HUE025483T2 - Relaxin for use in the treatment of dyspnoea associated with acute heart failure - Google Patents
Relaxin for use in the treatment of dyspnoea associated with acute heart failure Download PDFInfo
- Publication number
- HUE025483T2 HUE025483T2 HUE09747740A HUE09747740A HUE025483T2 HU E025483 T2 HUE025483 T2 HU E025483T2 HU E09747740 A HUE09747740 A HU E09747740A HU E09747740 A HUE09747740 A HU E09747740A HU E025483 T2 HUE025483 T2 HU E025483T2
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- Prior art keywords
- relaxin
- patients
- ahf
- heart failure
- acute
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- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
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| US12788908P | 2008-05-16 | 2008-05-16 | |
| US19054508P | 2008-08-28 | 2008-08-28 | |
| US20124008P | 2008-12-08 | 2008-12-08 | |
| US16433309P | 2009-03-27 | 2009-03-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE025483T2 true HUE025483T2 (en) | 2016-02-29 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE09747740A HUE025483T2 (en) | 2008-05-16 | 2009-05-15 | Relaxin for use in the treatment of dyspnoea associated with acute heart failure |
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| HR (1) | HRP20150845T1 (https=) |
| HU (1) | HUE025483T2 (https=) |
| IL (3) | IL208992A (https=) |
| MA (1) | MA32389B1 (https=) |
| MX (1) | MX2010012450A (https=) |
| MY (2) | MY159803A (https=) |
| NZ (3) | NZ589009A (https=) |
| PL (1) | PL2288373T3 (https=) |
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| SG (2) | SG10201609580YA (https=) |
| SI (1) | SI2288373T1 (https=) |
| TW (1) | TWI386202B (https=) |
| UA (1) | UA99953C2 (https=) |
| WO (1) | WO2009140659A2 (https=) |
| ZA (1) | ZA201007449B (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
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| BRPI0912559A2 (pt) * | 2008-05-16 | 2015-10-13 | Corthera Inc | método de tratar insuficiência cardíaca crônica |
| CA2724540C (en) | 2008-05-16 | 2014-07-08 | Corthera, Inc. | Treating dyspnea associated with acute heart failure with relaxin |
| EP2544706B1 (en) | 2010-03-10 | 2015-06-17 | The University Of Melbourne | Modulating aquaporins with relaxin |
| US9465039B2 (en) | 2010-08-06 | 2016-10-11 | Mycartis Nv | Perlecan as a biomarker for renal dysfunction |
| EA030886B1 (ru) * | 2010-08-17 | 2018-10-31 | Амбркс, Инк. | Модифицированные полипептиды релаксина, содержащие некодируемую в природе аминокислоту, связанную с полимером, и их применение |
| US9567386B2 (en) | 2010-08-17 | 2017-02-14 | Ambrx, Inc. | Therapeutic uses of modified relaxin polypeptides |
| RU2014103288A (ru) * | 2011-07-01 | 2015-08-10 | Байер Интеллектчуал Проперти Гмбх | Слитые полипептиды релаксина и их применение |
| AU2013202269A1 (en) * | 2011-10-26 | 2013-05-16 | Howard Florey Institute Of Experimental Physiology And Medicine | Compositions and methods for the treatment of fibrosis and fibrotic diseases |
| CA2864100A1 (en) * | 2012-02-14 | 2013-08-22 | The Regents Of The University Of California | Systemic delivery and regulated expression of paracrine genes for cardiovascular diseases and other conditions |
| US9452973B2 (en) | 2012-05-04 | 2016-09-27 | The United States Of America, As Represented By The Secretary Department Of Health And Human Services | Modulators of the relaxin receptor 1 |
| KR102299073B1 (ko) * | 2012-10-26 | 2021-09-09 | 치에시 파마슈티시 에스.피.아. | 심부전에서 혈압을 조절하고 호흡곤란을 감소시키는 방법 |
| PT2981258T (pt) * | 2013-04-05 | 2020-10-19 | Scpharmaceuticals Inc | Formulações farmacêuticas para administração subcutânea de furosemida |
| US9707154B2 (en) | 2013-04-24 | 2017-07-18 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
| MX2016010087A (es) * | 2014-02-03 | 2016-10-07 | Novartis Ag | Filtros para equipos de infusion. |
| EP2946788A1 (en) * | 2014-05-23 | 2015-11-25 | Immundiagnostik AG | Method and composition for treating heart failure with preserved ejection fraction |
| US20170100460A1 (en) * | 2014-06-13 | 2017-04-13 | Novartis Ag | Use of serelaxin to reduce gdf-15 |
| PT3387019T (pt) | 2015-12-09 | 2022-01-14 | Scripps Research Inst | Proteínas de fusão de imunoglobulina de relaxina e métodos de uso |
| WO2017139164A1 (en) | 2016-02-12 | 2017-08-17 | Cardiac Pacemakers, Inc. | Systems and methods for patient monitoring |
| PE20191716A1 (es) | 2017-02-08 | 2019-12-05 | Bristol Myers Squibb Co | Polipeptidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos |
| US11832970B2 (en) | 2017-07-26 | 2023-12-05 | Cardiac Pacemakers, Inc. | Worsening heart failure stratification |
| CN107335051A (zh) * | 2017-08-18 | 2017-11-10 | 温州医科大学附属第医院 | 一种保护慢性心衰肾功能的药物组合物 |
| ES3041602T3 (en) | 2018-12-10 | 2025-11-13 | Sq Innovation Ag | Pharmaceutical compositions of furosemide and uses thereof |
| US12397005B2 (en) | 2019-01-04 | 2025-08-26 | Sq Innovation Ag | Pharmaceutical compositions of torsemide and uses thereof |
| US11246851B2 (en) | 2019-01-04 | 2022-02-15 | Sq Innovation Ag | Pharmaceutical compositions of furosemide and uses thereof |
| PH12021551811A1 (en) | 2019-01-31 | 2022-03-21 | Scpharmaceuticals Inc | Concentrated liquid pharmaceutical formulations of furosemide and methods of administering the same |
| JP2025528469A (ja) | 2022-08-31 | 2025-08-28 | リラクセラ ファルマツォイティッシュ ゲゼルシャフト エムベーハー ウント コー． カーゲー | 免疫抑制薬及び処置方法 |
| WO2025056188A1 (en) | 2023-09-15 | 2025-03-20 | Relaxera Pharmazeutische Gmbh & Co. Kg | Relaxin medication |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5023321A (en) | 1982-12-13 | 1991-06-11 | Howard Florey Institute Of Experimental Physiology & Medicine | Molecular cloning and characterization of a further gene sequence coding for human relaxin |
| US5166191A (en) * | 1991-08-19 | 1992-11-24 | Genentech, Inc. | Use of relaxin in cardiovascular therapy |
| US5478807A (en) * | 1991-08-19 | 1995-12-26 | Genentech, Inc. | Use of relaxin in the treatment of bradycardia |
| WO1995000645A2 (en) | 1993-06-21 | 1995-01-05 | Genentech, Inc. | Process for producing relaxin |
| US5952296A (en) * | 1993-07-27 | 1999-09-14 | Bigazzi; Mario | Method of using relaxin as therapeutic or preventing agent |
| US5760069A (en) | 1995-02-08 | 1998-06-02 | Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 | Method of treatment for decreasing mortality resulting from congestive heart failure |
| US5811395A (en) | 1995-06-07 | 1998-09-22 | Medical University Of South Carolina | Relaxin analogs and derivatives methods and uses thereof |
| CA2229479C (en) | 1995-08-15 | 2010-03-30 | Connective Therapeutics, Inc. | Method of promoting angiogenesis |
| EP1253929B1 (en) * | 2000-02-09 | 2007-05-23 | BAS Medical, Inc. | Use of relaxin to treat diseases related to vasoconstriction |
| DE10155843A1 (de) | 2000-11-16 | 2003-01-30 | Immundiagnostik Ag | Verfahren zur Prognose und Diagnose von Herzinsuffizienz |
| US20050113286A1 (en) * | 2002-03-18 | 2005-05-26 | Schreiner George F. | Methods for treating congestive heart failure |
| US7878978B2 (en) | 2004-03-18 | 2011-02-01 | University Of Pittsburgh- Of The Commonwealth System Of Higher Education | Use of relaxin to increase arterial compliance |
| EP1729817B1 (en) * | 2004-03-30 | 2014-03-05 | Industry-Academic Cooperation Foundation | Gene delivery system containing relaxin gene and pharmaceutical composition using relaxin |
| US20060264367A1 (en) | 2005-05-21 | 2006-11-23 | Howard Florey Institute | Prevention of fibrosis following cardiac injury |
| TW200800206A (en) | 2005-07-11 | 2008-01-01 | Abbott Lab | Methods for determining how to treat congestive heart failure |
| WO2009007848A2 (en) | 2007-07-12 | 2009-01-15 | Compugen Ltd. | Bioactive peptides and method of using same |
| CA2724540C (en) * | 2008-05-16 | 2014-07-08 | Corthera, Inc. | Treating dyspnea associated with acute heart failure with relaxin |
| BRPI0912559A2 (pt) | 2008-05-16 | 2015-10-13 | Corthera Inc | método de tratar insuficiência cardíaca crônica |
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