic administration of phentolamine to improve visual performance
US9795560B2 (en) 2013-02-01 2017-10-24 Ocularis Pharma, Llc Aqueous ophthalmic solutions of phentolamine and medical uses thereof
US9089562B2 (en) 2013-08-28 2015-07-28 Presbyopia Therapies Llc Compositions and methods for the treatment of presbyopia
US9968594B2 (en) 2013-08-28 2018-05-15 Presbyopia Therapies Llc Compositions and methods for the treatment of presbyopia
US9314427B2 (en) 2013-08-28 2016-04-19 Presbyopia Therapies Llc Compositions and methods for the improvement of distance vision and the treatment of refractive errors of the eye
US8859623B1 (en) 2013-11-14 2014-10-14 Paragon BioTeck, Inc. Methods and compositions of stable phenylephrine formulations
ES2538551B1 (es) 2013-12-20 2016-01-13 Eurocanarias Oftalmológica, Sl Composición Oftálmica para la corrección de la presbicia
EP3750541A1 (en) 2014-01-10 2020-12-16 Santen Pharmaceutical Co., Ltd Pharmaceutical preparation containing pyridylaminoacetic acid compound
AU2014382677A1 (en) 2014-02-11 2016-09-01 Orasis Pharmaceuticals Ltd. Pharmacological ophthalmic composition for use in the correction of presbyopia and its administration
US11052094B2 (en) 2015-05-29 2021-07-06 Sydnexis, Inc. D2O stabilized pharmaceutical formulations
US20190000808A1 (en) 2015-07-13 2019-01-03 Allergan, Inc. Composition and methods for the treatment of blephopharoptosis
CH711969A2 (it) 2015-12-29 2017-06-30 Pinelli Roberto Composizione per il trattamento della presbiopia.
US10231968B2 (en) 2016-08-01 2019-03-19 David R. Hardten Medicinal solution to be continuously or pulse-delivered to the eye for treating ophthalmological conditions/maladies
WO2018033792A2 (en) 2016-08-19 2018-02-22 Orasis Pharmaceuticals Ltd. Ophthalmic pharmaceutical compositions and uses relating thereto
EP3525885B1 (en) 2016-10-12 2022-01-26 PS Therapy Ltd. Artificial tear, contact lens and drug vehicle compositions and methods of use thereof

Also Published As

Publication number Publication date
US20190321337A1 (en) 2019-10-24
JP2022008403A (ja) 2022-01-13
ES2920803T3 (es) 2022-08-09
AU2019261598B2 (en) 2020-05-14
US20220241245A1 (en) 2022-08-04
JP6946575B2 (ja) 2021-10-06
JP2024096131A (ja) 2024-07-12
RS63360B1 (sr) 2022-07-29
CA3074618C (en) 2022-08-02
CN112272558A (zh) 2021-01-26
AU2020203311A1 (en) 2020-06-11
EP4066830A1 (en) 2022-10-05
EP3681500B1 (en) 2022-03-23
ES2920803T5 (en) 2025-11-11
JP7470667B2 (ja) 2024-04-18
PL3681500T3 (pl) 2022-08-01
SG11202010472XA (en) 2020-11-27
HRP20220762T1 (hr) 2022-09-16
SI3681500T1 (sl) 2022-09-30
US20240382462A1 (en) 2024-11-21
WO2019209955A3 (en) 2020-01-23
US20210008034A1 (en) 2021-01-14
EP3681500B2 (en) 2025-07-30
MX2020011301A (es) 2021-01-29
BR112020021845A2 (pt) 2021-02-23
AU2019261598A1 (en) 2020-03-19
CA3074618A1 (en) 2019-10-31
EP3681500A2 (en) 2020-07-22
WO2019209955A2 (en) 2019-10-31
CA3162141A1 (en) 2019-10-31
US11285134B2 (en) 2022-03-29
IL278178A (en) 2020-11-30
LT3681500T (lt) 2022-06-27
DK3681500T3 (da) 2022-06-27
KR20210005134A (ko) 2021-01-13
PH12020551766A1 (en) 2021-07-12
CO2020014563A2 (es) 2021-02-26
CL2020002734A1 (es) 2021-03-12
AU2019261598B9 (en) 2020-05-28
JP2021522256A (ja) 2021-08-30
US10610518B2 (en) 2020-04-07
KR20230079489A (ko) 2023-06-07
AU2022201106A1 (en) 2022-03-10
PT3681500T (pt) 2022-06-27
CY1125325T1 (el) 2025-03-28

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