HUE027924T2 - Fraxinus excelsior magok extraktuma és terápiás alkalmazása - Google Patents
Fraxinus excelsior magok extraktuma és terápiás alkalmazása Download PDFInfo
- Publication number
- HUE027924T2 HUE027924T2 HUE13180284A HUE13180284A HUE027924T2 HU E027924 T2 HUE027924 T2 HU E027924T2 HU E13180284 A HUE13180284 A HU E13180284A HU E13180284 A HUE13180284 A HU E13180284A HU E027924 T2 HUE027924 T2 HU E027924T2
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- HU
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- Prior art keywords
- extract
- treatment
- excelsior
- fraxinus
- condition
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- C—CHEMISTRY; METALLURGY
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- C07H1/00—Processes for the preparation of sugar derivatives
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- C—CHEMISTRY; METALLURGY
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- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A—HUMAN NECESSITIES
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- A61K2236/30—Extraction of the material
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- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
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- A61K2236/30—Extraction of the material
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- A—HUMAN NECESSITIES
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
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- Organic Chemistry (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
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- Hematology (AREA)
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- Molecular Biology (AREA)
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- Botany (AREA)
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- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Claims (3)
- Fraxîrsus excelsior magok axtraktuma és terápiás alkalmazásé Sxaieialmi igénypontok:1. Fraxinus excelsior mag extraktum, amely tartalmaz: körülbelül 1 íömeg% - körülbelül 15 tömeg% nuzenidef, körülbelül 1 tömeg% “körülbelül 1? tömeg % Gí3-ai körülbelül 0,5 tömeglé - körülbelül 1 tömeg% oleozld-metü-észtert, körülbelül 0,03 tőmeg% - körülbelül S, 12 tömeg% excelszid B4, körülbelül 0,1 tömegé körülbelül 1,7 tömeg% Gl®-őt, és körülbelül 0,il töroeglí? “ körülbelül 0,7 tömeg% szaliörozidot. 2v á? 1, igénypont szerinti Fraxinus excelsior mag extraktum gyógyszerként való alkalmazásra. 3« Az 1. Igénypont szerinti Fraxinus excelsior mag extraktum valamely állapot kezelésében való alkalmazásra PPAR-alfa receptorok aktiválásával, ahol: (A) a kezelés: (I) hipogiikémiás aktivitás kiváltása; |ii| inzulin-érzékenység elősegítése; Pl éhgyomri plazrna-inzulínszintek kontrollálása hiperínzuiioémla ellen; vagy (ív) hiperínzuiinémia: mégilőzésé; vagy (B) az állapot: (a) anyagcsere szindróma; vagy (b) 2 típusú diabetes mellitus, 4> Az 1 igénypont szerinti Fraxinus excelsior mag extraktum alkalmazása gyógyszer előállítására valamely állapot PPAR-alfa receptorok aktiválásával való kezelésére., ahol (A) a kezelés: (1) hipogiikémiás aktivitás kiváltása; (ti) Inzulin-érzékenység elősegítése; Pl éhgyomri plazniaánzuiinszíntek kontrollálása hiperínzuiinémia ellen; vagy (Ív) bpennzullnimia méielőzesé;; vagy (B) az állapét:: (a) anyagcsere szindróma; vagy (b) 2 típusú diabetes mellitus. ük Az alkalmazásra szolgáló extraktum a 3. igénypont szerint és a 4. igénypont szerinti alkalmazás, ahol a kezelés orális adagolás étkezés elolt,
- 6, Az 1. Igénypont szerinti Fraxious excelsior mag extraktum valamely állapot kezelésében való alkalmazásra a zslrszintézis blokkolásával, ahol a kezelés testtömegét kontrolláló vagy testzsirt csökkenté terápiás eljárás.. ?.. Az 1. igénypont szerinti Fraxious excelsior mag extraktum alkalmazása gyógyszer előállítására valamely állapot kezelésére zsirszintézis blokkolásával, ahol a kezelés testtömeget kontrolláló vagy testzsirt csökkentő terápiás eljárás,
- 8, Az alkalmazásra szolgáló extraktum a 8, igénypont szerint és a ?. igénypont szerinti alkalmazás, ahol a kezelés orális adagolás étkezés előtt, i. Az alkalmazásra szolgáié extraktum vagy alkalmazás a 2-8. igénypontok bármelyike szerint, ahol az alkalmazás emberben történik.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98555807P | 2007-11-05 | 2007-11-05 | |
| US12/185,649 US8142826B2 (en) | 2007-11-05 | 2008-08-04 | Extract of Fraxinus excelsior seeds and therapeutic applications therefor |
Publications (1)
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| HUE027924T2 true HUE027924T2 (hu) | 2016-11-28 |
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| HUE13180284A HUE027924T2 (hu) | 2007-11-05 | 2008-11-05 | Fraxinus excelsior magok extraktuma és terápiás alkalmazása |
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| Country | Link |
|---|---|
| US (2) | US8142826B2 (hu) |
| EP (2) | EP2214790B1 (hu) |
| JP (4) | JP5859205B2 (hu) |
| KR (1) | KR20100088634A (hu) |
| CN (2) | CN101918080B (hu) |
| AU (1) | AU2008323968B2 (hu) |
| BR (1) | BRPI0820490A2 (hu) |
| CA (1) | CA2704640C (hu) |
| ES (2) | ES2439706T3 (hu) |
| HK (2) | HK1147223A1 (hu) |
| HU (1) | HUE027924T2 (hu) |
| PT (1) | PT2664361E (hu) |
| RU (1) | RU2523905C2 (hu) |
| WO (1) | WO2009061849A1 (hu) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107496469A (zh) | 2011-10-06 | 2017-12-22 | 狮王株式会社 | 睡眠质量改善剂 |
| JP6096439B2 (ja) * | 2012-08-31 | 2017-03-15 | ライオン株式会社 | 成長ホルモン分泌促進剤 |
| KR102254120B1 (ko) * | 2013-03-27 | 2021-05-20 | 삼성전자주식회사 | 애플리케이션의 실행 결과를 표시하는 디바이스 및 방법 |
| KR102382074B1 (ko) * | 2013-10-18 | 2022-04-04 | 삼성전자주식회사 | 멀티윈도우 운용 방법 및 이를 지원하는 전자 장치 |
| CN104758365A (zh) * | 2014-12-06 | 2015-07-08 | 西北大学 | 一种大叶白蜡树种子中降血糖物质裂环烯醚萜苷类化合物的提取制备方法 |
| CN105748496B (zh) * | 2016-01-25 | 2018-07-03 | 西北大学 | 大叶白蜡树种子化学成分标准化的提取物及其制备方法和应用 |
| GB2552493A (en) * | 2016-07-25 | 2018-01-31 | Naturex Sa | New uses and methods |
| WO2019019043A1 (zh) | 2017-07-26 | 2019-01-31 | 鼎科医疗技术（苏州）有限公司 | 一种表面液化药物涂层球囊 |
| KR20230082445A (ko) | 2021-12-01 | 2023-06-08 | 박종원 | 탈부착가능한 세제받이와 뚜껑에 스포이드를 결합한 액체 세제 용기 |
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| US5376372A (en) * | 1989-07-11 | 1994-12-27 | Steigerwald Arzneimittelwerk Gmbh | Analgesic and inflammation-reducing medicament |
| JP2002153238A (ja) * | 2000-11-21 | 2002-05-28 | Nippon Shinyaku Co Ltd | 食品、飼料及び医薬組成物 |
| EP1407679A4 (en) | 2001-06-21 | 2005-06-15 | Kyowa Hakko Kogyo Kk | METHOD FOR PRODUCING PLANT EXTRACT CONTAINING PLANT POWDER |
| US7030092B1 (en) * | 2001-08-24 | 2006-04-18 | Small Giant L.L.C. | Ultra-high fiber supplement and method of reducing weight cardiovascular risks and ingested toxins. |
| US7297715B2 (en) | 2002-07-30 | 2007-11-20 | Merck & Co., Inc. | PPAR alpha selective compounds for the treatment of dyslipidemia and other lipid disorders |
| CN1942097A (zh) | 2005-01-21 | 2007-04-04 | 西斯汀财产有限公司 | 富含根皮苷的植物提取物及使用该提取物调整血糖含量和抗衰老的方法 |
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- 2008-11-05 RU RU2010122894/15A patent/RU2523905C2/ru active
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2011
- 2011-02-09 HK HK11101245.8A patent/HK1147223A1/xx unknown
- 2011-11-10 US US13/294,058 patent/US8293292B2/en active Active
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2013
- 2013-09-17 JP JP2013191394A patent/JP6226459B2/ja active Active
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2014
- 2014-05-19 HK HK14104661.4A patent/HK1191281A1/xx unknown
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2015
- 2015-08-03 JP JP2015153084A patent/JP2015193665A/ja active Pending
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2017
- 2017-03-01 JP JP2017038414A patent/JP2017101070A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP6226459B2 (ja) | 2017-11-08 |
| US8142826B2 (en) | 2012-03-27 |
| US8293292B2 (en) | 2012-10-23 |
| WO2009061849A1 (en) | 2009-05-14 |
| JP2014012723A (ja) | 2014-01-23 |
| EP2214790A4 (en) | 2011-11-30 |
| US20120058210A1 (en) | 2012-03-08 |
| RU2523905C2 (ru) | 2014-07-27 |
| EP2214790A1 (en) | 2010-08-11 |
| JP2015193665A (ja) | 2015-11-05 |
| AU2008323968B2 (en) | 2013-11-28 |
| CN101918080B (zh) | 2014-10-01 |
| BRPI0820490A2 (pt) | 2017-05-23 |
| EP2664361A1 (en) | 2013-11-20 |
| JP2011503009A (ja) | 2011-01-27 |
| PT2664361E (pt) | 2015-10-20 |
| KR20100088634A (ko) | 2010-08-09 |
| AU2008323968A1 (en) | 2009-05-14 |
| CN104474029A (zh) | 2015-04-01 |
| HK1147223A1 (en) | 2011-08-05 |
| HK1191281A1 (en) | 2014-07-25 |
| JP2017101070A (ja) | 2017-06-08 |
| US20090117214A1 (en) | 2009-05-07 |
| ES2439706T3 (es) | 2014-01-24 |
| CN101918080A (zh) | 2010-12-15 |
| ES2550335T3 (es) | 2015-11-06 |
| EP2214790B1 (en) | 2013-10-02 |
| EP2664361B1 (en) | 2015-07-29 |
| RU2010122894A (ru) | 2011-12-20 |
| CA2704640C (en) | 2016-12-13 |
| CA2704640A1 (en) | 2009-05-14 |
| JP5859205B2 (ja) | 2016-02-10 |
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