PL3555048T3 - Nowe pochodne kwasu pikolinowego i ich zastosowanie jako związki pośrednie - Google Patents
Nowe pochodne kwasu pikolinowego i ich zastosowanie jako związki pośrednieInfo
- Publication number
- PL3555048T3 PL3555048T3 PL17826574T PL17826574T PL3555048T3 PL 3555048 T3 PL3555048 T3 PL 3555048T3 PL 17826574 T PL17826574 T PL 17826574T PL 17826574 T PL17826574 T PL 17826574T PL 3555048 T3 PL3555048 T3 PL 3555048T3
- Authority
- PL
- Poland
- Prior art keywords
- intermediates
- acid derivatives
- picolinic acid
- new
- new picolinic
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title 1
- SIOXPEMLGUPBBT-UHFFFAOYSA-N picolinic acid Chemical class OC(=O)C1=CC=CC=N1 SIOXPEMLGUPBBT-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662436222P | 2016-12-19 | 2016-12-19 | |
| PCT/IB2017/058081 WO2018116139A1 (en) | 2016-12-19 | 2017-12-18 | New picolinic acid derivatives and their use as intermediates |
| EP17826574.0A EP3555048B1 (en) | 2016-12-19 | 2017-12-18 | New picolinic acid derivatives and their use as intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3555048T3 true PL3555048T3 (pl) | 2021-12-06 |
Family
ID=60953912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17826574T PL3555048T3 (pl) | 2016-12-19 | 2017-12-18 | Nowe pochodne kwasu pikolinowego i ich zastosowanie jako związki pośrednie |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10633341B2 (pl) |
| EP (1) | EP3555048B1 (pl) |
| JP (1) | JP7063902B2 (pl) |
| KR (1) | KR102454635B1 (pl) |
| CN (1) | CN110072851B (pl) |
| AU (1) | AU2017381739B2 (pl) |
| CA (1) | CA3044366A1 (pl) |
| DK (1) | DK3555048T3 (pl) |
| ES (1) | ES2891527T3 (pl) |
| HU (1) | HUE055764T2 (pl) |
| IL (1) | IL267042B (pl) |
| PL (1) | PL3555048T3 (pl) |
| PT (1) | PT3555048T (pl) |
| RU (1) | RU2769693C2 (pl) |
| SI (1) | SI3555048T1 (pl) |
| WO (1) | WO2018116139A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202116312A (zh) * | 2019-07-15 | 2021-05-01 | 瑞士商諾華公司 | （ｓ）—３—胺基—６—甲氧基—ｎ—（３，３，３—三氟—２—羥基—２—甲基丙基）—５—（三氟甲基）吡啶甲醯胺配製物 |
| WO2023109939A1 (zh) * | 2021-12-17 | 2023-06-22 | 苏州晶云药物科技股份有限公司 | 吡啶类衍生物的晶型及其制备方法 |
| CN115073366B (zh) * | 2022-06-08 | 2024-08-09 | 都创(重庆)医药科技有限公司 | 一种基于微通道技术快速制备3-氯吡啶-2-甲酸的方法 |
| CN116396213B (zh) * | 2023-04-14 | 2024-06-14 | 济南大学 | 一种2-吡啶甲酸甲酯的制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001500516A (ja) | 1996-09-18 | 2001-01-16 | ビーエーエスエフ アクチェンゲゼルシャフト | ピリジン誘導体、その製造、及び有害菌類及び有害動物の防除へのその使用方法 |
| BR9713027A (pt) | 1996-11-12 | 2000-01-25 | Novartis Ag | Derivados de pirazol úteis como herbicidas |
| EP1582524B1 (en) | 2004-04-02 | 2008-08-13 | Ludwig Maximilians Universität | Method of preparing organomagnesium compounds |
| EP1810974A1 (en) | 2006-01-18 | 2007-07-25 | Ludwig-Maximilians-Universität München | Preparation and use of magnesium amides |
| CN101535264B (zh) * | 2006-11-08 | 2012-11-28 | 百时美施贵宝公司 | 吡啶酮化合物 |
| US8461343B2 (en) | 2007-03-27 | 2013-06-11 | Sloan-Kettering Institute For Cancer Research | Synthesis of thiohydantoins |
| DE102007022490A1 (de) | 2007-05-14 | 2008-11-20 | Ludwig-Maximilians-Universität | Bisamid-Zinkbasen |
| US8247436B2 (en) | 2010-03-19 | 2012-08-21 | Novartis Ag | Pyridine and pyrazine derivative for the treatment of CF |
| MX2013000391A (es) * | 2010-07-12 | 2013-03-08 | Hoffmann La Roche | 1-hidroxiimino-3-fenil-propanos. |
| WO2013038373A1 (en) | 2011-09-16 | 2013-03-21 | Novartis Ag | Pyridine amide derivatives |
| WO2013038378A1 (en) | 2011-09-16 | 2013-03-21 | Novartis Ag | Pyridine amide derivatives |
| ES2558457T3 (es) | 2011-09-16 | 2016-02-04 | Novartis Ag | Compuestos heterocíclicos para el tratamiento de fibrosis quística |
| WO2013057711A1 (en) * | 2011-10-21 | 2013-04-25 | Novartis Ag | Quinazoline derivatives as pi3k modulators |
| ES2732066T3 (es) | 2014-06-06 | 2019-11-20 | Astellas Pharma Inc | Derivado de 2-acilaminotiazol para su uso en la prevención o el tratamiento de enfermedades de la vejiga/vías urinarias |
| ES2765730T3 (es) | 2015-10-01 | 2020-06-10 | Bristol Myers Squibb Co | Inhibidores de biaril cinasa |
| US10662162B2 (en) | 2016-03-25 | 2020-05-26 | Afferent Pharmaceuticals, Inc. | Pyrimidines and variants thereof, and uses therefor |
-
2017
- 2017-12-18 PL PL17826574T patent/PL3555048T3/pl unknown
- 2017-12-18 EP EP17826574.0A patent/EP3555048B1/en active Active
- 2017-12-18 SI SI201730932T patent/SI3555048T1/sl unknown
- 2017-12-18 AU AU2017381739A patent/AU2017381739B2/en not_active Ceased
- 2017-12-18 CA CA3044366A patent/CA3044366A1/en active Pending
- 2017-12-18 WO PCT/IB2017/058081 patent/WO2018116139A1/en not_active Ceased
- 2017-12-18 US US16/470,778 patent/US10633341B2/en active Active
- 2017-12-18 KR KR1020197017408A patent/KR102454635B1/ko active Active
- 2017-12-18 ES ES17826574T patent/ES2891527T3/es active Active
- 2017-12-18 PT PT178265740T patent/PT3555048T/pt unknown
- 2017-12-18 RU RU2019122609A patent/RU2769693C2/ru active
- 2017-12-18 CN CN201780076811.1A patent/CN110072851B/zh not_active Expired - Fee Related
- 2017-12-18 DK DK17826574.0T patent/DK3555048T3/da active
- 2017-12-18 HU HUE17826574A patent/HUE055764T2/hu unknown
- 2017-12-18 JP JP2019533109A patent/JP7063902B2/ja not_active Expired - Fee Related
-
2019
- 2019-06-02 IL IL267042A patent/IL267042B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3555048B1 (en) | 2021-07-07 |
| RU2019122609A3 (pl) | 2021-02-19 |
| RU2019122609A (ru) | 2021-01-19 |
| CA3044366A1 (en) | 2018-06-28 |
| PT3555048T (pt) | 2021-09-29 |
| IL267042A (en) | 2019-07-31 |
| IL267042B (en) | 2021-12-01 |
| US10633341B2 (en) | 2020-04-28 |
| ES2891527T3 (es) | 2022-01-28 |
| EP3555048A1 (en) | 2019-10-23 |
| HUE055764T2 (hu) | 2021-12-28 |
| CN110072851A (zh) | 2019-07-30 |
| RU2769693C2 (ru) | 2022-04-05 |
| JP7063902B2 (ja) | 2022-05-09 |
| SI3555048T1 (sl) | 2021-11-30 |
| US20190345107A1 (en) | 2019-11-14 |
| JP2020502194A (ja) | 2020-01-23 |
| KR20190091460A (ko) | 2019-08-06 |
| WO2018116139A1 (en) | 2018-06-28 |
| AU2017381739B2 (en) | 2020-06-11 |
| AU2017381739A1 (en) | 2019-05-30 |
| KR102454635B1 (ko) | 2022-10-17 |
| CN110072851B (zh) | 2023-06-06 |
| DK3555048T3 (da) | 2021-10-11 |
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