HUE049027T2 - Diazabiciklooktán-származékok és intermedierek elõállítási eljárása - Google Patents
Diazabiciklooktán-származékok és intermedierek elõállítási eljárásaInfo
- Publication number
- HUE049027T2 HUE049027T2 HUE14847854A HUE14847854A HUE049027T2 HU E049027 T2 HUE049027 T2 HU E049027T2 HU E14847854 A HUE14847854 A HU E14847854A HU E14847854 A HUE14847854 A HU E14847854A HU E049027 T2 HUE049027 T2 HU E049027T2
- Authority
- HU
- Hungary
- Prior art keywords
- intermediates
- preparation
- diazabicyclooctane derivatives
- diazabicyclooctane
- derivatives
- Prior art date
Links
- NFDXQGNDWIPXQL-UHFFFAOYSA-N 1-cyclooctyldiazocane Chemical class C1CCCCCCC1N1NCCCCCC1 NFDXQGNDWIPXQL-UHFFFAOYSA-N 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013197110 | 2013-09-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE049027T2 true HUE049027T2 (hu) | 2020-08-28 |
Family
ID=52743343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE14847854A HUE049027T2 (hu) | 2013-09-24 | 2014-09-24 | Diazabiciklooktán-származékok és intermedierek elõállítási eljárása |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US10000491B2 (https=) |
| EP (1) | EP3050883B1 (https=) |
| JP (1) | JP6453222B2 (https=) |
| KR (1) | KR102239725B1 (https=) |
| CN (2) | CN105555787B (https=) |
| AR (5) | AR097744A1 (https=) |
| AU (1) | AU2014324302B2 (https=) |
| BR (1) | BR112016006246B8 (https=) |
| CA (1) | CA2924953C (https=) |
| DK (1) | DK3050883T3 (https=) |
| ES (1) | ES2793201T3 (https=) |
| HK (1) | HK1244487A1 (https=) |
| HU (1) | HUE049027T2 (https=) |
| IL (1) | IL244740B (https=) |
| MX (2) | MX367578B (https=) |
| MY (2) | MY176278A (https=) |
| NZ (1) | NZ718009A (https=) |
| RU (1) | RU2719480C2 (https=) |
| SG (1) | SG11201602256UA (https=) |
| TW (1) | TWI644908B (https=) |
| WO (1) | WO2015046207A1 (https=) |
| ZA (1) | ZA201602053B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE046893T2 (hu) | 2012-05-30 | 2020-04-28 | Meiji Seika Pharma Co Ltd | Új ß-laktamáz inhibitor és eljárás elõállítására |
| JP6453222B2 (ja) | 2013-09-24 | 2019-01-16 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | ジアザビシクロオクタン誘導体の製造法とその中間体 |
| ES2901198T3 (es) | 2013-10-08 | 2022-03-21 | Meiji Seika Pharma Co Ltd | Formas cristalinas de derivado de diazabiciclooctano y procedimiento de producción de las mismas |
| MY190283A (en) | 2014-12-05 | 2022-04-12 | Meiji Seika Pharma Co Ltd | Method for producing crystals of diazabicyclooctane derivative and stable lyophilized preparation |
| CA2944306C (en) | 2015-10-30 | 2023-11-14 | The Toronto-Dominion Bank | Validating encrypted data from a multi-layer token |
| US11216808B2 (en) | 2015-11-04 | 2022-01-04 | The Toronto-Dominion Bank | Token-based system for excising data from databases |
| JP2020011901A (ja) * | 2016-10-20 | 2020-01-23 | 協和キリン株式会社 | ピロリジン化合物の製造方法 |
| CN106699756B (zh) * | 2016-12-30 | 2019-10-29 | 淄博鑫泉医药技术服务有限公司 | β内酰胺酶抑制剂阿维巴坦的合成方法 |
| KR20200091395A (ko) | 2017-09-27 | 2020-07-30 | 페도라 파마슈티칼스 인코포레이티드 | 디아자비시클로옥탄 유도체의 결정형 및 그의 제조 방법 |
| US10584123B2 (en) | 2017-09-27 | 2020-03-10 | Fedora Pharmaceuticals Inc. | Pharmaceutical forms of diazabicyclooctane derivatives and manufacturing method thereof |
| US10682413B2 (en) | 2017-09-27 | 2020-06-16 | Fedora Pharmaceuticals Inc. | Pharmaceutical forms of diazabicyclooctane derivatives and process for producing the same |
| CN109678856B (zh) * | 2017-10-18 | 2020-09-25 | 新发药业有限公司 | 一种阿维巴坦中间体的制备方法 |
| JP7289836B2 (ja) | 2017-11-23 | 2023-06-12 | エフ． ホフマン－ラ ロシュ アーゲー | プロリンヒドロキシラーゼ、ならびにそれに伴う使用、方法および生成物 |
| WO2020018462A1 (en) | 2018-07-16 | 2020-01-23 | Brown University | A chromogenic beta-lactamase substrate |
| EP3854786B1 (en) * | 2018-09-21 | 2026-02-18 | UBE Corporation | Method for producing amino acid derivatives |
| US12195755B2 (en) | 2019-05-20 | 2025-01-14 | Brown University | Placental lipid bilayer for cell-free molecular interaction studies |
| WO2021038403A1 (en) | 2019-08-30 | 2021-03-04 | DePuy Synthes Products, Inc. | Electrical device for monitoring, prevention, and treatment of implant infections |
| US12509559B2 (en) | 2019-10-28 | 2025-12-30 | Brown University | Bacterial beta-lactamase responsive hydrogels |
| CN121021508B (zh) * | 2025-10-29 | 2026-02-24 | 北京耀诚惠仁科技有限公司 | β-内酰胺酶抑制剂中间体共晶或盐及其制备方法和应用 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5038509B1 (https=) | 1970-10-21 | 1975-12-10 | ||
| JPS538509A (en) | 1976-07-13 | 1978-01-26 | Toshiba Corp | Impedance matching system for data transmission circuit |
| JPS6019759B2 (ja) | 1977-11-24 | 1985-05-17 | イ−ライ・リリ−・アンド・カンパニ− | 非経口投予用１１１１５１５２１３９１９９東京都中央区京橋２丁目３番１３号 |
| GB1589317A (en) | 1977-11-24 | 1981-05-13 | Lilly Co Eli | Freeze drying cephalothin sodium |
| JPS60255723A (ja) | 1984-05-31 | 1985-12-17 | Ono Pharmaceut Co Ltd | メシル酸ガベキサートの結晶性凍結乾燥製剤及びその製造方法 |
| JPH07117533B2 (ja) | 1985-08-28 | 1995-12-18 | 株式会社生体科学研究所 | トランスフエリンおよびその用途 |
| US20030220521A1 (en) | 1989-07-27 | 2003-11-27 | G.D. Searle & Co. | Renal-selective prodrugs for control of renal sympathetic nerve activity in the treatment of hypertension |
| TW264475B (https=) | 1991-09-20 | 1995-12-01 | Takeda Pharm Industry Co Ltd | |
| CZ282567B6 (cs) * | 1993-12-29 | 1997-08-13 | Pfizer Inc. | Diazabicyklické sloučeniny a farmaceutické prostředky na jejich bázi |
| JP2843444B2 (ja) | 1994-05-02 | 1999-01-06 | 塩野義製薬株式会社 | ピロリジルチオカルバペネム誘導体の結晶，該結晶を含む凍結乾燥製剤，およびその製造方法 |
| AU700545B2 (en) | 1994-05-02 | 1999-01-07 | Shionogi & Co., Ltd. | Crystal of pyrrolidylthiocarbapenem derivative, lyophilized preparation containing said crystal, and process for producing the same |
| FR2812635B1 (fr) | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| FR2815420B1 (fr) | 2000-10-16 | 2003-05-16 | Cit Alcatel | Compensation de la dispersion chromatique dans un systeme de transmission a fibre optique, et fibre de compensation |
| FR2825705B1 (fr) | 2001-06-08 | 2005-05-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens |
| FR2835186B1 (fr) | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
| FR2921060B1 (fr) | 2007-09-14 | 2012-06-15 | Novexel | Nouveau procede de preparation d'une piperidine disubsituee et nouveaux intermediaires |
| WO2009091856A2 (en) | 2008-01-18 | 2009-07-23 | Merck & Co., Inc. | Beta-lactamase inhibitors |
| FR2930553B1 (fr) | 2008-04-29 | 2010-05-21 | Novexel | Composes azabicycliques, leur preparation et leur utilisation comme medicaments, notamment inhibiteurs de beta-lactamases |
| FR2936798B1 (fr) | 2008-10-03 | 2012-09-28 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens. |
| US20120053350A1 (en) | 2009-04-30 | 2012-03-01 | Ian Mangion | Preparation of alkyl esters of n-protected oxo-azacycloalkylcarboxylic acids |
| FR2951171A1 (fr) | 2009-10-09 | 2011-04-15 | Novexel | Nouveau sel de sodium d'un compose azabicyclique sous forme enantiomere cristallisee et nouvelles formes polymorphes et pseudopolymorphes ainsi que leur preparation |
| JP2012122603A (ja) | 2010-11-15 | 2012-06-28 | Nifco Inc | コネクタ装置 |
| US8772490B2 (en) | 2010-12-22 | 2014-07-08 | Meiji Seika Pharma Co., Ltd. | Optically active diazabicyclooctane derivatives and process for preparing the same |
| PL2657234T3 (pl) * | 2010-12-22 | 2017-06-30 | Meiji Seika Pharma Co., Ltd. | Optycznie czynna pochodna diazabicyklooktanowa i sposób jej wytwarzania |
| RU2610091C2 (ru) | 2011-06-17 | 2017-02-07 | Астразенека Аб | (2S,5R)-5-[(бензилокси)амино]пиперидин-2-карбоксамид |
| MX348974B (es) | 2011-08-27 | 2017-07-04 | Wockhardt Ltd | Derivados 1,6 - diazabiciclo [3,2,1] octan-7-ona y su uso en el tratamiento de infecciones bacterianas. |
| CA2845108C (en) | 2011-08-30 | 2015-06-16 | Wockhardt Limited | 1,6-diazabicyclo[3,2,1]octan-7-one derivatives and their use in the treatment of bacterial infections |
| CA2846107C (en) | 2011-09-13 | 2016-06-21 | Wockhardt Limited | Nitrogen containing compounds and their use |
| US8796257B2 (en) | 2011-12-02 | 2014-08-05 | Naeja Pharmaceutical Inc. | Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors |
| US9505761B2 (en) | 2011-12-02 | 2016-11-29 | Fedora Pharmaceuticals Inc. | Bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors |
| HUE046893T2 (hu) | 2012-05-30 | 2020-04-28 | Meiji Seika Pharma Co Ltd | Új ß-laktamáz inhibitor és eljárás elõállítására |
| JP6453222B2 (ja) | 2013-09-24 | 2019-01-16 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | ジアザビシクロオクタン誘導体の製造法とその中間体 |
| ES2901198T3 (es) | 2013-10-08 | 2022-03-21 | Meiji Seika Pharma Co Ltd | Formas cristalinas de derivado de diazabiciclooctano y procedimiento de producción de las mismas |
-
2014
- 2014-09-24 JP JP2015539238A patent/JP6453222B2/ja active Active
- 2014-09-24 US US15/023,976 patent/US10000491B2/en active Active
- 2014-09-24 TW TW103132937A patent/TWI644908B/zh active
- 2014-09-24 EP EP14847854.8A patent/EP3050883B1/en active Active
- 2014-09-24 MY MYPI2016700980A patent/MY176278A/en unknown
- 2014-09-24 MY MYPI2019004461A patent/MY193210A/en unknown
- 2014-09-24 WO PCT/JP2014/075203 patent/WO2015046207A1/ja not_active Ceased
- 2014-09-24 HU HUE14847854A patent/HUE049027T2/hu unknown
- 2014-09-24 AR ARP140103525A patent/AR097744A1/es active IP Right Grant
- 2014-09-24 KR KR1020167009769A patent/KR102239725B1/ko active Active
- 2014-09-24 CN CN201480052097.9A patent/CN105555787B/zh active Active
- 2014-09-24 CA CA2924953A patent/CA2924953C/en active Active
- 2014-09-24 MX MX2016003867A patent/MX367578B/es active IP Right Grant
- 2014-09-24 AU AU2014324302A patent/AU2014324302B2/en active Active
- 2014-09-24 ES ES14847854T patent/ES2793201T3/es active Active
- 2014-09-24 NZ NZ718009A patent/NZ718009A/en unknown
- 2014-09-24 DK DK14847854.8T patent/DK3050883T3/da active
- 2014-09-24 RU RU2016115767A patent/RU2719480C2/ru active
- 2014-09-24 CN CN201710665418.8A patent/CN107501264A/zh active Pending
- 2014-09-24 MX MX2019006550A patent/MX372585B/es unknown
- 2014-09-24 SG SG11201602256UA patent/SG11201602256UA/en unknown
- 2014-09-24 BR BR112016006246A patent/BR112016006246B8/pt active IP Right Grant
-
2016
- 2016-03-23 IL IL244740A patent/IL244740B/en active IP Right Grant
- 2016-03-29 ZA ZA2016/02053A patent/ZA201602053B/en unknown
- 2016-06-24 HK HK18103950.2A patent/HK1244487A1/zh unknown
-
2017
- 2017-06-05 US US15/613,620 patent/US10000492B2/en active Active
-
2023
- 2023-11-28 AR ARP230103209A patent/AR131190A2/es unknown
- 2023-11-28 AR ARP230103208A patent/AR131189A2/es unknown
- 2023-11-28 AR ARP230103205A patent/AR131186A2/es unknown
- 2023-11-28 AR ARP230103207A patent/AR131188A2/es unknown
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