HUE032917T2 - 1-es típusú interferon diagnosztikum - Google Patents

1-es típusú interferon diagnosztikum

Info

Publication number
HUE032917T2
HUE032917T2 HUE10814513A HUE10814513A HUE032917T2 HU E032917 T2 HUE032917 T2 HU E032917T2 HU E10814513 A HUE10814513 A HU E10814513A HU E10814513 A HUE10814513 A HU E10814513A HU E032917 T2 HUE032917 T2 HU E032917T2
Authority
HU
Hungary
Prior art keywords
interferon
diagnostic
type
interferon diagnostic
Prior art date
Application number
HUE10814513A
Other languages
English (en)
Hungarian (hu)
Inventor
Brandon Higgs
Wei Zhu
Chris Morehouse
Barbara White
Bahija Jallal
Yihong Yao
Original Assignee
Medimmune Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Llc filed Critical Medimmune Llc
Publication of HUE032917T2 publication Critical patent/HUE032917T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39583Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials not provided for elsewhere, e.g. haptens, coenzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HUE10814513A 2009-09-03 2010-09-02 1-es típusú interferon diagnosztikum HUE032917T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23963009P 2009-09-03 2009-09-03

Publications (1)

Publication Number Publication Date
HUE032917T2 true HUE032917T2 (hu) 2017-11-28

Family

ID=43649646

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE10814513A HUE032917T2 (hu) 2009-09-03 2010-09-02 1-es típusú interferon diagnosztikum

Country Status (23)

Country Link
US (3) US20120251546A1 (enExample)
EP (1) EP2473636B1 (enExample)
JP (2) JP5727484B2 (enExample)
KR (1) KR20120101340A (enExample)
CN (1) CN102753704A (enExample)
AU (1) AU2010289383B2 (enExample)
BR (1) BR112012004781A2 (enExample)
CA (1) CA2772921A1 (enExample)
CY (1) CY1118566T1 (enExample)
DK (1) DK2473636T3 (enExample)
ES (1) ES2613055T3 (enExample)
HR (1) HRP20170091T1 (enExample)
HU (1) HUE032917T2 (enExample)
LT (1) LT2473636T (enExample)
ME (1) ME02599B (enExample)
MX (1) MX2012002640A (enExample)
PL (1) PL2473636T3 (enExample)
PT (1) PT2473636T (enExample)
RS (1) RS55641B1 (enExample)
RU (1) RU2012112802A (enExample)
SI (1) SI2473636T1 (enExample)
SM (2) SMT201700063T1 (enExample)
WO (1) WO2011028933A1 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003237889A1 (en) * 2002-06-11 2003-12-22 Idaho Research Foundation Type i interferon-inducible proteins to detect viral infection
EP2077858A4 (en) * 2006-12-06 2011-07-20 Medimmune Llc INTERFERON ALPHA-INDUCED PHARMACODYNAMIC MARKERS
JP2010526107A (ja) * 2007-05-03 2010-07-29 メディミューン,エルエルシー 自己免疫疾患の自己抗体マーカー
EP2701742A4 (en) * 2011-04-26 2015-03-18 Genentech Inc COMPOSITIONS AND METHOD FOR TREATING AUTOIMMUNE DISEASES
WO2013101771A2 (en) * 2011-12-30 2013-07-04 Genentech, Inc. Compositions and method for treating autoimmune diseases
US9493570B2 (en) * 2012-06-13 2016-11-15 Medimmune, Llc Fixed dosage regimens for anti-type I interferon receptor (IFNAR) antibodies
JP6531306B2 (ja) * 2015-02-20 2019-06-19 一三 西野 炎症性筋疾患鑑別マーカー及びそれを用いた炎症性筋疾患と非炎症性筋疾患の鑑別方法
CN105316404B (zh) * 2015-02-27 2017-02-22 中南大学湘雅二医院 系统性红斑狼疮生物标志物及其诊断试剂盒
MX2018010771A (es) 2016-03-10 2019-05-15 Viela Bio Inc Moleculas de union al transcrito 7 similar a inmunoglobulina (ilt7) y metodos de uso de las mismas.
CN105567861B (zh) * 2016-03-16 2018-12-14 宫蕊 Ifi27作为冠心病诊断标志物的用途
WO2020165437A1 (en) * 2019-02-15 2020-08-20 Astrazeneca Ab Type i interferon-mediated disorders
EP4058060B1 (en) 2019-11-11 2025-02-19 Astrazeneca AB Type i interferon inhibition in systemic lupus erythematosus
EP4566667A3 (en) 2020-05-29 2025-09-03 AstraZeneca AB Treatment of cardiometabolic disease with inhibitors of type i interferon signalling
CN116234553A (zh) * 2020-10-02 2023-06-06 新基公司 治疗系统性红斑狼疮的方法和作为对疗法临床敏感性的预测指标的生物标志物的用途
TW202237647A (zh) 2020-10-08 2022-10-01 瑞典商阿斯特捷利康公司 狼瘡發作之治療
AU2021383537A1 (en) 2020-11-18 2023-06-29 Astrazeneca Ab Steroid sparing
PL4192882T3 (pl) 2021-04-23 2025-04-28 Astrazeneca Ab Leczenie toczniowego zapalenia nerek przeciwciałem przeciwko receptorowi typu i inf anifrolumabem
EP4326322A1 (en) 2021-04-23 2024-02-28 Astrazeneca AB Treatment of cutaneous lupus erythematous
KR20250092298A (ko) 2021-04-23 2025-06-23 아스트라제네카 아베 피하 주사용 항-ifnar1 투여 요법
EP4333877A1 (en) * 2021-05-04 2024-03-13 Viela Bio, Inc. Methods of treatment of autoimmune disorders using ilt7 binding proteins
EP4337696A1 (en) 2021-05-12 2024-03-20 Astrazeneca AB Inhibitor of type 1 interferon receptor steroid sparing in systemic lupus erythematosus patients
CA3226744A1 (en) 2021-07-27 2023-02-02 Astrazeneca Ab Treatment of lupus
KR20240082399A (ko) 2021-10-04 2024-06-10 아스트라제네카 아베 루푸스의 치료
AU2023339761A1 (en) 2022-09-14 2025-03-20 Viatris Asia Pacific Pte. Ltd. S1p 1 receptor modulators for use in the treatment of type 1 ifn mediated diseases
JP2025533978A (ja) 2022-10-13 2025-10-09 アストラゼネカ・アクチエボラーグ ループスの治療
WO2024241156A1 (en) 2023-05-19 2024-11-28 Astrazeneca Ab Treatment of lupus
WO2025022280A1 (en) 2023-07-21 2025-01-30 Astrazeneca Ab Treatment of neurodegenerative diseases
GB202315831D0 (en) 2023-10-16 2023-11-29 Astrazeneca Ab Treatment of skin disease
GB202402824D0 (en) 2024-02-28 2024-04-10 Astrazeneca Ab Treatment of chronic kidney disease

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60500864A (ja) 1983-02-04 1985-06-06 ワドリ、テクナラジズ、インコーパレイティド 近縁関係にあるが別個のタンパク質間に存在する共通決定基に対して特異的なハイブリド−マ抗体の製造および特性づけ
GB8303165D0 (en) 1983-02-04 1983-03-09 Secher D S Monoclonal antibody
DE3306060A1 (de) 1983-02-22 1984-08-23 Boehringer Ingelheim International GmbH, 6507 Ingelheim Neue immunglobulin-produzierende hybridzellinien, deren verwendung und verfahren zu deren herstellung
US4885166A (en) 1985-06-11 1989-12-05 Ciba-Geigy Corporation Hybrid interferons
US7247425B2 (en) * 1998-01-30 2007-07-24 Evolutionary Genomics, Llc Methods to identify polynucleotide and polypeptide sequences which may be associated with physiological and medical conditions
US7087726B2 (en) 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies
AU2004293369A1 (en) * 2003-03-03 2005-06-09 Genentech, Inc. Compositions and methods for the treatment of systemic lupus erythematosis
CA2458085A1 (en) * 2003-03-21 2004-09-21 F. Hoffmann-La Roche Ag Transcriptional activity assay
CN1795010A (zh) 2003-04-23 2006-06-28 梅达雷克斯公司 针对α干扰素受体-1(IFNAR-1)的人源化抗体
SI2418220T1 (sl) 2003-12-10 2017-10-30 E. R. Squibb & Sons, L.L.C. Interferon alfa protitelesa in njihova uporaba
EP1730308A4 (en) * 2004-03-05 2008-10-08 Rosetta Inpharmatics Llc CLASSIFICATION OF BREAST CANCER PATIENTS USING A COMBINATION OF CLINICAL CRITERIA AND INFORMATIVE SKILLS
PT1781705E (pt) 2004-06-21 2014-12-23 Medarex Llc Anticorpos contra recetor i do interferão alfa e as suas utilizações
PT2327792E (pt) * 2005-08-05 2013-11-21 Genentech Inc Métodos e composições para a detecção de distúrbios autoimunes
US8211649B2 (en) * 2006-03-31 2012-07-03 Human Genome Sciences, Inc. Methods of diagnosing and prognosing hodgkin's lymphoma
WO2008016356A2 (en) * 2006-08-02 2008-02-07 Genizon Biosciences Genemap of the human genes associated with psoriasis
EP2077858A4 (en) * 2006-12-06 2011-07-20 Medimmune Llc INTERFERON ALPHA-INDUCED PHARMACODYNAMIC MARKERS
JP2010526107A (ja) * 2007-05-03 2010-07-29 メディミューン,エルエルシー 自己免疫疾患の自己抗体マーカー
US20100209914A1 (en) * 2007-05-25 2010-08-19 Ore Pharmaceuticals , Inc. Methods, systems, and kits for evaluating multiple sclerosis
CA2714410A1 (en) * 2008-02-08 2009-08-13 Medimmune, Llc Disease markers and uses thereof
WO2009130176A1 (en) * 2008-04-21 2009-10-29 Novartis Forschungsstiftung Zweigniederlassung Friedrich Miescher Institute For Biomedical Research Antiviral Therapy
US20090325176A1 (en) * 2008-06-05 2009-12-31 Wyeth Gene Expression Profiles Associated with Asthma Exacerbation Attacks

Also Published As

Publication number Publication date
CN102753704A (zh) 2012-10-24
CY1118566T1 (el) 2017-07-12
LT2473636T (lt) 2017-02-10
US20120251546A1 (en) 2012-10-04
BR112012004781A2 (pt) 2017-02-14
ES2613055T3 (es) 2017-05-22
PL2473636T3 (pl) 2017-05-31
EP2473636B1 (en) 2016-10-26
PT2473636T (pt) 2017-02-06
RS55641B1 (sr) 2017-06-30
RU2012112802A (ru) 2013-10-10
ME02599B (me) 2017-06-20
US20160024205A1 (en) 2016-01-28
CA2772921A1 (en) 2011-03-10
JP2013503642A (ja) 2013-02-04
DK2473636T3 (en) 2017-02-06
WO2011028933A1 (en) 2011-03-10
EP2473636A4 (en) 2013-02-27
AU2010289383B2 (en) 2015-04-16
JP5727484B2 (ja) 2015-06-03
EP2473636A1 (en) 2012-07-11
HRP20170091T1 (hr) 2017-03-24
AU2010289383A1 (en) 2012-04-19
MX2012002640A (es) 2012-06-25
JP2015147788A (ja) 2015-08-20
US20150191788A1 (en) 2015-07-09
SI2473636T1 (sl) 2017-04-26
SMT201700063T1 (it) 2017-03-08
SMT201700063B (it) 2017-03-08
KR20120101340A (ko) 2012-09-13

Similar Documents

Publication Publication Date Title
HUE032917T2 (hu) 1-es típusú interferon diagnosztikum
BR112012012872A2 (pt) "pirrolindinas de espiroindolinona"
BRPI1011813A2 (pt) "inalador"
PL2414015T4 (pl) System laryngoskopowy
FR2941508B1 (fr) Agencement d'entrainement
BR112012007164A2 (pt) "veículo"
EP2263545A4 (en) sonographer
BR112012004444A2 (pt) "laringoscópio"
BRPI1013030A2 (pt) "aquecedores"
UY33125A (es) Diaza-espiro-[5,5]-undecanos
FR2950411B1 (fr) Agencement d'entrainement
FR2944062B1 (fr) Injecteur d'ergols
PL2090199T3 (pl) Tułów
BR112013010223A2 (pt) "piranosidade temperatura- estável"
IT1397132B1 (it) Composizioni comprendenti antiinfiammatori non steroidei.
FI20096108L (fi) Järjestely
BRPI1013017A2 (pt) "17beta-alquil-17alfa-óxi-estratrienos"
BRPI1013544A2 (pt) compostos com efeito fisiológico
IT1398148B1 (it) "auto-negozio"
FR2940753B3 (fr) L'eco-sapin
CN301207115S (zh) 牙刷(13)
EE01008U1 (et) M„nguklots
FI8535U1 (fi) Taajuusmuuttajajärjestely
TH105749B (th) ไทรซับสทิทิวเทด 1,2,4 ไทรแอโซล
FI20095478A0 (fi) Kaasupesuri