HU9600240D0 - Variant phosphoenolpyruvate carboxylase, gene thereof, and process for producing amino acid - Google Patents

Variant phosphoenolpyruvate carboxylase, gene thereof, and process for producing amino acid

Info

Publication number
HU9600240D0
HU9600240D0 HU9600240A HU9600240A HU9600240D0 HU 9600240 D0 HU9600240 D0 HU 9600240D0 HU 9600240 A HU9600240 A HU 9600240A HU 9600240 A HU9600240 A HU 9600240A HU 9600240 D0 HU9600240 D0 HU 9600240D0
Authority
HU
Hungary
Prior art keywords
gene
amino acid
phosphoenolpyruvate carboxylase
carboxylase
variant
Prior art date
Application number
HU9600240A
Other languages
English (en)
Other versions
HUT73690A (en
HU219600B (hu
Inventor
Hiroshi Matsui
Masakazu Sugimoto
Tomoko Suzuki
Katsura Izui
Tsutomu Toyama
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27320552&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HU9600240(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of HU9600240D0 publication Critical patent/HU9600240D0/hu
Publication of HUT73690A publication Critical patent/HUT73690A/hu
Publication of HU219600B publication Critical patent/HU219600B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/14Glutamic acid; Glutamine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/20Aspartic acid; Asparagine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HU9600240A 1993-08-24 1994-08-17 Mutáns foszfo-enolpiruvát-karboxiláz, ennek génje, valamint eljárás aminosav előállítására HU219600B (hu)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP20977693 1993-08-24
JP20977593 1993-08-24
JP15387694 1994-07-05
PCT/JP1994/001365 WO1995006114A1 (fr) 1993-08-24 1994-08-17 Allele de phosphenolpyruvate carboxylase, gene de cet allele et procede de production de l'acide amine

Publications (3)

Publication Number Publication Date
HU9600240D0 true HU9600240D0 (en) 1996-03-28
HUT73690A HUT73690A (en) 1996-09-30
HU219600B HU219600B (hu) 2001-05-28

Family

ID=27320552

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9600240A HU219600B (hu) 1993-08-24 1994-08-17 Mutáns foszfo-enolpiruvát-karboxiláz, ennek génje, valamint eljárás aminosav előállítására

Country Status (15)

Country Link
US (2) US5876983A (hu)
EP (1) EP0723011B1 (hu)
KR (2) KR100337959B1 (hu)
CN (1) CN1179043C (hu)
AT (1) ATE220099T1 (hu)
AU (1) AU682547B2 (hu)
BR (1) BR9407625A (hu)
CA (1) CA2169170C (hu)
CZ (1) CZ289051B6 (hu)
DE (1) DE69430919T2 (hu)
HU (1) HU219600B (hu)
MY (1) MY112250A (hu)
PL (1) PL181380B1 (hu)
SK (1) SK283369B6 (hu)
WO (1) WO1995006114A1 (hu)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6969782B2 (en) 1993-10-06 2005-11-29 Ajinomoto Co., Inc. Method of producing transgenic plants having improved amino acid composition
JPH09285294A (ja) * 1996-04-23 1997-11-04 Ajinomoto Co Inc 発酵法によるl−グルタミン酸の製造法
DE69840678D1 (de) * 1997-07-18 2009-04-30 Ajinomoto Kk Verfahren zur produktion von purinnukleosiden durch fermentation
SK284235B6 (en) 1997-10-04 2004-11-03 Forschungszentrum Juelich Gmbh Method for microbial production of amino acids of the aspartate and/or glutamate family and agents which can be used in the said method
AU756507B2 (en) * 1998-03-18 2003-01-16 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
US20030087381A1 (en) * 1998-04-13 2003-05-08 University Of Georgia Research Foundation, Inc. Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals
EP2194122B1 (en) 1998-04-13 2015-12-02 The University Of Georgia Research Foundation, Inc. Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
AU2203399A (en) * 1998-12-23 2000-07-31 Massachusetts Institute Of Technology Pyruvate carboxylase from (corynebacterium glutamicum)
US6171833B1 (en) 1998-12-23 2001-01-09 Massachusetts Institute Of Technology Pyruvate carboxylase from corynebacterium glutamicum
US6599732B1 (en) 1999-06-29 2003-07-29 Archer-Daniels-Midland Company Regulation of carbon assimilation
MXPA01013445A (es) * 1999-06-29 2002-07-30 Archer Daniels Midland Co Regulacion de la asimilacion de carbono.
BR0012020A (pt) 1999-07-02 2002-07-02 Ajinomoto Kk Proteìna, e, dna
DE19931314A1 (de) * 1999-07-07 2001-01-11 Degussa L-Lysin produzierende coryneforme Bakterien und Verfahren zur Herstellung von Lysin
WO2001027258A2 (en) * 1999-10-13 2001-04-19 The University Of Georgia Research Foundation, Inc. High yield protein expression system and methods
US6727411B2 (en) 1999-12-13 2004-04-27 Ajinomoto Co., Inc. Method of producing transgenic plants having improved amino acid composition
JP4306169B2 (ja) * 1999-12-24 2009-07-29 味の素株式会社 L−アミノ酸の製造法及び新規遺伝子
US6927046B1 (en) 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
ATE411378T1 (de) 2000-01-21 2008-10-15 Ajinomoto Kk Verfahren zur herstellung von l-lysin
US7368266B2 (en) 2001-02-13 2008-05-06 Cj Corporation Method for L-threonine production
KR100397423B1 (ko) * 2001-02-13 2003-09-13 씨제이 주식회사 L-쓰레오닌의 제조방법
US20030115638A1 (en) * 2001-08-17 2003-06-19 Ajinomoto Co., Inc. Plants having increased amino acids content and methods for producing the same
AU2003205041A1 (en) * 2002-07-12 2004-01-29 Ajinomoto Co., Inc. Method for producing target substance by fermentation
BR0304860A (pt) * 2002-11-11 2004-08-31 Ajinomoto Kk Método para produzir uma substância alvo pela utilização de uma-bactéria pertencente ao gênero escherichia
KR100498971B1 (ko) * 2003-04-04 2005-07-04 씨제이 주식회사 염색체 내 tdcBC 및 pckA 유전자가 불활성화된 미생물 및 이를 이용하여 L-쓰레오닌을 제조하는 방법
JP2007532114A (ja) * 2004-04-09 2007-11-15 ジェネンコー・インターナショナル・インク バチルスにおけるpckA修飾および増強されたタンパク質発現
KR100768748B1 (ko) 2004-12-30 2007-10-19 씨제이 주식회사 외래의 nadp 의존적 글리세르알데히드-3-포스페이트디히드로게나제 유전자를 포함하는 에세리키아 종 또는코리네박리움 종 미생물 및 그를 이용하여 l-라이신을생산하는 방법
WO2007017710A1 (en) 2005-08-11 2007-02-15 Metabolic Explorer Process for the preparation of aspartate and derived amino acids like lysine, threonine, isoleucine, methionine, homoserine, or valine employing a microorganism with enhanced isocitrate lyase and/or malate synthase expression
EP1979486B1 (en) 2006-01-30 2013-04-17 Ajinomoto Co., Inc. L-amino acid producing bacterium and method of producing l-amino acid
JP2009118740A (ja) 2006-03-03 2009-06-04 Ajinomoto Co Inc L−アミノ酸の製造法
JP2010017082A (ja) 2006-10-10 2010-01-28 Ajinomoto Co Inc L−アミノ酸の製造法
JP2010041920A (ja) 2006-12-19 2010-02-25 Ajinomoto Co Inc L−アミノ酸の製造法
CA2675026A1 (en) * 2007-01-12 2008-07-24 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms
JP2010088301A (ja) 2007-02-01 2010-04-22 Ajinomoto Co Inc L−アミノ酸の製造法
JP2010110216A (ja) 2007-02-20 2010-05-20 Ajinomoto Co Inc L−アミノ酸または核酸の製造方法
US8883453B2 (en) * 2007-04-30 2014-11-11 University Of Maryland Codon specific mutagenesis
EP2192170B1 (en) 2007-09-04 2017-02-15 Ajinomoto Co., Inc. Amino acid-producing microorganism and method of producing amino acid
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
JP2011067095A (ja) 2008-01-10 2011-04-07 Ajinomoto Co Inc 発酵法による目的物質の製造法
CN102348806A (zh) 2008-01-23 2012-02-08 味之素株式会社 L-氨基酸的生产方法
CN102177246B (zh) 2008-09-08 2015-02-11 味之素株式会社 生产l-氨基酸的微生物和l-氨基酸的生产方法
JP2012029565A (ja) 2008-11-27 2012-02-16 Ajinomoto Co Inc L−アミノ酸の製造法
WO2011013707A1 (ja) 2009-07-29 2011-02-03 味の素株式会社 L-アミノ酸の製造法
JP2012223091A (ja) 2009-08-25 2012-11-15 Ajinomoto Co Inc L−アミノ酸の製造法
JP2012223092A (ja) 2009-08-28 2012-11-15 Ajinomoto Co Inc L−アミノ酸の製造法
EP2480673B1 (en) 2009-09-27 2018-05-23 OPX Biotechnologies, Inc. Method for producing 3-hydroxypropionic acid and other products
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
JP2013013329A (ja) 2009-11-06 2013-01-24 Ajinomoto Co Inc L−アミノ酸の製造法
CA2781400A1 (en) * 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an organic acid and/or related chemicals
WO2011100608A1 (en) 2010-02-11 2011-08-18 Metabolix, Inc. Process for producing a monomer component from a genetically modified polyhydroxyalkanoate biomass
WO2012103263A2 (en) * 2011-01-25 2012-08-02 Finley Kenneth R Compositions and methods for malate and fumarate production
WO2012103261A2 (en) 2011-01-25 2012-08-02 Finley Kenneth R Compositions and methods for succinate production
EP2495317A1 (en) 2011-03-01 2012-09-05 Technische Universität Hamburg-Harburg Modified phosphoenolpyruvate carboxylase from Corynebacterium glutamicum and uses thereof
WO2012170793A1 (en) 2011-06-08 2012-12-13 Metabolix, Inc. Biorefinery process for thf production
WO2013023140A1 (en) 2011-08-10 2013-02-14 Metabolix, Inc. Post process purification for gamma-butyrolactone production
EP2877568B1 (en) 2012-07-25 2021-04-28 Cargill, Incorporated Yeast cells having reductive tca pathway from pyruvate to succinate and overexpressing an exogenous nad(p)+ transhydrogenase enzyme
KR20150040359A (ko) 2012-08-10 2015-04-14 오피엑스 바이오테크놀로지스, 인크. 지방산 및 지방산 유도된 산물의 생산을 위한 미생물 및 방법
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
EP2976141A4 (en) 2013-03-15 2016-10-05 Cargill Inc FLASHING FOR PRODUCTION CLEANING AND RECOVERY
JP5831669B2 (ja) 2013-05-13 2015-12-09 味の素株式会社 L−アミノ酸の製造法
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
EP3022310B1 (en) 2013-07-19 2019-10-16 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
JP2016192903A (ja) 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのl−アミノ酸の製造方法
ES2761596T3 (es) 2013-10-02 2020-05-20 Ajinomoto Kk Aparato de control de amoniaco y método de control de amoniaco
JP6459962B2 (ja) 2013-10-21 2019-01-30 味の素株式会社 L−アミノ酸の製造法
JP6519476B2 (ja) 2013-10-23 2019-05-29 味の素株式会社 目的物質の製造法
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
CN105132388B (zh) * 2015-09-06 2018-02-23 江南大学 一种酶活性提高的丙酮酸羧化酶突变体r485p及其应用
CN105907730B (zh) * 2016-05-11 2019-06-21 江南大学 一种酶活性提高的丙酮酸羧化酶突变体n1078f及其应用
EP3577227A4 (en) 2017-02-02 2020-12-30 Cargill Inc. GENETICALLY MODIFIED CELLS PRODUCING C6-C10 FATTY ACID DERIVATIVES
MX2020002345A (es) * 2017-09-01 2020-07-13 Univ Niigata Metodo eficiente para producir ambreina.
CN116113699A (zh) * 2020-12-24 2023-05-12 武汉远大弘元股份有限公司 改造的磷酸烯醇丙酮酸羧化酶及其在提高谷氨酸棒杆菌氨基酸产量中的应用
CN115806962A (zh) * 2021-09-15 2023-03-17 中国科学院天津工业生物技术研究所 磷酸烯醇式丙酮酸羧化酶突变体及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2223754B (en) * 1988-09-12 1992-07-22 Degussa Dna encoding phosphoenolpyruvate carboxylase
JPH07108228B2 (ja) * 1990-10-15 1995-11-22 味の素株式会社 温度感受性プラスミド

Also Published As

Publication number Publication date
ATE220099T1 (de) 2002-07-15
HUT73690A (en) 1996-09-30
AU8099194A (en) 1995-03-21
CA2169170A1 (en) 1995-03-02
DE69430919D1 (de) 2002-08-08
HU219600B (hu) 2001-05-28
KR960704029A (ko) 1996-08-31
CA2169170C (en) 2007-01-09
BR9407625A (pt) 1997-01-21
CN1133615A (zh) 1996-10-16
EP0723011A4 (en) 1996-05-21
SK20496A3 (en) 1996-11-06
WO1995006114A1 (fr) 1995-03-02
EP0723011A1 (en) 1996-07-24
CN1179043C (zh) 2004-12-08
KR100337959B1 (ko) 2002-11-23
DE69430919T2 (de) 2003-02-27
EP0723011B1 (en) 2002-07-03
AU682547B2 (en) 1997-10-09
PL181380B1 (pl) 2001-07-31
CZ52496A3 (en) 1996-06-12
SK283369B6 (sk) 2003-06-03
CZ289051B6 (cs) 2001-10-17
PL313119A1 (en) 1996-06-10
MY112250A (en) 2001-05-31
US5919694A (en) 1999-07-06
US5876983A (en) 1999-03-02

Similar Documents

Publication Publication Date Title
AU682547B2 (en) Variant phosphoenolpyruvate carboxylase, gene thereof, and process for producing amino acid
EP0446570A3 (en) Gabapentin and its derivatives for treating neurodegenerative diseases
AU8806291A (en) Chimeric fibroblast growth factor
AU5981580A (en) A process for enzymatic production of peptides
EP1165763A4 (en) HYDANTOINASE VARIANTS WITH IMPROVED PROPERTIES AND THEIR USE FOR THE PRODUCTION OF AMINO ACIDS
EP0552240A4 (en) New method of treating depression
TW260709B (hu)
AU2223601A (en) Process for producing l-amino acid and novel gene
HU9201470D0 (en) Process for the production of new polypeptides that show affininty towards lipoposaccharides
EP0481930A3 (en) Nonlinear peptides hydropathycally complementary to known amino acid sequences, process for the production and uses thereof
GB1441532A (en) Fermentation process for producing amino acids
HUT52561A (en) Process for production of l-amino acid and aminoacidamids
AU7655994A (en) Cloning of a member of the serine-threonine-kinase family
KR100190778B1 (en) Optimized fermentation processes for the preparation of lipocortins in e-coli
MX9200125A (es) Proceso para la produccion de proteinas hidrolizadas, y el producto asi obtenido
EP0316725A3 (de) Verfahren zur enzymatischen Peptidsynthese mit mindestens einer nicht-proteinogenen Aminsäure sowie die neuen, bei der Synthese anfallenden Peptide
IL78543A0 (en) Production of protein
EP0321722A3 (en) Process for obtaining dipeptides
Hayashi et al. Arg 292 arrow right Val) or(Arg 292 arrow right Leu) mutation enhances the reactivity of Escherichia coli aspartate aminotransferase with aromatic amino acids.
Tsuchida et al. Process for producing L-glutamic acid
TH2454EX (th) กรรมวิธีในการผลิตแอล-เฟนิลอะลานีน
TH2454A (th) กรรมวิธีในการผลิตแอล-เฟนิลอะลานีน
GR970100090A (el) Διαδικασια παραγωγης 1,2-διμεθυλ-3-υδροξυπυριδ-4-ονης

Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees