HUE055764T2 - Új pikolinsav származékok és alkalmazásuk intermedierekként - Google Patents
Új pikolinsav származékok és alkalmazásuk intermedierekkéntInfo
- Publication number
- HUE055764T2 HUE055764T2 HUE17826574A HUE17826574A HUE055764T2 HU E055764 T2 HUE055764 T2 HU E055764T2 HU E17826574 A HUE17826574 A HU E17826574A HU E17826574 A HUE17826574 A HU E17826574A HU E055764 T2 HUE055764 T2 HU E055764T2
- Authority
- HU
- Hungary
- Prior art keywords
- intermediates
- acid derivatives
- picolinic acid
- new
- new picolinic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662436222P | 2016-12-19 | 2016-12-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE055764T2 true HUE055764T2 (hu) | 2021-12-28 |
Family
ID=60953912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE17826574A HUE055764T2 (hu) | 2016-12-19 | 2017-12-18 | Új pikolinsav származékok és alkalmazásuk intermedierekként |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10633341B2 (hu) |
| EP (1) | EP3555048B1 (hu) |
| JP (1) | JP7063902B2 (hu) |
| KR (1) | KR102454635B1 (hu) |
| CN (1) | CN110072851B (hu) |
| AU (1) | AU2017381739B2 (hu) |
| CA (1) | CA3044366A1 (hu) |
| DK (1) | DK3555048T3 (hu) |
| ES (1) | ES2891527T3 (hu) |
| HU (1) | HUE055764T2 (hu) |
| IL (1) | IL267042B (hu) |
| PL (1) | PL3555048T3 (hu) |
| PT (1) | PT3555048T (hu) |
| RU (1) | RU2769693C2 (hu) |
| SI (1) | SI3555048T1 (hu) |
| WO (1) | WO2018116139A1 (hu) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11865109B2 (en) | 2019-07-15 | 2024-01-09 | Novartis Ag | Formulations of (S)-3-amino-6-methoxy-N-(3,3,3-trifluoro-2-hydroxy-2-methylpropyl)-5-(trifluoromethyl)picolinamide |
| WO2023109939A1 (zh) * | 2021-12-17 | 2023-06-22 | 苏州晶云药物科技股份有限公司 | 吡啶类衍生物的晶型及其制备方法 |
| CN115073366A (zh) * | 2022-06-08 | 2022-09-20 | 都创(重庆)医药科技有限公司 | 一种基于微通道技术快速制备3-氯吡啶-2-甲酸的方法 |
| CN116396213B (zh) * | 2023-04-14 | 2024-06-14 | 济南大学 | 一种2-吡啶甲酸甲酯的制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0929524A1 (de) | 1996-09-18 | 1999-07-21 | Basf Aktiengesellschaft | Pyridinderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von tierischen schädlingen und schadpilzen |
| BR9713027A (pt) | 1996-11-12 | 2000-01-25 | Novartis Ag | Derivados de pirazol úteis como herbicidas |
| EP1582524B1 (en) | 2004-04-02 | 2008-08-13 | Ludwig Maximilians Universität | Method of preparing organomagnesium compounds |
| EP1810974A1 (en) | 2006-01-18 | 2007-07-25 | Ludwig-Maximilians-Universität München | Preparation and use of magnesium amides |
| KR101390076B1 (ko) * | 2006-11-08 | 2014-04-29 | 브리스톨-마이어스 스큅 컴퍼니 | 피리디논 화합물 |
| WO2008119015A2 (en) | 2007-03-27 | 2008-10-02 | Sloan-Kettering Institute For Cancer Research | Synthesis of thiohydantoins |
| DE102007022490A1 (de) | 2007-05-14 | 2008-11-20 | Ludwig-Maximilians-Universität | Bisamid-Zinkbasen |
| US8247436B2 (en) | 2010-03-19 | 2012-08-21 | Novartis Ag | Pyridine and pyrazine derivative for the treatment of CF |
| ES2516165T3 (es) * | 2010-07-12 | 2014-10-30 | F. Hoffmann-La Roche Ag | 1-hidroxiimino-3-fenil-propanos |
| WO2013038373A1 (en) | 2011-09-16 | 2013-03-21 | Novartis Ag | Pyridine amide derivatives |
| WO2013038378A1 (en) | 2011-09-16 | 2013-03-21 | Novartis Ag | Pyridine amide derivatives |
| ES2558457T3 (es) | 2011-09-16 | 2016-02-04 | Novartis Ag | Compuestos heterocíclicos para el tratamiento de fibrosis quística |
| WO2013057711A1 (en) | 2011-10-21 | 2013-04-25 | Novartis Ag | Quinazoline derivatives as pi3k modulators |
| MX370140B (es) | 2014-06-06 | 2019-12-03 | Astellas Pharma Inc | Derivado de 2-acilaminotiazol o sal del mismo. |
| CN108368084B (zh) | 2015-10-01 | 2020-10-16 | 百时美施贵宝公司 | 联芳基激酶抑制剂 |
| MA44489A (fr) | 2016-03-25 | 2019-01-30 | Afferent Pharmaceuticals Inc | Pyrimidines et variants de celles-ci, et leurs utilisations |
-
2017
- 2017-12-18 DK DK17826574.0T patent/DK3555048T3/da active
- 2017-12-18 US US16/470,778 patent/US10633341B2/en active Active
- 2017-12-18 RU RU2019122609A patent/RU2769693C2/ru active
- 2017-12-18 SI SI201730932T patent/SI3555048T1/sl unknown
- 2017-12-18 KR KR1020197017408A patent/KR102454635B1/ko active IP Right Grant
- 2017-12-18 PL PL17826574T patent/PL3555048T3/pl unknown
- 2017-12-18 CA CA3044366A patent/CA3044366A1/en active Pending
- 2017-12-18 CN CN201780076811.1A patent/CN110072851B/zh active Active
- 2017-12-18 AU AU2017381739A patent/AU2017381739B2/en active Active
- 2017-12-18 ES ES17826574T patent/ES2891527T3/es active Active
- 2017-12-18 HU HUE17826574A patent/HUE055764T2/hu unknown
- 2017-12-18 EP EP17826574.0A patent/EP3555048B1/en active Active
- 2017-12-18 WO PCT/IB2017/058081 patent/WO2018116139A1/en unknown
- 2017-12-18 PT PT178265740T patent/PT3555048T/pt unknown
- 2017-12-18 JP JP2019533109A patent/JP7063902B2/ja active Active
-
2019
- 2019-06-02 IL IL267042A patent/IL267042B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP7063902B2 (ja) | 2022-05-09 |
| IL267042A (en) | 2019-07-31 |
| JP2020502194A (ja) | 2020-01-23 |
| PL3555048T3 (pl) | 2021-12-06 |
| KR20190091460A (ko) | 2019-08-06 |
| US10633341B2 (en) | 2020-04-28 |
| EP3555048A1 (en) | 2019-10-23 |
| US20190345107A1 (en) | 2019-11-14 |
| IL267042B (en) | 2021-12-01 |
| AU2017381739A1 (en) | 2019-05-30 |
| ES2891527T3 (es) | 2022-01-28 |
| KR102454635B1 (ko) | 2022-10-17 |
| SI3555048T1 (sl) | 2021-11-30 |
| WO2018116139A1 (en) | 2018-06-28 |
| RU2019122609A3 (hu) | 2021-02-19 |
| RU2769693C2 (ru) | 2022-04-05 |
| CN110072851B (zh) | 2023-06-06 |
| DK3555048T3 (da) | 2021-10-11 |
| CN110072851A (zh) | 2019-07-30 |
| PT3555048T (pt) | 2021-09-29 |
| CA3044366A1 (en) | 2018-06-28 |
| EP3555048B1 (en) | 2021-07-07 |
| AU2017381739B2 (en) | 2020-06-11 |
| RU2019122609A (ru) | 2021-01-19 |
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